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ClinicalTrials.gov public records Last synced Oct 17, 2026, 4:10 PM EDT

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Showing 1–24 of 49 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Immediate Breast Reconstruction Clear all
Completed No phase listed Observational Results available

Immediate Postmastectomy Breast Reconstruction (Strattice Breast)

NCT00619762
View directory record Official record
Conditions
Breast Cancer
Interventions
LTM - a porcine-based surgical mesh
Device
Lead sponsor
LifeCell
Industry
Eligibility
18 Years and older · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Chicago, Illinois • Great Neck, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 8, 2016 · Synced Oct 17, 2026, 4:10 PM EDT
Terminated Phase 3 Interventional Results available

Pre-op Paravertebral Blocks to Decrease Post-op Pain Following Mastectomy With Immediate Tissue Expander (TE) Reconstruction

NCT02161705
View directory record Official record
Conditions
Postoperative Pain, Postoperative Nausea and Vomiting, Quality of Life
Interventions
Ropivacaine, Saline
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Oct 17, 2026, 4:10 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Earlier Breast Cancer Detection Using Automated Whole Breast Ultrasound With Mammography, Including Cost Comparisons

NCT00649337
View directory record Official record
Conditions
Breast Neoplasms, Ultrasonography
Interventions
Comparison of Automated Whole Breast Ultrasound Screening with Blinded Screening Mammography
Procedure
Lead sponsor
SonoCine, Inc.
Industry
Eligibility
35 Years to 90 Years · Female only
Enrollment
4,650 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2010
U.S. locations
1
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Apr 1, 2008 · Synced Oct 17, 2026, 4:10 PM EDT
Completed Not applicable Interventional

Post-Operative Outcomes of Low Thermal Dissection vs. Traditional Electrosurgery

NCT03711916
View directory record Official record
Conditions
Breast Cancer, Mastectomy, Perfusion; Complications, Hemostasis
Interventions
PlasmaBlade 3.0S
Device
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 18, 2019 · Synced Oct 17, 2026, 4:10 PM EDT
Withdrawn Not applicable Interventional

Prepectoral vs Partial Subpectoral Two-Stage Implant-Based Breast Reconstruction

NCT04874402
View directory record Official record
Conditions
Breast Reconstruction Following Mastectomy
Interventions
Prepectoral approach, Partial Subpectoral approach
Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
19 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Jun 18, 2023 · Synced Oct 17, 2026, 4:10 PM EDT
Recruiting Not applicable Interventional

ILR to Prevent BRCL_MCC 23608

NCT07127003
View directory record Official record
Conditions
Breast Cancer Lymphedema
Interventions
Immediate Lymphatic Reconstruction
Procedure
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 17, 2026, 4:10 PM EDT
Completed Phase 1 Interventional Results available

Optimizing Decision Making About Breast Reconstruction After Mastectomy: A Patient-Centered Approach

NCT03346161
View directory record Official record
Conditions
Breast Cancer
Interventions
Usual care American Society of Plastic Surgeons booklet "Breast Reconstruction", Decision tool, Usual Care Group - Outcome Measures, Decision Group - Outcome Measures, Demographic and Background Questions
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 6, 2019 · Synced Oct 17, 2026, 4:10 PM EDT
Completed Phase 3 Interventional

Tissue Expander/Implant Reconstruction: A Single-Blinded, Randomized, Controlled Trial

NCT00639106
View directory record Official record
Conditions
Breast Cancer
Interventions
Alloderm, Questionnaires, Without ALLODERM, Questionnaires
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
21 Years to 75 Years · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2018
U.S. locations
3
States / cities
Ann Arbor, Michigan • New York, New York • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 3, 2018 · Synced Oct 17, 2026, 4:10 PM EDT
Completed Not applicable Interventional Results available

Tissue Expander Breast Reconstruction Study on Breast Volume and Shape Change

NCT01222390
View directory record Official record
Conditions
Contour Irregularity of Reconstructed Breast
Interventions
Contour Profile Tissue Expander
Device
Lead sponsor
Northwestern University
Other
Eligibility
25 Years to 85 Years · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Oct 17, 2026, 4:10 PM EDT
Completed Phase 1Phase 2 Interventional

Percutaneous Removal and Margin Ablation for Breast Cancer

NCT00574301
View directory record Official record
Conditions
Breast Cancer
Interventions
Percutaneous Removal and Margin Ablation
Procedure
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2011
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jul 25, 2013 · Synced Oct 17, 2026, 4:10 PM EDT
Completed Not applicable Interventional Results available

Surgical Site Infection With 0.05% Chlorhexidine (CHG) Compared to Triple Antibiotic Irrigation

NCT02395614
View directory record Official record
Conditions
Breast Cancer
Interventions
Chlorhexidine irrigation, triple antibiotic irrigation
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 81 Years · Female only
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 26, 2022 · Synced Oct 17, 2026, 4:10 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluating AlloMax in Immediate Expander-Based Breast Reconstruction Study

