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ClinicalTrials.gov public records Last synced Oct 30, 2026, 10:10 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1129–1152 of 8,267 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: IMPROVED Clear all
Completed Not applicable Interventional

ARUA-ALZ - Connecting Audio and Radio SensingmSystems to Improve Care at Home for ADRD

NCT06170528
View directory record Official record
Conditions
Alzheimer Disease, Caregiver Burden
Interventions
AURA_ALZ
Device
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 110 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 23, 2024 · Synced Oct 30, 2026, 10:10 AM EDT
Completed Phase 1 Interventional

Mobility Training to Improve Motor Behavior in Toddlers With or at Risk for Cerebral Palsy: A Pilot Study

NCT01253083
View directory record Official record
Conditions
Developmental Delay, Cerebral Palsy
Interventions
mobility training with dynamic body weight support
Behavioral
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
12 Months to 36 Months
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Oct 30, 2026, 10:10 AM EDT
Completed Not applicable Interventional

Osteopathic Manual Treatment Parkinson's Disease and Truncal Dystonia

NCT03307161
View directory record Official record
Conditions
Parkinson Disease, Dystonia, Autonomic Dysreflexia
Interventions
osteopathic manual therapy
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Sep 23, 2021 · Synced Oct 30, 2026, 10:10 AM EDT
Withdrawn Not applicable Interventional

LED Light Therapy to Improve Cognitive & Psychosocial Function in TBI-PTSD Veterans

NCT02356861
View directory record Official record
Conditions
Traumatic Brain Injury (TBI), Post-traumatic Stress Disorder (PTSD)
Interventions
Photomedex Sham Helmet with Red/Near-Infrared Light-Emitting Diodes (LEDs) that are not turned on
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Oct 30, 2026, 10:10 AM EDT
Not listed Phase 1 Interventional

Levetiracetam (Keppra) to Improve Chronic Aphasia in Post-stroke Patients.

NCT00227461
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Wait first, then levetiracetam, Levetiracetam first, then wait
Drug
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2021
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 17, 2021 · Synced Oct 30, 2026, 10:10 AM EDT
Completed Not applicable Interventional Results available

Relative Patient Benefits of a Hospital-PCMH Collaboration Within an ACO to Improve Care Transitions

NCT02130570
View directory record Official record
Conditions
Adverse Events, Readmissions, Patient Engagement
Interventions
Multi-Model Intensive Discharge Intervention
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
1,679 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 20, 2019 · Synced Oct 30, 2026, 10:10 AM EDT
Completed Phase 2 Interventional Results available

An Adaptive Algorithm-Based Approach to Treatment for Adolescent Depression

NCT03222570
View directory record Official record
Conditions
Depressive Disorder
Interventions
Interpersonal Psychotherapy for Depressed Adolescents, Selective Serotonin Reuptake Inhibitor, Usual Care
Behavioral · Drug · Other
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years to 18 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Oct 30, 2026, 10:10 AM EDT
Completed Not applicable Interventional

Addressing Neuromuscular Deficits for Improved Outcomes in Ankle Rehabilitation

NCT03663361
View directory record Official record
Conditions
Ankle Sprains
Interventions
SMART Intervention, Standard of Care Intervention
Other
Lead sponsor
Phillip Gribble
Other
Eligibility
18 Years to 44 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
2
States / cities
Lexington, Kentucky • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 30, 2026, 10:10 AM EDT
Terminated Not applicable Interventional

Does Wearing Tetra-Grip Improve Arm Function in Children Diagnosed With Neonatal Brachial Plexus Palsy?

NCT03647761
View directory record Official record
Conditions
Neonatal Brachial Plexus Palsy
Interventions
Tetra-grip
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
3 Years to 7 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 5, 2022 · Synced Oct 30, 2026, 10:10 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Morning Bright Light to Improve Sleep Quality in Veterans

NCT03578003
View directory record Official record
Conditions
Brain Injuries, Traumatic, Post-traumatic Stress Disorder
Interventions
Morning Bright Light Therapy
Other
Lead sponsor
Portland VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
Portand, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 14, 2025 · Synced Oct 30, 2026, 10:10 AM EDT
Active, not recruiting Not applicable Interventional

TraNsvenous TrIcuspid Valve ReplacemenT With LuX-Valve Plus System (TRINITY-US)

NCT06568003
View directory record Official record
Conditions
Tricuspid Regurgitation (TR)
Interventions
Transcatheter Tricuspid Valve Intervention
Device
Lead sponsor
Jenscare Innovation Inc.
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
3
States / cities
Los Angeles, California • Detroit, Michigan • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 30, 2026, 10:10 AM EDT
Completed Not applicable Interventional Results available

