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ClinicalTrials.gov public records Last synced Oct 4, 2026, 9:56 PM EDT

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Showing 25–48 of 120 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Hyperbaric Oxygen therapy Clear all
Not listed Not applicable Interventional

Carbon Monoxide Monitoring and Emergency Treatment

NCT00841165
View directory record Official record
Conditions
Carbon Monoxide Poisoning
Interventions
Continuous Positive Airway Pressure, Non-rebreather oxygen mask
Device
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Apr 2, 2010 · Synced Oct 4, 2026, 9:56 PM EDT
Withdrawn No phase listed Observational

Saliva, Hyperbaric Oxygen Therapy, & Gland Function: A Prospective Study

NCT01532479
View directory record Official record
Conditions
Osteoradionecrosis of the Jaw, Xerostomia
Interventions
Not listed
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Apr 27, 2017 · Synced Oct 4, 2026, 9:56 PM EDT
Completed Phase 1 Interventional

Hyperbaric Oxygen Therapy (HBOT) in Chronic Traumatic Brain Injury (TBI)/Post Concussion Syndrome (PCS) and TBI/Post-Traumatic Stress Disorder (PTSD)

NCT00760734
View directory record Official record
Conditions
TBI (Traumatic Brain Injury), Post Concussion Syndrome, Post Traumatic Stress Disorder, Chronic Post Traumatic Stress Disorder
Interventions
Low pressure hyperbaric oxygen therapy
Drug
Lead sponsor
Paul G. Harch, M.D.
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 4, 2026, 9:56 PM EDT
Terminated Not applicable Interventional

Effect of HBO on Functional Connectivity of Resting State Networks in Patients With Cerebral Small Vessel Disease

NCT02232958
View directory record Official record
Conditions
Encephalopathy, White Matter Hyperintensities, Impaired Oxygen Delivery
Interventions
Hyperbaric Oxygen Treatment
Other
Lead sponsor
St. Luke's Hospital, Chesterfield, Missouri
Other
Eligibility
50 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
3
States / cities
Chesterfield, Missouri • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 30, 2017 · Synced Oct 4, 2026, 9:56 PM EDT
Completed Not applicable Interventional

A Controlled Trial of the Clinical Effects of Hyperbaric Therapy in Autistic Children

NCT00335790
View directory record Official record
Conditions
Autism
Interventions
Hyperbaric Therapy
Procedure
Lead sponsor
International Hyperbarics Association
Other
Eligibility
2 Years to 7 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
4
States / cities
Phoenix, Arizona • Melbourne, Florida • Charlottesville, Virginia + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 10, 2007 · Synced Oct 4, 2026, 9:56 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Stem Cell Quantification In Peripheral Blood After Hyperbaric Oxygen Therapy Treatments

NCT01740908
View directory record Official record
Conditions
Changes in Peripheral Blood Population Numbers and Type.
Interventions
Hyperbaric Oxygen Treatment
Other
Lead sponsor
Restorix Research Institute, LLLP
Other
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Anacortes, Washington
Source: ClinicalTrials.gov public record
Updated Dec 4, 2012 · Synced Oct 4, 2026, 9:56 PM EDT
Recruiting Phase 2 Interventional

Hyperbaric Oxygen Therapy for Veterans With TBI and PCS: A Biomarker Study

NCT07849465
View directory record Official record
Conditions
Traumatic Brain Injury (TBI) Patients, Post Concussive Symptoms, PTSD
Interventions
Hyperbaric Oxygen Therapy (HBOT)
Drug
Lead sponsor
Summit Hyperbarics and Wellness
Other
Eligibility
18 Years to 75 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 4, 2026, 9:56 PM EDT
Withdrawn Not applicable Interventional

The Use of Hyperbaric Oxygen to Increase the Blood Supply in the Injured, But Still Alive Tissue, Around an Old Stroke

NCT01985100
View directory record Official record
Conditions
Ischemic Cerebrovascular Accident
Interventions
hyperbaric oxygen chamber
Other
Lead sponsor
John Davidson
Other
Eligibility
50 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 27, 2017 · Synced Oct 4, 2026, 9:56 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Hyperbaric VO2max Study

