Independent directory Public ClinicalTrials.gov records United States
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Showing 289–312 of 547 matching trials from the live ClinicalTrials.gov search.
Conditions
Leukemia
Interventions
c-myb antisense oligonucleotide G4460, filgrastim, busulfan, cyclophosphamide, autologous bone marrow transplantation, in vitro-treated bone marrow transplantation
Biological · Drug · Procedure
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1993 – 2002
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Renal Cell Carcinoma
Interventions
Lenvatinib, Everolimus, Partial or Radical Cytoreductive Nephrectomy
Drug · Procedure
Lead sponsor
Yousef Zakharia
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Precancerous/Nonmalignant Condition, Small Intestine Cancer
Interventions
anti-thymocyte globulin, filgrastim, cladribine, cyclophosphamide, etoposide, methylprednisolone, tacrolimus, allogeneic bone marrow transplantation, in vitro-treated peripheral blood stem cell transplantation
Biological · Drug · Procedure
Lead sponsor
Northwestern University
Other
Eligibility
Up to 45 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2000
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Ovarian Neoplasms, BRCA 1 Gene Mutation, BRCA 2 Gene Mutation, Serous Tubal Intraepithelial Carcinoma, Early Detection of Ovarian Cancer
Interventions
Galleri Multi-Cancer Early Detection (MCED) Blood Test
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
35 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2039
U.S. locations
2
States / cities
New York, New York • Houston, Texas
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Lipidomics Screening of Anti-inflammatory Drugs and Drug Candidates in Vitro - Part A

NCT02095288
Conditions
Healthy
Interventions
Blood draw
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Fetal Aortic Valvuloplasty for Evolving Hypoplastic Left Heart Syndrome

NCT06342999
Conditions
Hypoplastic Left Heart Syndrome
Interventions
Fetal Aortic Valvuloplasty Procedure, Emerge Monorail and Over-The-Wire PTCA Dilatation Catheter, Trek RX and Mini Trek RX Coronary Dilatation Catheter
Procedure · Device
Lead sponsor
Mauro H. Schenone
Other
Eligibility
Up to 45 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2036
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Resistance Bacterial
Interventions
T2Resistance Panel
Diagnostic Test
Lead sponsor
T2 Biosystems
Industry
Eligibility
18 Years and older
Enrollment
1,566 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
10
States / cities
Birmingham, Alabama • San Francisco, California • Tampa, Florida + 7 more
Conditions
Hematological Disorders
Interventions
Not listed
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
12 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2030
U.S. locations
1
States / cities
The Bronx, New York
Not listed Phase 1 Interventional Accepts healthy volunteers

Cold Apheresis Platelets in PAS

NCT02754414
Conditions
Platelet Transfusion
Interventions
Apheresis platelet collection, Refrigerated storage of apheresis platelets in PAS/plasma, Infusion of aliquot of autologous radiolabeled platelets, In vitro tests
Procedure · Other · Radiation
Lead sponsor
Bloodworks
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Conditions
T-Cell Lymphoproliferative Disorder
Interventions
IdentiClone Dx TRG Assay
Diagnostic Test
Lead sponsor
Invivoscribe, Inc.
Industry
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
San Diego, California
Conditions
Female Infertility Due to Diminished Ovarian Reserve
Interventions
Human Growth Hormone, Follicle Stimulating Hormone
Drug
Lead sponsor
Center for Human Reproduction
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sperm Selection by Microfluidic Separation Improves Embryo Quality

NCT03085433
Conditions
Sperm DNA Fragmentation, Embryo Quality, Fertility Disorders, Infertility, Infertility, Male, Infertility Unexplained
Interventions
Microfluidic Sperm Sorting, in vitro fertilization
Device · Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
393 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
San Francisco, California
Conditions
Acute Coronary Syndrome, Myocardial Infarction
Interventions
Elecsys® Troponin T hs Gen 6, Blood sample collection
Diagnostic Test · Procedure
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
20 Years and older
Enrollment
5,429 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
26
States / cities
El Centro, California • La Jolla, California • Gainesville, Florida + 21 more
Conditions
Infertility
Interventions
Morphology, GemART assay
Other
Lead sponsor
Gema Diagnostics
Industry
Eligibility
21 Years to 39 Years · Female only
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
4
States / cities
Oak Brook, Illinois • Indianapolis, Indiana • Iowa City, Iowa + 1 more
Conditions
Short Bowel Syndrome (SBS), SBS Associated With Intestinal Failure (SBS-IF)
Interventions
Apraglutide, Placebo
Drug
Lead sponsor
VectivBio AG
Industry
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
17
States / cities
Los Angeles, California • Denver, Colorado • Washington D.C., District of Columbia + 14 more
Conditions
Peripheral Artery Disease
Interventions
Ivus (Intravascular Ultrasound) of Amputation Specimens, IVUS (Intravascular Ultrasound)
Other · Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
DS Stage I Plasma Cell Myeloma, DS Stage II Plasma Cell Myeloma, DS Stage III Plasma Cell Myeloma, Refractory Plasma Cell Myeloma
Interventions
Autologous Hematopoietic Stem Cell Transplantation, Gamma-Secretase Inhibitor RO4929097, Hematopoietic Stem Cell Mobilization, In Vitro-Treated Peripheral Blood Stem Cell Transplantation, Laboratory Biomarker Analysis, Melphalan
Procedure · Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Tampa, Florida
Completed No phase listed Observational

KIDScore D3 Clinical Study

NCT03740828
Conditions
Infertility
Interventions
KIDScore D3
Device
Lead sponsor
Vitrolife
Industry
Eligibility
Female only
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
6
States / cities
San Diego, California • San Francisco, California • Miami, Florida + 2 more
Not yet recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Synaptic Mechanisms of Intermittent Theta Burst Stimulation for Major Depressive Disorder

NCT07593222
Conditions
Major Depression, Healthy Participants
Interventions
Sham iTBS, TMS, D-cycloserine, Dextromethophan, Placebo
Device · Drug
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Belmont, Massachusetts
Conditions
Single Gene Disorders
Interventions
Preimplantation Genetic Diagnosis
Other
Lead sponsor
Natera, Inc.
Industry
Eligibility
Not listed
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Redwood City, California
Conditions
Hematopoietic/Lymphoid Cancer
Interventions
Allogenic T cell-depleted hematopoietic stem cell transplantation
Biological
Lead sponsor
Leland Metheny
Other
Eligibility
Up to 80 Years
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Celiac Disease
Interventions
Not listed
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Infertility, Recurrent Pregnancy Loss
Interventions
Microfluidics chamber, Density Gradient Centrifugation
Device · Other
Lead sponsor
Lawrence Engmann
Other
Eligibility
18 Years to 42 Years · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Farmington, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers

Single Embryo Transfer of a Euploid Embryo Versus Double Embryo Transfer

NCT01408433
Conditions
Infertility
Interventions
Single Embryo Transfer, Double embryo transfer
Other
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
18 Years to 43 Years
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
2
States / cities
Morristown, New Jersey • Allentown, Pennsylvania