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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Hyperthermia System Clear all
Recruiting No phase listed Observational

Thermodynamic Model of Hyperthermia in Humans Undergoing HIPEC

NCT05426928
View directory record Official record
Conditions
HIPEC
Interventions
Additional temperature monitoring/recording
Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Sep 16, 2026, 1:25 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Knee Pain Related to Osteoarthritis

NCT05882812
View directory record Official record
Conditions
Osteo Arthritis Knee, Arthritis
Interventions
Sustained Acoustic Device with 2.5% Diclofenac Patch, Sustained Acoustic Device with 0% Diclofenac Patch, 2.5% Diclofenac Patches
Device · Drug
Lead sponsor
ZetrOZ, Inc.
Industry
Eligibility
35 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
3
States / cities
Stamford, Connecticut • Trumbull, Connecticut • Dryden, New York
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Sep 16, 2026, 1:25 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Whole Body Hyperthermia & Combat-Related Posttraumatic Stress Disorder (PTSD)

NCT02077972
View directory record Official record
Conditions
Post Traumatic Stress Disorder (PTSD)
Interventions
High intensity whole-body infrared heating
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 9, 2015 · Synced Sep 16, 2026, 1:25 PM EDT
Withdrawn Not applicable Interventional

Robot-Assisted Ultrasound for Thermal Ablative Therapy in Treating Patients With Small Kidney Masses Undergoing Surgery

NCT02370342
View directory record Official record
Conditions
Renal Carcinoma, Renal Mass
Interventions
Robot-Assisted Laparoscopic Surgery, High-Intensity Focused Ultrasound Ablation, Therapeutic Laparoscopic Surgery, Sonatherm 600i Ultrasonic Lesion Generating System
Procedure · Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 19, 2017 · Synced Sep 16, 2026, 1:25 PM EDT
Withdrawn Phase 1 Interventional

HIFU Hyperthermia With Liposomal Doxorubicin (DOXIL) for Relapsed or Refractory Pediatric and Young Adult Solid Tumors

NCT02557854
View directory record Official record
Conditions
Rhabdomyosarcoma, Neuroblastoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Desmoid
Interventions
Doxorubicin HCl liposomal injection, Philips Sonalleve MR-HIFU Hyperthermia
Drug · Device
Lead sponsor
Theodore Laetsch
Other
Eligibility
1 Year to 40 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 18, 2019 · Synced Sep 16, 2026, 1:25 PM EDT
Completed Phase 3 Interventional

Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment

NCT00008359
View directory record Official record
Conditions
Cancer
Interventions
caspofungin acetate, liposomal amphotericin B
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
16 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2000
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 17, 2013 · Synced Sep 16, 2026, 1:25 PM EDT
Not yet recruiting Not applicable Interventional

Feasibility of HISA During TURBT for NMIBC

NCT07817173
View directory record Official record
Conditions
Bladder Cancer, Bladder (Urothelial, Transitional Cell) Cancer Resectable (Pre-Cystectomy), Non-muscle Invasive Bladder Cancer (NMIBC), Non-Muscle Invasive Bladder Neoplasms, Non-muscle Invasive Bladder Cancer, Bladder Cancer (BC), Transurethral Resection of Bladdertumors, Transurethral Resection of the Bladder, Non-Muscle Invasive Bladder Carcinoma
Interventions
HISA
Device
Lead sponsor
CAMC Health System
Other
Eligibility
18 Years to 89 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 16, 2026, 1:25 PM EDT
Completed Phase 1Phase 2 Interventional

Phase 1/2 Study of ThermoDox With Approved Hyperthermia in Treatment of Breast Cancer Recurrence at the Chest Wall

NCT00826085
View directory record Official record
Conditions
Breast Cancer
Interventions
ThermoDox in combination with Microwave Hyperthermia (heat)
Drug
Lead sponsor
Imunon
Industry
Eligibility
18 Years and older · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
6
States / cities
San Francisco, California • Newnan, Georgia • Baltimore, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2017 · Synced Sep 16, 2026, 1:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Whole Body Hyperthermia and Major Depression (MDD)

NCT01625546
View directory record Official record
Conditions
Depressive Disorder, Major
Interventions
Whole Body Hyperthermia system
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 9, 2015 · Synced Sep 16, 2026, 1:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Accelerating Post-exercise Muscle Glycogen Resynthesis in Humans: Impact of Combined Nutrient Intake and Intermittent Pneumatic Compression or Heat Therapy

NCT04371237
View directory record Official record
Conditions
Muscle Recovery, Muscle Soreness, Glycogen Depletion
Interventions
Compression sleeve, Heat therapy, Glycogen-depleting exercise session, Nutrient Intake (beverage), Skeletal muscle biopsy
Device · Other · Procedure
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
18 Years to 35 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 9, 2021 · Synced Sep 16, 2026, 1:25 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Study to Evaluate the Safety, Tolerability, and Immunogenicity of Hantaan and Puumala Virus DNA Vaccines

NCT01502345
View directory record Official record
Conditions
Hemorrhagic Fever With Renal Syndrome
Interventions
Vaccine/device combination for prevention of HFRS
Biological
Lead sponsor
U.S. Army Medical Research and Development Command
Federal
Eligibility
18 Years to 49 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 30, 2013 · Synced Sep 16, 2026, 1:25 PM EDT
Terminated Not applicable Interventional Results available

