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Showing 25–43 of 19 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Hyperbaric chamber Clear all
Not listed Phase 2 Interventional

Hyperbaric Radiation Sensitization of Head and Neck Cancers

NCT03843671
View directory record Official record
Conditions
Squamous Cell Carcinoma of the Head and Neck
Interventions
Hyperbaric oxygen, Hyperbaric chamber
Drug · Device
Lead sponsor
National Baromedical Services
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
4
States / cities
Rochester, Minnesota • Lebanon, New Hampshire • Columbia, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2019 · Synced Sep 27, 2026, 7:13 AM EDT
Completed Not applicable Interventional

Use of Hyperbaric Oxygen Therapy to Treat COVID-19 Patients With Respiratory Distress

NCT04800120
View directory record Official record
Conditions
Covid19
Interventions
Hyperbaric Oxygen Therapy
Other
Lead sponsor
Steward St. Elizabeth's Medical Center of Boston, Inc.
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Taunton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 1, 2023 · Synced Sep 27, 2026, 7:13 AM EDT
Completed Not applicable Interventional Results available

Hyperbaric Oxygen Therapy for Cognition in Diabetic Elderly at High Dementia Risk

NCT03036254
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
HBOT intervention, Sham intervention
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
65 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
2
States / cities
New York, New York • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 10, 2025 · Synced Sep 27, 2026, 7:13 AM EDT
Terminated Not applicable Interventional Results available

Study of Hyperbaric Oxygen Therapy in Addition to Standard Growth Factor Support for Hematopoietic Progenitor/Stem Cell Mobilization

NCT01449539
View directory record Official record
Conditions
Multiple Myeloma
Interventions
Hyperbaric Oxygen Therapy
Drug
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Feb 22, 2015 · Synced Sep 27, 2026, 7:13 AM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Hyperbaric Oxygen, Neutrophil-oxidative Burst, and Cytokines

NCT02563678
View directory record Official record
Conditions
Infection
Interventions
Hyperbaric Oxygen, Hyperbaric Air/Oxygen, Normobaric oxygen
Drug · Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
2
States / cities
Murray, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 3, 2022 · Synced Sep 27, 2026, 7:13 AM EDT
Terminated Early Phase 1 Interventional

Hyperbaric Oxygen Therapy for Inflammatory Conditions of the Urinary Bladder

NCT03143920
View directory record Official record
Conditions
Chronic Interstitial Cystitis, Painful Bladder Syndrome, Recurrent Urinary Tract Infection
Interventions
Hyperbaric Oxygen Therapy-
Combination Product
Lead sponsor
University of California, San Diego
Other
Eligibility
35 Years to 70 Years · Female only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2022 · Synced Sep 27, 2026, 7:13 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Hyperbaric VO2max Study

NCT02356900
View directory record Official record
Conditions
Exercise Training
Interventions
Hyperoxic hyperbaric interval exercise training, Normoxic, normobaric, interval exercise training, Oxygen
Procedure · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 35 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 16, 2017 · Synced Sep 27, 2026, 7:13 AM EDT
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

Rhu-pGSN to Mitigate Proinflammatory Responses to Decompression in Healthy SCUBA Divers

NCT06216366
View directory record Official record
Conditions
Decompression Sickness
Interventions
Sodium Chloride 0.9% Inj pre-exposure, Sodium Chloride 0.9% Inj post-exposure, Recombinant human plasma gelsolin pre-exposure, Recombinant human plasma gelsolin post-exposure, Hyperbaric chamber
Drug · Other
Lead sponsor
BioAegis Therapeutics Inc.
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 27, 2026, 7:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Test of Chamber Pressure to Divers and Chamber Attendants

NCT01430325
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Hyperbaric Oxygen (1.5 atm abs), Sham Chamber Session
Drug
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
2
States / cities
Murray, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 14, 2013 · Synced Sep 27, 2026, 7:13 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Hyperbaric Oxygen Therapy on Surgical Wound Healing