NCT02356900
View directory record Official record
Conditions
Exercise Training
Interventions
Hyperoxic hyperbaric interval exercise training, Normoxic, normobaric, interval exercise training, Oxygen
Procedure · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 35 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 17, 2017 · Synced Oct 4, 2026, 9:56 PM EDT
Withdrawn Phase 2 Interventional

Hyperbaric Oxygen Therapy for Hematopoietic Progenitor Cell Collection in Poor Mobilizers

NCT02682953
View directory record Official record
Conditions
Bone Marrow Transplantation, Hematopoietic Stem Cells, Multiple Myeloma, Lymphoma
Interventions
Neupogen, Hyperbaric oxygen therapy, Plerixafor
Drug · Procedure
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 11, 2019 · Synced Oct 4, 2026, 9:56 PM EDT
Terminated Early Phase 1 Interventional

Hyperbaric Oxygen Therapy for Inflammatory Conditions of the Urinary Bladder

NCT03143920
View directory record Official record
Conditions
Chronic Interstitial Cystitis, Painful Bladder Syndrome, Recurrent Urinary Tract Infection
Interventions
Hyperbaric Oxygen Therapy-
Combination Product
Lead sponsor
University of California, San Diego
Other
Eligibility
35 Years to 70 Years · Female only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 11, 2022 · Synced Oct 4, 2026, 9:56 PM EDT
Not listed Phase 1 Interventional

Hyperbaric Oxygen Therapy and SPECT Brain Imaging in Traumatic Brain Injury

NCT00594503
View directory record Official record
Conditions
Residual Neurological, Cognitive, Emotional, Behavioral Effects From Traumatic Brain Injury
Interventions
Hyperbaric oxygen therapy
Drug
Lead sponsor
Paul G. Harch, M.D.
Other
Eligibility
Not listed
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
Marrero, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 4, 2026, 9:56 PM EDT
Completed Phase 2 Interventional Results available

mTBI Mechanisms of Action of HBO2 for Persistent Post-Concussive Symptoms

NCT01611194
View directory record Official record
Conditions
Traumatic Brain Injury With Brief Loss of Consciousness, Post-Concussion Syndrome
Interventions
Hyperbaric oxygen (HBO2) at 1.5 atms, Sham control 1.2 atms
Drug
Lead sponsor
U.S. Army Medical Research and Development Command
Federal
Eligibility
18 Years to 65 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
5
States / cities
Colorado Springs, Colorado • Fort Carson, Colorado • Jacksonville, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2018 · Synced Oct 4, 2026, 9:56 PM EDT
Completed Phase 2 Interventional Results available

Hyperbaric Oxygen Therapy (HBO2) for Persistent Post-concussive Symptoms After Mild Traumatic Brain Injury (mTBI)

NCT01306968
View directory record Official record
Conditions
Post-concussive Symptoms, Traumatic Brain Injury
Interventions
hyperbaric oxygen, sham hyperbaric air
Drug · Other
Lead sponsor
U.S. Army Medical Research and Development Command
Federal
Eligibility
18 Years to 65 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
5
States / cities
Camp Pendleton, California • Fort Carson, Colorado • Fort Gordon, Georgia + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2014 · Synced Oct 4, 2026, 9:56 PM EDT
Terminated Phase 2 Interventional

Acute Post-Radiation Hyperbaric Oxygen (HBO2) for Breast Cancer Patients Who Have Recently Completed Radiation Therapy

NCT03916068
View directory record Official record
Conditions
Breast Cancer
Interventions
Hyperbaric Oxygen Therapy, Trental Pill, Vitamin E
Procedure · Drug · Dietary Supplement
Lead sponsor
Legacy Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 4, 2023 · Synced Oct 4, 2026, 9:56 PM EDT
Completed Phase 2 Interventional Results available

