Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 8, 2026, 9:02 PM EDT

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Showing 1–24 of 501 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Hypertension (HTN)
Interventions
IN-HOME BP
Other
Lead sponsor
Anita Misra-Hebert
Other
Eligibility
18 Years to 85 Years
Enrollment
1,520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Chronic Kidney Diseases, High Blood Pressure
Interventions
DASH diet counseling
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Renal Failure Chronic Requiring Hemodialysis
Interventions
intensive sodium management
Other
Lead sponsor
Renal Research Institute
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
3
States / cities
New York, New York
Terminated No phase listed Observational

Pediatric Hypertension Registry (PHREG)

NCT03305562
Conditions
Hypertension, Pediatric Disorder
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Up to 17 Years
Enrollment
179 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
2
States / cities
Atlanta, Georgia • Winston-Salem, North Carolina
Conditions
Blood Pressure, Medication Adherence
Interventions
Electronic Health Record (EHR) Enabled Teamlets
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
1,842 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Conditions
Diabetes Mellitus, Type 2
Interventions
iDSMES, Standard of Care
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
13 Years to 84 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Galveston, Texas
Conditions
ESRD, Hemodialysis Complication, Blood Pressure
Interventions
TAKE vs. HOLD
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Menlo Park, California • San Carlos, California
Conditions
Severe Hypertension, Hypertension
Interventions
Emergency Department-Initiated Team-Based Care, Usual Care
Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 85 Years
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
4
States / cities
Dearborn, Michigan • Detroit, Michigan • Wyandotte, Michigan
Recruiting Not applicable Interventional

The GUARDIAN Trial

NCT04884802
Conditions
Blood Pressure
Interventions
Tight blood pressure management, Routine blood pressure management
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
45 Years and older
Enrollment
6,254 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
6
States / cities
Omaha, Nebraska • Wake Forest, North Carolina • Cleveland, Ohio + 1 more
Conditions
Hypertension
Interventions
Nebivolol, Metoprolol ER (TM)
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years to 79 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
Houston, Texas
Conditions
Preeclampsia With Severe Features, Chronic Hypertension in Obstetric Context
Interventions
Experimental dosing of labetalol, Standard dosing of labetalol
Drug · Other
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Albany, New York
Conditions
Hypertension
Interventions
Sharing Intervention
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Symptomatic Neurogenic Orthostatic Hypertension, nOH
Interventions
Ampreloxetine
Drug
Lead sponsor
Theravance Biopharma
Industry
Eligibility
18 Years to 80 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Miami, Florida • Orlando, Florida
Conditions
Hypertension
Interventions
Precision Nudging for Hypertension Management
Behavioral
Lead sponsor
Lirio
Industry
Eligibility
18 Years and older
Enrollment
12,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Greensboro, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Home Blood Pressure Telemonitoring and Case Management to Control Hypertension

NCT00781365
Conditions
Hypertension
Interventions
Telemonitors and pharmacy management
Other
Lead sponsor
HealthPartners Institute
Other
Eligibility
21 Years and older
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Minneapolis, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers

Using Nonpharmacological Approaches in Hypertension Prevention and Management

NCT06490575
Conditions
High Blood Pressure, Hypertension
Interventions
Educational Intervention Based on Protection Motivation Theory to Improve Knowledge and Promote Nonpharmacological Approaches to Prevent and Manage Hypertension among Adults
Other
Lead sponsor
Kansas State University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Manhattan, Kansas
Conditions
Type 2 Diabetes, Hypertension, Hyperlipidemia
Interventions
home health/primary care collaboration
Behavioral
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
30 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
The Bronx, New York
Conditions
Uncontrolled Hypertension
Interventions
Resource information, Community Health Worker (CHW) assistance, Medically-tailored Meals (MTM)
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Cigarette Smoking, Hypertension
Interventions
Varenicline, behavioral therapy
Drug · Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Pulmonary Arterial Hypertension
Interventions
Ranolazine, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 72 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Pulmonary Arterial Hypertension
Interventions
i.v. selexipag, oral selexipag (Uptravi)
Drug
Lead sponsor
Actelion
Industry
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
4
States / cities
La Jolla, California • Boston, Massachusetts • Cleveland, Ohio + 1 more
Completed Not applicable Interventional Accepts healthy volunteers

Prevalence, Awareness and Management of Hypertension in Acute Care Personnel

NCT01655654
Conditions
Hypertension
Interventions
Physical activity, Dietary, Primary care provider visit
Behavioral · Other
Lead sponsor
Providence Health & Services
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Olympia, Washington
Completed No phase listed Observational Accepts healthy volunteers Results available

A Mixed Methods Approach to the Development and Testing of the Measure of Drug Self-Management (MeDS)

NCT01998269
Conditions
Diabetes, Hypertension
Interventions
Not listed
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Diabetes Mellitus, Hypertension
Interventions
NOTES, AUDIO
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
1,022 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
3
States / cities
Manchester, New Hampshire • Nashville, Tennessee • Galveston, Texas