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ClinicalTrials.gov public records Last synced Oct 29, 2026, 9:53 PM EDT

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Showing 505–528 of 1,023 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: INDEPENDENCE Clear all
Recruiting No phase listed Observational

The restor3d Outcomes Registry

NCT07563803
View directory record Official record
Conditions
Joint Replacement, Arthropathy
Interventions
Patient-Specific Orthopedic Implant
Device
Lead sponsor
Restor3D
Industry
Eligibility
18 Years and older
Enrollment
2,250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 27, 2026 · Synced Oct 29, 2026, 9:53 PM EDT
Completed Not applicable Interventional

Surprise Question in End of Life (SeQuEL) Care and the Effect of Prompting Palliative Care Consultation: End-Stage Liver Disease

NCT06400498
View directory record Official record
Conditions
End-Stage Liver Disease
Interventions
Prompted Palliative Care Consult
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Oct 29, 2026, 9:53 PM EDT
Completed Phase 1 Interventional

A Study to Assess the Safety, Tolerability and Anti-tumour Activity of Ascending Doses of Selumetinib in Combination With MEDI4736 and Selumetinib in Combination With MEDI4736 and Tremelimumab in Patients With Advanced Solid Tumours

NCT02586987
View directory record Official record
Conditions
Lung Cancer, Melanoma, Head and Neck Carcinoma, Gastroesophageal Cancer, Breast Cancer, Pancreatic Adenocarcinoma, Colorectal Cancer, Biliary Tract Cancer
Interventions
Selumetinib, MEDI4736, Tremelimumab
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 99 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
6
States / cities
Chicago, Illinois • Boston, Massachusetts • Las Vegas, Nevada + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 18, 2019 · Synced Oct 29, 2026, 9:53 PM EDT
Completed Not applicable Interventional

Flipped Classroom for Weight Management

NCT06622278
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Flipped Classroom
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Oct 29, 2026, 9:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Meditation Intervention on Subconcussive Head Impacts

NCT04225663
View directory record Official record
Conditions
Head Injury Trauma
Interventions
Guided Meditation
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
13 Years to 25 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 7, 2023 · Synced Oct 29, 2026, 9:53 PM EDT
Completed No phase listed Observational

Advance Provision of Postpartum Emergency Contraception and Its Effects on Reproductive Autonomy

NCT05285605
View directory record Official record
Conditions
Contraception, Contraceptive Usage, Reproductive Issues
Interventions
Ulipristal Acetate
Drug
Lead sponsor
Northwestern University
Other
Eligibility
16 Years to 40 Years · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Oct 29, 2026, 9:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prosocial Behavior and Volunteerism to Promote Physical Activity in Older Adults

NCT01528761
View directory record Official record
Conditions
Physical Activity
Interventions
Prosocial Behavior Physical Activity (PBPA), Healthy Aging (HA)
Behavioral · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
55 Years and older
Enrollment
317 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2018 · Synced Oct 29, 2026, 9:53 PM EDT
Completed Not applicable Interventional

Improving Brief Marijuana Interventions With a Behavioral Economic Supplement

NCT02837315
View directory record Official record
Conditions
Marijuana Use
Interventions
Brief Motivational Intervention (BMI), Substance-Free Activity Session (SFAS), Relaxation Session
Behavioral
Lead sponsor
University of Memphis
Other
Eligibility
18 Years and older
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Oct 29, 2026, 9:53 PM EDT
Not yet recruiting Phase 1Phase 2 Interventional

A Study of Catequentinib Hydrochloride (AL3818) in Endometrial, LGSOC, STS or GBM Cancers

NCT07811297
View directory record Official record
Conditions
Endometrial Neoplasms, Ovarian Neoplasms, Soft Tissue Sarcoma (STS), Glioblastoma
Interventions
AL58805, AL3818, Temozolomide (TMZ), CCNU
Drug
Lead sponsor
Advenchen Pharmaceuticals, LLC.
Industry
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 29, 2026, 9:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Fractional Radiofrequency for the Treatment Acne Scarring

NCT03821324
View directory record Official record
Conditions
Acne Scars
Interventions
Venus Viva
Device
Lead sponsor
Venus Concept
Industry
Eligibility
22 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 4, 2023 · Synced Oct 29, 2026, 9:53 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Harm Reduction in HIV Primary Care for PLWH Who Use Drugs

NCT05404750
View directory record Official record
Conditions
Human Immunodeficiency Virus, Substance Use, Stigma, Social
Interventions
Harm Reduction
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
641 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
3
States / cities
Birmingham, Alabama • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 29, 2026, 9:53 PM EDT
Completed Not applicable Interventional Results available

Stage 1 Treatment Development With Homeless Mothers

NCT01193114
View directory record Official record
Conditions
Substance Abuse
Interventions
Ecologically Based Treatment (EBT), Treatment as Usual (TAU)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 1, 2013 · Synced Oct 29, 2026, 9:53 PM EDT
Completed Phase 1 Interventional Results available