Hyperbaric Oxygen Therapy for Lung Transplantation

NCT02363959
View directory record Official record
Conditions
Disorder Related to Lung Transplantation, Central Airway Stenosis, Airway Exudative Plaques, Airway Complications Post-Lung Transplantation
Interventions
Hyperbaric Oxygen Therapy, Endobronchial Biopsy of Airway Epithelium
Drug · Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 4, 2026, 9:56 PM EDT
Completed No phase listed Observational

Tissue Perfusion and Blood Flow Monitoring Technology

NCT01139567
View directory record Official record
Conditions
Wounds and Injuries
Interventions
Not listed
Lead sponsor
CW Optics, Inc.
Industry
Eligibility
21 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 2, 2013 · Synced Oct 4, 2026, 9:56 PM EDT
Terminated Not applicable Interventional

Hyperbaric Oxygen for Wagner II Diabetic Lower Extremity Ulcers

NCT01954901
View directory record Official record
Conditions
Wagner Grade 2 Lower Extremity Ulcers
Interventions
Hyperbaric oxygen therapy, Hyperbaric room air
Device
Lead sponsor
David Grant U.S. Air Force Medical Center
Federal
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Travis Air Force Base, California
Source: ClinicalTrials.gov public record
Updated Apr 17, 2020 · Synced Oct 4, 2026, 9:56 PM EDT
Not listed No phase listed Observational

Compassionate Use of Hyperbaric Oxygen Therapy

NCT04386265
View directory record Official record
Conditions
COVID-19
Interventions
Not listed
Lead sponsor
SerenaGroup, Inc.
Network
Eligibility
18 Years and older
Enrollment
100 participants
Timeline
2020 – 2022
U.S. locations
10
States / cities
Batesville, Arkansas • Monterey, California • Tampa, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2020 · Synced Oct 4, 2026, 9:56 PM EDT
Not listed Phase 4 Interventional

Can Hyperbaric Oxygen Improve Erectile Function Following Surgery for Prostate Cancer

NCT00906269
View directory record Official record
Conditions
Impotence, Prostatic Neoplasms
Interventions
Sildenafil therapy plus post-NSRRP HBO2T, Sildenafil therapy plus sham post-NSRRP HBO2T
Drug
Lead sponsor
Hartford Hospital
Other
Eligibility
40 Years to 65 Years · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2021
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 20, 2019 · Synced Oct 4, 2026, 9:56 PM EDT
Not listed Phase 1 Interventional

Hyperbaric Oxygen Therapy and SPECT Brain Imaging in Cerebral Decompression Illness

NCT02105194
View directory record Official record
Conditions
Cerebral Decompression Illness, All Phases
Interventions
Hyperbaric oxygen therapy
Drug
Lead sponsor
Paul G. Harch, M.D.
Other
Eligibility
Not listed
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
Marrero, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 4, 2026, 9:56 PM EDT
Terminated Not applicable Interventional Results available

Hyperbaric Oxygen for COVID-19 Patients

NCT04332081
View directory record Official record
Conditions
COVID-19
Interventions
hyperbaric oxygen therapy (HBOT)
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated Jun 22, 2021 · Synced Oct 4, 2026, 9:56 PM EDT
Completed Not applicable Interventional

Effect of Total Compression Time and Rate (Slope) on Incidence of Symptomatic ETD and MEB: A Phase II Prospective Study.

NCT04776967
View directory record Official record
Conditions
Eustachian Tube Dysfunction, Middle Ear Barotrauma, Middle Ear Disease, Middle Ear; Injury, Pressure Injury, Ear Barotrauma
Interventions
Hyperbaric Compression Profile
Procedure
Lead sponsor
Northwell Health
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Sleepy Hollow, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2021 · Synced Oct 4, 2026, 9:56 PM EDT
Completed Not applicable Interventional

Effect of Hyperbaric Therapy on Markers of Oxidative Stress in Children With Autism

NCT00263367
View directory record Official record
Conditions
Autism, Oxidative Stress
Interventions
Hyperbaric Oxygen
Other
Lead sponsor
The International Child Development Resource Center
Other
Eligibility
5 Years to 12 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Melbourne, Florida
Source: ClinicalTrials.gov public record
Updated Jun 22, 2011 · Synced Oct 4, 2026, 9:56 PM EDT