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Showing 1–24 of 55 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Inguinal hernia surgery Clear all
Completed Phase 2 Interventional Results available

Efficacy, Safety and Pharmacokinetic Profile of a Collagen Bupivacaine Implant in Men After Open Mesh Herniorrhaphy

NCT00626886
View directory record Official record
Conditions
Postoperative Pain, Inguinal Hernia
Interventions
Bupivacaine Collagen Sponge, placebo collagen sponge
Drug
Lead sponsor
Innocoll
Industry
Eligibility
18 Years and older · Male only
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Anaheim, California
Source: ClinicalTrials.gov public record
Updated Jan 10, 2021 · Synced Sep 2, 2026, 11:07 AM EDT
Completed No phase listed Observational

Feasibility Study for PANDAS

NCT00754897
View directory record Official record
Conditions
Inguinal Hernia, Developmental Delay Disorders
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 3 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 15, 2009 · Synced Sep 2, 2026, 11:07 AM EDT
Active, not recruiting No phase listed Observational

Natural History of Infants With Patent Processus Vaginalis

NCT03042858
View directory record Official record
Conditions
Patent Processus Vaginalis, Inguinal Hernia
Interventions
Infants with PPV, Infants without PPV
Other
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
1 Day to 4 Months
Enrollment
801 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2036
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Sep 2, 2026, 11:07 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Phase I/II Dose-escalation Study to Evaluate Safety, PK and Efficacy of TLC590 for Postsurgical Pain Management

NCT03591146
View directory record Official record
Conditions
Inguinal Hernia
Interventions
TLC590, Naropin
Drug
Lead sponsor
Taiwan Liposome Company
Industry
Eligibility
18 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Draper, Utah
Source: ClinicalTrials.gov public record
Updated Jul 13, 2021 · Synced Sep 2, 2026, 11:07 AM EDT
Completed No phase listed Observational

A Prospective Study to Compare the Clinical Outcomes, Pain and Patient Quality of Life for Hernia Patients

NCT02715622
View directory record Official record
Conditions
Hernia, Incisional Hernia, Hernia, Inguinal, Indirect, Hernia, Inguinal, Direct, Inguinal Hernia
Interventions
Hernia repair
Procedure
Lead sponsor
Intuitive Surgical
Industry
Eligibility
18 Years and older
Enrollment
944 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
17
States / cities
Beverly Hills, California • Nashville, California • Oakland, California + 14 more
Source: ClinicalTrials.gov public record
Updated Feb 28, 2023 · Synced Sep 2, 2026, 11:07 AM EDT
Not listed Not applicable Interventional

Medial Versus Traditional Approach to US-guided TAP Blocks for Open Inguinal Hernia Repair

NCT01589796
View directory record Official record
Conditions
Abdominal Muscles/Ultrasonography, Adult, Ambulatory Surgical Procedures, Anesthetics, Local/Administration & Dosage, Ropivacaine/Administration & Dosage, Ropivacaine/Analogs & Derivatives, Hernia, Inguinal/Surgery, Humans, Nerve Block/Methods, Pain Measurement/Methods, Pain, Postoperative/Prevention & Control, Ultrasonography, Interventional
Interventions
TAP block
Procedure
Lead sponsor
Stamford Anesthesiology Services, PC
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
2
States / cities
Stamford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 1, 2012 · Synced Sep 2, 2026, 11:07 AM EDT
Withdrawn Not applicable Interventional

Laparoscopic Versus Robot-assisted Inguinal Hernia Repair: A Single Institution Randomized Controlled Trial

NCT03133533
View directory record Official record
Conditions
Hernia, Inguinal
Interventions
laparoscopic repair, robot-assisted repair
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 17, 2018 · Synced Sep 2, 2026, 11:07 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mesh Removal Versus No Mesh Removal for Chronic Groin Pain After Inguinal Hernia Repair

NCT05484635
View directory record Official record
Conditions
Chronic Groin Pain, Hernia, Inguinal
Interventions
Diagnostic laparoscopy and inguinal mesh removal, Diagnostic laparoscopy
Procedure
Lead sponsor
David Krpata
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 5, 2025 · Synced Sep 2, 2026, 11:07 AM EDT
Completed No phase listed Observational Results available

Measuring Intraabdominal Pressure, Lactic Acid, and Urine Output

NCT05070572
View directory record Official record
Conditions
Intra-Abdominal Hypertension, Inguinal Hernia
Interventions
Accuryn Monitoring System
Device
Lead sponsor
Antonios Likourezos
Other
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Timeline
2021 – 2023
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 2, 2026, 11:07 AM EDT
Completed No phase listed Observational

Quantitative Sensory Testing and Analysis of Post Inguinal Hernia Surgery Pain

NCT01534429
View directory record Official record
Conditions
Hernia
Interventions
Quantitative Sensory Testing
Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2016 · Synced Sep 2, 2026, 11:07 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Ventral or Inguinal Hernia, Robotically Repaired With OviTex Mesh

NCT04779918
View directory record Official record
Conditions
Hernia, Ventral, Hernia, Inguinal
Interventions
OviTex Reinforced Tissue Matrix
Device
Lead sponsor
Tela Bio Inc
Industry
Eligibility
21 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2029
U.S. locations
10
States / cities
Mobile, Alabama • Denver, Colorado • Destin, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 2, 2026, 11:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of a Bilateral TAP Block and Preperitoneal Instillation of Local Anesthetic for a Total Extraperitoneal (TEP) Repair

