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ClinicalTrials.gov public records Last synced Nov 10, 2026, 12:38 PM EST

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Showing 1–24 of 176 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Induced Stress Clear all

Conditions: Posttraumatic Stress Disorder, Major Depressive Disorder
Interventions: Positive Processes and Transition to Health, Progressive Muscle Relaxation; Behavioral
Lead sponsor: Case Western Reserve University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 135 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 3
States / cities: Newark, Delaware • Cleveland, Ohio • Seattle, Washington

Conditions: Stress Reaction, Stress, Emotional, Stress, COVID-19 Pandemic
Interventions: Questionnaires; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 415 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Orthopedic Trauma Surgery Patients, Postoperative Pain, Opioid Use, Depression, Post-traumatic Stress Disorder (PTSD)
Interventions: Ketamine, standard general anesthesia; Drug
Lead sponsor: Texas Tech University Health Sciences Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Lubbock, Texas

Conditions: Stress (Psychology), Inflamation, Psychosocial Functioning
Interventions: Building Emotional Strength Training; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Heat Stress, Exertional, Heat Acclimation and Thermotolerance
Interventions: Exercise with Overdressing, Control Exercise; Other
Lead sponsor: United States Army Research Institute of Environmental Medicine; Federal
Eligibility: 18 Years to 45 Years
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Natick, Massachusetts

Conditions: Mitochondrial Diseases
Interventions: Trier social stress test; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: Healthy, Atopic Dermatitis
Interventions: Trier Social Stress Test (TSST), Landscape Video; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 59 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Phenylketonuria
Interventions: Kuvan, Meal Challenge; Drug · Other
Lead sponsor: Emory University; Other
Eligibility: 10 Years to 45 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Decatur, Georgia

Conditions: Induction of Labor Affected Fetus / Newborn, Cervical Ripening, Patient Satisfaction
Interventions: Outpatient Cervical Ripening, Inpatient Cervical Ripening, Foley catheter placement, Pre-Foley Questionnaire, Post-Foley Questionnaire, Fetal Non-Stress Test; Other · Procedure · Behavioral
Lead sponsor: MemorialCare Health System; Other
Eligibility: 18 Years and older · Female only
Enrollment: 94 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2025
U.S. locations: 1
States / cities: Long Beach, California

Conditions: Females, Males, Menopause, Sedentary, Healthy Participants
Interventions: Vitamin C (Ascorbic Acid); Dietary Supplement
Lead sponsor: University of Virginia; Other
Eligibility: 45 Years and older
Enrollment: 1 participant
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Post Intensive Care Syndrome, Anxiety, Depression, Posttraumatic Stress Disorder, Sleep Deprivation
Interventions: SAF-T; Behavioral
Lead sponsor: University of South Florida; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Down Syndrome, Autonomic Dysfunction
Interventions: Cold Stress, Maximal Dynamic Exercise, Isometric Handgrip Exercise with Post-Exercise Muscle Ischemia, Head-up Tilt Table Test; Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 50 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Hyperglycemia, Cardiovascular Disease
Interventions: Green Tea Concentrate; Dietary Supplement
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 30 Years · Male only
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Stress, Control Condition
Interventions: Acute Stress, Non-Stress Control Task; Behavioral
Lead sponsor: Nevada State University; Other
Eligibility: 18 Years to 35 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Henderson, Nevada

Conditions: Musculoskeletal Pain
Interventions: Pain Catastrophizing Induction; Behavioral
Lead sponsor: Beth Darnall, PhD; Other
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 93 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Inflammatory Bowel Diseases, Psychological
Interventions: Biofeedback Enhanced Treatment; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 13 Years to 18 Years
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 3
States / cities: Atlanta, Georgia

Conditions: Hypertension
Interventions: Induced Stress, Buccal Swab; Behavioral · Procedure
Lead sponsor: Augusta University; Other
Eligibility: 15 Years to 19 Years
Enrollment: 1,099 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Stroke, Chronic, Aging, Cognitive Decline, Motor Dysfunction, Neuroplasticity
Interventions: High intensity cycling, Low-intensity cycling, Health education session, Moderate Intensity Aerobic Exercise; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 85 Years
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Sepsis
Interventions: Metoclopramide, Zinc, Glutamine, Selenium, saline, sterile water, selenium, whey-protein; Drug · Dietary Supplement · Other
Lead sponsor: Michael Dean; Other
Eligibility: 12 Months to 17 Years
Enrollment: 293 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 7
States / cities: Little Rock, Arkansas • Los Angeles, California • Washington D.C., District of Columbia + 3 more

Conditions: Trauma, Posttraumatic Stress Disorder
Interventions: Trier Social Stress Test (TSST), No stress condition; Behavioral · Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 21 Years to 30 Years
Enrollment: 197 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Anxiety
Interventions: HPA, ANS stimulation, Placebo; Drug
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Smoking
Interventions: Doxazosin 4mg/day, Placebo, Doxazosin 8mg/day; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Cannabis Use Disorder
Interventions: Cannabidiol oral solution, Placebo; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 25 Years
Enrollment: 148 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Hypertension
Interventions: Self affirmation and positive affect induction vs. control; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 262 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2008
U.S. locations: 1
States / cities: New York, New York

Search by objective public record fields.

Positive Processes and Transition to Health (PATH)

COVID-19 Pandemic Induced Stress and Symptoms

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

A Mindfulness-Based Intervention to Reduce Stress Through the Cultivation of Loving-Kindness, Compassion, Joy, and Equanimity in Healthcare Professionals

Acute Exercise With Overdressing

Mitochondrial Stress, Brain Imaging, and Epigenetics

Stress-induced Scratching in Healthy and AD

Phenylketonuria, Oxidative Stress, and BH4

Patient Satisfaction During Outpatient Versus Inpatient Foley Catheter Induction of Labor

The Effects of Vitamin C on Acute-Exercise in Postmenopausal Females

Sensation Awareness Focused Training for Spouses

Exploring Sympathetic Nervous System Function in Individuals With Down Syndrome

Green Tea Confections For Managing Postprandial Hyperglycemia-Induced Vascular Endothelial Dysfunction

Disrupted Connections: The Impact of Acute Stress on Memory Integration

Pain Catastrophizing as a Cause for Systemic Inflammation

Stress in Inflammatory Bowel Disease

Evaluating the Relationship Between Inflammation, Genetics, and Stress in the Development of High Blood Pressure

AMPLIFI: Adaptive Modulation of Plasticity Through Lactate and Fitness Interventions

The CRISIS Prevention Study

Stress-induced Drinking in Emerging Adults: the Role of Trauma History

Disentangling Anxiety Sensitivity and Anxiety-induced Physiological Stress Response

Does Doxazosin Attenuate Stress-induced Smoking and Improve Clinical Outcomes?

SCORE Emerging Adult Cannabis Use & Stress

Psychosocial Determinants of Medication Adherence in Hypertensive African Americans