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Showing 1–16 of 16 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Hypothermic circulatory arrest Clear all
Completed Not applicable Interventional Results available

Heated Humidified Breathing Circuit Rewarming in Hypothermic Post Cardiopulmonary Bypass Patients.

NCT03697122
View directory record Official record
Conditions
Hypothermia, Rewarming
Interventions
Heated Humidified Breathing Circuit and Forced Air Blanket
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 14, 2020 · Synced Sep 24, 2026, 3:50 AM EDT
Completed No phase listed Observational

Aprotinin Use and Renal Outcome in Hypothermic Bypass and Circulatory Arrest for Surgical Repair of Thoracic Aorta.

NCT00405093
View directory record Official record
Conditions
Circulatory Arrest
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
Not listed
Enrollment
1,250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 18, 2017 · Synced Sep 24, 2026, 3:50 AM EDT
Completed No phase listed Observational

Near-Infrared Spectroscopy Comparison Study

NCT01352260
View directory record Official record
Conditions
Total Aortic Arch Replacement
Interventions
Not listed
Lead sponsor
Nonin Medical, Inc
Industry
Eligibility
18 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 20, 2012 · Synced Sep 24, 2026, 3:50 AM EDT
Recruiting Not applicable Interventional

Retrograde Versus Antegrade Perfusion in Low-Moderate Hypothermia for Aortic Arch Surgery

NCT06986967
View directory record Official record
Conditions
Brain Function, Hemiarch Cardiac Procedure
Interventions
Antegrade Perfusion, Retrograde Perfusion
Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 24, 2026, 3:50 AM EDT
Completed No phase listed Observational

Near Infrared Spectroscopy (NIRS)

NCT01429324
View directory record Official record
Conditions
Aortic Arch Surgery
Interventions
Not listed
Lead sponsor
Nonin Medical, Inc
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 20, 2012 · Synced Sep 24, 2026, 3:50 AM EDT
Completed Not applicable Interventional Results available

Comparing the Effectiveness of a Mitral Valve Repair Procedure in Combination With Coronary Artery Bypass Grafting (CABG) Versus CABG Alone in People With Moderate Ischemic Mitral Regurgitation

NCT00806988
View directory record Official record
Conditions
Mitral Valve Insufficiency, Coronary Artery Disease
Interventions
Mitral Valve Repair, CABG
Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
301 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
19
States / cities
Los Angeles, California • Atlanta, Georgia • Marietta, Georgia + 16 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2017 · Synced Sep 24, 2026, 3:50 AM EDT
Completed Not applicable Interventional

Neurologic Injury Following Aortic Arch Replacement

NCT02750423
View directory record Official record
Conditions
Aortic Arch Replacement, Hemi Arch Replacement
Interventions
DHCA+RCP, MHCA + SACP
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 29, 2018 · Synced Sep 24, 2026, 3:50 AM EDT
Completed No phase listed Observational

Evaluating Erythropoietin as an Indicator for Possible Kidney Injury After Cardiac Surgery

NCT01393418
View directory record Official record
Conditions
Erythropoietin, Acute Kidney Injury, Renal Biomarker
Interventions
Cardiac Surgery
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 14, 2016 · Synced Sep 24, 2026, 3:50 AM EDT
Completed Not applicable Interventional

Cognitive Effects of Body Temperature During Hypothermic Circulatory Arrest

NCT02834065
View directory record Official record
Conditions
Cognition Disorders
Interventions
Cardiopulmonary bypass machine
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
4
States / cities
Atlanta, Georgia • Durham, North Carolina • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 23, 2023 · Synced Sep 24, 2026, 3:50 AM EDT
Active, not recruiting Not applicable Interventional

PERSEVERE- A Trial to Evaluate AMDS in Acute DeBakey Type I Dissection

NCT05174767
View directory record Official record
Conditions
Acute Aortic Dissection
Interventions
AMDS
Device
Lead sponsor
Artivion Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
25
States / cities
Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 20 more
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Sep 24, 2026, 3:50 AM EDT
Terminated Not applicable Interventional

Therapeutic Hypothermia After the Return of Spontaneous Circulation

NCT01617291
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Induced therapeutic hypothermia
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2014 · Synced Sep 24, 2026, 3:50 AM EDT
Recruiting Not applicable Interventional

Comparing Hypothermic Temperatures During Hemiarch Surgery

NCT02860364
View directory record Official record
Conditions
Thoracic Aortic Disease
Interventions
Hypothermic circulatory arrest
Procedure
Lead sponsor
Ottawa Heart Institute Research Corporation
Other
Eligibility
18 Years and older
Enrollment
282 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2030
U.S. locations
3
States / cities
Boston, Massachusetts • Ridgewood, New Jersey • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Sep 24, 2026, 3:50 AM EDT
Completed No phase listed Observational

Intestinal Ischemia as a Stimulus for Systemic Inflammatory Response After Cardiac Arrest

NCT01944605
View directory record Official record
Conditions
Cardiac Arrest, Reperfusion Injury
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Sep 24, 2026, 3:50 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Washington Study of Hemofiltration After Out-of-Hospital Cardiac Arrest

NCT01509040
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Standard Care, Low Volume Hemofiltration, High Volume Hemofiltration
Other · Device
Lead sponsor
University of Washington
Other
Eligibility
65 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 8, 2016 · Synced Sep 24, 2026, 3:50 AM EDT
Terminated Phase 1 Interventional

Cold Heart Study: A Randomized Pilot Trial of Surfactant Therapy

NCT04181255
View directory record Official record
Conditions
Congenital Heart Disease, Hypoplastic Left Heart Syndrome
Interventions
Curosurf, Sham
Drug
Lead sponsor
University of Michigan
Other
Eligibility
1 Day to 12 Weeks
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 12, 2023 · Synced Sep 24, 2026, 3:50 AM EDT
Completed Phase 1 Interventional

FEIBA and Use of Blood Products in Cardiac Surgery

NCT02577614
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
FEIBA, Normal Saline
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 100 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 13, 2020 · Synced Sep 24, 2026, 3:50 AM EDT