An Exploratory Study Investigating Safety, Tolerability and Pharmacokinetics of Ascending Doses of Lu AE04621 in Parkinson Disease Patients

NCT02649608
View directory record Official record
Conditions
Parkinson Disease
Interventions
0.04 mg Lu AE04621, 0.08 mg Lu AE04621, 0.2 mg Lu AE04621, 0.4 mg Lu AE04621, 0.6 mg Lu AE04621, 0.8 mg Lu AE04621, 1.0 mg Lu AE04621, 1.2 mg Lu AE04621
Drug
Lead sponsor
H. Lundbeck A/S
Industry
Eligibility
45 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
4
States / cities
Hallandale, Florida • Orlando, Florida • Chicago, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2021 · Synced Oct 29, 2026, 9:53 PM EDT
Completed Not applicable Interventional

Life Skills Improved in Children With Down Syndrome After Using Assistive Technology

NCT05343468
View directory record Official record
Conditions
Down Syndrome, Adaptive Behavior, Quality of Life
Interventions
The MapHabit System
Device
Lead sponsor
MapHabit, Inc.
Industry
Eligibility
7 Years to 17 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 24, 2023 · Synced Oct 29, 2026, 9:53 PM EDT
Completed Phase 4 Interventional Results available

Study of Insulin Lispro in Participants With Inadequately Controlled Type 2 Diabetes

NCT01215955
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Insulin lispro, Glargine
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 85 Years
Enrollment
1,117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
33
States / cities
Phoenix, Arizona • Concord, California • Fresno, California + 30 more
Source: ClinicalTrials.gov public record
Updated Apr 23, 2014 · Synced Oct 29, 2026, 9:53 PM EDT
Active, not recruiting Not applicable Interventional

Implant for Walking After Stroke

NCT05740540
View directory record Official record
Conditions
Stroke, Hemiplegia, Gait, Hemiplegic
Interventions
IRS-8, IST 12 & IST 16
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 29, 2026, 9:53 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cardiovascular Effects of Grieving

NCT07356635
View directory record Official record
Conditions
Grief, Cardiovascular Health, Emotion
Interventions
Value-affirmation
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 29, 2026, 9:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of the Use of Low Level Laser Therapy to Reduce Acne

NCT01276535
View directory record Official record
Conditions
Acne
Interventions
Erchonia MLS + Erchonia THL
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years to 40 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 11, 2015 · Synced Oct 29, 2026, 9:53 PM EDT
Completed Not applicable Interventional

Impacts of the Positive Youth Development Program for Expectant and Parenting Teens in California

NCT04181034
View directory record Official record
Conditions
Teen Pregnancy Prevention
Interventions
Adolescent Family Life Program Positive Youth Development (PYD) program, Adolescent Family Life Program (AFLP)
Behavioral
Lead sponsor
Mathematica Policy Research, Inc.
Other
Eligibility
14 Years to 18 Years · Female only
Enrollment
1,330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
13
States / cities
Goleta, California • Hayward, California • Kelseyville, California + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 25, 2021 · Synced Oct 29, 2026, 9:53 PM EDT
Recruiting Not applicable Interventional

Concussion Health Improvement Program

NCT06036147
View directory record Official record
Conditions
Concussion, Brain, Brain Injury Traumatic Mild
Interventions
Concussion-focused cognitive behavioral therapy, Parent skills training, Care management
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
11 Years to 18 Years
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 13, 2025 · Synced Oct 29, 2026, 9:53 PM EDT
Completed Phase 2 Interventional

Perioperative Intervention to Improve Post-TKR Support and Function

NCT00566826
View directory record Official record
Conditions
Osteoarthritis, Arthroplasty, Replacement, Knee
Interventions
Patient support sessions, Treatment as usual
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
21 Years and older
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 6, 2023 · Synced Oct 29, 2026, 9:53 PM EDT
Not listed No phase listed Observational

A Study to Evaluate the Performance of a Diagnostic Test in ALS

NCT02759913
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis (ALS)
Interventions
Lumbar puncture
Procedure
Lead sponsor
Iron Horse Diagnostics, Inc.
Industry
Eligibility
21 Years to 80 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 3, 2016 · Synced Oct 29, 2026, 9:53 PM EDT
Completed Not applicable Interventional Results available

Implementing a Skills-Based Caregiver Training Program (Caregivers FIRST): Function QUERI 2.0

NCT05319535
View directory record Official record
Conditions
Cognitive Function, Functional Status
Interventions
Implementation Strategy: Foundational REP, Implementation Strategy: Enhanced REP
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Oct 29, 2026, 9:53 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Neurobiological Similarities of Tinnitus and PTSD

NCT05981391
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Tinnitus
Interventions
resting-state functional MRI, Clinician Administered PTSD Scale for the DSM-5 (CAPS-5), Tympanometry, Tinnitus Assessment, Otoscopy, Pure tone air and bone-conduction, Speech testing, Loudness Discomfort, Quick Speech in Noise Test, Distortion-Product Otoacoustic Emissions (DPOAE)
Diagnostic Test
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Oct 29, 2026, 9:53 PM EDT