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ClinicalTrials.gov public records Last synced Oct 20, 2026, 8:09 PM EDT

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Showing 1–24 of 118 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Hyperbaric Oxygen Clear all
Terminated No phase listed Observational

Hyperbaric Oxygen Therapy in Chronic Traumatic Brain Injury or Post-Traumatic Stress Disorder

NCT01105962
View directory record Official record
Conditions
Traumatic Brain Injury, Post-traumatic Stress Disorder
Interventions
Not listed
Lead sponsor
International Hyperbaric Medical Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
10
States / cities
San Francisco, California • Boulder, Colorado • Delray Beach, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 20, 2016 · Synced Oct 20, 2026, 8:09 PM EDT
Suspended No phase listed Observational

Outcome Assessment in Patients Treated With Hyperbaric Oxygen Using OxyVu Tissue Oxygenation Monitoring System

NCT00768027
View directory record Official record
Conditions
Wounds
Interventions
Not listed
Lead sponsor
HyperMed
Industry
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
3
States / cities
Long Beach, California • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 4, 2009 · Synced Oct 20, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Test of Chamber Pressure to Divers and Chamber Attendants

NCT01430325
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Hyperbaric Oxygen (1.5 atm abs), Sham Chamber Session
Drug
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
2
States / cities
Murray, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 15, 2013 · Synced Oct 20, 2026, 8:09 PM EDT
Withdrawn Not applicable Interventional

HBOT and Exercise Recovery

NCT05924035
View directory record Official record
Conditions
Exercise Recovery
Interventions
HBOT
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 14, 2023 · Synced Oct 20, 2026, 8:09 PM EDT
Terminated Not applicable Interventional

Hyperbaric Oxygen for COVID-19 Patients With Moderate to Severe Hypoxemia

NCT04619719
View directory record Official record
Conditions
Covid19
Interventions
Hyperbaric Oxygen Therapy (HBOT)
Device
Lead sponsor
Legacy Health System
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
3
States / cities
Bozeman, Montana • Mineola, New York • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 9, 2023 · Synced Oct 20, 2026, 8:09 PM EDT
Completed No phase listed Observational

Study to Compare Verbal Scores of Children Diagnosed With ASD Who Received Hyperbaric Treatment To Those Who Did Not

NCT06043284
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Hyperbaric Oxygen Therapy
Device
Lead sponsor
Oxford Recovery Center
Other
Eligibility
2 Years to 17 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Brighton, Michigan • Troy, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 20, 2026, 8:09 PM EDT
Completed Phase 1 Interventional

Hyperbaric Oxygen Therapy (HBOT) in Chronic Traumatic Brain Injury (TBI)/Post Concussion Syndrome (PCS) and TBI/Post-Traumatic Stress Disorder (PTSD)

NCT00760734
View directory record Official record
Conditions
TBI (Traumatic Brain Injury), Post Concussion Syndrome, Post Traumatic Stress Disorder, Chronic Post Traumatic Stress Disorder
Interventions
Low pressure hyperbaric oxygen therapy
Drug
Lead sponsor
Paul G. Harch, M.D.
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 20, 2026, 8:09 PM EDT
Not yet recruiting Not applicable Interventional

Hyperbaric Oxygen Treatment for Necrotizing Fasciitis and Necrotizing Soft Tissue Infections

NCT07170020
View directory record Official record
Conditions
Necrotizing Fascitis
Interventions
Hyperbaric Oxygen Therapy
Procedure
Lead sponsor
Corewell Health West
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 12, 2025 · Synced Oct 20, 2026, 8:09 PM EDT
Not listed Phase 2 Interventional

Hyperbaric Hyperoxygenation With Radiotherapy and Temozolomide in Adults With Newly Diagnosed Glioblastoma

NCT00936052
View directory record Official record
Conditions
Glioblastomas, Gliosarcoma
Interventions
Hyperbaric Oxygen Therapy
Other
Lead sponsor
Neurological Surgery, P.C.
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
2
States / cities
Commack, New York • Great Neck, New York
Source: ClinicalTrials.gov public record
Updated Jul 16, 2010 · Synced Oct 20, 2026, 8:09 PM EDT
Completed No phase listed Observational

Functional and Anatomical Magnetic Resonance Imaging (MRI) of Chronic Brain Injury and Hyperbaric Oxygen (HBO2) Study Subjects

NCT01126515
View directory record Official record
Conditions
Brain Injury, Sequelae, Stroke, Anoxia, Trauma
Interventions
Magnetic Resonance Imaging, Computed Tomography Angiography
Procedure
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years to 80 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 29, 2020 · Synced Oct 20, 2026, 8:09 PM EDT
Completed Not applicable Interventional

Use of Hyperbaric Oxygen Therapy to Treat COVID-19 Patients With Respiratory Distress

NCT04800120
View directory record Official record
Conditions
Covid19
Interventions
Hyperbaric Oxygen Therapy
Other
Lead sponsor
Steward St. Elizabeth's Medical Center of Boston, Inc.
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Taunton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 2, 2023 · Synced Oct 20, 2026, 8:09 PM EDT
Not listed Not applicable Interventional

Effects of Hyperbaric Oxygenation Therapy on Adaptive, Aberrant and Stereotyped Behaviors in Children With Autism

NCT00404846
View directory record Official record
Conditions
Autism
Interventions
Hyperbaric Oxygenation Therapy
Procedure
Lead sponsor
The Center for Autism and Related Disorders
Other
Eligibility
2 Years to 14 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Tarzana, California
Source: ClinicalTrials.gov public record
Updated May 5, 2009 · Synced Oct 20, 2026, 8:09 PM EDT
Not listed Phase 4 Interventional

