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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: IV ketorolac Clear all
Terminated Phase 4 Interventional Results available

Dosing of Ketorolac in the Emergency Department

NCT03464461
View directory record Official record
Conditions
Acute Pain
Interventions
Ketorolac
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
289 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 4, 2024 · Synced Sep 28, 2026, 5:18 AM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

A Comparative Efficacy Trial of IV Acetaminophen Versus IV Ketorolac for Emergency Department Treatment of Generalized Headache

NCT03472872
View directory record Official record
Conditions
Headache
Interventions
Ketorolac, Acetaminophen
Drug
Lead sponsor
Corewell Health South
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Saint Joseph, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 28, 2024 · Synced Sep 28, 2026, 5:18 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Ketorolac on Posterior Thoracolumbar Spinal Fusions

NCT03278691
View directory record Official record
Conditions
Thoracolumbar Spinal Fusions
Interventions
Saline, Ketorolac
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
1
States / cities
Southfield, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 19, 2023 · Synced Sep 28, 2026, 5:18 AM EDT
Completed Phase 2 Interventional Results available

Phase 2 Herniorrhaphy Study for Opioid Elimination

NCT03695367
View directory record Official record
Conditions
Postoperative Pain
Interventions
HTX-011, Luer lock applicator, Vial access device, Ibuprofen, Acetaminophen, Ketorolac
Drug · Device
Lead sponsor
Heron Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
5
States / cities
Anaheim, California • Pasadena, California • Draper, Utah + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Sep 28, 2026, 5:18 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Multimodal Pain Management After Robotic-Assisted Total Laparoscopic Hysterectomy

NCT04429022
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Gabapentin, Acetaminophen, Celecoxib, Ketorolac, Paracervical block with ropivacaine, Local anesthetic injection with ropivacaine at abdominal laparoscopic port sites, Hydromorphone, Oxycodone
Drug · Procedure
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
25 Years to 90 Years · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Williamsville, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced Sep 28, 2026, 5:18 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Intravenous Ketorolac Administration to Attenuate Post-procedural Pain Associated With Intrauterine Device Placement

NCT05875571
View directory record Official record
Conditions
IUD, Healthy Female, Contraception, IUD Insertion Complication
Interventions
Ketorolac, Placebo
Drug
Lead sponsor
Arkansas Children's Hospital Research Institute
Other
Eligibility
13 Years to 21 Years · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2024 · Synced Sep 28, 2026, 5:18 AM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of IV Diclofenac (DIV075V)for Pain After Elective Orthopedic Surgery

NCT00507026
View directory record Official record
Conditions
Postoperative Pain
Interventions
IV Diclofenac, IV ketorolac, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 85 Years
Enrollment
277 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
8
States / cities
Sheffield, Alabama • Phoenix, Arizona • San Clemente, California + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2021 · Synced Sep 28, 2026, 5:18 AM EDT
Recruiting Phase 4 Interventional

Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis Release

NCT07840183
View directory record Official record
Conditions
Ventral Hernia, Ventral Hernia Repair, Postoperative Pain
Interventions
Bupivicaine, Fentanyl, Thoracic epidural analgesia, Hydromorphone, Acetaminophen, Ketorolac, magnesium sulfate, Tramadol, Gabapentin, Cyclobenzaprine, transversus abdominis plane block
Drug · Device · Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Sep 28, 2026, 5:18 AM EDT
Terminated Phase 4 Interventional Results available

Steroids in Total Knee Arthroplasty

NCT02219581
View directory record Official record
Conditions
Postoperative Pain, Inflammation, Osteoarthritis
Interventions
Dexamethasone 10 mg, Dexamethasone 20 mg, Standard multimodal pain management regimen, Placebo
Drug
Lead sponsor
Thomas L Bradbury
Other
Eligibility
18 Years to 100 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Tucker, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 3, 2022 · Synced Sep 28, 2026, 5:18 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Autonomic Control of the Circulation and VDR

NCT03513770
View directory record Official record
Conditions
Venous Distension Reflex, Blood Pressure
Interventions
Wrist-to-elbow (W-E) occlusion, ketorolac tromethamine, saline control
Other · Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
21 Years to 35 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 28, 2026, 5:18 AM EDT
Recruiting Phase 4 Interventional

Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients

NCT06201676
View directory record Official record
Conditions
Orthopaedic Trauma, Chronic Opioid Use
Interventions
Ketorolac Injection, Standard of Care (SOC) Multimodal Analgesia
Drug · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
458 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 28, 2026, 5:18 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

TAP Block With Plain Bupivacaine Versus Wound Infiltration With Exparel for Postoperative Pain Management

