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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:31 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 395 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Injection of botulinum toxin A Clear all

Conditions: Glabellar Frown Lines
Interventions: OnabotulinumtoxinA; Drug
Lead sponsor: Clinical Testing of Beverly Hills; Other
Eligibility: 18 Years and older · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 2
States / cities: Encino, California • Newport Beach, California

Conditions: Pain
Interventions: Botulinum Toxin A, Placebo - Saline; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2013
U.S. locations: 1
States / cities: Stanford, California

Conditions: Forehead Lines
Interventions: OnabotulinumtoxinA X, Placebo; Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years and older
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 8
States / cities: Newport Beach, California • Mount Kisco, New York • Rochester, New York + 4 more

Conditions: Overactive Bladder Syndrome
Interventions: Repris Needle; Device
Lead sponsor: Uro-1 Medical; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Cartersville, Georgia

Conditions: Spasmodic Dysphonia
Interventions: Lidocaine, Vibrating wand; Drug · Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Primary Focal Hyperhidrosis of the Hands
Interventions: BTX-A; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 16 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Overactive Bladder
Interventions: Intradetrusor Botox Injections; Biological
Lead sponsor: The Methodist Hospital Research Institute; Other
Eligibility: 18 Years and older · Female only
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Cervical Dystonia
Interventions: botulinum toxin type A, botulinum toxin type A Formulation 2, Normal Saline; Biological · Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 242 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Cold Intolerance
Interventions: Botulinum toxin type A; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 75 Years
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Glabellar Lines
Interventions: OnabotulinumtoxinA X, Placebo; Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years and older
Enrollment: 328 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 18
States / cities: Glendale, Arizona • Los Angeles, California • Newport Beach, California + 15 more

Conditions: Glabellar Frown Lines
Interventions: AbobotulinumtoxinA, Placebo; Biological · Other
Lead sponsor: Galderma R&D; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 301 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 11
States / cities: Redondo Beach, California • San Diego, California • Westport, Connecticut + 8 more

Conditions: Cerebral Palsy, Spasticity
Interventions: IncobotulinumtoxinA (8 Units per kg body weight), IncobotulinumtoxinA (6 Units per kg body weight), IncobotulinumtoxinA (2 Units per kg body weight); Drug
Lead sponsor: Merz Pharmaceuticals GmbH; Industry
Eligibility: 2 Years to 17 Years
Enrollment: 351 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 6
States / cities: Gulf Breeze, Florida • Loxahatchee Groves, Florida • Savannah, Georgia + 3 more

Conditions: Overactive Bladder
Interventions: onaBoNT-A, Oxybutynin ER; Drug
Lead sponsor: Christopher Patrick Smith; Other
Eligibility: 18 Years to 80 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 2
States / cities: Houston, Texas

Conditions: Obstructed Defecation Syndrome (ODS)
Interventions: Botulinum Toxin-A, Normal Saline; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 90 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cervicobrachial Neuralgia, Myofascial Pain Syndromes
Interventions: Botulinum toxin serotype A; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 65 Years
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2003
U.S. locations: 1
States / cities: Santa Monica, California

Conditions: Cleft Lip, Scarring, Cleft Palate
Interventions: Botulinum Toxin Type A, Normal Saline Injection; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: Up to 6 Months
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Cerebral Palsy
Interventions: Not listed
Lead sponsor: Holland Bloorview Kids Rehabilitation Hospital; Other
Eligibility: 2 Years to 18 Years
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2022
U.S. locations: 9
States / cities: Sacramento, California • Aurora, Colorado • Wilmington, Delaware + 5 more

Conditions: Ventral Hernia, Abdominal Hernia
Interventions: BOTOX Dose A, Placebo for BOTOX, BOTOX Dose B, BOTOX Dose C; Drug
Lead sponsor: AbbVie; Industry
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 2
States / cities: Mineola, New York • Charlotte, North Carolina

