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ClinicalTrials.gov public records Last synced Nov 7, 2026, 4:47 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1897–1920 of 2,103 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Injectable saline Clear all

Conditions: Smoking ( Cigarette)
Interventions: Nicotine 0.05 mg/pulse and 0.1 mg/pulse, Saline Placebo (0.5mL injection), sucralose, Sugar syrup (Placebo); Drug · Dietary Supplement
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 59 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Morbid Obesity
Interventions: Not listed
Lead sponsor: William Beaumont Army Medical Center; Federal
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: El Paso, Texas

Conditions: Acute Renal Failure, Acute Kidney Injury
Interventions: I5NP, Placebo; Drug
Lead sponsor: Quark Pharmaceuticals; Industry
Eligibility: 21 Years to 85 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 10
States / cities: Birmingham, Alabama • Phoenix, Arizona • Washington D.C., District of Columbia + 5 more

Conditions: Genital Herpes Simplex Type 2
Interventions: VCL-HB01, VCL-HM01, PBS; Biological
Lead sponsor: Vical; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 165 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 7
States / cities: Birmingham, Alabama • Hollywood, Florida • Indianapolis, Indiana + 4 more

Conditions: Augmentation, Augmentation Revision, General Breast Enlargement, Post-lactational Involution, Asymmetry
Interventions: Mentor Spectra/Becker 80 Breast Implant; Device
Lead sponsor: Mentor Worldwide, LLC; Industry
Eligibility: 22 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2026
U.S. locations: 1
States / cities: Santa Barbara, California

Conditions: Spasticity
Interventions: intramuscular Botox versus oral baclofen; Drug
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Quality of Life, Pelvic Organ Prolapse, Prolapses, Vaginal Vault
Interventions: Dexamethasone, Normal saline; Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Weston, Florida

Conditions: Pain
Interventions: Lidocaine, Normal Saline, Propofol; Drug
Lead sponsor: Children's Hospitals and Clinics of Minnesota; Other
Eligibility: 2 Months to 17 Years
Enrollment: 171 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Saint Paul, Minnesota

Conditions: Inactivated Influenza Vaccine
Interventions: 2005-2006 trivalent inactivated influenza vaccine; Biological
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: 42 Days to 84 Days
Enrollment: 1,375 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Atherosclerotic Cardiovascular Disease
Interventions: Evolocumab, Placebo; Drug · Other
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 259 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: HCG
Interventions: Human Chorionic Gonadotropin, Placebo, Low calorie diet; Drug · Other
Lead sponsor: Dr. Emma's Corporation; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 59 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Colts Neck, New Jersey

Conditions: Lumbar Facet Joint Pain, Low Back Pain
Interventions: Intra-articular injection, Medial branch block, Saline injection; Procedure
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 225 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 2
States / cities: Baltimore, Maryland • Bethesda, Maryland

Conditions: Adenocarcinoma Pancreas
Interventions: PIPAC, Nab-paclitaxel; Device · Drug
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: New Hyde Park, New York

Conditions: Allergic Rhinoconjunctivitis
Interventions: CryJ2-DNA-LAMP plasmid vaccine by intramuscular injection; Biological
Lead sponsor: Immunomic Therapeutics, Inc.; Industry
Eligibility: 18 Years to 63 Years
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 1
States / cities: Honolulu, Hawaii

Conditions: Candidemia, Mycoses, Fungal Infection, Fungemia, Invasive Candidiasis, Pneumocystis, Mold Infection, Invasive Fungal Disease, Prophylaxis of Invasive Fungal Infections, Aspergillus
Interventions: Rezafungin for Injection, Posaconazole, Fluconazole, Trimethoprim-sulfamethoxazole (TMP/SMX), Intravenous Placebo, Oral Placebo; Drug
Lead sponsor: Mundipharma Research Limited; Industry
Eligibility: 18 Years and older
Enrollment: 602 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 18
States / cities: Birmingham, Alabama • Los Angeles, California • Stanford, California + 13 more

Conditions: Postoperative Pain
Interventions: Exparel, Bupivacaine hydrochloride, Patient Controlled Analgesia (PCA); Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Houston, Texas

