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ClinicalTrials.gov public records Last synced Oct 21, 2026, 10:50 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 74 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: IMT Clear all
Withdrawn Not applicable Interventional

Preoperative Optimization to Improve Functional Status

NCT04566172
View directory record Official record
Conditions
Pulmonary Atelectasis, Pneumonia, Ventilator-Associated
Interventions
Inspiratory Muscle Training (IMT)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
65 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Oct 21, 2026, 10:50 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Goal-Directed Resilience Training to Mitigate Chronic Pain in Former Football Players

NCT04107519
View directory record Official record
Conditions
Chronic Pain
Interventions
Goal-Directed Resilience Training
Behavioral
Lead sponsor
Morehouse School of Medicine
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 24, 2022 · Synced Oct 21, 2026, 10:50 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Antiretrovirals and Rate of Progression in Carotid Artery Intima-medial Thickness in HIV

NCT00575939
View directory record Official record
Conditions
HIV Infections, Atherosclerosis
Interventions
Not listed
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 19, 2014 · Synced Oct 21, 2026, 10:50 AM EDT
Not yet recruiting Not applicable Interventional

Inspiratory Muscle Training in Hospitalized Patients With Heart Failure Awaiting Advanced Therapies

NCT07862738
View directory record Official record
Conditions
Heart Failure, Heart Failure New York Heart Association Class III, Heart Failure New York Heart Association Class IV
Interventions
POWERbreathe KH2, Usual Care
Device · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 21, 2026, 10:50 AM EDT
Withdrawn Not applicable Interventional

The Impact of Aerobic Interval and Inspiratory Muscle Training On Patient Reported Outcome Scores In Individuals With Chronic Constipation

NCT05321953
View directory record Official record
Conditions
Constipation, Constipation by Outlet Obstruction, Constipation-predominant Irritable Bowel Syndrome, Constipation - Functional
Interventions
Standard Physical Therapy Care, Aerobic and Inspiratory Muscle Training
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated May 12, 2023 · Synced Oct 21, 2026, 10:50 AM EDT
Completed Not applicable Interventional

Inspiratory Muscle Training in Obese Breast Cancer Survivors

NCT05193149
View directory record Official record
Conditions
Cancer Survivors, Obesity, Breast Cancer
Interventions
Inspiratory muscle training, Exercise training
Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 21, 2026, 10:50 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effect of Aged Garlic Extract on Atherosclerosis

NCT01534910
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
aged garlic extract, placebo
Drug
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
40 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Oct 21, 2026, 10:50 AM EDT
Completed Not applicable Interventional Results available

Effects of a Walking Program and Inspiratory Muscle Training in Individuals With Chronic Heart Failure

NCT01560871
View directory record Official record
Conditions
Heart Failure NYHA Class II, Heart Failure NYHA Class III
Interventions
High-intensity IMT plus walking, Low-intensity IMT plus walking
Behavioral
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 90 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 21, 2026, 10:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Inspiratory Muscle Training in Postmenopausal Women

NCT06459674
View directory record Official record
Conditions
Postmenopausal Symptoms, Aging, Obesity
Interventions
PrO2 Fit (IMT Trainer)
Device
Lead sponsor
Indiana University
Other
Eligibility
50 Years to 75 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 21, 2026, 10:50 AM EDT
Completed No phase listed Observational

Mucosal Versus Fecal Microbiota in FMT

NCT02133651
View directory record Official record
Conditions
Clostridium Difficile
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 9, 2015 · Synced Oct 21, 2026, 10:50 AM EDT
Not listed Not applicable Interventional

Telehealth and Onsite Maintenance Exercise in Chronic Lung Disease

NCT06304207
View directory record Official record
Conditions
Copd, COPD Exacerbation, COPD Bronchitis, Emphysema or COPD, Chronic Lung Disease, Pulmonary Fibrosis, Interstitial Lung Disease, Bronchiectasis, Chronic Asthma, Chronic Asthmatic Bronchitis
Interventions
Onsite Maintenance Exercise Training, Telehealth Maintenance Exercise
Combination Product
Lead sponsor
MGH Institute of Health Professions
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 1, 2024 · Synced Oct 21, 2026, 10:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diaphragm Structure and Function in Children

NCT06230692
View directory record Official record
Conditions
Respiratory Muscle Training
Interventions
POWERbreathe Plus IMT
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
6 Years to 12 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 21, 2026, 10:50 AM EDT
Completed Phase 2 Interventional Results available

Immune-Modulated Study of Selected Small Molecules (Gefitinib, AZD9291, or Selumetinib + Docetaxel) or a 1st Immune-Mediated Therapy (IMT; Tremelimumab) With a Sequential Switch to a 2nd IMT (MEDI4736) in Patients With Locally Advanced or Metastatic Non-Small-Cell Lung Cancer

NCT02179671
View directory record Official record
Conditions
Locally Advanced or Metastatic Non-Small-Cell Lung Cancer (Stage IIIB-IV)
Interventions
Gefitinib, AZD9291, Selumetinib+Docetaxel, Tremelimumab
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 130 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
10
States / cities
Goodyear, Arizona • Washington D.C., District of Columbia • Augusta, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2019 · Synced Oct 21, 2026, 10:50 AM EDT
Recruiting Not applicable Interventional

Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD

NCT05438732
View directory record Official record
Conditions
Age-Related Macular Degeneration, Geographic Atrophy
Interventions
smaller incision, new generation implantable miniature telescope (SING-IMT)
Device
Lead sponsor
VisionCare, Inc.
Industry
Eligibility
65 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
10
States / cities
Loma Linda, California • Long Beach, California • Sarasota, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 3, 2024 · Synced Oct 21, 2026, 10:50 AM EDT
Completed Not applicable Interventional Results available

Respiratory Muscle Training (RMT) in ALS

NCT04224961
View directory record Official record
Conditions
ALS
Interventions
Respiratory Muscle Training
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Oct 21, 2026, 10:50 AM EDT
Withdrawn Not applicable Interventional

Study of Inspiratory Muscle Training for Patients Undergoing Esophageal Surgery

NCT02843750
View directory record Official record
Conditions
Cancer of Esophagus, Cancer of the Esophagus, Esophageal Cancer, Esophagus Cancer, Esophagus Neoplasm, Neoplasms, Esophageal
Interventions
Inspiratory Muscle Training-Rehabilitation, Questionnaires
Behavioral · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 99 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 15, 2016 · Synced Oct 21, 2026, 10:50 AM EDT
Terminated Not applicable Interventional

Neural Mechanisms of Motor Recovery With Technology Assisted Training

NCT05560867
View directory record Official record
Conditions
Hemiparesis, Stroke Sequelae
Interventions
robot-assisted training
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 26, 2024 · Synced Oct 21, 2026, 10:50 AM EDT
Completed Not applicable Interventional

Inspiratory Muscle Training Post-Liver Transplant

NCT03130608
View directory record Official record
Conditions
Liver Disease Chronic, Muscle Weakness, Respiratory Insufficiency
Interventions
Inspiratory Muscle Training
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 21, 2021 · Synced Oct 21, 2026, 10:50 AM EDT
Completed Phase 2 Interventional

Rebeccamycin Analog in Treating Patients With Metastatic or Locally Recurrent Colorectal Cancer

NCT00005085
View directory record Official record
Conditions
Colorectal Cancer
Interventions
becatecarin
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2000
U.S. locations
3
States / cities
Atlanta, Georgia • The Bronx, New York • Valhalla, New York
Source: ClinicalTrials.gov public record
Updated Feb 11, 2013 · Synced Oct 21, 2026, 10:50 AM EDT
Withdrawn Not applicable Interventional

The General Use of Robots in Stroke Recovery

NCT01726660
View directory record Official record
Conditions
Stroke
Interventions
IMT Robotic Arm therapy
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Oct 21, 2026, 10:50 AM EDT
Completed Not applicable Interventional Results available

A Randomized, Controlled Trial of Inspiratory Muscle Training (IMT)in the ICU and CCU

NCT02003053
View directory record Official record
Conditions
Critically Ill, Respiratory Failure
Interventions
Inspiratory Muscle Trainer
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 90 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 7, 2018 · Synced Oct 21, 2026, 10:50 AM EDT
Withdrawn Phase 1Phase 2 Interventional

Breast Cancer Vaccine in Combination With Pembrolizumab for Treatment of Persistent, Recurrent, or Metastatic Breast Cancer

NCT04418219
View directory record Official record
Conditions
Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma, Prognostic Stage IV Breast Cancer AJCC v8, Recurrent Breast Carcinoma, Refractory Breast Carcinoma
Interventions
Cyclophosphamide, Allogeneic GM-CSF-secreting Breast Cancer Vaccine SV-BR-1-GM, Pembrolizumab, Recombinant Interferon Alpha 2b-like Protein, Questionnaire Administration, Quality of Life Assessment
Drug · Biological · Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Oct 21, 2026, 10:50 AM EDT
Not listed Not applicable Interventional

Inspiratory Muscle Training in COPD

NCT03438019
View directory record Official record
Conditions
COPD
Interventions
PrO2, Threshold Inspiratory Muscle Trainer
Device
Lead sponsor
Miami VA Healthcare System
Federal
Eligibility
40 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 20, 2018 · Synced Oct 21, 2026, 10:50 AM EDT
Completed Phase 3 Interventional

Ventilatory Muscle Training in Stroke

NCT02828943
View directory record Official record
Conditions
Stroke, Pulmonary Ventilation, Exercise Therapy
Interventions
IMT with High Resistance EMT, IMT with Low Resistance EMT
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 17, 2019 · Synced Oct 21, 2026, 10:50 AM EDT