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Showing 1–24 of 39 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Image-guided surgical system Clear all
Completed Early Phase 1 Interventional

MRI-Guided Stereotactic Body Radiation Therapy in Treating Patients With Liver Metastases or Liver Cancer

NCT02683200
View directory record Official record
Conditions
Adult Hepatocellular Carcinoma, Metastatic Malignant Neoplasm in the Liver
Interventions
Image-Guided Adaptive Radiation Therapy, Stereotactic Body Radiation Therapy
Radiation
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 20, 2023 · Synced Sep 2, 2026, 4:04 PM EDT
Completed Not applicable Interventional

Transoral Robotic Surgery (TORS) for Sleep Apnea

NCT01187160
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Transoral robotic surgery (TORS)
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 21, 2016 · Synced Sep 2, 2026, 4:04 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Breast Ultrasound Image Reviewed With Assistance of Deep Learning Algorithms

NCT03706534
View directory record Official record
Conditions
Breast Cancer, Breast Lesions, Breast Mass
Interventions
Ultrasound Image review with CADe, Ultrasound Image review with CADx, Ultrasound Image manual review, Biopsy
Device · Procedure
Lead sponsor
Samsung Medison
Industry
Eligibility
19 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 28, 2019 · Synced Sep 2, 2026, 4:04 PM EDT
Terminated Phase 2 Interventional

Image Guided System for Orthopaedic Surgery

NCT00022802
View directory record Official record
Conditions
Orthopaedic Trauma, Hip Fracture
Interventions
Image-guided surgical system
Device
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
1
States / cities
Park Ridge, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 8, 2009 · Synced Sep 2, 2026, 4:04 PM EDT
Recruiting Phase 2 Interventional

Preoperative Hypofractionated Radiotherapy With FOLFOX for Esophageal or Gastroesophageal Junction Adenocarcinoma

NCT06078709
View directory record Official record
Conditions
Clinical Stage I Esophageal Adenocarcinoma AJCC v8, Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8, Clinical Stage II Esophageal Adenocarcinoma AJCC v8, Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8, Clinical Stage III Esophageal Adenocarcinoma AJCC v8, Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
Interventions
Biospecimen Collection, Computed Tomography, Endoscopic Ultrasound, Esophagogastroduodenoscopy, Fluorouracil, Hypofractionated Radiation Therapy, Leucovorin Calcium, Oxaliplatin, Positron Emission Tomography, Survey Administration, Docetaxel, Durvalumab
Procedure · Drug · Radiation + 2 more
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 2, 2026, 4:04 PM EDT
Completed Not applicable Interventional Results available

Radiofrequency Identification Technology in Locating Non-palpable Breast Lesions in Patients Undergoing Surgery

NCT03202472
View directory record Official record
Conditions
Breast Neoplasm, Lesion
Interventions
Implanted Medical Device, Mammography, Questionnaire Administration, Radiofrequency (RFID) -Guided Localization, Ultrasonography
Device · Procedure · Other
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
19 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 23, 2020 · Synced Sep 2, 2026, 4:04 PM EDT
Completed Not applicable Interventional Results available

Radiofrequency Chip for Localization of Non-Palpable Breast Lesions

NCT03684408
View directory record Official record
Conditions
Breast Tumor
Interventions
RFID Localization, Wire Localization, RFID and Wire Localization
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older · Female only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 24, 2022 · Synced Sep 2, 2026, 4:04 PM EDT
Active, not recruiting Not applicable Interventional

Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)

NCT05051033
View directory record Official record
Conditions
Mitral Valve Regurgitation
Interventions
Mitral valve repair, Transcatheter edge-to-edge repair
Procedure · Device
Lead sponsor
Annetine Gelijns
Other
Eligibility
60 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
24
States / cities
Los Angeles, California • San Francisco, California • Stanford, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 2, 2026, 4:04 PM EDT
Completed No phase listed Observational

Evaluation of a Minimally Invasive Image-Guided Surgery System for Hepatic Ablation Procedures

NCT01238666
View directory record Official record
Conditions
Liver Cancer
Interventions
Not listed
Lead sponsor
Pathfinder Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 13, 2012 · Synced Sep 2, 2026, 4:04 PM EDT
Terminated No phase listed Observational

Feasibility of a Minimally Invasive Image-Guided Surgery System for Hepatic Procedures

NCT01238653
View directory record Official record
Conditions
Liver Cancer
Interventions
Not listed
Lead sponsor
Pathfinder Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 7, 2012 · Synced Sep 2, 2026, 4:04 PM EDT
Completed Not applicable Interventional

Evaluating the Safety and Effectiveness of the Flex Robotic System for the Surgical Removal of Colorectal Lesions

NCT05674123
View directory record Official record
Conditions
Colorectal Neoplasm
Interventions
Colonoscopy, Endoscopic Ultrasound, Medical Chart Review, Medical Device Usage and Evaluation, Resection
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
22 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 11, 2023 · Synced Sep 2, 2026, 4:04 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Indocyanine Green for Central Nervous System Tumors