NCT02074709
View directory record Official record
Conditions
Postoperative Pain
Interventions
Plain bupivacaine, Liposomal bupivacaine
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 3, 2018 · Synced Sep 28, 2026, 5:18 AM EDT
Terminated Phase 4 Interventional Results available

A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B301

NCT01507220
View directory record Official record
Conditions
Bowel Obstruction
Interventions
morphine sulfate, bupivacaine liposome extended-release injectable suspension
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 5, 2014 · Synced Sep 28, 2026, 5:18 AM EDT
Completed Phase 4 Interventional Results available

A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S23B504

NCT01509807
View directory record Official record
Conditions
Retraction of Colostomy
Interventions
IV morphine sulfate or Sponsor-approved equivalent, EXPAREL
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
3
States / cities
Tucson, Arizona • Orlando, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 6, 2014 · Synced Sep 28, 2026, 5:18 AM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Determining the Effect of an "Alternate Recovery Protocol" Versus Current Standard of Care After Cesarean Section

NCT03330119
View directory record Official record
Conditions
Pregnancy Related, Narcotic Use
Interventions
Alternate Management, Control
Drug
Lead sponsor
Brest, Norman A., M.D.
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
1,494 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Wynnewood, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 1, 2021 · Synced Sep 28, 2026, 5:18 AM EDT
Completed Phase 3 Interventional Results available

Ketamine Infusion for Comorbid PTSD and Chronic Pain

NCT04322968
View directory record Official record
Conditions
PTSD, Chronic Pain
Interventions
A single low dose ketamine infusion as compared to the IV infusion of active placebo - ketorolac on chronic pain and PTSD symptoms.
Drug
Lead sponsor
VA Ann Arbor Healthcare System
Federal
Eligibility
18 Years to 65 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 21, 2020 · Synced Sep 28, 2026, 5:18 AM EDT
Completed Phase 3 Interventional Results available

Evaluation of Anterior Quadratus Lumborum Block for Postoperative Analgesia in Hip Arthroscopy

NCT03432650
View directory record Official record
Conditions
Hip Disease
Interventions
Bupivacaine + dexamethasone, Ultrasound
Drug · Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 18, 2022 · Synced Sep 28, 2026, 5:18 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic Meniscus Surgery

NCT04246541
View directory record Official record
Conditions
Meniscus Tear, Tibial, Pain, Postoperative, Postoperative Complications, Ketorolac Adverse Reaction, Opioid Use
Interventions
Ketorolac, Oxycodone-Acetaminophen
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Sep 28, 2026, 5:18 AM EDT
Completed Phase 2 Interventional Results available

Toradol to Reduce Ureteroscopic Symptoms Trial

NCT03111381
View directory record Official record
Conditions
Urinary Lithiasis, Kidney Diseases, Kidney Stone, Pain, Postoperative
Interventions
Toradol
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 80 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 1, 2021 · Synced Sep 28, 2026, 5:18 AM EDT
Completed Phase 2 Interventional

Preeclampsia And Nonsteroidal Drugs for Analgesia: a Randomized Non Inferiority Trial

NCT03978767
View directory record Official record
Conditions
Preeclampsia Severe, Preeclampsia Postpartum
Interventions
Ibuprofen 600 mg, Ketorolac, Acetaminophen, Oxycodone
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Female only
Enrollment
287 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 28, 2026, 5:18 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Perioperative Ketamine for Pain With Gastric Bypass

NCT03448068
View directory record Official record
Conditions
Laparoscopic Gastric Bypass Surgery, Ketamine
Interventions
Ketamine, Standard therapy
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 69 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Sep 28, 2026, 5:18 AM EDT
Terminated Phase 2Phase 3 Interventional

Opioid-Free Pain Control Regimen Following Robotic Radical Prostatectomy

NCT05597878
View directory record Official record
Conditions
Pain Management, Opioid Use, Prostate Cancer
Interventions
Oxycodone, Acetaminophen, Ketamine, Ketorolac
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
40 Years to 75 Years · Male only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 28, 2026, 5:18 AM EDT
Recruiting Phase 4 Interventional

Safety of Short-course of NSAIDs in Pediatric Patients With CKD

NCT06860711
View directory record Official record
Conditions
Chronic Kidney Disease, Pediatric Urology
Interventions
NSAIDs, Placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Months to 25 Years
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 28, 2026, 5:18 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Addition of Muscle Relaxants in a Multimodal Analgesic Regimen for Analgesia After Primary Total Knee Arthroplasty

NCT04574791
View directory record Official record
Conditions
Pain, Postoperative
Interventions
TiZANidine 2 MG Oral Capsule
Drug
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years to 80 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 4, 2020 · Synced Sep 28, 2026, 5:18 AM EDT