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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:22 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 97–120 of 177 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Induced Stress Clear all

Conditions: Stress Reaction, Stress Physiology
Interventions: Sympathetic Nervous System Activation, No-stress; Behavioral
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years to 65 Years
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Patients at Risk for Melanoma
Interventions: N-acetylcysteine, Placebo arm; Drug · Other
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Loneliness, Depression
Interventions: Mindful response to adversity brief training, Strengths-based response to adversity brief training; Behavioral
Lead sponsor: Carnegie Mellon University; Other
Eligibility: 18 Years and older
Enrollment: 114 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Hypertension
Interventions: Induced Stress, Buccal Swab; Behavioral · Procedure
Lead sponsor: Augusta University; Other
Eligibility: 15 Years to 19 Years
Enrollment: 1,099 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Alcohol Use Disorder
Interventions: Allopregnanolone, Placebos; Drug
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 50 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Cannabis Use
Interventions: Trier Social Stress Task (TSST); Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 50 Years to 80 Years
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Alcohol Use Disorder
Interventions: alcohol, Stress-Induction, PT150; Drug · Behavioral
Lead sponsor: Pop Test Oncology LLC; Industry
Eligibility: 21 Years to 55 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Healthy
Interventions: Phenytoin (brand name Dilantin), Hydrocortisone, Placebo; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 50 Years
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Major Depressive Disorder, Mood Disorders
Interventions: Rumination-Focused CBT, Relaxation-based Therapy; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 14 Years to 17 Years
Enrollment: 183 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2029
U.S. locations: 3
States / cities: Columbus, Ohio • Salt Lake City, Utah

Conditions: Stress, Eating Behavior
Interventions: Acute Laboratory Stressor, Low affect video; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 14 Years to 19 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Cocaine Dependence, Alcohol Dependence
Interventions: Placebo session 1, Aprepitant session 2, Placebo session 1, Placebo session 2; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 60 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Cigarette Smoking
Interventions: Puff Topography Biofeedback Training, Control; Behavioral
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 19 Years to 55 Years
Enrollment: 154 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Hypertrophic Obstructive Cardiomyopathy, Thoracic Aortic Dilatation, Heart Disease Caused by Ionising Radiation, Quality of Life
Interventions: QOL Survey; Other
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 70 Years
Enrollment: 380 participants
Timeline: 2019 – 2026
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Primary Brain Tumor, Brain Tumor, Recurrent
Interventions: Fluoxetine, Temozolomide; Drug
Lead sponsor: Duke University; Other
Eligibility: 24 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 4
States / cities: San Diego, California • Stanford, California • New York, New York + 1 more

Conditions: Myocardial Ischemia
Interventions: exercise; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 60 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 1997 – 2000
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Post-traumatic Stress
Interventions: Cervical Transcutaneous Vagus Nerve Stimulation (Active Comparator), Cervical Transcutaneous Vagus Nerve Stimulation (Sham Comparator); Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 21 Years to 65 Years · Male only
Enrollment: 88 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: San Diego, California

Conditions: Behavior
Interventions: Positive Emotion Induction, Neutral Emotion Induction; Behavioral
Lead sponsor: University of Denver; Other
Eligibility: 18 Years to 55 Years
Enrollment: 99 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Heat Stress Disorders
Interventions: Daily aspirin (ASA), Active cooling, Acute aspirin (ASA), Passive cooling, Daily placebo, Acute placebo; Drug · Other
Lead sponsor: Dave Hostler; Other
Eligibility: 18 Years to 49 Years
Enrollment: 124 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Peripheral Artery Disease (D058729), Oxidative Stress (D018384), Inflammation (D007249)
Interventions: PB125, Placebo, Exercise Rehabilitation; Dietary Supplement · Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 40 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Salt Lake City, Utah

Conditions: Heat Stress, Exertional, Heat Acclimation and Thermotolerance
Interventions: Exercise with Overdressing, Control Exercise; Other
Lead sponsor: United States Army Research Institute of Environmental Medicine; Federal
Eligibility: 18 Years to 45 Years
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Natick, Massachusetts

Conditions: Major Depressive Disorder
Interventions: Not listed
Lead sponsor: Mclean Hospital; Other
Eligibility: 18 Years to 25 Years
Enrollment: 251 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Pigmentation, Oxidative Stress
Interventions: Sunscreen application #1, Sunscreen application #2; Other
Lead sponsor: Kenvue Brands LLC; Industry
Eligibility: 18 Years to 60 Years · Female only
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Union, New Jersey

Conditions: Vasodilation, Arterial Stiffness
Interventions: Acetylcholine, Sodium Nitroprusside, Ascorbic Acid; Drug
Lead sponsor: Colorado State University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Fort Collins, Colorado

Conditions: Heart Disease, Ischemic Heart Disease
Interventions: apadenoson; Drug
Lead sponsor: Forest Laboratories; Industry
Eligibility: 18 Years and older
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2005
U.S. locations: 77
States / cities: Birmingham, Alabama • Huntsville, Alabama • North Little Rock, Arkansas + 69 more

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Acute Plasma Abeta Responses to Stress

Oral N-acetylcysteine for Protection of Human Nevi Against UV-induced Oxidative Stress/Damage in Vivo

Mindful Response to Adversity: A Brief Stress Resilience Training

Evaluating the Relationship Between Inflammation, Genetics, and Stress in the Development of High Blood Pressure

Effect of Allopregnanolone on Stress-induced Craving

Stress-Reactivity and Cannabis Use in Cannabis-Using Older Adults

PT150 Drug for Use in Alcohol Use Disorder

Phenytoin as a Neuroprotective Agent Against Corticosteroid-induced Functional Imaging Changes

Mechanisms of Rumination Change in Adolescent Depression

Stress Reactivity Study in Adolescents

HBPL Study of the Impact of the NK1 Antagonist Aprepitant

Puff Biofeedback to Reduce Smoking Reinforcement

A Cardiac Disease Quality of Life Study

Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT)

The Effect of Exercise Training on Mental Stress-Induced Silent Ischemia

Vagal Nerve Stimulation to Probe Inflammation and Brain in Post-traumatic Stress

Investigating the Neural Systems That Support the Beneficial Effects of Positive Emotion on Stress Regulation

Enhanced Firefighter Rehab Trial: The Role of Aspirin in Preventing Heat Stress Induced Platelet Activation

Improving Exercise Rehabilitation Efficacy Outcomes Veterans Peripheral Artery Disease

Acute Exercise With Overdressing

Sex, Hormones and Gamma-Aminobutyric Acid (GABA) in Stress Induced Anhedonia in Depression

A Study to Evaluate the Ability of Sunscreen Products to Modulate the Effects of Deep UVA +/- HEV Blue Light Induced Pigmentation and Biomarkers of Cutaneous Oxidative Stress

Targeting ER Stress in Vascular Dysfunction

A Study to Examine MPI SPECT Imaging With BMS068645 and Adenosine Compared to Coronary Angiography