Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:51 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1273–1296 of 1,807 matching trials from the live ClinicalTrials.gov search.
Conditions
Emphysema, COPD
Interventions
IBV® Valve System
Device
Lead sponsor
Olympus Corporation of the Americas
Industry
Eligibility
40 Years to 74 Years
Enrollment
277 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2017
U.S. locations
34
States / cities
Birmingham, Alabama • Los Angeles, California • Mission Viejo, California + 29 more
Conditions
Obesity, Morbid
Interventions
vBloc Maestro Rechargeable System, vBloc Achieve Weight Management Program, Control Weight Management (CWM) program
Device · Other
Lead sponsor
ReShape Lifesciences
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
2
States / cities
Scottsdale, Arizona • Mineola, New York
Completed No phase listed Observational

iBeat Wristwatch Validation Study

NCT03711695
Conditions
Arrythmia, Cardiac
Interventions
iBeat wristwatch device
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 85 Years
Enrollment
55 participants
Timeline
2018
U.S. locations
1
States / cities
San Francisco, California
Conditions
Osteo Arthritis Knee, Osteoarthritis
Interventions
Total Knee Replacement
Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
22 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
5
States / cities
Baltimore, Maryland • Crosby, Minnesota • Charlotte, North Carolina + 2 more
Conditions
Brain Tumor, Malignant Neoplasm of Fourth Ventricle of Brain
Interventions
Ommaya Reservoir, Methotrexate, Leucovorin
Procedure · Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Up to 22 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
Houston, Texas
Active, not recruiting Phase 3 Interventional Results available

Vagus Nerve Stimulation for Moderate to Severe Rheumatoid Arthritis

NCT04539964
Conditions
Rheumatoid Arthritis
Interventions
Implant Procedure, Conventional Synthetic DMARD, Active stimulation, Non-active stimulation
Procedure · Drug · Device
Lead sponsor
SetPoint Medical Corporation
Industry
Eligibility
22 Years to 75 Years
Enrollment
243 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
42
States / cities
Mesa, Arizona • Phoenix, Arizona • Tucson, Arizona + 37 more
Not listed No phase listed Observational

Impella RP Flex with Smart Assist

NCT06637644
Conditions
Right Ventricular (RV) Dysfunction
Interventions
Right-sided ventricular assist device
Device
Lead sponsor
Abiomed Inc.
Industry
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
31
States / cities
Birmingham, Alabama • Tucson, Arizona • Little Rock, Arkansas + 23 more
Completed Not applicable Interventional Results available

Remote Device Interrogation In The Emergency Department

NCT01871090
Conditions
Heart Disease, Cardiovascular Disease, Heart Failure, Arrhythmias, Cardiac
Interventions
Unpaired remote monitoring transmitter
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Zanesville, Ohio
Conditions
Myocardial Ischemia
Interventions
Heart failure or coronary disease, Heart transplant patients, Orthotopic Heart Transplant Patients, Heart Surgery Patients, Blood Draw
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Veteran Ear Acupuncture Pilot Project

NCT04208659
Conditions
Chronic Pain Syndrome, Pain, Fibromyalgia, Low Back Pain, Neuropathic Pain, Neuropathy, Painful, Musculoskeletal Pain, Chronic Pain
Interventions
Self-administration of auricular acupuncture without prosthesis, Self-administration of auricular acupuncture with prosthesis
Procedure
Lead sponsor
Chillicothe VA Medical Center
Federal
Eligibility
18 Years to 120 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chillicothe, Ohio
Conditions
Spinal Tumor
Interventions
Spinal SBRT (Standard Dose), Spinal SBRT (Higher Dose), Gold Seed Implantation, Questionnaires
Radiation · Procedure · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2023
U.S. locations
1
States / cities
Houston, Texas
Conditions
Implantable Defibrillator User
Interventions
Ellipse VR ICD and Durata/Optisure lead
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
227 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
26
States / cities
Phoenix, Arizona • Bakersfield, California • La Jolla, California + 22 more
Conditions
Transfemoral Amputees
Interventions
Vanderbilt Powered Knee-Ankle Prosthesis, Microprocessor (MP) Knee Prosthesis
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Neoplasms, Benign, Neoplasms, Malignant
Interventions
OxyChip
Device
Lead sponsor
Periannan Kuppusamy
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Lebanon, New Hampshire
Active, not recruiting Not applicable Interventional

Responsive Deep Brain Stimulator for Essential Tremor

NCT02649166
Conditions
Essential Tremor
Interventions
Deep brain stimulation, Closed-loop deep brain stimulation
Device
Lead sponsor
University of Florida
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Atrial Fibrillation
Interventions
Internal Cardioversion, External Cardioversion
Procedure
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years to 99 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Lexington, Kentucky
Completed Not applicable Interventional Results available

The PQ Bypass Pivotal IDE Intra-arterial Stent Graft Study

NCT04130737
Conditions
Peripheral Arterial Disease
Interventions
TORUS Stent Graft System
Device
Lead sponsor
Endologix
Industry
Eligibility
18 Years to 90 Years
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
32
States / cities
Mesa, Arizona • Phoenix, Arizona • Yuma, Arizona + 28 more
Conditions
Periprosthetic Joint Infections
Interventions
EP Granules with Tobramycin, empty voids
Device
Lead sponsor
Elute, Inc.
Industry
Eligibility
22 Years and older
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
16
States / cities
Los Angeles, California • Washington D.C., District of Columbia • Skokie, Illinois + 12 more
Completed Not applicable Interventional Results available

Cycling Versus Continuous Mode in Neuromodulator Programming

NCT02551822
Conditions
Urinary Incontinence, Urge
Interventions
sacral neuromodulator
Device
Lead sponsor
University of New Mexico
Other
Eligibility
21 Years and older · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Albuquerque, New Mexico
Conditions
Tetraplegia/Tetraparesis, Quadriplegia, Cervical Spinal Cord Injury, Amyotrophic Lateral Sclerosis, Quadriplegia/Tetraplegia, Tetraplegic; Paralysis, Stroke
Interventions
N1 Implant, R1 Robot
Device
Lead sponsor
Neuralink Corp
Industry
Eligibility
22 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
1
States / cities
Dallas, Texas
Completed Phase 4 Interventional Results available

RNS® System LTT Study

NCT00572195
Conditions
Epilepsy
Interventions
RNS® System
Device
Lead sponsor
NeuroPace
Industry
Eligibility
18 Years and older
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2018
U.S. locations
33
States / cities
Phoenix, Arizona • Los Angeles, California • San Francisco, California + 29 more
Terminated Not applicable Interventional Results available

Spinal Stimulation During Exercise in Heart Failure

NCT02659202
Conditions
Heart Failure
Interventions
Precision Spinal Cord Stimulator System
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Completed No phase listed Observational Accepts healthy volunteers

HydroMARK Post-market Clinical Follow-up Study

NCT04622696
Conditions
Breast Cancer
Interventions
Ultrasound imaging
Diagnostic Test
Lead sponsor
Devicor Medical Products, Inc.
Industry
Eligibility
18 Years and older
Enrollment
730 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
3
States / cities
Columbus, Ohio • Toledo, Ohio • Morgantown, West Virginia
Conditions
Emphysema
Interventions
RePneu Lung Volume Reduction Coil System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
35 Years and older
Enrollment
315 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
23
States / cities
Birmingham, Alabama • Los Angeles, California • Mountain View, California + 19 more