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ClinicalTrials.gov public records Last synced Sep 27, 2026, 5:28 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Immediate Antibiotics Clear all
Completed Not applicable Interventional

Impact of a Prehospital Sepsis Protocol on Timely Antibiotic Administration and Subsequent Adverse Events

NCT05502107
View directory record Official record
Conditions
Sepsis
Interventions
PRESS Intervention
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
984 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
3
States / cities
Atlanta, Georgia • Iowa City, Iowa • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 10, 2025 · Synced Sep 27, 2026, 5:28 AM EDT
Not yet recruiting Phase 3 Interventional

Precision Management of Urinary Tract Symptoms in Older Women

NCT07686055
View directory record Official record
Conditions
Urinary Tract Infection (Diagnosis)
Interventions
Antibiotics
Drug
Lead sponsor
Megan Bradley
Other
Eligibility
65 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 27, 2026, 5:28 AM EDT
Withdrawn Phase 1 Interventional

Topical Antibiotic Prophylaxis for Nasal Packing Post-ESBS

NCT04946435
View directory record Official record
Conditions
Intracranial Pathology
Interventions
Antibiotic Irrigation
Combination Product
Lead sponsor
Carl Snyderman
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 8, 2023 · Synced Sep 27, 2026, 5:28 AM EDT
Recruiting Not applicable Interventional

Diagnostic Stewardship Intervention to Reduce Inappropriate Antibiotic Use for Urinary Tract Infections in Primary Care

NCT07246837
View directory record Official record
Conditions
Urinary Tract Infection(UTI), Antimicrobial Stewardship, Primary Care
Interventions
MSCC Educational Tool
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 27, 2026, 5:28 AM EDT
Not yet recruiting No phase listed Observational

SnapChole: An International, Time-Bound Prospective Platform Study of Management Strategies and Outcomes in Acute Calculous Cholecystitis

NCT07568080
View directory record Official record
Conditions
Cholecystitis, Acute
Interventions
Not listed
Lead sponsor
European Society for Trauma and Emergency Surgery
Other
Eligibility
18 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 27, 2026, 5:28 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Outpatient Antibiotics Following Previable Rupture of Membranes (pPPROM) Between 18 0/7 and 22 6/7 Weeks Gestational Age

NCT05345457
View directory record Official record
Conditions
Pregnancy Preterm, Pregnancy Prom, PROM, Preterm (Pregnancy), PROM (Pregnancy), Premat Rupture Membranes Preterm Unspec to Length of Time Between Rupture/Labor, Premature Birth
Interventions
Azithromycin Pill, Amoxicillin Pill
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
3
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 27, 2026, 5:28 AM EDT
Withdrawn Not applicable Interventional

Prospective Study of Clostridium Difficile in Children Undergoing Colonoscopy

NCT01472978
View directory record Official record
Conditions
C. Difficile Infection
Interventions
metronidazole
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
7 Years to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Sep 27, 2026, 5:28 AM EDT
Completed Not applicable Interventional

Shared Decision Making in Parents of Children With Acute Otitis Media

NCT02872558
View directory record Official record
Conditions
Acute Otitis Media
Interventions
Acute Otitis Media Choice Decision Aid, Usual Care
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
6 Months to 18 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 3, 2022 · Synced Sep 27, 2026, 5:28 AM EDT
Recruiting Not applicable Interventional

Comparing Antibiotic Treatment Strategies for Children With Pneumonia in Outpatient Settings: (STAMPP)

NCT06986148
View directory record Official record
Conditions
Community Acquired Pneumonia (CAP), Community Acquired Pneumonia
Interventions
Immediate Antibiotic Prescribing Group Instructions, Safety Net Antibiotic Prescribing (SNAP) Group Instructions
Other
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
12 Months to 71 Months
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
4
States / cities
Atlanta, Georgia • Chicago, Illinois • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Sep 27, 2026, 5:28 AM EDT
Recruiting Not applicable Interventional

Interventions to De-implement Unnecessary Antibiotic Prescribing for Children With Ear Infections

NCT06034080
View directory record Official record
Conditions
Acute Otitis Media, Ear Infection, Pediatric Infectious Disease
Interventions
Changes to the electronic health record (EHR), Individualized audit and feedback reporting for clinicians, Clinician education sessions, Use of a shared decision-making (SDM) aide, Shared decision-making (SDM) education
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
6 Months to 17 Years
Enrollment
1,566 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
3
States / cities
Denver, Colorado • Chicago, Illinois • Murray, Utah
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced Sep 27, 2026, 5:28 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Postoperative Antibiotic Requirements Following Immediate Breast Reconstruction

NCT01244698
View directory record Official record
Conditions
Bacterial Infection, Anti-infective Agents, Breast Implantation
Interventions
Cefadroxil discontinued early, Cefadroxil until drain removal
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older · Female only
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated May 12, 2014 · Synced Sep 27, 2026, 5:28 AM EDT
Completed No phase listed Observational

Blood Culture Improvement Guidelines and Diagnostic Stewardship for Antibiotic Reduction in Critically Ill Children