Chronic Kidney Disease Clinical Decision Support

NCT03890588
View directory record Official record
Conditions
Chronic Kidney Diseases, Hypertension, Diabetes
Interventions
CKD enhanced clinical decision support
Other
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
6,295 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 1, 2022 · Synced Oct 30, 2026, 10:10 AM EDT
Completed Not applicable Interventional Results available

Gaming for Autism to Mold Executive Skills Project

NCT02361762
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
Computerized executive control training
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
7 Years to 11 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 28, 2021 · Synced Oct 30, 2026, 10:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healthy Aging Resources to Thrive (HART)

NCT03739762
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
i-STAND, Healthy Living control
Behavioral · Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
60 Years to 89 Years
Enrollment
283 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 25, 2024 · Synced Oct 30, 2026, 10:10 AM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Study to Improve Scientific Understanding of the Cardiovascular Actions of Cocaine

NCT00338546
View directory record Official record
Conditions
Cocaine Induced Sympathoexciation and Vasoconstriction
Interventions
Cocaine hydrochloride, Dexmedetomidine, Microneurography, Laser doppler velocimetry
Drug · Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 16, 2019 · Synced Oct 30, 2026, 10:10 AM EDT
Recruiting Not applicable Interventional

Assessment of a Method to Improve Cochlear Implant Users' Speech Perception in Noisy Environments While Maintaining Their Ability to Determine Where a Sound Originates From

NCT07323862
View directory record Official record
Conditions
Cochlear Implant Users
Interventions
Modifying audio input for cochlear implant processor
Device
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Champaign, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 30, 2026, 10:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

e-Motivación: Developing and Pilot Testing an App to Improve Latinos' Screening Colonoscopy Rates

NCT04987788
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Motívate, Video link
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
Not listed
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 18, 2024 · Synced Oct 30, 2026, 10:10 AM EDT
Completed Phase 4 Interventional

Study of the Effectiveness of Cevimeline on Oral Health in Patients With Radiation Induced Xerostomia

NCT00466388
View directory record Official record
Conditions
Xerostomia
Interventions
Cevimeline
Drug
Lead sponsor
American Academy of Otolaryngology-Head and Neck Surgery Foundation
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
7
States / cities
Colorado Springs, Colorado • Urbana, Illinois • Kansas City, Kansas + 4 more
Source: ClinicalTrials.gov public record
Updated May 22, 2014 · Synced Oct 30, 2026, 10:10 AM EDT
Completed Not applicable Interventional

Evaluating Strategies to Improve Guideline Directed Medical Therapy: The GDMT Research, Education & Assist Trial for Heart Failure Care

NCT05990296
View directory record Official record
Conditions
Heart Failure, Heart Failure With Reduced Ejection Fraction
Interventions
Multiprong CDS with referral to pharmacist co-management, Multiprong CDS with GDMT order set, Focused education
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
4,306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 19, 2025 · Synced Oct 30, 2026, 10:10 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Feasibility Study of Personalized Trials to Improve Sleep Quality

NCT05349188
View directory record Official record
Conditions
Sleep Disturbance
Interventions
Melatonin 3 mg, Melatonin 0.5 mg, Cellulose placebo pill
Dietary Supplement · Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Oct 30, 2026, 10:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Peer-Delivered Episodic Future Thinking for Returning Citizens

NCT06119503
View directory record Official record
Conditions
Behavior, Health
Interventions
Elongating Time HOrizons for Reentry (ETHoR), Standardized Episodic Thinking (SET)
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Oct 30, 2026, 10:10 AM EDT
Completed Not applicable Interventional

Effects of Flourish HEC on Localized Provoked Vulvodynia

NCT05478746
View directory record Official record
Conditions
Vulvodynia, Vestibulodynia, Vulvar Diseases, Vulvar Vestibulitis, Vulvar Pain
Interventions
BioNourish, a component of the Flourish HEC kit, Control - no intervention
Device · Other
Lead sponsor
Vaginal Biome Science
Other
Eligibility
18 Years to 52 Years · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Virginia Beach, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Oct 30, 2026, 10:10 AM EDT
Completed Not applicable Interventional Results available

TAKE Steps: Motivational Interviewing to Prevent STIs

NCT05215262
View directory record Official record
Conditions
Self Efficacy, HIV Prevention, STI Prevention
Interventions
Treat Act Know Engage (T.A.K.E.) Steps, Standard or Care
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
13 Years to 19 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
5
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Oct 30, 2026, 10:10 AM EDT
Recruiting Phase 2 Interventional

Using Reiki Therapy to Improve Symptoms Associated With Brachytherapy in Patients With Gynecological Malignancies

NCT05979610
View directory record Official record
Conditions
Gynecologic Neoplasm, Brachytherapy, Therapeutic Touch, Endometrial Cancer, Cervical Cancer, Vaginal Cancer, Vulvar Cancer
Interventions
Reiki therapy
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 30, 2026, 10:10 AM EDT