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ClinicalTrials.gov public records Last synced Oct 5, 2026, 6:57 AM EDT

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Showing 73–96 of 109 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: In vivo exposure therapy Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

D-Cycloserine-Enhancer of One-Session Treatment for Phobia of Heights

NCT01037101
View directory record Official record
Conditions
Height Phobia
Interventions
In Vivo Exposure Therapy, Virtual Reality Exposure Therapy, D-Cycloserine, Placebo
Behavioral · Drug
Lead sponsor
CAMC Health System
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Oct 14, 2013 · Synced Oct 5, 2026, 6:57 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Increasing Treatment Access in Trauma Exposed Children: Developing an Adapted Step One Intervention (Pilot)

NCT07396935
View directory record Official record
Conditions
Trauma, Posttraumatic Stress Disorder
Interventions
Personalized Stepped Care Cognitive Behavioral Therapy for Children after Trauma (pSC-CBT-CT)
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
7 Years to 14 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 5, 2026, 6:57 AM EDT
Completed Not applicable Interventional Results available

Integrating Animal-Assisted Therapy Into Trauma-Focused Cognitive-Behavioral Therapy for Maltreated Youth

NCT03135119
View directory record Official record
Conditions
Child Abuse, Posttraumatic Stress
Interventions
TF-CBT, TF-CBT+AAT
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
6 Years to 17 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Harrisburg, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 18, 2022 · Synced Oct 5, 2026, 6:57 AM EDT
Not yet recruiting Not applicable Interventional

A Randomized Clinical Trial of Ex Vivo Corneal Cross-Linking of Donor Keratoplasty Tissue for Keratoconus Used for Keratoplasty in Keratoconus Patients

NCT04584125
View directory record Official record
Conditions
Keratoconus
Interventions
Riboflavin 5'-phosphate in 20% dextran ophthalmic solution) 0.146% with UV light, Riboflavin 5'-phosphate in 20% dextran ophthalmic solution) 0.146% without UV light
Drug
Lead sponsor
Joseph B. Ciolino, MD
Other
Eligibility
18 Years to 50 Years
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 5, 2026, 6:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness of Trauma Management Therapy and Prolonged Exposure Therapy

NCT04549493
View directory record Official record
Conditions
PTSD
Interventions
Exposure Therapy
Behavioral
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 64 Years
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated May 10, 2024 · Synced Oct 5, 2026, 6:57 AM EDT
Completed Not applicable Interventional Results available

Group Treatment for PTSD: A Randomized Clinical Trial With Veterans

NCT01544088
View directory record Official record
Conditions
PTSD
Interventions
Group Cognitive Behavioral Treatment (GCBT), Present Centered Group Treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older · Male only
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 23, 2020 · Synced Oct 5, 2026, 6:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Management of Chronic Pain and PTSD in Gulf War Veterans With tDCS+Prolonged Exposure

NCT04236284
View directory record Official record
Conditions
Chronic Pain, PTSD
Interventions
Home-based tDCS, Prolonged Exposure Therapy
Device · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 3, 2023 · Synced Oct 5, 2026, 6:57 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

GETSmart: Guided Education and Training Via Smart Phones to Promote Resilience

NCT02170194
View directory record Official record
Conditions
Subthreshold PTSD
Interventions
Resilience Enhancement Training via Smart Phone, Daily Text Messages
Behavioral
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 1, 2016 · Synced Oct 5, 2026, 6:57 AM EDT
Completed Not applicable Interventional

Brain Imaging of Psychotherapy for Posttraumatic Stress Disorder (PTSD)

NCT01507948
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Prolonged exposure
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 60 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
Palo Alto, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 23, 2017 · Synced Oct 5, 2026, 6:57 AM EDT
Completed Not applicable Interventional Results available

Exposure, D-cycloserine Enhancement, and Functional Magnetic Resonance Imaging (fMRI) in Snake Phobics

NCT01450306
View directory record Official record
Conditions
Specific Phobia
Interventions
D-cycloserine, Exposure therapy, Placebo
Drug · Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 15, 2024 · Synced Oct 5, 2026, 6:57 AM EDT
Recruiting Not applicable Interventional

Adaptive Decision-making And Personalized Treatment for PTSD (ADAPT-PTSD)

NCT07176273
View directory record Official record
Conditions
Posttraumatic Stress Disorder, PTSD
Interventions
Modular Cognitive Processing Therapy, Modular Prolonged Exposure Therapy, Step Down Treatment, Digital Interventions, Cognitive Processing Therapy (CPT), Prolonged Exposure (PE)
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
4
States / cities
Augusta, Georgia • Ann Arbor, Michigan • Battle Creek, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 5, 2026, 6:57 AM EDT
Completed Not applicable Interventional

Effectiveness of Intensive Cognitive Behavioral Therapy in Treating Adolescent Panic Disorder and Agoraphobia

NCT00576719
View directory record Official record
Conditions
Panic Disorder, Agoraphobia
Interventions
Intensive panic control treatment without parent involvement, Intensive panic control treatment with parent involvement, Waitlist control
Behavioral · Other
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
12 Years to 17 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 5, 2026, 6:57 AM EDT
Recruiting Not applicable Interventional

