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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:04 PM EDT

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Showing 241–264 of 310 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: IOL Clear all
Completed Phase 4 Interventional Accepts healthy volunteers

Time Study for Biometry Measurements With the Lenstar and IntraOcularLens (IOL) Master 500

NCT01550939
View directory record Official record
Conditions
Pseudoaphakia
Interventions
Ophthalmic Biometer
Device
Lead sponsor
Haag Streit USA
Industry
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 1, 2012 · Synced Oct 21, 2026, 5:04 PM EDT
Not listed Phase 2 Interventional

Combination Chemotherapy Followed by Donor Bone Marrow Transplant or Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer or Genetic Disorders

NCT00008307
View directory record Official record
Conditions
Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes
Interventions
anti-thymocyte globulin, cyclosporine, fludarabine phosphate, melphalan, methylprednisolone, mycophenolate mofetil, allogeneic bone marrow transplantation, peripheral blood stem cell transplantation, syngeneic bone marrow transplantation
Biological · Drug · Procedure
Lead sponsor
Herbert Irving Comprehensive Cancer Center
Other
Eligibility
1 Year to 80 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1998
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2014 · Synced Oct 21, 2026, 5:04 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Evaluation of Visual Outcomes of Monovision Patients Bilaterally Implanted With Nanoflex Intraocular Lenses

NCT01279122
View directory record Official record
Conditions
Patients Who Have Bilateral NanoFlex Implantation at Least 3 Months Previously
Interventions
Nanoflex IOL
Device
Lead sponsor
Innovative Medical
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 17, 2011 · Synced Oct 21, 2026, 5:04 PM EDT
Completed Not applicable Interventional Results available

EYEFILL® C. -US Viscoelastic Clinical Investigation

NCT02024711
View directory record Official record
Conditions
Cataract
Interventions
EYEFILL® C.-US Viscoelastic, Healon® Viscoelastic (CONTROL)
Device
Lead sponsor
Bausch Health Americas, Inc.
Industry
Eligibility
22 Years and older
Enrollment
262 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
8
States / cities
Phoenix, Arizona • Redding, California • Cape Coral, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 4, 2020 · Synced Oct 21, 2026, 5:04 PM EDT
Active, not recruiting Not applicable Interventional

A Prospective Study Comparing Visual Outcomes and Patient Satisfaction Following Implantation of the Clareon PanOptix Versus Tecnis Odyssey IOL in Patients Undergoing Cataract Surgery.

NCT07768475
View directory record Official record
Conditions
Cataracts
Interventions
Intraocular Lens Implant
Device
Lead sponsor
Nvision Laser Eye Centers
Industry
Eligibility
Not listed
Enrollment
266 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
4
States / cities
Rowland Heights, California • Poughkeepsie, New York • Hurst, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 21, 2026, 5:04 PM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

ACRYSOF® Restor Apodized Diffractive IOL Postmarket Evaluation of Clinical Outcomes and Life-Style Visual Performance RESTOR IOL SN60WF IOL (Control Group)

NCT00345111
View directory record Official record
Conditions
Refractive Assessment
Interventions
Clinical visual outcomes of bilateral implantation of Restore Intra Ocular Lens.
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 16, 2018 · Synced Oct 21, 2026, 5:04 PM EDT
Completed Phase 1 Interventional

Combination Chemotherapy With or Without Biological Therapy in Treating Patients With Refractory Solid Tumor or Lymphoma

NCT00005021
View directory record Official record
Conditions
Lymphoma, Small Intestine Cancer, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
filgrastim, carboplatin, paclitaxel, topotecan hydrochloride
Biological · Drug
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2003
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 11, 2013 · Synced Oct 21, 2026, 5:04 PM EDT
Completed Not applicable Interventional Results available

Symfony Toric Intraocular Lens Visual Outcomes

NCT03082599
View directory record Official record
Conditions
Cataract Bilateral, Astigmatism Bilateral
Interventions
Presbyopia and astigmatism correcting intraocular lens
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
40 Years to 99 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
4
States / cities
Stillwater, Minnesota • Garden City, New York • Mt. Pleasant, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 27, 2020 · Synced Oct 21, 2026, 5:04 PM EDT
Completed Phase 3 Interventional Results available

One-Piece Hydrophobic Acrylic Intraocular Lens in Subjects Undergoing Cataract Extraction

NCT01230060
View directory record Official record
Conditions
Aphakia, Cataract
Interventions
enVista
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Aliso Viejo, California
Source: ClinicalTrials.gov public record
Updated Aug 22, 2013 · Synced Oct 21, 2026, 5:04 PM EDT
Recruiting No phase listed Observational

Visual and Patient Reported Outcomes With Clareon TruPlus

NCT07648355
View directory record Official record
Conditions
Cataract
Interventions
Clareon TruPlus
Device
Lead sponsor
OVO LASIK + Lens
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Saint Louis Park, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 21, 2026, 5:04 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Depth of Focus Comparison Between Acrysof IQ and Acrysof Natural IOLs

NCT00886249
View directory record Official record
Conditions
Cataract, Vision
Interventions
Acrysof IQ, Acrysof Natural IOL
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
40 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 7, 2018 · Synced Oct 21, 2026, 5:04 PM EDT
Completed Not applicable Interventional Results available

Post-Market Evaluation of the EVO ICL

NCT05538754
View directory record Official record
Conditions
Myopia, Myopic Astigmatism
Interventions
EVO ICL
Device
Lead sponsor
Staar Surgical Company
Industry
Eligibility
21 Years to 45 Years
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
8
States / cities
Honolulu, Hawaii • Overland Park, Kansas • Omaha, Nebraska + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 21, 2026, 5:04 PM EDT
Not yet recruiting Not applicable Interventional

Is Nipple Stimulation Effective for Inducing Labor and Acceptable to Patients, Nurses, and Providers?