NCT01372917
View directory record Official record
Conditions
Malignant Neoplasm of the Breast, Acquired Absence of the Breast
Interventions
Not listed
Lead sponsor
National Center for Plastic Surgery, Virginia
Other
Eligibility
25 Years to 65 Years · Female only
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
McLean, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 13, 2012 · Synced Oct 17, 2026, 4:10 PM EDT
Completed Phase 3 Interventional

Immunonutrition and Carbohydrate Loading Strategies in Breast Reconstruction

NCT03764943
View directory record Official record
Conditions
Wound Complication, Wound Heal, Complications Wound, Surgical Wound Infection, Surgical Site Infection, Breast Cancer, Mastectomy; Lymphedema
Interventions
Impact Advanced Recovery
Dietary Supplement
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 29, 2022 · Synced Oct 17, 2026, 4:10 PM EDT
Not listed Phase 4 Interventional

Role of TXA in Patients Undergoing Breast Free Flap Reconstruction

NCT06428682
View directory record Official record
Conditions
Breast Cancer, Blood Loss, Surgical
Interventions
Tranexamic acid, Placebo
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Oct 17, 2026, 4:10 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Postoperative Antibiotic Requirements Following Immediate Breast Reconstruction

NCT01244698
View directory record Official record
Conditions
Bacterial Infection, Anti-infective Agents, Breast Implantation
Interventions
Cefadroxil discontinued early, Cefadroxil until drain removal
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older · Female only
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated May 13, 2014 · Synced Oct 17, 2026, 4:10 PM EDT
Not yet recruiting Not applicable Interventional

Thermal Preconditioning in Mastectomy Patients With Immediate Breast Reduction

NCT07516483
View directory record Official record
Conditions
Breast Reconstruction After Mastectomy
Interventions
1 Cycle Thermal Preconditioning, 3 Cycles Thermal Preconditioning, No Intervention
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 17, 2026, 4:10 PM EDT
Recruiting Phase 3 Interventional

A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People With Breast Cancer

NCT06144164
View directory record Official record
Conditions
Lymphedema, Lymphedema Arm, Lymphedema of Upper Arm, Breast Cancer, Breast Carcinoma, Female Breast Cancer
Interventions
Immediate Lymphatic Reconstruction, Volumetric arm measurements, Lymphatic massage, Range of motion exercises, Compression garment use
Procedure · Diagnostic Test · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
285 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 17, 2026, 4:10 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Pectoralis (II) Block With Liposomal Bupivacaine vs Bupivacaine for Breast Surgery

NCT03383198
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Liposomal bupivacaine right injection, Liposomal bupivacaine left injection
Drug
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Oct 17, 2026, 4:10 PM EDT
Completed Phase 2 Interventional

Compare Outcomes Between Two Acellular Dermal Matrices

NCT02891759
View directory record Official record
Conditions
Breast Cancer
Interventions
Alloderm RTU, Cortiva 1mm Allograft Dermis, Skin or nipple-sparing mastectomy, Breast Q, Surgery
Other · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
22 Years to 70 Years · Female only
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 6, 2023 · Synced Oct 17, 2026, 4:10 PM EDT
Completed No phase listed Observational

SPY Intra-Operative Angiography & Skin Perfusion in Immediate Breast Reconstruction w/ Implants

NCT01315119
View directory record Official record
Conditions
Breast Cancer
Interventions
SPY Intra-Operative Angiography
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2021 · Synced Oct 17, 2026, 4:10 PM EDT
Completed No phase listed Observational

Evaluation of SOMAVAC 100 Sustained Vacuum System

NCT04845256
View directory record Official record
Conditions
Breast Cancer
Interventions
SOMAVAC 100 Sustained Vacuum System
Device
Lead sponsor
University of Tennessee
Other
Eligibility
21 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Oct 17, 2026, 4:10 PM EDT
Completed No phase listed Observational

A Pilot Study to Evaluate Nipple-Areolar Complex (NAC) Sparing Mastectomy

NCT00539227
View directory record Official record
Conditions
Breast Cancer
Interventions
NAC Sparing Mastectomy, Questionnaire
Procedure · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Female only
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 26, 2013 · Synced Oct 17, 2026, 4:10 PM EDT
Completed Phase 2 Interventional

Delayed-Immediate Breast Reconstruction

NCT00473122
View directory record Official record
Conditions
Breast Cancer
Interventions
Delayed-Immediate Breast Reconstruction
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 15, 2016 · Synced Oct 17, 2026, 4:10 PM EDT
Active, not recruiting Not applicable Interventional

Pre- Versus Sub-pectoral Implant-based Breast Reconstruction After Skin-sparing Mastectomy or Nipple-sparing Mastectomy OPBC-02PREPEC

NCT04293146
View directory record Official record
Conditions
Breast Reconstruction, Implant-Based Breast Reconstruction (IBBR)
Interventions
pre-pectoral IBBR, sub-pectoral IBBR
Procedure
Lead sponsor
University Hospital, Basel, Switzerland
Other
Eligibility
18 Years and older · Female only
Enrollment
382 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2033
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 13, 2024 · Synced Oct 17, 2026, 4:10 PM EDT