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ClinicalTrials.gov public records Last synced Sep 29, 2026, 4:41 PM EDT

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Showing 1–24 of 135 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Indocyanine green (ICG) Clear all
Active, not recruiting Phase 3 Interventional

A Study of Intra-operative Imaging in Women With Ovarian Cancer

NCT04878094
View directory record Official record
Conditions
Ovarian Cancer, Ovarian Carcinoma
Interventions
Intravenous Indocyanine Green/ICG injection, PINPOINT endoscopic fluorescence imaging system, Endoscopy
Diagnostic Test
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Female only
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
9
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 29, 2026, 4:41 PM EDT
Active, not recruiting Phase 1 Interventional

Assessing Impact of Early Physiotherapy on Lymphatic Dysfunction in Head and Neck Cancer Survivorship

NCT05937269
View directory record Official record
Conditions
Lymphedema of Face, Head and Neck Cancer
Interventions
Near-infrared fluorescence lymphatic imaging, advanced pneumatic compression therapy
Combination Product · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 29, 2026, 4:41 PM EDT
Completed No phase listed Observational

Detection of Cerebral Ischemia With a Noninvasive Neurometabolic Optical Monitor

NCT02983786
View directory record Official record
Conditions
Traumatic Brain Injury, Ischemic Stroke, Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Acute Anoxic Encephalopathy
Interventions
Indocyanine Green
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 1, 2022 · Synced Sep 29, 2026, 4:41 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

ObseRvation of PeripHEral rEtinal Morphology in Normals

NCT02091700
View directory record Official record
Conditions
Healthy
Interventions
Indocyanine Green ICG
Other
Lead sponsor
Optos, PLC
Industry
Eligibility
20 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 12, 2017 · Synced Sep 29, 2026, 4:41 PM EDT
Completed No phase listed Observational

Evaluation of the Association Between Genetic Load and Response to Anti-VEGF Therapy in AMD Patients

NCT01644513
View directory record Official record
Conditions
Age Related Macular Degeneration
Interventions
Not listed
Lead sponsor
Sequenom, Inc.
Industry
Eligibility
55 Years and older
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 11, 2013 · Synced Sep 29, 2026, 4:41 PM EDT
Not yet recruiting Phase 1 Interventional

Magnetic Sentinel Lymph Node Mapping in Gastric Cancer

NCT05038098
View directory record Official record
Conditions
Gastric Adenocarcinoma
Interventions
Gastrectomy, Indocyanine Green, Iron Conjugated Polymers in Saline Suspension
Procedure · Drug · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 29, 2026, 4:41 PM EDT
Recruiting Phase 3 Interventional

Sentinel Node Biopsy in Endometrial Cancer

NCT04073706
View directory record Official record
Conditions
Endometrial Cancer Stage I, Sentinel Lymph Node, Surgery
Interventions
TH BSO with SNB Note: If participants (≤45yo), Grade 1 endometrial adenocarcinoma with myometrial invasion <50%, wish to retain their ovaries a BSO may be omitted, TH BSO without retroperitoneal node dissection Note: If participants (≤45yo), Grade 1 endometrial adenocarcinoma with myometrial invasion <50%, wish to retain their ovaries a BSO may be omitted
Procedure
Lead sponsor
Queensland Centre for Gynaecological Cancer
Government
Eligibility
18 Years and older · Female only
Enrollment
760 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2031
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 29, 2026, 4:41 PM EDT
Completed Phase 1 Interventional

Potential Use of Indocyanine Green as a Fluorescent Agent for Definition of Surgical Margins in Cancer

NCT01884584
View directory record Official record
Conditions
Malignant Neoplasm
Interventions
Indocyanine green (ICG)
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 8, 2017 · Synced Sep 29, 2026, 4:41 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Feasibility and Utility of Artificial Intelligence (AI) / Machine Learning (ML) - Driven Advanced Intraoperative Visualization and Identification of Critical Anatomic Structures and Procedural Phases in Laparoscopic Cholecystectomy

NCT05775133
View directory record Official record
Conditions
Cholecystitis, Cholelithiasis, Biliary Dyskinesia
Interventions
ICG
Device
Lead sponsor
Activ Surgical
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 20, 2024 · Synced Sep 29, 2026, 4:41 PM EDT
Completed Phase 4 Interventional Results available

Effect of Exercise on Indocyanine Green (ICG) Lymphography Imaging

NCT03584633
View directory record Official record
Conditions
Lymphedema
Interventions
Indocyanine Green
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 26, 2024 · Synced Sep 29, 2026, 4:41 PM EDT
Recruiting No phase listed Observational

Real-Time Diagnosis of Life-Threatening Necrotizing Soft Tissue Infections (NSTI) Using Indocyanine Green (ICG) Kinetic Modeling

NCT06877793
View directory record Official record
Conditions
Necrotizing Fascitis
Interventions
Administration of indocyanine green (ICG) and fluorescence imaging
Diagnostic Test
Lead sponsor
Eric R. Henderson
Other
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
8
States / cities
Los Angeles, California • Stanford, California • Atlanta, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Sep 29, 2026, 4:41 PM EDT
Completed Not applicable Interventional

Indocyanine Green Lymphangiography in Identifying Thoracic Duct During Neck Surgery

