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ClinicalTrials.gov public records Last synced Oct 22, 2026, 11:23 PM EDT

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Showing 361–384 of 8,258 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: IMPROVED Clear all
Completed Not applicable Interventional Results available

HIV+ Substance Users Released From Jail

NCT03834779
View directory record Official record
Conditions
HIV/AIDS, Substance Use Disorders
Interventions
DOORS-CHW Intervention
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Oct 22, 2026, 11:23 PM EDT
Recruiting Phase 1 Interventional

CD19-CD22-Bispecific Chimeric Antigen Receptor (CAR) T Cell Therapy for Pediatric Patients With Acute Lymphoblastic Leukemia

NCT06777979
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia, Recurrent Acute Lymphoblastic Leukemia, Recurrent B Acute Lymphoblastic Leukemia
Interventions
Fludarabine, Cyclophosphamide, Mesna, CD19-CD22 CAR T cell infusion
Drug · Device
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
Up to 21 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 22, 2026, 11:23 PM EDT
Completed Not applicable Interventional Results available

Optimizing Veteran-Centered Prostate Cancer Survivorship Care

NCT01900561
View directory record Official record
Conditions
Prostate Cancer
Interventions
Interactive Voice Response Symptom Management, Tailored Newsletters
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 80 Years · Male only
Enrollment
556 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
4
States / cities
Ann Arbor, Michigan • St Louis, Missouri • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated May 7, 2019 · Synced Oct 22, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Interventions to Improve the HIV PrEP Cascade Among Methamphetamine Users

NCT03584282
View directory record Official record
Conditions
HIV/AIDS, Adherence, Medication, Drug Use
Interventions
Text Messaging, Peer Navigation
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Oct 22, 2026, 11:23 PM EDT
Enrolling by invitation Not applicable Interventional

TMS - Intracranial Electrodes

NCT03702127
View directory record Official record
Conditions
Epilepsy Intractable
Interventions
Transcranial magnetic stimulation
Device
Lead sponsor
Aaron Boes
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Oct 22, 2026, 11:23 PM EDT
Terminated Phase 1 Interventional

Gemcitabine and Docetaxel With Radiation in Adults With Soft Tissue Sarcoma of the Extremities

NCT04037527
View directory record Official record
Conditions
Soft Tissue Sarcoma
Interventions
Gemcitabine, Docetaxel, Radiation, Surgical Resection, Blood draws
Drug · Radiation · Procedure + 1 more
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 22, 2026, 11:23 PM EDT
Completed Not applicable Interventional Results available

Mobile Mindfulness to Improve Psychological Distress After Critical Illness

NCT02701361
View directory record Official record
Conditions
Psychological Distress, Depression, Anxiety, Post-traumatic Stress Disorder, Informal Caregivers, Family Members
Interventions
mobile mindfulness, standard mindfulness, education
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Durham, North Carolina • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 7, 2018 · Synced Oct 22, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adjunctive Team Enhanced Intervention to Improve Suicide Prevention Evidence-Based Practices in Primary Care

NCT04606173
View directory record Official record
Conditions
Suicide Prevention
Interventions
Team Education for Adopting Changes in Healthcare (TEACH)
Other
Lead sponsor
Syracuse VA Medical Center
Federal
Eligibility
Not listed
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 24, 2023 · Synced Oct 22, 2026, 11:23 PM EDT
Enrolling by invitation Not applicable Interventional

Evaluating the Feasibility and Preliminary Effects of BE+

NCT07214441
View directory record Official record
Conditions
Lung Cancer (Non-Small Cell), Self-management Behavior, Physical Activity, Stress, Quality of Life, Resistance Training
Interventions
Breathe Easier+
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Oct 22, 2026, 11:23 PM EDT
Completed Not applicable Interventional Results available

Does Radiofrequency Ablation of the Articular Nerves of the Knee Prior to Total Knee Replacement Improve Pain Outcomes

NCT02746874
View directory record Official record
Conditions
Arthroplasty, Replacement, Knee
Interventions
Radiofrequency Ablation (RFA), Simulated Radiofrequency Ablation (RFA)
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
30 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Oct 22, 2026, 11:23 PM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

Effects of Magnetic Therapy and Seawater Combined in Decreasing Intraocular Presion.

