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Conditions: PTSD
Interventions: Exposure Therapy; Behavioral
Lead sponsor: University of Central Florida; Other
Eligibility: 18 Years to 64 Years
Enrollment: 134 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: Prolonged Exposure (PE); Behavioral
Lead sponsor: Research Foundation for Mental Hygiene, Inc.; Other
Eligibility: 18 Years to 60 Years
Enrollment: 95 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: PTSD, Post Traumatic Stress Disorder
Interventions: Traditional Exposure Therapy (ET) Treatment, Stepwise Augmented Reality (AR) Component with Traditional Exposure Treatment for Nonresponders; Behavioral
Lead sponsor: Wayne State University; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: PTSD
Interventions: written exposure therapy, CPT, cognitive only; Behavioral
Lead sponsor: Boston VA Research Institute, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 169 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2021
U.S. locations: 2
States / cities: Killeen, Texas • San Antonio, Texas

Conditions: Trauma, Psychological, Trauma and Stressor Related Disorders
Interventions: Trauma-Focused Cognitive Behavioral Therapy (TF-CBT), School-Adapted TF-CBT (S-TF); Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 7 Years and older
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Post Traumatic Stress Disorder, Opioid-use Disorder
Interventions: Prolonged Exposure Therapy, Attendance-based monetary incentives; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older
Enrollment: 82 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Chronic Posttraumatic Stress Disorder
Interventions: Revisiting the Trauma memories, Processing the trauma memories, Psychoeducation, Trauma Memory Retrieval Trial, Exposure to video clips related to the patient's trauma, Breathing retraining, Exposure Homework, Compound extinction; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years to 65 Years
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2020
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Depression, Anxiety
Interventions: Positive Affect Treatment, Negative Affect Treatment; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 65 Years
Enrollment: 85 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 2
States / cities: Los Angeles, California • Dallas, Texas

Conditions: Chronic Post-Traumatic Stress Disorder, Marijuana Abuse
Interventions: Brief Imaginal Exposure; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 65 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Traumatic Injury, PTSD, Posttraumatic Stress Disorder
Interventions: Treatment as Usual, Brief Prolonged Exposure Therapy; Behavioral
Lead sponsor: Baylor Research Institute; Other
Eligibility: 18 Years to 75 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 3
States / cities: Dallas, Texas • Temple, Texas • Milwaukee, Wisconsin

Conditions: PTSD
Interventions: Exposure Therapy, Interpersonal Psychotherapy; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 208 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: PTSD
Interventions: trauma-focused treatment; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 178 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 3
States / cities: Boston, Massachusetts • Charleston, South Carolina • Madison, Wisconsin

Conditions: Pain, Chronic, Pain, Musculoskeletal, Anxiety
Interventions: dCBT; Behavioral
Lead sponsor: Boston University Charles River Campus; Other
Eligibility: 18 Years and older
Enrollment: 86 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Combat Disorders, Stress Disorders, Post-Traumatic
Interventions: Exposure therapy, D-Cycloserine, Placebo pill; Behavioral · Drug · Other
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Posttraumatic Stress Disorder, PTSD
Interventions: Modular Cognitive Processing Therapy, Modular Prolonged Exposure Therapy, Step Down Treatment, Digital Interventions, Cognitive Processing Therapy (CPT), Prolonged Exposure (PE); Behavioral
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years and older
Enrollment: 302 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 4
States / cities: Augusta, Georgia • Ann Arbor, Michigan • Battle Creek, Michigan + 1 more

Conditions: Stress Disorders, Post Traumatic
Interventions: Prolonged Exposure Therapy (PE), Virtual Reality Exposure Therapy (VRET), Waitlist; Behavioral
Lead sponsor: National Center for Telehealth and Technology; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 162 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Tacoma, Washington

Conditions: Depressive Symptoms, Stress Disorder, Acute, Prolonged Grief Disorder, Alcohol Abuse, Stress Disorders, Post-Traumatic
Interventions: Accelerated Resolution Therapy; Behavioral
Lead sponsor: University of South Florida; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Trauma, Posttraumatic Stress Disorder
Interventions: Personalized Stepped Care Cognitive Behavioral Therapy for Children after Trauma (pSC-CBT-CT); Behavioral
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 7 Years to 14 Years
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Major Depressive Disorder, Posttraumatic Stress Disorder, Panic Disorder and Agoraphobia
Interventions: Transdiagnostic Behavior Therapy, Cognitive Processing Therapy for PTSD, Cognitive Behavioral Therapy for MDD, Cognitive Behavioral Therapy for Panic Disorder; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 80 Years
Enrollment: 304 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Osteo Arthritis Knee
Interventions: Cognitive-Behavioral Intervention, Pain Education; Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 45 Years to 85 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Anxiety
Interventions: Digital CBT; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older · Female only
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Social Anxiety Disorder (Social Phobia), Public Speaking Anxiety, Anhedonia, ANXIETY DISORDERS (or Anxiety and Phobic Neuroses), Phobic Disorders
Interventions: Positive Affect Treatment - Behavioral (PAT-B), Relaxation Treatment, Exposure Therapy; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 60 Years
Enrollment: 94 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Posttraumatic Stress Disorder
Interventions: DCS, Placebo; Drug · Other
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Stress Disorders, Post-Traumatic, Substance Use Disorders
Interventions: Prolonged Exposure Therapy, Cognitive Processing Therapy, Present Centered Therapy; Behavioral
Lead sponsor: Center for Veterans Research and Education; Other
Eligibility: 18 Years and older
Enrollment: 426 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 14
States / cities: San Diego, California • Tampa, Florida • Atlanta, Georgia + 11 more

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Effectiveness of Trauma Management Therapy and Prolonged Exposure Therapy

fMRI Predictors of Treatment Response in Posttraumatic Stress Disorder (PTSD)

Advanced Wireless Augmented Reality-Enhanced Exposure Therapy for Posttraumatic Stress Disorder

Brief Treatment for Posttraumatic Stress Disorder

Systematic Redesign of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT)

Prolonged Exposure Therapy for PTSD and Opioid Use Disorder

Enhancing Exposure Therapy for Post-traumatic Stress Disorder

Treatment for Affect Dimensions

Short-Term Exposure for PTSD

Trauma BPE Prolonged Exposure Therapy for Injured Individuals Admitted to a Level I Trauma Center

A Trial Comparing Interpersonal Therapy to Exposure Therapy for PTSD Due to Military Sexual Trauma (MST) in Male and Female Military Personnel

Written Exposure Therapy Versus Prolonged Exposure: a Non-inferiority Trial

Assessment of the Efficacy of Digital CBT for Anxiety in Adults With Chronic Musculoskeletal Pain

A Placebo-Controlled Trial of D-Cycloserine and Exposure Therapy for Combat-PTSD

Adaptive Decision-making And Personalized Treatment for PTSD (ADAPT-PTSD)

Exposure Therapy for Active Duty Soldiers With Post Traumatic Stress Disorder

Neurophysiological Mechanisms of Accelerated Resolution Therapy (ART)

Increasing Treatment Access in Trauma Exposed Children: Developing an Adapted Step One Intervention (Pilot)

Comparing Individual Therapies for Veterans With Depression, PTSD, and Panic Disorder

Study of Pain Catastrophizing

Transforming Health and Reducing Perinatal Anxiety Through Virtual Engagement

Reward Processing and Exposure Therapy for Social Anxiety Disorder

Imaginal Exposure & D-Cycloserine (DCS) for Posttraumatic Stress Disorder (PTSD)

Psychotherapy for PTSD Among Veterans Also Receiving Drug or Alcohol Treatment