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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:32 AM EST

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Showing 145–168 of 274 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Increase sleep Clear all

Conditions: Loneliness
Interventions: Interpretation Bias Modification for Loneliness, Healthy Habits Psychoeducation and Relaxation; Behavioral
Lead sponsor: Florida State University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Sleep Disorders
Interventions: Zolpidem, Escitalopram, Placebo; Drug
Lead sponsor: University of Pittsburgh; Other
Eligibility: 20 Years to 50 Years
Enrollment: 69 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2008
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Depression, Depressive Disorder, Major, Depressive Disorder, Unipolar Depression, Major Depressive Disorder
Interventions: Venlafaxine XR, Aerobic Exercise, Lorazepam; Drug · Other
Lead sponsor: Kirk Erickson, PhD; Other
Eligibility: 60 Years to 79 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Depression, Anxiety, Fatigue, Sleepiness, Sleep Disruption
Interventions: Simulated Dawn Light Box, Sleep Hygiene instructions; Device · Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 46 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: High Blood Pressure
Interventions: Thiazide Treatment Group, Intensified Thiazide Treatment Group, Combination Medication Treatment Group; Drug
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 35 Years to 59 Years · Male only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Obstructive Sleep Apnea, PTSD, Posttraumatic Stress Disorder
Interventions: CBT-OSA, Sleep Education; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 99 Years
Enrollment: 76 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Obesity
Interventions: Behavioral Child Tx Contacts, Behavioral Parent-Tx Contacts, Dietary and Physical Activity Information; Behavioral · Other
Lead sponsor: University of Florida; Other
Eligibility: 8 Years to 12 Years
Enrollment: 314 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Sleep Apnea, Sleep Disturbance
Interventions: Couples-based treatment- Patient, Couples-based treatment- Partner, Information control- Patient, Information control- Partner; Behavioral · Other
Lead sponsor: University of Utah; Other
Eligibility: 35 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Tuscon, Arizona • Salt Lake City, Utah

Conditions: Insomnia, Insomnia Chronic
Interventions: SleepSpaceRx CBT-I-IoT-AI, SleepEZ CBTi, Sleep Hygiene IoT; Behavioral
Lead sponsor: Proactive Life Inc; Industry
Eligibility: 55 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Depression - Major Depressive Disorder, Mood, Sleep, Physical Activity
Interventions: Intern Health Study behavioral change mobile notification; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Pain, Opioid Use
Interventions: PainTracker, Current Opioid Misuse Measure; Behavioral
Lead sponsor: University of Southern California; Other
Eligibility: 65 Years and older
Enrollment: 286 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Physical Conditioning
Interventions: Health Fair, Pedometer, Text Messaging, Social Network Support; Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 21 Years and older · Male only
Enrollment: 290 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Fibromyalgia
Interventions: TNX-102 SL Tablet, 5.6 mg, Placebo SL Tablet; Drug
Lead sponsor: Tonix Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 457 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 33
States / cities: Phoenix, Arizona • Oceanside, California • Santa Ana, California + 30 more

Conditions: Post Surgical Pain, Surgery
Interventions: Self-directed mindfulness utilizing a multi-sensor EEG-supported device with neurofeedback-assisted and technology-supported meditation, Provider-directed mindfulness, Conventional Care; Other
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 10 Years to 18 Years
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Diabetic Retinopathy
Interventions: Amplify-RHYTHM; Behavioral
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 40 Years to 65 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Asthma, Sleep Apnea
Interventions: Bilevel PAP (4 weeks), Usual Care (4 weeks), Washout Period (4 weeks); Device · Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 75 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: ME/CFS, ME/CFS Following EBV-associated Infectious Mononucleosis, ME/CFS Following COVID-19, Chronic Fatigue, Chronic Fatigue Syndrome (CFS), Brain Fog, Cognitive Impairment, Cognitive Dysfunction
Interventions: Processing Speed Training, In-session Instrumental Activities of Daily Living Training, Transfer Package, Follow Up Phone Calls, Trans-auricular Vagus Nerve Stimulation: High Intensity, In-session Brain Health Training, Reaction Time Training, Trans-auricular Vagus Nerve Stimulation: Low Intensity; Behavioral · Procedure
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Obstructive Sleep Apnea
Interventions: Therapeutic HGNS, Subtherapeutic 'Sham' HGNS; Device
Lead sponsor: University of Pennsylvania; Other
Eligibility: 22 Years and older
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Obstructive Sleep Apnea, OSA, Sleep Apnea
Interventions: Dimethyl fumarate, Placebo; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 65 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Delayed Sleep Phase Syndrome
Interventions: Increase morning bright light, Decrease evening blue light, Sleep Scheduling, Monitor sleep, mood, and substance use; Other · Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 13 Years to 15 Years
Enrollment: 115 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: MCI, Aging
Interventions: MediTrain, wrist worn multi-sensor watches, Sleep monitor; Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 60 Years to 85 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Sleep
Interventions: Increase sleep by 90 minutes, Decrease sleep by 90 minutes; Behavioral
Lead sponsor: Danisco; Industry
Eligibility: 20 Years to 40 Years
Enrollment: 174 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 3
States / cities: Miami, Florida • Boston, Massachusetts • Garden City, New York

Conditions: Knee Osteoarthritis, Obese, Depression
Interventions: Fisetin, GetHealthy-OA mind-body program, Placebo oral capsule, Health education booklet; Drug · Behavioral
Lead sponsor: Cale Andrew Jacobs, PhD; Other
Eligibility: 40 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 2
States / cities: Lexington, Kentucky

Conditions: Sleep Deprivation, Insufficient Sleep Syndrome, Sleep Wake Disorders
Interventions: Increased sleep duration; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 35 Years
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Salt Lake City, Utah

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Computerized Intervention for Loneliness

Characteristics of Sleep Patterns in Young Adults With and Without Insomnia

A Multi-level Life-span Characterization of Adult-depression and Effects of Medication and Exercise

Simulated Dawn Med Students

Treating Nocturnal Hypertension and Nocturia in African American Men

Cognitive Behavioral Therapy to Increase CPAP Adherence in Veterans With PTSD

Extension Family Lifestyle Intervention Project (E-FLIP for Kids)

Nuestro Sueno: Cultural Adaptation of a Couples Intervention to Improve PAP Adherence and Sleep Health Among Latino Couples With Implications for Alzheimer's Disease Risk

Deep Sleep in Older Adults

Intern Health Study 2025

Guiding Aging Long-Term Opioid Therapy Users Into Safer Use Patterns

Taxi STEP (Social Networks, Technology, and Exercise Through Pedometers)

A Phase 3 Study to Evaluate the Efficacy and Safety of TNX-102 SL Taken Daily in Patients With Fibromyalgia

Mindfulness Surgical Pain Outcomes

Circadian Amplification in Diabetic Retinopathy

Positive Airway Pressure for the Treatment of Asthma

ME/CFS Brain Fog: Cognitive Rehabilitation Trial

Hypoglossal Nerve Stimulation on Cardiovascular Outcomes

Dimethyl Fumarate for Obstructive Sleep Apnea

Experimental Manipulation of Sleep and Circadian Rhythms and the Role Played on Reward Function in Teens

Studying the Effects of Digital Interventions on Cognition, Wellbeing, Stress, and Sleep in Older Adults

Night Owl Sleep Study: The Effect of Sleep on Fecal Microbiota

GetHealthy-OA: A Program to Improve Pain and Function for Patients With Knee Osteoarthritis, Obesity, and Depression

Biomarkers of Increased Free Living Sleep Time