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Showing 1–24 of 31 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Increase water consumption Clear all
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Hydration on Gut Health and Thinking

NCT05315531
View directory record Official record
Conditions
Dehydration, Cognitive Change, Gastrointestinal Microbiota
Interventions
Water Intake
Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
19 Years to 50 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 10, 2024 · Synced Sep 11, 2026, 4:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Three-Group Study to Examine the Efficacy of the Air up® Drinking System at Improving Hydration and Associated Health Outcomes

NCT06290479
View directory record Official record
Conditions
Water Intake
Interventions
Air Up® Peach Pod, Air Up® Orangeade Pod
Dietary Supplement
Lead sponsor
air up GmbH
Industry
Eligibility
18 Years to 50 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Sep 11, 2026, 4:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CommitFit App to Facilitate Health Behavior Change in Clinic Adolescents

NCT06985251
View directory record Official record
Conditions
Overweight Adolescents
Interventions
gamified mHealth lifestyle app, Attention Control, gamified mHealth app with financial incentives
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
13 Years to 15 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Sep 11, 2026, 4:01 PM EDT
Completed Not applicable Interventional Results available

Orthostatic Hypotension Treatment on Rehab Unit

NCT01030874
View directory record Official record
Conditions
Orthostatic Hypotension, Falls
Interventions
Medication review, Nutrition/Salt intake, Education, Exercise, Drug Recommendations
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 99 Years
Enrollment
356 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 30, 2021 · Synced Sep 11, 2026, 4:01 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Thirst for Knowledge

NCT07670767
View directory record Official record
Conditions
Geriatric Population
Interventions
Education with a regular hydration opportunity
Behavioral
Lead sponsor
Duquesne University
Other
Eligibility
60 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Cornwall, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 11, 2026, 4:01 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Think AHEAD (A Healthy Eating And Drinking) Study

NCT01044134
View directory record Official record
Conditions
Obesity
Interventions
Dietary counseling
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 17 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 28, 2015 · Synced Sep 11, 2026, 4:01 PM EDT
Terminated Phase 2 Interventional Results available

Urea for Chronic Hyponatremia

NCT04588207
View directory record Official record
Conditions
Hyponatremia, Inappropriate ADH Syndrome
Interventions
Urea
Drug
Lead sponsor
Helbert Rondon Berrios, MD, MS
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 19, 2024 · Synced Sep 11, 2026, 4:01 PM EDT
Recruiting Not applicable Interventional

Developing a Digital Intervention for Adolescent Nonsuicidal Self-injury

NCT07224165
View directory record Official record
Conditions
Nonsuicidal Self-injury, Depression, Anxiety
Interventions
App-based digital mental health intervention for adolescent NSSI, App-based delivery of healthy living psychoeducational materials
Device
Lead sponsor
Northwestern University
Other
Eligibility
14 Years to 18 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 11, 2026, 4:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

INDIGO-2: The Effect of High Water Intake on Glucose Regulation in Low-drinkers

NCT04076995
View directory record Official record
Conditions
Dehydration, Diabetes Mellitus, Type 2
Interventions
Water Intake
Other
Lead sponsor
Arizona State University
Other
Eligibility
30 Years to 55 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 10, 2020 · Synced Sep 11, 2026, 4:01 PM EDT
Completed Not applicable Interventional Results available

Prevention of Urinary Stones With Hydration

NCT03244189
View directory record Official record
Conditions
Urinary Stones
Interventions
Fluid prescription, Financial incentive, Structured Problem Solving
Behavioral
Lead sponsor
Duke University
Other
Eligibility
12 Years and older
Enrollment
1,658 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
8
States / cities
Rochester, Minnesota • St Louis, Missouri • Cleveland, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 11, 2026, 4:01 PM EDT
Completed Not applicable Interventional

A Clinical Trial of Water Therapy for Autosomal Dominant Polycystic Kidney Disease

NCT03102632
View directory record Official record
Conditions
Autosomal Dominant Polycystic Kidney
Interventions
High Water Intake
Other
Lead sponsor
The Rogosin Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 18, 2023 · Synced Sep 11, 2026, 4:01 PM EDT
Completed Not applicable Interventional

Increasing Water Access and Appeal in Community Recreation Centers

NCT03637465
View directory record Official record
Conditions
Health Behavior
Interventions
Hydrate Philly
Behavioral
Lead sponsor
Philadelphia Department of Public Health
Government
Eligibility
3 Years to 100 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 1, 2019 · Synced Sep 11, 2026, 4:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility of Using sipIT Tools to Increase Compliance With Fluid Consumption Guidelines in Urolithiasis-Prone Subjects