NCT02300818
View directory record Official record
Conditions
Primary Open Angle Glaucoma, Hypertension Ocular
Interventions
Pulsed Electromagnetic Field Therapy, Seawater eyedrops
Device · Drug
Lead sponsor
American Society Of Thermalism And Climatology Inc
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 23, 2015 · Synced Oct 22, 2026, 11:23 PM EDT
Recruiting Not applicable Interventional

Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment

NCT03891160
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
3D model of heart
Other
Lead sponsor
Columbia University
Other
Eligibility
Not listed
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
5
States / cities
Gainesville, Florida • Atlanta, Georgia • Chicago, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 10, 2025 · Synced Oct 22, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Outcomes in Children With Pre-operative Residual Hearing

NCT03379870
View directory record Official record
Conditions
High Frequency Sensorineural Hearing Impairment, Hearing Disorders in Children
Interventions
Electric Acoustic Speech Processor: Electric-acoustic stimulation fitting, Electric Acoustic Speech Processor: Full-electric stimulation fitting
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
60 Months to 215 Months
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 22, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Healthy Start: Family Childcare Providers and Parents

NCT06978270
View directory record Official record
Conditions
Child Obesity, Nutrition, Healthy
Interventions
Healthy Eating: Provider and Parent Components, Healthy Start: Reading Readiness Childcare Proiver and Parent Materials
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 22, 2026, 11:23 PM EDT
Completed Not applicable Interventional

Mindfulness Meditation and Insomnia in Alzheimer Disease Caregivers

NCT03538574
View directory record Official record
Conditions
Insomnia Chronic
Interventions
CBT-I, MAP-I
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
45 Years to 95 Years
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 4, 2022 · Synced Oct 22, 2026, 11:23 PM EDT
Completed Phase 2 Interventional

Efficacy and Safety of GRT9906 Tablets Compared to Placebo in Patients With Fibromyalgia

NCT03783910
View directory record Official record
Conditions
Primary Fibromyalgia
Interventions
GRT9906, Placebo
Drug
Lead sponsor
Grünenthal GmbH
Industry
Eligibility
18 Years to 75 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
6
States / cities
DeLand, Florida • Charlotte, North Carolina • Medford, Oregon + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 21, 2018 · Synced Oct 22, 2026, 11:23 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Lyme Test Indication Combinations (LyTIC) Study

NCT03201042
View directory record Official record
Conditions
Lyme Disease
Interventions
PCR based assay, Serology based assay, Tcell based assay
Diagnostic Test
Lead sponsor
Oxford Immunotec
Industry
Eligibility
5 Years and older
Enrollment
410 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
60
States / cities
Redding, California • New London, Connecticut • Norwalk, Connecticut + 53 more
Source: ClinicalTrials.gov public record
Updated Dec 13, 2018 · Synced Oct 22, 2026, 11:23 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

The January Application NUtritional Study (JANUS)

NCT03604250
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Lifestyle plus prebiotic supplement
Dietary Supplement
Lead sponsor
January, Inc.
Industry
Eligibility
30 Years to 60 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Menlo Park, California
Source: ClinicalTrials.gov public record
Updated Jun 9, 2020 · Synced Oct 22, 2026, 11:23 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mastery Learning in Communication Skills

NCT05979090
View directory record Official record
Conditions
Communication Research, Communication, Personal, Burnout, Professional
Interventions
Mastery learning in communication skills
Behavioral
Lead sponsor
Heather Ballard
Other
Eligibility
20 Years to 60 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 22, 2026, 11:23 PM EDT
Completed Phase 2 Interventional

Blueberry Consumption Improves Vascular Function and Lowers Blood Pressure in Postmenopausal Women With Pre- and Stage 1-hypertension

NCT01686282
View directory record Official record
Conditions
Blood Pressure
Interventions
Freeze-dried Blueberry Powder, Placebo
Dietary Supplement
Lead sponsor
Florida State University
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Jan 14, 2015 · Synced Oct 22, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Breathing Room Intervention to Achieve Better Lung Health in Older Adults

NCT05330780
View directory record Official record
Conditions
Breathing, Aging
Interventions
Breathing Room
Other
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
45 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 1, 2023 · Synced Oct 22, 2026, 11:23 PM EDT
Completed Not applicable Interventional Results available

Perioperative Aminophylline to Improve Early Kidney Function After a Kidney Transplant

NCT01759862
View directory record Official record
Conditions
Function of Renal Transplant
Interventions
Aminophylline, Theophylline drug levels, Placebo
Drug · Other
Lead sponsor
Stanford University
Other
Eligibility
1 Year to 21 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2019 · Synced Oct 22, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Leadership, Engagement, and Youth Action Program With Mindfulness (LEAP)

NCT06227403
View directory record Official record
Conditions
Adolescent Behavior, Mental Health Wellness 1
Interventions
Leadership, Engagement, and youth Action Program with Mindfulness, EnvisionIT
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
14 Years to 18 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
Chicago, Illinois • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Oct 22, 2026, 11:23 PM EDT
Completed Not applicable Interventional

Effective Management of Emotional Response to Generate Well-Being Post-HF Exacerbation

NCT03043261
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Williams LifeSkills
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 7, 2018 · Synced Oct 22, 2026, 11:23 PM EDT