NCT02036983
View directory record Official record
Conditions
Bilateral Inguinal Hernia Repair
Interventions
Transversus abdominis plane block (TAP BLOCK), Instillation of surgical site with local anesthetic., Opioid IV medications (Control)
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 5, 2018 · Synced Sep 2, 2026, 11:07 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Transabdominal Plane (TAP) Blocks for Inguinal Hernia Repairs

NCT05672680
View directory record Official record
Conditions
Inguinal Hernia
Interventions
0.25% Bupivacaine, Placebo, TAP block
Drug · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Sep 2, 2026, 11:07 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Role of Immune System in Obesity-related Inflammation and Cardiometabolic Risk

NCT01104220
View directory record Official record
Conditions
Non-alcoholic Fatty Liver Disease, Metabolic Syndrome, Metabolically Abnormal Obesity, Metabolically Normal Obesity, Obesity
Interventions
Weight loss
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 90 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Sep 2, 2026, 11:07 AM EDT
Withdrawn Phase 1 Interventional

Wound Healing of Incisional Wounds for Bilateral Hernia Repair

NCT01008111
View directory record Official record
Conditions
Wound Healing
Interventions
Dermabond, Hydrogen Peroxide Oxygen producing gel
Drug
Lead sponsor
Wake Forest University
Other
Eligibility
Up to 5 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Sep 2, 2026, 11:07 AM EDT
Completed Not applicable Interventional Results available

Preoperative Etanercept Before Inguinal Hernia Surgery

NCT00825344
View directory record Official record
Conditions
Inguinal Hernia, Postoperative Pain
Interventions
Etanercept, Saline
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 70 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 4, 2017 · Synced Sep 2, 2026, 11:07 AM EDT
Active, not recruiting Not applicable Interventional Results available

Medtronic Hugo™ Robotic Assisted Surgery (RAS) System in Hernia Surgery (Enable Hernia Repair)

NCT06445504
View directory record Official record
Conditions
Inguinal Hernia, Ventral Hernia
Interventions
Robotic-Assisted Surgery (RAS) Hernia Repair Surgery
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
22 Years and older
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
7
States / cities
Tampa, Florida • Chicago, Illinois • Buffalo, New York + 4 more
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 2, 2026, 11:07 AM EDT
Active, not recruiting Phase 4 Interventional

Methocarbamol in Ventral and Inguinal HR

NCT05388929
View directory record Official record
Conditions
Ventral Hernia, Inguinal Hernia
Interventions
Methocarbamol, Standard Opioid, Standard opioid plus methocarbamol
Drug
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 2, 2026, 11:07 AM EDT
Completed Not applicable Interventional Results available

SurgiMend Mesh at the Hiatus

NCT04282720
View directory record Official record
Conditions
Hiatal Hernia
Interventions
SurgiMend Mesh
Device
Lead sponsor
Kettering Health Network
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Sep 2, 2026, 11:07 AM EDT
Completed Phase 4 Interventional Results available

Strattice in Repair of Inguinal Hernias

NCT00681291
View directory record Official record
Conditions
Hernia, Inguinal
Interventions
Inguinal hernia repair with Ultrapro, Inguinal hernia repair with Strattice
Device
Lead sponsor
LifeCell
Industry
Eligibility
18 Years and older · Male only
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
8
States / cities
New Haven, Connecticut • New Orleans, Louisiana • Baltimore, Maryland + 5 more
Source: ClinicalTrials.gov public record
Updated May 9, 2016 · Synced Sep 2, 2026, 11:07 AM EDT
Recruiting Phase 4 Interventional

Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial

NCT05722002
View directory record Official record
Conditions
Surgery, Pain, Postoperative
Interventions
NSAID, Opioid, Acetaminophen
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
6
States / cities
Ann Arbor, Michigan • Detroit, Michigan • St Louis, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 2, 2026, 11:07 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Difference-In-Differences Analysis of New Persistent Opioid Use After Surgery

NCT04805229
View directory record Official record
Conditions
Opioid Use
Interventions
Retrospective analysis of opioid use after surgery
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
30,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 17, 2021 · Synced Sep 2, 2026, 11:07 AM EDT
Recruiting No phase listed Observational

Robotic Minimally Invasive Inguinal Hernia Repair Post-Market Clinical Study With the DEXTER Robotic System

NCT07181876
View directory record Official record
Conditions
Inguinal Hernia Repair
Interventions
inguinal hernia repair
Device
Lead sponsor
Distalmotion SA
Industry
Eligibility
22 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Buffalo, New York • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 2, 2026, 11:07 AM EDT
Not listed Phase 4 Interventional

Study of Surgical Mesh for Inguinal Hernia Repair

NCT00924755
View directory record Official record
Conditions
Hernia, Inguinal
Interventions
Biomerix Revive™ (surgical mesh for inguinal hernia repair)
Device
Lead sponsor
Biomerix
Industry
Eligibility
19 Years and older · Male only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Omaha, Nebraska • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 3, 2010 · Synced Sep 2, 2026, 11:07 AM EDT