NCT03787615
View directory record Official record
Conditions
Urolithiasis
Interventions
sipIT tools
Device
Lead sponsor
Penn State University
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 16, 2021 · Synced Sep 11, 2026, 4:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Water Intervention for Thinking in Kids (WITiKids ) Study

NCT02816450
View directory record Official record
Conditions
Low Fluid Intake, Chronic
Interventions
Water Intake
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
9 Years to 10 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 30, 2018 · Synced Sep 11, 2026, 4:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Computer Based Intervention for Type 2 Diabetes in Youth

NCT00570466
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Video Games, Web and DVD knowledge
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
10 Years to 12 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 26, 2017 · Synced Sep 11, 2026, 4:01 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Aldosterone & Sodium Regulation in Postural Tachycardia Syndrome - Screening

NCT01783288
View directory record Official record
Conditions
Postural Tachycardia Syndrome
Interventions
Autonomic Function Testing, Posture Study, Measurement of Total Blood Volume, Exercise Capacity Test
Other · Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Sep 11, 2026, 4:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Blueberry Enhances Activity and Cognition Through Increased Vascular Efficiency

NCT04049162
View directory record Official record
Conditions
Sedentary Lifestyle, Blood Pressure, Arterial Stiffness, Overweight and Obesity
Interventions
Blueberry Plus Exercise (BB-EX), Blueberry Placebo Plus Exercise (P-EX)
Dietary Supplement
Lead sponsor
Duke University
Other
Eligibility
60 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 19, 2023 · Synced Sep 11, 2026, 4:01 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Cluster Randomized Trial of the H2GO! Program

NCT04265794
View directory record Official record
Conditions
Childhood Obesity
Interventions
H2GO!
Behavioral
Lead sponsor
Boston University
Other
Eligibility
9 Years and older
Enrollment
824 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2025 · Synced Sep 11, 2026, 4:01 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Efficacy of a Smart Water Bottle Intervention to Increase Fluid Consumption in College Students

NCT06259799
View directory record Official record
Conditions
Dehydration
Interventions
Smart Water Bottle
Behavioral
Lead sponsor
Kennesaw State University
Other
Eligibility
18 Years to 35 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Kennesaw, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 1, 2025 · Synced Sep 11, 2026, 4:01 PM EDT
Completed Not applicable Interventional

Study to Warm Up and Cool Down Recreationally Active Males Using Different Protocols.

NCT06874023
View directory record Official record
Conditions
Heat Acclimation and Thermotolerance
Interventions
Passive heating in hot conditions, Active heating + passive heating in hot conditions, Active heating in hot conditions, Active heating at room temperature, Cool vest, Damp neck towel combined with arm cool water immersion, Combination of cooling interventions, Control in thermoneutral room without cooling
Other
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 12, 2025 · Synced Sep 11, 2026, 4:01 PM EDT
Completed Phase 4 Interventional

Empiric Versus Selective Prevention Strategies for Kidney Stone Disease

NCT05365477
View directory record Official record
Conditions
Kidney Stones, Nephrolithiasis
Interventions
Empiric Therapy: Diet, Empiric Therapy: Drug, Selective Therapy: Diet, Selective Therapy: Drug
Behavioral · Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 11, 2026, 4:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Text Message Program to Improve Eating Behaviors Among African Americans in New Orleans

NCT03913871
View directory record Official record
Conditions
Diet Habit, Health Behavior, Health Knowledge, Attitudes, Practice
Interventions
Texts to support healthy eating, Texts to support physical activity
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
25 Years and older · Female only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated May 6, 2019 · Synced Sep 11, 2026, 4:01 PM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

Gender Differences in the Metabolic Effects of Uric Acid

NCT03076684
View directory record Official record
Conditions
Hyperuricemia
Interventions
low-fructose diet, Allopurinol
Other · Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
40 Years to 70 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Sep 11, 2026, 4:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of Adequate Water Intake on Exercise Performance and Mood in Women and Men

NCT05033665
View directory record Official record
Conditions
Dehydration, Mood
Interventions
Increase water consumption, Maintain adequate water consumption
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 35 Years
Enrollment
217 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 23, 2023 · Synced Sep 11, 2026, 4:01 PM EDT