NCT07588529
View directory record Official record
Conditions
Pregnancy, Induction of Labor
Interventions
Electric breast pump for nipple stimulation, induction of labor
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 21, 2026, 5:04 PM EDT
Completed Phase 4 Interventional Results available

Contralateral ReSTOR / Monofocal or Phakic Eye

NCT00731640
View directory record Official record
Conditions
Cataracts
Interventions
ReSTOR
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Mar 23, 2010 · Synced Oct 21, 2026, 5:04 PM EDT
Completed No phase listed Observational

Evaluation of Visual Acuity of the Envista One-piece Acrylic Toric IOL MX60ET

NCT05739656
View directory record Official record
Conditions
Astigmatism
Interventions
CATARACT SURGERY
Procedure
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 22, 2023 · Synced Oct 21, 2026, 5:04 PM EDT
Not listed Not applicable Interventional

Visual Acuity Outcome Differences Between the Alcon Vivity Toric IOL and RxSight LAL+

NCT06574646
View directory record Official record
Conditions
Cataract
Interventions
LAL+, Clareon Vivity Toric IOL
Device
Lead sponsor
The Eye Associates
Other
Eligibility
45 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Aug 28, 2024 · Synced Oct 21, 2026, 5:04 PM EDT
Completed Phase 1Phase 2 Interventional

Doxorubicin Hydrochloride Liposome and Bortezomib in Treating Patients With Refractory Hematologic Cancer or Malignant Solid Tumor or Metastatic Breast Cancer

NCT00237627
View directory record Official record
Conditions
Breast Cancer, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Ovarian Cancer, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
PS-341, Doxil, Velcade
Drug
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2010
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 18, 2012 · Synced Oct 21, 2026, 5:04 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Visual Outcomes After Vivity Toric IOL Implantation

NCT04675489
View directory record Official record
Conditions
Refractive Assessment
Interventions
Procedure: Vivity Toric IOL
Other
Lead sponsor
EVP Eye Care
Other
Eligibility
45 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Grand Junction, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Oct 21, 2026, 5:04 PM EDT
Completed Not applicable Interventional Results available

Visual Performance With Clareon® Vivity® Intraocular Lenses (IOLs)

NCT06784063
View directory record Official record
Conditions
Astigmatism
Interventions
Clareon Vivity Extended Vision IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
3
States / cities
Bloomfield Hills, Michigan • Dallas, Texas • Sugar Land, Texas
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 21, 2026, 5:04 PM EDT
Completed Phase 1 Interventional

Bryostatin 1 and Interleukin-2 in Treating Patients With Refractory Solid Tumors or Lymphoma

NCT00003993
View directory record Official record
Conditions
Lymphoma, Small Intestine Cancer, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
aldesleukin, bryostatin 1
Biological · Drug
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1999
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 29, 2015 · Synced Oct 21, 2026, 5:04 PM EDT
Completed Phase 3 Interventional

Ondansetron in Treating Patients With Advanced Cancer and Chronic Nausea and Vomiting Not Caused by Cancer Treatment

NCT00006348
View directory record Official record
Conditions
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Nausea and Vomiting, Precancerous Condition, Small Intestine Cancer, Unspecified Adult Solid Tumor, Protocol Specific, Unspecified Childhood Solid Tumor, Protocol Specific
Interventions
ondansetron, placebo
Drug · Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2001
U.S. locations
12
States / cities
Scottsdale, Arizona • Urbana, Illinois • Des Moines, Iowa + 9 more
Source: ClinicalTrials.gov public record
Updated Jul 6, 2016 · Synced Oct 21, 2026, 5:04 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Spectacle Independence and Overall Satisfaction With AcrySof® Panoptix® Toric Intraocular Lens

NCT04128514
View directory record Official record
Conditions
Cataract
Interventions
Panoptix Toric
Device
Lead sponsor
Eye Center of North Florida
Other
Eligibility
40 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Panama City, Florida
Source: ClinicalTrials.gov public record
Updated Apr 1, 2022 · Synced Oct 21, 2026, 5:04 PM EDT
Completed Not applicable Interventional

AT ELANA 841P Posterior Chamber Intraocular Lens for Correction of Aphakia Following Cataract Removal

NCT06264232
View directory record Official record
Conditions
Cataract Senile
Interventions
Cataract Surgery
Device
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
22 Years to 100 Years
Enrollment
284 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
14
States / cities
Beverly Hills, California • Northridge, California • Orange, California + 11 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 21, 2026, 5:04 PM EDT
Completed Phase 4 Interventional

Comparison of Visual Outcomes and Patient Satisfaction After Cataract Surgery and Implantation of ReSTOR and ReZoom IOLs

NCT00366587
View directory record Official record
Conditions
Cataract Extraction
Interventions
Cataract surgery and IOL implantation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 14, 2018 · Synced Oct 21, 2026, 5:04 PM EDT