Conditions: HIV Infections
Interventions: HIV-1 gag DNA, HIV-1 gag DNA plus IL-12 DNA adjuvant, CTL MEP/RC529-SE/GM-CSF (CTL MEP vaccine), Sodium chloride injection (0.9%); Biological
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 144 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Ends 2008
U.S. locations: 3
States / cities: Birmingham, Alabama • Baltimore, Maryland • Nashville, Tennessee

Conditions: Healthy
Interventions: Hyperglycemia, Saline, Exercise, Blood Draws, Fasting procedure; Drug · Other · Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 80 Years · Male only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Urinary Bladder, Overactive, Pelvic Organ Prolapse
Interventions: OnabotulinumtoxinA 100 UNT, Injectable saline; Drug · Other
Lead sponsor: Walter Reed National Military Medical Center; Federal
Eligibility: 18 Years and older · Female only
Enrollment: 138 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Cocaine Use Disorder
Interventions: Exenatide, Placebo; Drug
Lead sponsor: Christopher D. Verrico; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Achondroplasia
Interventions: BMN 111, Normal Saline; Drug
Lead sponsor: BioMarin Pharmaceutical; Industry
Eligibility: 22 Years to 45 Years · Male only
Enrollment: 74 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012
U.S. locations: 1
States / cities: Evansville, Indiana

Conditions: ICU Acquired Weakness
Interventions: FDY-5301, Placebo; Drug · Other
Lead sponsor: Faraday Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 5
States / cities: Torrance, California • Gainesville, Florida • Boston, Massachusetts + 2 more

Conditions: Migraine Headache
Interventions: LY2951742, Placebo; Drug
Lead sponsor: Eli Lilly and Company; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 218 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 37
States / cities: Gilbert, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 30 more

Conditions: Lymphoma, B-Cell
Interventions: Pralatrexate, Vitamin B12, Folic Acid; Drug · Dietary Supplement
Lead sponsor: Spectrum Pharmaceuticals, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 11
States / cities: Beverly Hills, California • Post Falls, Idaho • Chicago, Illinois + 8 more

Search by objective public record fields.

Impact of Sweeteners on the Addictive Threshold of Nicotine

OnQ Pain Pump Effectiveness in Post Operative Pain Control in Bariatric Patients

A Dose Escalation and Safety Study of I5NP to Prevent Acute Kidney Injury (AKI) in Patients at High Risk of AKI Undergoing Major Cardiovascular Surgery (QRK.004)

Safety and Efficacy Trial of DNA Vaccines to Treat Genital Herpes in Adults

Spectra Breast Implant Study

Botox vs. Baclofen for Upper Limb Spasticity

Does Dexamethasone Administration Improve Recovery In Patients Undergoing Minimally Invasive Sacrocolpopexy?

Decreasing Propofol Injection Pain by Pre-Treatment With Lidocaine in Pediatric Procedural Sedation

Safety and Immunogenicity of Inactivated Influenza Virus Vaccine Among Healthy Children 6-12 Weeks of Age

Impact of Evolocumab on the Effects of Clopidogrel in Patients With High On-Treatment Platelet Reactivity

Muscle-Sparing Effect Of Human Chorionic Gonadotropin (hCG) During a Very Low Calorie Diet (VLCD)

Medial Branch Blocks vs. Intra-articular Injections: Randomized, Controlled Study

Pressurized Intraperitoneal Aerosolized Chemotherapy (PIPAC) in Patients With Peritoneal Metastasis From Pancreatic Adenocarcinoma

A Safety and Immunogenicity Phase IB Study of CryJ2-DNA-Lysosomal Associated Membrane Protein (CryJ2 -DNA-LAMP) Plasmid Assessing the Long Term Safety of Previously Treated Subjects

Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation

PAIN - Postoperative Analgesia INvestigation

Study of an HIV Preventive Vaccine Given With or Without an Adjuvant in HIV Uninfected Adults

The Effect of Mixed Exercise and Metabolic Stress in Relationship to Age in Healthy Men

BOTOX® at the Time of Prolapse Surgery for OAB

Exenatide For Reducing the Reinforcing Effects of Cocaine

A Study to Evaluate Safety and Tolerability of BMN 111 Administered to Healthy Adult Volunteers

Evaluation of FDY-5301 in Major Trauma Patients in ICU

A Study of LY2951742 in Participants With Migraine

Study of Pralatrexate to Treat Participants With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma