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Showing 1–24 of 34 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Major Depressive Disorder
Interventions
Tocilizumab, Placebo, Whole-Body Hyperthermia
Drug · Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Terminated Not applicable Interventional Accepts healthy volunteers

Whole Body Hyperthermia & Combat-Related Posttraumatic Stress Disorder (PTSD)

NCT02077972
Conditions
Post Traumatic Stress Disorder (PTSD)
Interventions
High intensity whole-body infrared heating
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Tucson, Arizona
Conditions
Covid19, Acute Respiratory Distress Syndrome, Bacterial Sepsis, Bacterial Infections
Interventions
BVA-100, Transpulmonary Thermodilution (TPTD), Sublingual Microcirculation
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 95 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
3
States / cities
Bethesda, Maryland • New York, New York • Winston-Salem, North Carolina
Recruiting Not applicable Interventional Accepts healthy volunteers

Microbiome Sampling During Endurance Exercise

NCT06903806
Conditions
Healthy, Exercise-Induced Lactic Acidemia
Interventions
Treadmill Exercise, Cooling Gloves, Microbiome Capsule
Other · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Stanford, California
Terminated Not applicable Interventional Accepts healthy volunteers

Enhancing Psychotherapy for Mood Disorders With Whole Body Hyperthermia

NCT02021149
Conditions
Major Depressive Disorder
Interventions
High intensity whole-body infrared heating, Psychotherapy, Questionnaires, Low intensity whole-body infrared heating
Device · Behavioral · Other
Lead sponsor
Charles (Chuck) Raison
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Tucson, Arizona
Conditions
Urinary Stone
Interventions
6Fr Percuflex ureteral stents, 6Fr Tria ureteral stents, 4.8Fr Tria ureteral stents, 4.8Fr Percuflex ureteral stents
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 89 Years
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Heat Acclimation and Thermotolerance
Interventions
Passive heating in hot conditions, Active heating + passive heating in hot conditions, Active heating in hot conditions, Active heating at room temperature, Cool vest, Damp neck towel combined with arm cool water immersion, Combination of cooling interventions, Control in thermoneutral room without cooling
Other
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Tempe, Arizona
Conditions
Bone Marrow Transplant
Interventions
BioIntellisense BioSticker
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Aurora, Colorado
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Does Vitamin C Increase the Body Heat Generated By The Nervous System?

NCT07341308
Conditions
Metabolism Changes, Vitamin D
Interventions
Vitamin C
Other
Lead sponsor
Colorado State University
Other
Eligibility
18 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Fort Collins, Colorado
Recruiting Not applicable Interventional

Sauna for Long Covid

NCT05931497
Conditions
Long COVID
Interventions
whole body hyperthermia
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Brown Adipose Tissue Activation on Insulin Sensitivity in Humans

NCT01791114
Conditions
Insulin Sensitivity, Obesity
Interventions
Cold exposure, Cold exposure plus propranolol, Thermoneutral Conditions, Cold water consumption, Tepid water consumption, Exercise, Meal consumption
Other
Lead sponsor
Rutgers University
Other
Eligibility
18 Years to 75 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Galveston, Texas
Conditions
Hypoxic-Ischemic Encephalopathy Mild, Neonatal Encephalopathy
Interventions
Therapeutic Hypothermia, Normothermia
Other
Lead sponsor
Stanford University
Other
Eligibility
Up to 6 Hours
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
5
States / cities
Loma Linda, California • Oakland, California • Orange, California + 2 more
Conditions
Pain, Chronic
Interventions
Float-REST, Nappod
Other
Lead sponsor
West Virginia University
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Morgantown, West Virginia
Completed No phase listed Observational Accepts healthy volunteers

Work-Related Effects of Heat, Activity, and Fat in Middle Aged Men

NCT02532725
Conditions
Obesity, Gender, Problem of Aging
Interventions
Cardiopulmonary Exercise Stress Test, Climatic-Controlled Cardiopulmonary Exercise Stress Test, Body Composition Evaluation, Pre-Exercise Risk Assessment
Procedure
Lead sponsor
Freeman-Sheldon Research Group, Inc.
Other
Eligibility
35 Years to 55 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1972
U.S. locations
1
States / cities
Buckhannon, West Virginia
Terminated Not applicable Interventional Results available

Perioperative Active Warming Techniques in Colorectal Surgeries

NCT00913978
Conditions
Normothermia
Interventions
Group 1: VitaHeat, Group 2: Bair Hugger
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Chicago, Illinois
Conditions
Breast Cancer
Interventions
ThermoDox in combination with Microwave Hyperthermia (heat)
Drug
Lead sponsor
Imunon
Industry
Eligibility
18 Years and older · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
6
States / cities
San Francisco, California • Newnan, Georgia • Baltimore, Maryland + 3 more
Conditions
Sleep Quality
Interventions
Simulated Flotation Therapy, Traditional Float-REST Therapy
Other
Lead sponsor
West Virginia University
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Morgantown, West Virginia
Conditions
SCI - Spinal Cord Injury
Interventions
HEAT - Passive Heat Therapy, Sham (No Treatment)
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 60 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
San Antonio, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Chronic Heat Therapy for Improving Vascular Health

NCT02518399
Conditions
Cardiovascular Diseases
Interventions
Heat therapy, Thermoneutral water immersion
Other
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Eugene, Oregon
Conditions
PAD
Interventions
Without Heating, Warm Bath, Neutral Bath, Heating Suit, Lower limb warm water immersion, Gardner walking protocol
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
21 Years to 85 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Hershey, Pennsylvania
Conditions
Acute Respiratory Failure
Interventions
Noninvasive positive pressure ventilation (NIPPV), Vapotherm
Device
Lead sponsor
Vapotherm, Inc.
Industry
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
5
States / cities
Athens, Georgia • Florence, South Carolina • Chattanooga, Tennessee + 2 more
Withdrawn Not applicable Interventional Accepts healthy volunteers

Whole Body Hyperthermia (WBH) as a Rapid Treatment for Fibromyalgia

NCT02332694
Conditions
Fibromyalgia
Interventions
The Whole Body Hyperthermia system uses water-filtered infrared-A (wIRA) heat radiation
Device
Lead sponsor
Charles (Chuck) Raison
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2015
U.S. locations
1
States / cities
Tucson, Arizona
Completed Not applicable Interventional Accepts healthy volunteers

The Brain on Whole Body Hyperthermia: A Neuroimaging Study

NCT02062840
Conditions
Major Depression
Interventions
High intensity whole-body infrared heating, Low intensity whole-body infrared heating, Functional Magnetic Resonance Imaging (fMRI) and electrocardiogram (EKG), Questionnaires
Device · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 30 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Tucson, Arizona
Completed Not applicable Interventional Accepts healthy volunteers

Whole Body Hyperthermia and Major Depression (MDD)

NCT01625546
Conditions
Depressive Disorder, Major
Interventions
Whole Body Hyperthermia system
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Tucson, Arizona