NCT03441126
View directory record Official record
Conditions
Sepsis, Bacteremia
Interventions
Multicenter Quality Improvement program
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
Not listed
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
5
States / cities
St Louis, Missouri • Cleveland, Ohio • Portland, Oregon + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Sep 27, 2026, 5:28 AM EDT
Not listed Not applicable Interventional

Effectiveness for Interventions to Minimize Surgical Site Infections

NCT01153191
View directory record Official record
Conditions
Infections
Interventions
Normal saline pressurized irrigation, sub-q gentamicin
Procedure · Drug
Lead sponsor
Dallas VA Medical Center
Federal
Eligibility
18 Years to 95 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 3, 2011 · Synced Sep 27, 2026, 5:28 AM EDT
Terminated Phase 3 Interventional Results available

A Safety and Tolerability Study of Doripenem Compared With Cefepime in Children Hospitalized With Complicated Urinary Tract Infections

NCT01110408
View directory record Official record
Conditions
Complicated Urinary Tract Infections or Pyelonephritis
Interventions
Doripenem, Doripenem placebo, Cefepime, Cefepime placebo, Amoxicillin/clavulanate potassium
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
3 Months to 18 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
11
States / cities
Little Rock, Arkansas • Oakland, California • Orange, California + 8 more
Source: ClinicalTrials.gov public record
Updated Jul 14, 2014 · Synced Sep 27, 2026, 5:28 AM EDT
Completed Phase 2 Interventional Results available

A Dose-Ranging Study Evaluating the Efficacy, Safety, and Tolerability of GSK2140944 in the Treatment of Uncomplicated Urogenital Gonorrhea Caused by Neisseria Gonorrhoeae

NCT02294682
View directory record Official record
Conditions
Gonorrhea
Interventions
GSK2140944
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
12
States / cities
Fountain Valley, California • Los Angeles, California • Palm Springs, California + 8 more
Source: ClinicalTrials.gov public record
Updated May 22, 2017 · Synced Sep 27, 2026, 5:28 AM EDT
Not yet recruiting Not applicable Interventional

Proximal Splenic Artery Embolization (PSAE) for the Treatment of Refractory Ascites in Decompensated Cirrhosis

NCT07755059
View directory record Official record
Conditions
Ascites, Liver Cirrhosis, Hypertension, Portal
Interventions
Proximal Splenic Artery Embolization
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 27, 2026, 5:28 AM EDT
Recruiting Phase 4 Interventional

Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction

NCT06511232
View directory record Official record
Conditions
Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Interventions
Intraosseous Morphine
Drug
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 40 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 27, 2026, 5:28 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Regional Prophylactic Vancomycin With Restricted Tourniquet Time in Primary Total Knee Replacement

NCT03506347
View directory record Official record
Conditions
Arthropathy of Knee Joint
Interventions
Vancomycin
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 26, 2020 · Synced Sep 27, 2026, 5:28 AM EDT
Completed Not applicable Interventional

Trial of Antimicrobial Restraint in Presumed Pneumonia

NCT04438187
View directory record Official record
Conditions
Healthcare-Associated Pneumonia, Sepsis
Interventions
antimicrobial initiation
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 18, 2024 · Synced Sep 27, 2026, 5:28 AM EDT
Withdrawn No phase listed Observational

Bronchiectasis: Evaluation of an Educational Intervention

NCT01315626
View directory record Official record
Conditions
Bronchiectasis
Interventions
Primary Care Educational event
Other
Lead sponsor
Hill-Rom
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Shelbyville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 17, 2015 · Synced Sep 27, 2026, 5:28 AM EDT
Withdrawn Not applicable Interventional

The Mount Sinai Diabetic Foot Ulcer Prospective Trial

NCT03404895
View directory record Official record
Conditions
Diabetes, Diabetic Foot Ulcer, Edema
Interventions
Conventional Therapy, Venous Stent(s)
Device
Lead sponsor
Windsor Ting
Other
Eligibility
30 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Sep 27, 2026, 5:28 AM EDT
Completed Phase 2 Interventional Results available

Gentamicin Bladder Instillation in Individuals With Spinal Cord Injury Having Chronic Urinary Tract Infections

NCT03931408
View directory record Official record
Conditions
Neurogenic Bladder, Spinal Cord Injuries
Interventions
Gentamicin Sulfate, Placebo instillation (saline alone), No instillation
Drug · Other
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Sep 27, 2026, 5:28 AM EDT
Completed Not applicable Interventional Results available

Efficacy of Post-operative Antibiotic Prophylaxis for Thoracic Surgery Requiring Tube Thoracostomy

NCT00818766
View directory record Official record
Conditions
Antibiotic Prophylaxis
Interventions
cefazolin or vancomycin, Placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
251 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 25, 2017 · Synced Sep 27, 2026, 5:28 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Feasibility and Acceptability of Point of Care Rapid Syphilis Testing Among Patients Seeking Family Planning Services in Hawai'i

NCT07358949
View directory record Official record
Conditions
Syphilis Infection
Interventions
Rapid Syphilis Test
Diagnostic Test
Lead sponsor
Queen's Medical Center
Other
Eligibility
14 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Sep 27, 2026, 5:28 AM EDT