NCT01605110
View directory record Official record
Conditions
Edema, Ecchymosis
Interventions
Hyperbaric oxygen treatment, Air sham
Drug
Lead sponsor
Restorix Research Institute, LLLP
Other
Eligibility
40 Years to 85 Years
Enrollment
164 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Issaquah, Washington
Source: ClinicalTrials.gov public record
Updated Dec 4, 2012 · Synced Sep 27, 2026, 7:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of High-Intensity Interval Training (HIT) While in a Hyperoxic-Hyperbaric Environment on Exercise Performance

NCT02941939
View directory record Official record
Conditions
Exercise Performance
Interventions
Hyperbaric chamber, Ambient pressure
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years to 40 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated May 21, 2018 · Synced Sep 27, 2026, 7:13 AM EDT
Terminated Not applicable Interventional

Effect of Hyperbaric Oxygen on Functional Connectivity in Patients With Cerebral Small Vessel Disease

NCT02890888
View directory record Official record
Conditions
Cerebral Small Vessel Diseases
Interventions
hyperbaric oxygen treatment
Other
Lead sponsor
St. Luke's Hospital, Chesterfield, Missouri
Other
Eligibility
50 Years to 90 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
3
States / cities
Chesterfield, Missouri • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Sep 27, 2026, 7:13 AM EDT
Withdrawn Not applicable Interventional

HBOT and Exercise Recovery

NCT05924035
View directory record Official record
Conditions
Exercise Recovery
Interventions
HBOT
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced Sep 27, 2026, 7:13 AM EDT
Completed Phase 2 Interventional Results available

Hyperbaric Oxygen Therapy for Lung Transplantation

NCT02363959
View directory record Official record
Conditions
Disorder Related to Lung Transplantation, Central Airway Stenosis, Airway Exudative Plaques, Airway Complications Post-Lung Transplantation
Interventions
Hyperbaric Oxygen Therapy, Endobronchial Biopsy of Airway Epithelium
Drug · Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 27, 2026, 7:13 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of HBO on Glucose in Patients With DM

NCT04261738
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
Interventions
Hyperbaric Oxygen
Device
Lead sponsor
Legacy Health System
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 27, 2026, 7:13 AM EDT
Completed No phase listed Observational

Study to Compare Verbal Scores of Children Diagnosed With ASD Who Received Hyperbaric Treatment To Those Who Did Not

NCT06043284
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Hyperbaric Oxygen Therapy
Device
Lead sponsor
Oxford Recovery Center
Other
Eligibility
2 Years to 17 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Brighton, Michigan • Troy, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 20, 2023 · Synced Sep 27, 2026, 7:13 AM EDT
Not listed Phase 2 Interventional

Hyperbaric Hyperoxygenation With Radiotherapy and Temozolomide in Adults With Newly Diagnosed Glioblastoma

NCT00936052
View directory record Official record
Conditions
Glioblastomas, Gliosarcoma
Interventions
Hyperbaric Oxygen Therapy
Other
Lead sponsor
Neurological Surgery, P.C.
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
2
States / cities
Commack, New York • Great Neck, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2010 · Synced Sep 27, 2026, 7:13 AM EDT
Withdrawn Not applicable Interventional

The Use of Hyperbaric Oxygen to Increase the Blood Supply in the Injured, But Still Alive Tissue, Around an Old Stroke

NCT01985100
View directory record Official record
Conditions
Ischemic Cerebrovascular Accident
Interventions
hyperbaric oxygen chamber
Other
Lead sponsor
John Davidson
Other
Eligibility
50 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Sep 27, 2026, 7:13 AM EDT
Not listed Phase 3 Interventional

Hyperbaric Oxygen Treatment to Treat Mild Traumatic Brain Injury (mTBI)/Persistent Post-Concussion Syndrome (PPCS)

NCT02089594
View directory record Official record
Conditions
Post-Concussion Syndrome, Traumatic Brain Injury
Interventions
Hyperbaric Oxygen, No Hyperbaric Oxygen
Drug
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years to 65 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Sep 27, 2026, 7:13 AM EDT