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Showing 1–24 of 163 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Indocyanine green Clear all
Completed Phase 2 Interventional Results available

Ranibizumab as Adjuvant Therapy for the Treatment of Choroidal Melanoma (Cohort 2)

NCT01251978
View directory record Official record
Conditions
Choroidal Melanoma
Interventions
Ranibizumab 2 mg, 0.5 mg Ranibizumab
Drug
Lead sponsor
New England Retina Associates
Other
Eligibility
50 Years to 90 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Hamden, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 18, 2016 · Synced Sep 3, 2026, 3:43 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

SPY Fluorescence Imaging Systems and Indocyanine Green to Determine the Percentage of Successful Critical Anatomy Recognition in Laparoscopic Cholecystectomy Surgeries.

NCT05006950
View directory record Official record
Conditions
Cholecystitis
Interventions
Stryker1688 Fluorescence imaging system
Device
Lead sponsor
Stryker Endoscopy
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Annapolis, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 18, 2022 · Synced Sep 3, 2026, 3:43 PM EDT
Completed Phase 2Phase 3 Interventional Results available

A Study Comparing Green Fluorescent Dye and Radioactive Dye for Sentinel Lymph Node Biopsy in Pediatric Cancers

NCT02910726
View directory record Official record
Conditions
Pediatric Patients With Solid Tumors
Interventions
Sentinel Lymph Node Biopsy, indocyanine green (ICG)
Procedure · Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Up to 30 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
3
States / cities
New York, New York • Memphis, Tennessee • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 4, 2022 · Synced Sep 3, 2026, 3:43 PM EDT
Completed No phase listed Observational

Intraoperative Fluorescence With Augmented Reality

NCT03888014
View directory record Official record
Conditions
Vascular; Lesion, Central Nervous System, Brain Tumor, Cerebral Aneurysm, Cerebral AVM
Interventions
GLOW800, indocyanine green (ICG)
Device · Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 17, 2023 · Synced Sep 3, 2026, 3:43 PM EDT
Completed Not applicable Interventional

Intravital Microscopy in Identifying Tumor Vessels in Patients With Stage IB-IIIC Melanoma Undergoing Sentinel Lymph Node Biopsy

NCT02857374
View directory record Official record
Conditions
Stage IB Skin Melanoma, Stage IIA Skin Melanoma, Stage IIB Skin Melanoma, Stage IIC Skin Melanoma, Stage IIIA Skin Melanoma, Stage IIIB Skin Melanoma, Stage IIIC Skin Melanoma
Interventions
Diagnostic Microscopy, Fluorescein Sodium Injection, Laboratory Biomarker Analysis, Sentinel Lymph Node Biopsy
Procedure · Drug · Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2022 · Synced Sep 3, 2026, 3:43 PM EDT
Completed Not applicable Interventional Results available

Study to Assess Perfusion and Patient Satisfaction in Nipple-Areola Mastectomy With Immediate Reconstruction

NCT01969448
View directory record Official record
Conditions
Ductal Carcinoma in Situ - Category, Breast Cancer, Prophylactic Mastectomy
Interventions
Inframammary Fold Incision or Lateral Radial Incision, Lateral Radial Incision, Inframammary Fold Incision, Laser-assisted fluorescence angiography, Indocyanine Green
Procedure · Device · Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 17, 2018 · Synced Sep 3, 2026, 3:43 PM EDT
Completed No phase listed Observational Results available

ICG Fluorescence Imaging in Lower Extremity Amputation Patients

NCT04250558
View directory record Official record
Conditions
Trauma Injury
Interventions
Lower Extremity Amputation
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 3, 2026, 3:43 PM EDT
Completed Phase 2 Interventional Results available

Low Dose ICG for Biliary Tract and Tumor Imaging

NCT04942665
View directory record Official record
Conditions
Cholecystitis, Hepatocellular Carcinoma, Liver Metastases
Interventions
Indocyanine green, PINPOINT Endoscopic Fluorescence
Drug · Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 29, 2023 · Synced Sep 3, 2026, 3:43 PM EDT
Completed Phase 1 Interventional

Imiquimod and Laser Therapy With or Without a Green Dye in Treating Patients With Stage III or Stage IV Melanoma That Has Spread to Other Parts of the Skin

NCT00453050
View directory record Official record
Conditions
Melanoma (Skin), Metastatic Cancer
Interventions
imiquimod, indocyanine green solution, flow cytometry, immunologic technique, laboratory biomarker analysis
Drug · Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 5, 2015 · Synced Sep 3, 2026, 3:43 PM EDT
Completed No phase listed Observational

Assessment Of Liver Function in Patients Undergoing Hepatic Irradiation

NCT01519219
View directory record Official record
Conditions
Hepatic Irradiation
Interventions
Hepatic Irradiation
Radiation
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
18 Years and older
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 19, 2020 · Synced Sep 3, 2026, 3:43 PM EDT
Completed Not applicable Interventional

Surrogate Markers of Portal Pressure

NCT02508298
View directory record Official record
Conditions
Portal Hypertension, Cirrhosis
Interventions
HVPG, Indocyanine Green Retention test, Liver stiffness measurement, Spleen stiffness measurement
Procedure · Drug · Device
Lead sponsor
VA Connecticut Healthcare System
Federal
Eligibility
18 Years to 85 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
2
States / cities
New Haven, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 24, 2019 · Synced Sep 3, 2026, 3:43 PM EDT
Enrolling by invitation Phase 1Phase 2 Interventional