Impact of Fever Prevention in Brain Injured Patients

NCT02996266
View directory record Official record
Conditions
Fever, Ischemic Stroke, Intracerebral Hemorrhage, Subarachnoid Hemorrhage
Interventions
Targeted Temperature Management, Standard Care
Device · Other
Lead sponsor
C. R. Bard
Industry
Eligibility
21 Years to 85 Years
Enrollment
686 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
28
States / cities
Los Angeles, California • Palo Alto, California • Aurora, Colorado + 23 more
Source: ClinicalTrials.gov public record
Updated Sep 20, 2023 · Synced Sep 16, 2026, 1:25 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Whole Body Hyperthermia (WBH) as a Rapid Treatment for Fibromyalgia

NCT02332694
View directory record Official record
Conditions
Fibromyalgia
Interventions
The Whole Body Hyperthermia system uses water-filtered infrared-A (wIRA) heat radiation
Device
Lead sponsor
Charles (Chuck) Raison
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2015
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 26, 2015 · Synced Sep 16, 2026, 1:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Heated Humidification System Breathing Circuit for Maintenance of Body Temperature in Pediatric Patients

NCT03896867
View directory record Official record
Conditions
Temperature Change, Body
Interventions
Anapod™ Humi-Therm Heated Humidification System Breathing Circuit, Bair Hugger™ Warming Blanket
Device
Lead sponsor
University of Minnesota
Other
Eligibility
Up to 18 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 12, 2025 · Synced Sep 16, 2026, 1:25 PM EDT
Completed Early Phase 1 Interventional Results available

Mitomycin C With Hyperthermia and Intravesical Mitomycin C to Treat Recurrent Bladder Cancer

NCT00734994
View directory record Official record
Conditions
Transitional Cell Carcinoma of Bladder, Superficial Bladder Cancer
Interventions
Hyperthermia System, Mitomycin C
Device · Drug
Lead sponsor
Mark Dewhirst
Other
Eligibility
18 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 28, 2015 · Synced Sep 16, 2026, 1:25 PM EDT
Suspended Phase 1Phase 2 Interventional

High Intensity Focused Ultrasound Tumor Treatment for Pancreatic Cancer Pain

NCT00637364
View directory record Official record
Conditions
Pain, Pancreatic Adenocarcinoma, Ductal Adenocarcinoma
Interventions
High intensity focused ultrasound, HIFU
Procedure
Lead sponsor
CMED HIFU Development Corporation
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 12, 2009 · Synced Sep 16, 2026, 1:25 PM EDT
Completed Not applicable Interventional

ECM and Monitoring w/ Alio Smart Patch in Cancer Pts Receiving Chemotherapy

NCT06657183
View directory record Official record
Conditions
Febrile Neutropenia
Interventions
Alio Smart Patch™
Device
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 16, 2026, 1:25 PM EDT
Completed Phase 1 Interventional

Ultrasound in Treating Patients With Prostate Cancer Confined to the Prostate

NCT00030290
View directory record Official record
Conditions
Prostate Cancer
Interventions
high-intensity focused ultrasound ablation
Procedure
Lead sponsor
Focus Surgery
Industry
Eligibility
40 Years to 80 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 9, 2013 · Synced Sep 16, 2026, 1:25 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Phase 2a Immunogenicity Study of Hantaan/Puumala Virus DNA Vaccine for Prevention of Hemorrhagic Fever

NCT02116205
View directory record Official record
Conditions
Hemorrhagic Fever With Renal Syndrome
Interventions
HTNV/PUUV DNA vaccine, Placebo, TriGrid Delivery System (TDS)
Biological · Device
Lead sponsor
U.S. Army Medical Research and Development Command
Federal
Eligibility
18 Years to 49 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 11, 2021 · Synced Sep 16, 2026, 1:25 PM EDT
Completed Phase 2 Interventional Results available

Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer

NCT00445965
View directory record Official record
Conditions
Brain and Central Nervous System Tumors, Intraocular Melanoma, Lung Cancer, Melanoma (Skin), Metastatic Cancer, Neuroblastoma, Ovarian Cancer, Retinoblastoma, Sarcoma, Small Intestine Cancer
Interventions
DNA analysis, immunologic technique, pharmacological study, iodine I 131 monoclonal antibody 3F8, 131I-3F8
Genetic · Other · Radiation
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Not listed
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 3, 2024 · Synced Sep 16, 2026, 1:25 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Xpert® Hemorrhagic Fever on the GeneXpert® Edge X System

NCT07370454
View directory record Official record
Conditions
Hemorrhagic Fever
Interventions
Xpert Hemorrhagic Fever test
Diagnostic Test
Lead sponsor
Cepheid
Industry
Eligibility
14 Years and older
Enrollment
408 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Frederick, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Sep 16, 2026, 1:25 PM EDT
Completed Not applicable Interventional

Post Market Clinical Protocol - Xtremity Polymer Prosthetic Socket System

NCT05190354
View directory record Official record
Conditions
Amputation, Prosthesis User
Interventions
Xtremity Polymer Prosthetic Socket
Device
Lead sponsor
Medical Creations, Inc.
Industry
Eligibility
19 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Aug 23, 2022 · Synced Sep 16, 2026, 1:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness, Safety and Ease of Application of Excel Cryo Cooling Collar to Rapidly Reduce Core Brain Temperature

NCT02703675
View directory record Official record
Conditions
Stroke
Interventions
Excel Cryo Cooling Collar
Device
Lead sponsor
Michel Torbey
Other
Eligibility
18 Years to 60 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 1, 2018 · Synced Sep 16, 2026, 1:25 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Xpert Hemorrhagic Fever on Edge X in Trained and Untrained Users

NCT07591740
View directory record Official record
Conditions
Hemorrhagic Fever
Interventions
Xpert Hemorrhagic Fever test
Diagnostic Test
Lead sponsor
Cepheid
Industry
Eligibility
14 Years and older
Enrollment
725 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 16, 2026, 1:25 PM EDT