Can Hyperbaric Oxygen Improve Erectile Function Following Surgery for Prostate Cancer

NCT00906269
View directory record Official record
Conditions
Impotence, Prostatic Neoplasms
Interventions
Sildenafil therapy plus post-NSRRP HBO2T, Sildenafil therapy plus sham post-NSRRP HBO2T
Drug
Lead sponsor
Hartford Hospital
Other
Eligibility
40 Years to 65 Years · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2021
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 20, 2019 · Synced Oct 20, 2026, 8:09 PM EDT
Completed No phase listed Observational

Tissue Perfusion and Blood Flow Monitoring Technology

NCT01139567
View directory record Official record
Conditions
Wounds and Injuries
Interventions
Not listed
Lead sponsor
CW Optics, Inc.
Industry
Eligibility
21 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 2, 2013 · Synced Oct 20, 2026, 8:09 PM EDT
Not listed Phase 2Phase 3 Interventional Accepts healthy volunteers

A Dosing Study of Hyperbaric Oxygen Therapy (HBOT) on Epigenetic Aging

NCT05297019
View directory record Official record
Conditions
Aging
Interventions
Hyperbaric Oxygen Therapy
Procedure
Lead sponsor
TruDiagnostic
Industry
Eligibility
40 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Florham Park, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Oct 20, 2026, 8:09 PM EDT
Withdrawn Not applicable Interventional

The Use of Hyperbaric Oxygen to Increase the Blood Supply in the Injured, But Still Alive Tissue, Around an Old Stroke

NCT01985100
View directory record Official record
Conditions
Ischemic Cerebrovascular Accident
Interventions
hyperbaric oxygen chamber
Other
Lead sponsor
John Davidson
Other
Eligibility
50 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 27, 2017 · Synced Oct 20, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Pre-dive Ketone Food Products on Latency to CNS Oxygen Toxicity (Aim 2)

NCT05831228
View directory record Official record
Conditions
Oxygen Toxicity
Interventions
Ketogenic food products, Control: Placebo
Dietary Supplement
Lead sponsor
Duke University
Other
Eligibility
18 Years to 39 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 20, 2026, 8:09 PM EDT
Withdrawn Early Phase 1 Interventional

Effect of Adjuvant Hyperbaric Oxygen Therapy on Bells Palsy Outcome

NCT03457025
View directory record Official record
Conditions
Bell Palsy
Interventions
Oral Corticosteroids, Oral antivirals, Hyperbaric Oxygen Therapy
Drug · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 29, 2020 · Synced Oct 20, 2026, 8:09 PM EDT
Completed Phase 4 Interventional Results available

Pseudoephedrine Prophylaxis for Prevention of Middle Ear Barotrauma in Hyperbaric Oxygen Therapy

NCT04332211
View directory record Official record
Conditions
Barotrauma;Ear
Interventions
Hyperbaric Oxygen Therapy, Pseudoephedrine 60 MG, Placebo oral tablet
Procedure · Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Oct 20, 2026, 8:09 PM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Hyperbaric Oxygen, Neutrophil-oxidative Burst, and Cytokines

NCT02563678
View directory record Official record
Conditions
Infection
Interventions
Hyperbaric Oxygen, Hyperbaric Air/Oxygen, Normobaric oxygen
Drug · Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
2
States / cities
Murray, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 4, 2022 · Synced Oct 20, 2026, 8:09 PM EDT
Completed Phase 2 Interventional Results available

Prospective Trial Comparing Response to Hyperbaric Oxygen Treatment in Patients With Interstitial Cystitis

NCT01479725
View directory record Official record
Conditions
Interstitial Cystitis
Interventions
HBOT
Procedure
Lead sponsor
Kenneth Peters, MD
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 3, 2017 · Synced Oct 20, 2026, 8:09 PM EDT
Not listed Phase 1 Interventional

Hyperbaric Oxygen Therapy and SPECT Brain Imaging in Traumatic Brain Injury

NCT00594503
View directory record Official record
Conditions
Residual Neurological, Cognitive, Emotional, Behavioral Effects From Traumatic Brain Injury
Interventions
Hyperbaric oxygen therapy
Drug
Lead sponsor
Paul G. Harch, M.D.
Other
Eligibility
Not listed
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
Marrero, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 20, 2026, 8:09 PM EDT
Terminated Not applicable Interventional Results available

An Evaluation of Hyperbaric Treatments for Children With Cerebral Palsy

NCT00290186
View directory record Official record
Conditions
Cerebral Palsy, Cerebral Palsy, Spastic
Interventions
Hyperbaric Oxygen Treatment, Hyperbaric Air Treatment
Device
Lead sponsor
Dayton Children's Hospital
Other
Eligibility
3 Years to 8 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
2
States / cities
Dayton, Ohio • Wpafb, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 28, 2014 · Synced Oct 20, 2026, 8:09 PM EDT
Terminated Not applicable Interventional

Effect of Hyperbaric Oxygen on Functional Connectivity in Patients With Cerebral Small Vessel Disease

NCT02890888
View directory record Official record
Conditions
Cerebral Small Vessel Diseases
Interventions
hyperbaric oxygen treatment
Other
Lead sponsor
St. Luke's Hospital, Chesterfield, Missouri
Other
Eligibility
50 Years to 90 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
3
States / cities
Chesterfield, Missouri • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 27, 2017 · Synced Oct 20, 2026, 8:09 PM EDT