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Showing 1–24 of 36 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers

The Valve of Hyaluronic Binding Selection (PICSI) in Improving IVF Outcome

NCT01916213
Conditions
Infertility
Interventions
PICSI
Procedure
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 42 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
New York, New York
Conditions
Infertility, Infertility, Male
Interventions
Laser-assisted intracytoplasmic sperm injection
Procedure
Lead sponsor
Shady Grove Fertility Reproductive Science Center
Other
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004
U.S. locations
1
States / cities
Rockville, Maryland
Conditions
Infertility
Interventions
INVOcell
Device
Lead sponsor
INVO Bioscience, Inc.
Industry
Eligibility
18 Years to 37 Years · Female only
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
4
States / cities
Greenville, South Carolina • West Columbia, South Carolina • San Antonio, Texas + 1 more
Conditions
Infertility
Interventions
ICSI
Other
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
7 participants
Timeline
2018 – 2021
U.S. locations
1
States / cities
Basking Ridge, New Jersey
Conditions
Infertility, Recurrent Pregnancy Loss
Interventions
Microfluidics chamber, Density Gradient Centrifugation
Device · Other
Lead sponsor
Lawrence Engmann
Other
Eligibility
18 Years to 42 Years · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Farmington, Connecticut
Recruiting Not applicable Interventional Accepts healthy volunteers

HELIOS Advanced: Human Oocyte Illumination to Enhance Development

NCT07425080
Conditions
IVF Outcomes
Interventions
Photobiomodulation
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 48 Years · Female only
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Conditions
Infertility, Diminished Ovarian Reserve, IVF
Interventions
Timing of injectable gonadotropins
Procedure
Lead sponsor
Northwell Health
Other
Eligibility
20 Years to 45 Years · Female only
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Manhasset, New York
Terminated Not applicable Interventional Results available

Randomized Trial Comparing EmbryoScope With EmbryoScope+.

NCT03522350
Conditions
Infertility
Interventions
EmbryoScope+
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Conditions
Infertility, Azoospermia
Interventions
Use of IntelliWell to identify and localize sperm for ICSI
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Infertility
Interventions
INVOcell
Device
Lead sponsor
INVO Bioscience, Inc.
Industry
Eligibility
18 Years to 42 Years · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Homewood, Alabama
Conditions
Infertility
Interventions
Zona Pellucida-Bound Sperm Selection for ICSI, Routine Embryologist Selected Sperm
Other
Lead sponsor
IVI America
Other
Eligibility
18 Years to 41 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Francisco, California
Active, not recruiting Phase 4 Interventional

GnRH for Luteal Support in IVF/ICSI/FET Cycles

NCT02357654
Conditions
Infertility
Interventions
GnRH, placebo
Drug
Lead sponsor
University Reproductive Associates
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
1
States / cities
Hasbrouck Heights, New Jersey
Conditions
Infertility, Pregnancy Outcome, Live Birth, In Vitro Fertilization
Interventions
10% SSS embryo culture medium protein supplementation, 0.5% HSA embryo culture medium protein supplementation
Other
Lead sponsor
Texas Health Resources
Other
Eligibility
20 Years to 40 Years · Female only
Enrollment
538 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
2
States / cities
Dallas, Texas • Plano, Texas
Conditions
Male Factor Infertility
Interventions
PICSI dish
Device
Lead sponsor
Biocoat
Industry
Eligibility
18 Years to 40 Years
Enrollment
801 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
9
States / cities
Laguna Hills, California • San Ramon, California • Atlanta, Georgia + 5 more
Not listed Not applicable Interventional Accepts healthy volunteers

Automated Intracytoplasmic Sperm Injection (ICSIA)

NCT05633316
Conditions
Infertility, Female
Interventions
Investigational device named ICSIA, Manual ICSI
Device
Lead sponsor
Overture Life
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Not yet recruiting Not applicable Interventional

Intra-ovarian CAPA-IVM vs Standard IVM

NCT07858435
Conditions
Infertility (IVF Patients), Infertility, Infertility Female
Interventions
CAPA-IVM, In-House CAPA-IVM Pre-Maturation Medium, Minimal-Stimulation OS-IVF
Procedure · Device
Lead sponsor
New Hope Fertility Center
Other
Eligibility
18 Years to 38 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Infertility
Interventions
gamete treatment
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
21 Years to 89 Years
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Male Infertility, Azoospermia
Interventions
BAIBYS Sperm selection, Intra cytoplasmatic sperm injection, Conventional manual sperm selection
Device · Procedure
Lead sponsor
BAIBYS Fertility
Industry
Eligibility
21 Years to 42 Years
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Stamford, Connecticut
Completed Not applicable Interventional

Egg Freezing Pilot Study

NCT00839839
Conditions
Infertility, Egg Freezing
Interventions
Oocyte Vitrification
Procedure
Lead sponsor
University Reproductive Associates
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Hasbrouck Heights, New Jersey
Conditions
Infertility
Interventions
CAPA-IVM System, Serial Unstimulated Transvaginal Oocyte Retrieval, ICSI, Blastocyst Culture, PGT-A, Embryo Vitrification/Accumulation, and Single Euploid Embryo Transfer
Device · Procedure
Lead sponsor
Kevin Doody
Industry
Eligibility
18 Years to 35 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Bedford, Texas
Conditions
Infertility
Interventions
Benchtop Incubator, Box Incubator
Other
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
18 Years to 41 Years · Female only
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Basking Ridge, New Jersey
Not listed No phase listed Observational Accepts healthy volunteers

Overture Metabolomics Non-Selection Study

NCT04878991
Conditions
Infertility
Interventions
Overture Metabolomics Embryo Selection
Diagnostic Test
Lead sponsor
Overture Life
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
410 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Conditions
Infertility
Interventions
Not listed
Lead sponsor
Virginia Center for Reproductive Medicine
Other
Eligibility
21 Years to 42 Years · Female only
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Reston, Virginia
Conditions
Infertility
Interventions
Menopur, Synarel, HCG trigger, Clomiphene citrate, Letrozole
Drug
Lead sponsor
New Hope Fertility Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York