Conditions: Pain
Interventions: botulinum type a; Drug
Lead sponsor: Henry Ford Health System; Other
Eligibility: 25 Years to 55 Years · Female only
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Wrinkles
Interventions: onabotulinumtoxinA, JUVÉDERM; Drug
Lead sponsor: AboutSkin Dermatology and DermSurgery, PC; Industry
Eligibility: 25 Years to 65 Years
Enrollment: 156 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Englewood, Colorado

Conditions: Equinus Contracture
Interventions: Botulinum toxin type A, sodium chloride; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Urinary Bladder, Overactive, Incontinence, Urge, Incontinence, Urinary, Urinary Urge Incontinence, Urinary Frequency More Than Once at Night, Nocturia
Interventions: OnabotulinumtoxinA 100 UNT; Drug
Lead sponsor: University of South Florida; Other
Eligibility: 18 Years and older · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • Tampa, Florida

Conditions: Glabellar Lines
Interventions: AGN-151586, BOTOX; Drug
Lead sponsor: AbbVie; Industry
Eligibility: 18 Years and older
Enrollment: 143 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 8
States / cities: Glendale, Arizona • Newport Beach, California • Vista, California + 5 more

Conditions: Muscle Strength, Botulinum Toxins, Type A
Interventions: Botulinum Toxin, Type A, Saline; Drug
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years to 54 Years
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2015
U.S. locations: 2
States / cities: Loma Linda, California

Search by objective public record fields.

Duration of Botox Using OLD Versus COLD for Treatment of Glabellar Lines

Subcutaneous Botulinum Toxin for Cutaneous Allodynia

A Study To Assess the Adverse Effects and Change in Condition of OnabotulinumtoxinA X Injection in Adult Participants With Forehead Lines

Use of Repris Needle in Bladder Injection

Spasmodic Dysphonia Pain

BTX-A Treatment for Palmar Hyperhidrosis

Procedural Discomfort Related to Number of Intradetrusor Botox Injections

Study to Evaluate Safety, Efficacy of Botulinum Toxin Type A in Patients With Cervical Dystonia

Botulinum Toxin Type A for Cold Intolerance Secondary to Digital Amputations and Replantations: A Pilot Study

A Study to the Assess the Change in Condition and Adverse Events of OnabotulinumtoxinA X Injection in Adult Participants With Glabellar Lines

Efficacy and Safety of a New Dilution and Injection Volume of AbobotulinumtoxinA for the Treatment of Glabellar Lines

Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Arm(s) or of Arm(s) and Leg(s) in Cerebral Palsy

OnabotulinumtoxinA (onaBoNT-A) Versus Oral Oxybutynin ER

Effects of Botox in Obstructed Defecation Syndrome

Study to Evaluate the Efficacy of Botulinum Toxin Serotype A Injections for Cervicobrachial Myofascial Syndrome

Botulinum Toxin to Improve Cosmesis of Primary Cleft Lip Repair

Cerebral Palsy Hip Outcomes Project - International Multi-centre Study

A Study to Evaluate Adverse Events and Effectiveness of OnabotulinumtoxinA in Participants Undergoing Open Abdominal Ventral Hernia Repair for the Achievement of Primary Fascial Closure Without the Use of Component Separation Technique

Novel Technique for Botulinum Toxin Injection to Minimize Patient Discomfort

Study of BOTOX and JUVEDERM for Treatment of Moderate to Severe Facial Wrinkles and Folds

The Effect of Botulinum Toxin A Injections on Ankle Dorsiflexion Following Internal Fixation of Tibial Pilon Fractures

Post-procedural Pain Associated With 5 Versus 20 Intravesical Injections of Onabotulinumtoxin A

A Study to Evaluate Sequential Administration of Injections of AGN-151586 Followed by BOTOX in Adult Participants for Treatment of Glabellar Lines

Assessment of the Effect of Botulinum Toxin in Extensor Digitorum Brevis Via Strain Gauge and Nerve Conduction Studies