NCT03532581
View directory record Official record
Conditions
Neck Dissection, Radical Lymph Node Dissection
Interventions
Indocyanine Green Solution, Lymphangiography
Other · Procedure
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 15, 2024 · Synced Sep 29, 2026, 4:41 PM EDT
Active, not recruiting No phase listed Observational

Fluorescence-based Detection of Inflammation and Necrosis to Inform Surgical Decision-making and Enhance Outcomes

NCT05593523
View directory record Official record
Conditions
Burn Wound
Interventions
Indocyanine green (ICG), Clinical Fluorescence Imaging Device
Drug · Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 29, 2026, 4:41 PM EDT
Completed Not applicable Interventional Results available

Lymph Node Mapping Using Indocyanine Green Solution in Diagnosing Patients With Malignant Melanoma

NCT01898403
View directory record Official record
Conditions
Recurrent Melanoma
Interventions
Indocyanine green solution, Isosulfan blue (ISB), Lymphoscintigraphy with 99-technetium (99Tc) sulfur colloid (TSC)
Drug · Diagnostic Test
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 23, 2017 · Synced Sep 29, 2026, 4:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Indocyanine Green Tissue Perfusion Monitoring

NCT02978560
View directory record Official record
Conditions
Regional Blood Flow, Wound Heal
Interventions
fluorescence-mediated photoplethysmography
Diagnostic Test
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Towson, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Sep 29, 2026, 4:41 PM EDT
Active, not recruiting Not applicable Interventional

Study of Near-Infrared Imaging With Indocyanine Green for Detection of Sentinel Lymph Nodes in People With Vulvar Cancer

NCT06127836
View directory record Official record
Conditions
Vulvar Cancer
Interventions
ICG guided sentinel lymph node biopsy
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
8
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 5 more
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Sep 29, 2026, 4:41 PM EDT
Completed Early Phase 1 Interventional

A Pilot Study of Optical Molecular Imaging for Percutaneous Biopsy of Hepatocellular Carcinoma Using Indocyanine Green

NCT01962649
View directory record Official record
Conditions
Hepatocellular Carcinoma
Interventions
ICG, Optical molecular imaging
Biological · Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2018 · Synced Sep 29, 2026, 4:41 PM EDT
Terminated Phase 2 Interventional

Shave Margins in Breast Conservation Therapy

NCT02462200
View directory record Official record
Conditions
Breast Cancer, Cancer of Breast, Cancer of the Breast
Interventions
Breast-conserving surgery (BCS), Cavity shave margins (CSM), BREAST-Q Questionnaire, 3-D breast imaging, Indocyanine green, Intraoperative imaging device, Peripheral blood draw
Procedure · Behavioral · Device + 1 more
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 24, 2020 · Synced Sep 29, 2026, 4:41 PM EDT
Completed Not applicable Interventional Results available

Infrared Lymphangiography as a Method of Sentinel Node Identification

NCT02057393
View directory record Official record
Conditions
Melanoma, Sentinel Node
Interventions
Indocyanine green, Technetium99, Methylene blue
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 5, 2017 · Synced Sep 29, 2026, 4:41 PM EDT
Recruiting Early Phase 1 Interventional

Indocyanine Green (ICG) Guided Sentinel Lymph Node Mapping for Pediatric Visceral Solid Tumors

NCT05645523
View directory record Official record
Conditions
Solid Tumor
Interventions
Indocyanine Green
Drug
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
Up to 20 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
Chicago, Illinois • Pittsburgh, Pennsylvania • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 29, 2026, 4:41 PM EDT
Completed Phase 2Phase 3 Interventional Results available

A Study Comparing Green Fluorescent Dye and Radioactive Dye for Sentinel Lymph Node Biopsy in Pediatric Cancers

NCT02910726
View directory record Official record
Conditions
Pediatric Patients With Solid Tumors
Interventions
Sentinel Lymph Node Biopsy, indocyanine green (ICG)
Procedure · Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Up to 30 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
3
States / cities
New York, New York • Memphis, Tennessee • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 4, 2022 · Synced Sep 29, 2026, 4:41 PM EDT
Completed Not applicable Interventional Results available

The Use of Fluorescent Imaging for Intraoperative Cholangiogram During Laparoscopic Cholecystectomy

NCT01424215
View directory record Official record
Conditions
Cholelithiasis, Cholecystitis, Pancreatitis Biliary, Colic of Gallbladder Without Mention of Cholecystitis
Interventions
Indocyanine Green (ICG)
Drug
Lead sponsor
Maimonides Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Sep 29, 2026, 4:41 PM EDT
Recruiting Early Phase 1 Interventional

Impact of Intraoperative ICG on Functional Outc in RARP

NCT06446648
View directory record Official record
Conditions
Prostate Adenocarcinoma
Interventions
ICG
Drug
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older · Male only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Sep 29, 2026, 4:41 PM EDT
Withdrawn Phase 2 Interventional

Robotic Bronchoscopy With Cone CT and Indocyanine Green to Aid Removal of Lung Lesions in Patients With Stage I Non-small Cell Lung Cancer or Lung Metastases, REPLACING Study

NCT04987281
View directory record Official record
Conditions
Lung Non-Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Lung, Stage I Lung Cancer AJCC v8
Interventions
Computed Tomography, Indocyanine Green Solution, Therapeutic Bronchoscopy
Procedure · Drug · Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 22, 2024 · Synced Sep 29, 2026, 4:41 PM EDT