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ClinicalTrials.gov public records Last synced Oct 30, 2026, 3:07 PM EDT

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Showing 865–888 of 1,193 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: IT System Clear all
Completed Phase 1 Interventional Results available

Three Way Crossover Closed Loop Study With Xeris Glucagon

NCT03424044
View directory record Official record
Conditions
Type1diabetes
Interventions
Artificial Pancreas Controller in Dual Hormone Mode, Artificial Pancreas Controller in Single Hormone Mode, Artificial Pancreas Controller in Predictive Low Glucose Suspend Mode, XeriSol glucagon
Device · Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
21 Years to 50 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 27, 2020 · Synced Oct 30, 2026, 3:07 PM EDT
Recruiting Not applicable Interventional

Gait After THA: Direct Anterior vs Manual Posterior vs Robotic Posterior

NCT07226973
View directory record Official record
Conditions
Osteoarthritis (OA) of the Hip
Interventions
Total hip arthroplasty via direct anterior approach (manual, non-robotic), Total hip arthroplasty via posterior approach (manual, non-robotic), Robotic-assisted total hip arthroplasty via posterior approach
Procedure
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Metairie, Louisiana • New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 30, 2026, 3:07 PM EDT
Completed Not applicable Interventional Results available

AION BIOSYSTEMS, INC. Tempshield for Continuous Tempreature Monitoring

NCT07145541
View directory record Official record
Conditions
Fever, Sepsis
Interventions
Aion Tempshield Device
Device
Lead sponsor
AION Biosystems
Industry
Eligibility
1 Year to 4 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Oct 30, 2026, 3:07 PM EDT
Not listed No phase listed Observational

Treatment of Perianal Disease Using Adipose-derived Stem Cells

NCT03913572
View directory record Official record
Conditions
Perianal Fistula, Crohn Disease
Interventions
Injection of adipose-derived stem cells into perianal fistula
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Oct 30, 2026, 3:07 PM EDT
Active, not recruiting Not applicable Interventional

Comparing Suicide Prevention Interventions to Guide Follow-up Care: The SPRING Trial

NCT06128239
View directory record Official record
Conditions
Suicide, Suicide Prevention, Suicide and Self-harm
Interventions
Caring Contacts
Behavioral
Lead sponsor
St. Luke's Health System, Boise, Idaho
Other
Eligibility
12 Years and older
Enrollment
854 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Jul 9, 2025 · Synced Oct 30, 2026, 3:07 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neurobehavioral Changes Following Spaceflight Stressors

NCT07293494
View directory record Official record
Conditions
Stressor, Individual, Alcohol Impairment, Sleep Deprivation, Impairment, Cognitive
Interventions
Alcohol Administration, Sleep Deprivation, Control
Other · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 60 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 30, 2026, 3:07 PM EDT
Recruiting Phase 1Phase 2 Interventional

CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)

NCT03328078
View directory record Official record
Conditions
Relapsed Hematologic Malignancy, Refractory Hematologic Malignancy, Relapsed Primary Central Nervous System Lymphoma, Refractory Primary Central Nervous System Lymphoma
Interventions
Emavusertib, Ibrutinib
Drug
Lead sponsor
Curis, Inc.
Industry
Eligibility
18 Years and older
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
27
States / cities
Phoenix, Arizona • Duarte, California • Santa Monica, California + 19 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 30, 2026, 3:07 PM EDT
Enrolling by invitation No phase listed Observational

A Review of Precice Intramedullary Limb Lengthening (IMLL) System for Limb Lengthening Procedures in Children.

NCT06714110
View directory record Official record
Conditions
Limb Length Discrepancy
Interventions
Intramedullary Limb Lengthening Device, External Fixator Limb Lengthening Device
Device
Lead sponsor
NuVasive
Industry
Eligibility
0 Months to 12 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
West Palm Beach, Florida
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 30, 2026, 3:07 PM EDT
Recruiting Not applicable Interventional

Patient-reported Outcomes of Donor Site Healing Using Different Palatal Protection Techniques

NCT06892496
View directory record Official record
Conditions
Mucosal Erosion, Gingival Recession
Interventions
Visual Analog scale (VAS) questionnaire, Vacuum-formed retainer (VFR) technique, 3-D printed acrylic resin stent (3DS) technique, Flowable resin composite stent (FRC) technique, Photographs of the patient's palate, Measuring graft dimensions, Chairside Polymer Stent
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 30, 2026, 3:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Multicenter, Open-Label, Non-Comparative Study of the Safety and Contraceptive Efficacy of the Woman's Condom

NCT01223313
View directory record Official record
Conditions
Contraception
Interventions
Woman's Condom
Device
Lead sponsor
Premier Research
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
511 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
10
States / cities
Los Angeles, California • Baltimore, Maryland • New York, New York + 6 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 30, 2026, 3:07 PM EDT
Completed Phase 1 Interventional

Selinexor With Fludarabine and Cytarabine for Treatment of Refractory or Relapsed Leukemia or Myelodysplastic Syndrome

NCT02212561
View directory record Official record
Conditions
Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), Myelodysplastic Syndrome (MDS), Mixed Phenotype Acute Leukemia (MPAL)
Interventions
Selinexor, Fludarabine, Cytarabine, methotrexate/hydrocortisone/cytarabine
Drug
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
Up to 24 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
6
States / cities
Phoenix, Arizona • Palo Alto, California • Chicago, Illinois + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2020 · Synced Oct 30, 2026, 3:07 PM EDT
Terminated Not applicable Interventional Results available