Mechanisms Underlying Efficacy of Prolonged Exposure

NCT05788302
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Prolonged Exposure
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Oct 5, 2026, 6:57 AM EDT
Completed Phase 2 Interventional Results available

A Trial of Extracorporeal Photopheresis, Pentostatin, and Total Body Irradiation in Patients Undergoing Reduced Intensity Allogeneic Stem Cell Transplantation for the Treatment of Malignancies

NCT00402714
View directory record Official record
Conditions
Hematologic Malignancies
Interventions
extracorporeal photopheresis, Pentostatin, Total Body Irradiation
Procedure · Drug · Radiation
Lead sponsor
Yale University
Other
Eligibility
18 Years to 75 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
3
States / cities
New Haven, Connecticut • Boston, Massachusetts • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 18, 2017 · Synced Oct 5, 2026, 6:57 AM EDT
Completed Not applicable Interventional Results available

Mechanisms of Change, Motivation, and Treatment Outcome in Alcohol Dependence - Posttraumatic Stress Disorder

NCT01409707
View directory record Official record
Conditions
Alcohol Dependence, Posttraumatic Stress Disorder
Interventions
Trauma-focused exposure therapy, Motivational enhancement + trauma-focused exposure therapy, Healthy lifestyles sessions
Behavioral
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Mar 10, 2014 · Synced Oct 5, 2026, 6:57 AM EDT
Recruiting Not applicable Interventional

A Trial Comparing Interpersonal Therapy to Exposure Therapy for PTSD Due to Military Sexual Trauma (MST) in Male and Female Military Personnel

NCT03803332
View directory record Official record
Conditions
PTSD
Interventions
Exposure Therapy, Interpersonal Psychotherapy
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 85 Years
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 5, 2026, 6:57 AM EDT
Completed Not applicable Interventional

Efficacy of Targeted Memory Reactivation for Enhancing Exposure Therapy

NCT04663672
View directory record Official record
Conditions
Claustrophobia, Obsessive-Compulsive Disorder, Arachnophobia
Interventions
Experimental Scent, Control Scent, No-Scent Control, In-Vivo Exposure
Other · Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 11, 2020 · Synced Oct 5, 2026, 6:57 AM EDT
Completed Not applicable Interventional

Enhanced Smoking Cessation Intervention for Smokers Exposed to the World Trade Center (WTC) Disaster

NCT02538601
View directory record Official record
Conditions
Cigarette Smoking, Post Traumatic Stress Disorder, Signs and Symptoms, Respiratory
Interventions
CBT-A, CBT-S
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Sep 2, 2015 · Synced Oct 5, 2026, 6:57 AM EDT
Recruiting Not applicable Interventional

Mechanisms Underlying the Efficacy of Prolonged Exposure

NCT05663151
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Prolonged Exposure Therapy for Posttraumatic Stress Disorder
Behavioral
Lead sponsor
VA Boston Healthcare System
Federal
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Oct 5, 2026, 6:57 AM EDT
Recruiting Not applicable Interventional

Self-Adhering Magnetic Device to Treat Corneal Exposure

NCT06291818
View directory record Official record
Conditions
Paralytic Lagophthalmos, Corneal Exposure
Interventions
temporary magnetic system for tarsorrhaphy (MST)
Device
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 5, 2026, 6:57 AM EDT
Completed Not applicable Interventional

Exposure Therapy for Active Duty Soldiers With Post Traumatic Stress Disorder

NCT01193725
View directory record Official record
Conditions
Stress Disorders, Post Traumatic
Interventions
Prolonged Exposure Therapy (PE), Virtual Reality Exposure Therapy (VRET), Waitlist
Behavioral
Lead sponsor
National Center for Telehealth and Technology
Federal
Eligibility
18 Years to 65 Years
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Apr 14, 2015 · Synced Oct 5, 2026, 6:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transdiagnostic Behavioral Activation Therapy for Youth Anxiety and Depression

NCT01829100
View directory record Official record
Conditions
Depressive Disorder, Anxiety Disorders
Interventions
Group Behavioral Activation Therapy (GBAT)
Behavioral
Lead sponsor
Rutgers University
Other
Eligibility
11 Years to 15 Years
Enrollment
895 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 5, 2026, 6:57 AM EDT
Completed Not applicable Interventional Results available

GET Living: Graded Exposure Treatment for Children and Adolescents With Chronic Pain

NCT03699007
View directory record Official record
Conditions
Pediatric Pain, Chronic Pain, Widespread, Musculoskeletal Pain
Interventions
Graded Exposure Therapy (GET Living), Multidisciplinary Pain Management (MPM)
Behavioral
Lead sponsor
Laura E Simons
Other
Eligibility
8 Years to 18 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Menlo Park, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 5, 2026, 6:57 AM EDT
Recruiting Not applicable Interventional

Project COMET: Massed Prolonged Exposure for PTSD and SUD

NCT06968832
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Substance Use Disorders (SUD), Comorbidity, Trauma and Stressor Related Disorders
Interventions
Massed Prolonged Exposure Therapy (M-PE), Standard outpatient SUD care
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 5, 2026, 6:57 AM EDT