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Showing 1–18 of 18 matching trials from the live ClinicalTrials.gov search.
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Conditions
Respiratory Distress Syndrome, Adult
Interventions
Bronchoscopy, Bronchoalveolar lavage, Endotoxin, Carbon Monoxide
Procedure · Drug
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 40 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Kidney Transplantation
Interventions
Inhaled Carbon Monoxide
Drug
Lead sponsor
Mallinckrodt
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
3
States / cities
San Francisco, California • Chicago, Illinois • Boston, Massachusetts
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of Carbon Monoxide Breathing on Blood Vessel Function

NCT03067701
Conditions
Endothelial Dysfunction
Interventions
Carbon Monoxide
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 39 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Terminated Phase 1 Interventional Accepts healthy volunteers

Hookah Smoking, Carbon Monoxide, and Coronary Endothelial Function

NCT03166787
Conditions
Smoking, Endothelial Dysfunction
Interventions
Charcoal hookah, E-coal hookah, Cigarette, Carbon Monoxide inhalation, Room Air inhalation, vitamin C, tadalafil
Other · Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
21 Years to 49 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Chronic Obstructive Pulmonary Disease, Pulmonary Hypertension
Interventions
iloprost Inhalation, iloprost
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Conditions
Smoking
Interventions
Informing surgical patients about CO monitoring, a brief intervention recommending preoperative abstinence from smoking
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Brain Injury, Chronic
Interventions
Hyperbaric Oxygen, Minimal pressure air
Combination Product
Lead sponsor
Lindell Weaver
Other
Eligibility
18 Years to 70 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
Murray, Utah • Salt Lake City, Utah
Not listed No phase listed Observational Accepts healthy volunteers

Exhaled Carbon Monoxide and Red Blood Cell Turnover

NCT03288233
Conditions
Diabetes Mellitus, Healthy
Interventions
Breath carbon monoxide measurement
Diagnostic Test
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Acute Respiratory Distress Syndrome
Interventions
Inhaled Carbon Monoxide at 200 ppm, Inhaled Medical air
Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
7
States / cities
Boston, Massachusetts • St Louis, Missouri • Brooklyn, New York + 2 more
Conditions
Acute Respiratory Distress Syndrome (ARDS)
Interventions
Inhaled Carbon Monoxide at 100ppm (4 participants), Placebo for Inhaled Carbon Monoxide at 100ppm (2 participants), Inhaled Carbon Monoxide at 200ppm (4 participants), Placebo for Inhaled Carbon Monoxide at 200ppm (2 participants)
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
4
States / cities
Boston, Massachusetts • New York, New York • Durham, North Carolina
Conditions
Hypertension, Pulmonary
Interventions
Carbon Monoxide
Drug
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Smoking, Hookah, Waterpipe Smoking
Interventions
Flavored-Sweetened Waterpipe Tobacco, Unflavored-sweetened waterpipe tobacco, Unflavored-very low sweetened waterpipe tobacco, Flavored-very low sweetened waterpipe
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 50 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Conditions
Carbon Monoxide Poisoning
Interventions
Hyperbaric Oxygen (HBO2) - 3 sessions, Hyperbaric Oxygen (HBO2) - 1 session
Combination Product
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years to 79 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2017
U.S. locations
2
States / cities
Salt Lake City, Utah
Completed Not applicable Interventional Accepts healthy volunteers

Diaphragm Function and Diver Endurance

NCT04679402
Conditions
Respiratory Muscles
Interventions
Carbon monoxide 200 ppm in air
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 45 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Acute Respiratory Distress Syndrome, Sepsis
Interventions
Inhaled Carbon Monoxide at CFK equation-determined personalized dose (200-500 ppm to achieve a COHb level of 6-8%), Inhaled Medical air
Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
6
States / cities
Boston, Massachusetts • St Louis, Missouri • Brooklyn, New York + 2 more
Conditions
Post-Lung Transplantation Bronchiectasis
Interventions
POWERBreathe Plus®, Cardiopulmonary rehabilitation post lung transplant
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
inhaled carbon monoxide, Oxygen
Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
8
States / cities
San Francisco, California • Chicago, Illinois • New Orleans, Louisiana + 4 more
Not listed Phase 1 Interventional Accepts healthy volunteers

Hyperbaric Oxygen, Neutrophil-oxidative Burst, and Cytokines

NCT02563678
Conditions
Infection
Interventions
Hyperbaric Oxygen, Hyperbaric Air/Oxygen, Normobaric oxygen
Drug · Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
2
States / cities
Murray, Utah • Salt Lake City, Utah