NCT02710240
View directory record Official record
Conditions
Suspected Central Nervous System Tumors
Interventions
Indocyanine Green (ICG), Intraoperative near-infrared (NIR)
Drug · Radiation
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
336 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 26, 2021 · Synced Sep 2, 2026, 4:04 PM EDT
Completed Early Phase 1 Interventional

Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Glioma

NCT02278510
View directory record Official record
Conditions
Malignant Glioma, WHO Grade III or IV Recurrent Glioma
Interventions
Topotecan, Gadolinium DTPA, Cleveland Multiport Catheter
Drug · Device
Lead sponsor
Michael Vogelbaum, MD, PhD
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 30, 2017 · Synced Sep 2, 2026, 4:04 PM EDT
Completed Early Phase 1 Interventional

Contrast-Enhanced Ultrasound Identification of Sentinel Nodes in Esophageal Cancer

NCT03578224
View directory record Official record
Conditions
Esophagus
Interventions
Endoscopic Ultrasound-Guided Fine-Needle Aspiration (EUS-FNA), Contrast-Enhanced Ultrasound, Fine-Needle Aspiration, Sonazoid (Perflubutane)
Procedure · Drug
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Other
Eligibility
21 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 17, 2025 · Synced Sep 2, 2026, 4:04 PM EDT
Completed No phase listed Observational

Feasibility of a Minimally Invasive Image-Guided Surgery System for Hepatic Procedures

NCT01237990
View directory record Official record
Conditions
Liver Cancer
Interventions
Not listed
Lead sponsor
Pathfinder Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 19, 2012 · Synced Sep 2, 2026, 4:04 PM EDT
Completed Not applicable Interventional Results available

Navigation of the Pelvic Floor in Bladder Exstrophy Using Pre-operative MRI

NCT01878500
View directory record Official record
Conditions
Bladder Exstrophy
Interventions
Intraoperative stereotactic imaging with VectorVision
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
Up to 7 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 20, 2021 · Synced Sep 2, 2026, 4:04 PM EDT
Completed No phase listed Observational

Feasibility of a Minimally Invasive Image-Guided Surgery System for Hepatic Procedures

NCT01286428
View directory record Official record
Conditions
Liver Cancer
Interventions
Not listed
Lead sponsor
Pathfinder Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 13, 2012 · Synced Sep 2, 2026, 4:04 PM EDT
Active, not recruiting Phase 1 Interventional

TSR-042 in Addition to Standard of Care Definitive Radiation for Inoperable Endometrial Cancer

NCT03955978
View directory record Official record
Conditions
Endometrial Cancer, Cancer of the Endometrium
Interventions
TSR-042, Brachytherapy, Endometrial biopsy, Blood draw for immune response
Drug · Radiation · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Sep 2, 2026, 4:04 PM EDT
Completed Not applicable Interventional

Cryotherapy for Malignant Dysphagia in Patients With Advanced Esophageal Cancer

NCT02606396
View directory record Official record
Conditions
Esophageal Adenocarcinoma
Interventions
Cryotherapy, Esophagogastroduodenoscopy (EGD), Endoscopic ultrasound (EUS)
Procedure
Lead sponsor
Hunter Holmes Mcguire Veteran Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 2, 2026, 4:04 PM EDT
Completed Phase 1 Interventional

A Comparison of Methods for Assisting Needle Angle Selection During Image-guided Tissue Biopsy

NCT01218854
View directory record Official record
Conditions
Lung Neoplasms, Liver Neoplasms, Kidney Neoplasms, Cancer
Interventions
Needle angle measurement
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Sep 2, 2026, 4:04 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

A Feasibility Study of a Modular Video Augmentation System for Image-Guided Skull Base Surgery

NCT01591954
View directory record Official record
Conditions
Feasibility of Video Augmentation System, Value of Video Augmentation Navigation
Interventions
Video Augmentation
Device
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 30, 2016 · Synced Sep 2, 2026, 4:04 PM EDT
Completed Phase 2 Interventional

CYTALUX™for the Intraoperative Imaging of Prostate Cancer

NCT06434909
View directory record Official record
Conditions
Prostate Cancer
Interventions
Cytalux™ (pafolacianine) for fluorescent imaging, Image Guided Surgery
Drug · Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older · Male only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
3
States / cities
Carmel, Indiana • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 2, 2026, 4:04 PM EDT
Terminated Phase 2 Interventional Results available

Clinical Application of Image-Guided Liver Surgery

NCT00878215
View directory record Official record
Conditions
Hepatocellular Cancer
Interventions
Explorer Liver Image Guided System, Explorer Liver Passive Tracking, Liver surgery, Liver abalation
Device · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2011
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 12, 2018 · Synced Sep 2, 2026, 4:04 PM EDT
Recruiting Early Phase 1 Interventional

Feasibility Evaluation of the Muse Magnetic Resonance Guided Focused Ultrasound System

NCT05291507
View directory record Official record
Conditions
Breast Cancer
Interventions
Muse MRgFUS System
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older · Female only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Sep 2, 2026, 4:04 PM EDT