Combined Renin Inhibition/Beta-blockade

NCT00627861
View directory record Official record
Conditions
Hypertension
Interventions
Aliskiren, Extended-release metoprolol
Drug
Lead sponsor
The Rogosin Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 24, 2015 · Synced Oct 30, 2026, 3:07 PM EDT
Completed Not applicable Interventional

Wheelchair Maintenance Training Program

NCT03909061
View directory record Official record
Conditions
Remote Maintenance Training Program
Interventions
Wheelchair Maintenance Training
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
Not listed
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 12, 2024 · Synced Oct 30, 2026, 3:07 PM EDT
Terminated Early Phase 1 Interventional

Blood Pressure Lowering Effects of Angiotensin-(1-7) in Primary Autonomic Failure

NCT02591173
View directory record Official record
Conditions
Autonomic Nervous System Disorders, Pure Autonomic Failure, Shy-Drager Syndrome, Orthostatic Hypotension, Dysautonomic
Interventions
Angiotensin-(1-7), Saline
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced Oct 30, 2026, 3:07 PM EDT
Not yet recruiting Phase 4 Interventional Accepts healthy volunteers

Study of Remimazolam for Cataract Surgery

NCT07325227
View directory record Official record
Conditions
Cataract Surgery Anesthesia
Interventions
Arm 1 Cataract Surgery performed with remimazolam as sedative, Arm 2 Cataract Surgery performed with standard of care sedative
Drug
Lead sponsor
Fred E, Shapiro
Other
Eligibility
55 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 30, 2026, 3:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Explorations of the Benefits of the ZeroG TRiP System to Improve Balance in Patients Following Stroke

NCT04919161
View directory record Official record
Conditions
Stroke, Balance; Distorted
Interventions
Body weight support system control group, Body weight support system with balance perturbations
Device
Lead sponsor
Gaylord Hospital, Inc
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Wallingford, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 17, 2021 · Synced Oct 30, 2026, 3:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Leveraging Implementation Science to Increase Access to Trauma Treatment for Incarcerated Drug Users

NCT04007666
View directory record Official record
Conditions
Substance Use Disorders, Drug Abuse, Alcohol Abuse, Posttraumatic Stress Disorder, PTSD, Recidivism, Depression
Interventions
Cognitive Processing Therapy, Control Group
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
2
States / cities
Osceola, Arkansas • West Memphis, Arkansas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Oct 30, 2026, 3:07 PM EDT
Completed Phase 1Phase 2 Interventional Results available

An Extension Study of HGT-HIT-045 Evaluating Long-Term Safety and Clinical Outcomes of Idursulfase-IT in Conjunction With Elaprase in Pediatric Participants With Hunter Syndrome and Cognitive Impairment

NCT01506141
View directory record Official record
Conditions
Hunter Syndrome
Interventions
Idursulfase-IT, Elaprase
Drug
Lead sponsor
Takeda
Industry
Eligibility
3 Years to 18 Years · Male only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2024
U.S. locations
7
States / cities
Chicago, Illinois • Chapel Hill, North Carolina • Portland, Oregon + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Oct 30, 2026, 3:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Guided Exercise on Functional Performance and Independence in Adults With Intellectual Disability

NCT04616638
View directory record Official record
Conditions
Intellectual Disability, Exercise, Obesity
Interventions
Resistance Training for Empowerment (RT-POWER), A traditional RT intervention
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 44 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Nov 5, 2020 · Synced Oct 30, 2026, 3:07 PM EDT
Completed Not applicable Interventional

Randomized, Prospective Comparison of Two Femoral Reaming Systems

NCT00594438
View directory record Official record
Conditions
Femur Fracture
Interventions
Synthes Reamer-Irrigator-Aspirator (RIA), Zimmer Sentinel Reamer
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 26, 2013 · Synced Oct 30, 2026, 3:07 PM EDT
Recruiting Not applicable Interventional

Evaluation of Scalp Cooling During Chemotherapy on Quality of Life and the Potential Role of Single Nucleotide Variations on Chemotherapy-Induced Alopecia and Hair Regrowth in the Appalachian Highlands Region

NCT07422376
View directory record Official record
Conditions
Alopecia
Interventions
Paxman Scalp Cooling System
Device
Lead sponsor
Charles Mays
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Kingsport, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 30, 2026, 3:07 PM EDT
Enrolling by invitation Not applicable Interventional

SHLH for Urban Adolescents (Efficacy Trial)

NCT07893015
View directory record Official record
Conditions
Poor Quality Sleep
Interventions
Sleeping Healthy, Living Healthy, Sleep for Teens
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
13 Years to 17 Years
Enrollment
294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Oct 30, 2026, 3:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Adolescents From Entering the Juvenile Justice System

NCT02147743
View directory record Official record
Conditions
Substance Use, Delinquency
Interventions
CCP+MDFT, CCP+SAU
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
12 Years to 17 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 28, 2014 · Synced Oct 30, 2026, 3:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Super Chef - an Online Program Promoting the Mediterranean Dietary Pattern to Lower Income Families

NCT05863559
View directory record Official record
Conditions
Feasibility, Diet, Healthy
Interventions
Super Chef: Family Fun in the Kitchen!
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
10 Years to 65 Years
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 30, 2026, 3:07 PM EDT