Evaluation of Lymphatic Response to Physiotherapy in Patients With Swelling Associated With Superficial Venous Disease

NCT07165340
View directory record Official record
Conditions
Chronic Venous Disease
Interventions
Indocyanine Green near infrared fluorescence imaging, advanced pneumatic compression, Duplex ultrasound, compression wrap
Combination Product · Device · Diagnostic Test
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Sep 3, 2026, 3:43 PM EDT
Recruiting Phase 1Phase 2 Interventional

Use of Indocyanine Green (ICG) for the Diagnosis of Biliary Atresia

NCT07513038
View directory record Official record
Conditions
Biliary Atresia
Interventions
Indocyanine Green (ICG)
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
0 Days to 3 Months
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Sep 3, 2026, 3:43 PM EDT
Active, not recruiting No phase listed Observational

Fluorescence-based Detection of Inflammation and Necrosis to Inform Surgical Decision-making and Enhance Outcomes

NCT05593523
View directory record Official record
Conditions
Burn Wound
Interventions
Indocyanine green (ICG), Clinical Fluorescence Imaging Device
Drug · Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 3, 2026, 3:43 PM EDT
Completed Phase 2 Interventional Results available

A Study to Evaluate ONM100, an Intraoperative Fluor Imaging Agent for the Detection of Peri Mets

NCT04950166
View directory record Official record
Conditions
Peritoneal Carcinomatosis
Interventions
pegsitacianine
Drug
Lead sponsor
OncoNano Medicine, Inc.
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
5
States / cities
Winston-Salem, North Carolina • Columbus, Ohio • Philadelphia, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2024 · Synced Sep 3, 2026, 3:43 PM EDT
Completed Phase 2 Interventional Results available

A Study of Individualized Stereotactic Body Radiation Therapy (SBRT) for Intrahepatic Cancer

NCT01522937
View directory record Official record
Conditions
Liver Cancer, Hepatocellular Cancer
Interventions
individualized Stereotactic Body Radiation Therapy (SBRT)
Radiation
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 8, 2017 · Synced Sep 3, 2026, 3:43 PM EDT
Completed Phase 4 Interventional Results available

Effect of Exercise on Indocyanine Green (ICG) Lymphography Imaging

NCT03584633
View directory record Official record
Conditions
Lymphedema
Interventions
Indocyanine Green
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 26, 2024 · Synced Sep 3, 2026, 3:43 PM EDT
Completed No phase listed Observational

Detection of Cerebral Ischemia With a Noninvasive Neurometabolic Optical Monitor

NCT02983786
View directory record Official record
Conditions
Traumatic Brain Injury, Ischemic Stroke, Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Acute Anoxic Encephalopathy
Interventions
Indocyanine Green
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 1, 2022 · Synced Sep 3, 2026, 3:43 PM EDT
Completed Not applicable Interventional Results available

Near Infrared Fluorescence Cholangiography (NIRF-C) During Cholecystectomy

NCT02070640
View directory record Official record
Conditions
Cholecystitis
Interventions
Injection of indocyanine green (ICG), Near Infrared Cholangiography Fluorescence (NIRF-C)
Drug · Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 89 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 20, 2015 · Synced Sep 3, 2026, 3:43 PM EDT
Recruiting No phase listed Observational

Use Of Indocyanine Green In Pancreas Surgery

NCT06084013
View directory record Official record
Conditions
Pancreatic Carcinoma
Interventions
Non-Interventional Study
Other
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 3, 2026, 3:43 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

The Use of Near-Infrared Fluorescence Cholangiography With Indocyanine Green (ICG) in the Work Up of Neonatal Cholestasis

NCT07250854
View directory record Official record
Conditions
Biliary Atresia, Kasai, Cholestasis in Newborn, Cholestasis in Newborn Infant
Interventions
Indocyanine Green
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
2 Weeks to 4 Months
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 3, 2026, 3:43 PM EDT
Recruiting Phase 1 Interventional

Imaging of Lymphatic Vessels in People With Rheumatoid Arthritis (RA)

NCT05197530
View directory record Official record
Conditions
Rheumatoid Arthritis
Interventions
Indocyanine green, MultiSpectral Imaging System
Drug · Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Sep 3, 2026, 3:43 PM EDT
Withdrawn Phase 4 Interventional

A Study to Evaluate Indocyanine Green Lymphangiography to Improve Lymphadenectomy in Gastric Cancer Patients

NCT04591028
View directory record Official record
Conditions
Gastric Cancer
Interventions
Indocyanine green
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 18, 2023 · Synced Sep 3, 2026, 3:43 PM EDT
Terminated Phase 2 Interventional Results available

Sentinel and/or Axillary Lymph Node Biopsy With or Without Axillary Reverse Mapping in Reducing Incidence and Severity of Arm Lymphedema in Stage 0-2 Patients.

NCT01276054
View directory record Official record
Conditions
Lymphedema, Recurrent Breast Cancer, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage II Breast Cancer
Interventions
technetium Tc 99m sulfur colloid, methylene blue, indocyanine green solution, sentinel lymph node biopsy, axillary lymph node biopsy, bioimpedance spectroscopy, quality-of-life assessment, lymphedema management
Radiation · Drug · Procedure + 1 more
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 31, 2014 · Synced Sep 3, 2026, 3:43 PM EDT