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ClinicalTrials.gov public records Last synced Oct 2, 2026, 4:57 PM EDT

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Showing 49–72 of 80 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Inspiratory muscle strength training Clear all
Completed Not applicable Interventional

High Dose Inspiratory Muscle Training in LOPD

NCT05431127
View directory record Official record
Conditions
Late-Onset Pompe Disease, Lysosomal Disease
Interventions
IMT therapy using the Pr02 mobile device
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Oct 2, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Respiratory Muscle Function in Heart Failure

NCT03924479
View directory record Official record
Conditions
Heart Failure, Diastolic
Interventions
PowerBreathe (Breathing muscle training)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 22, 2024 · Synced Oct 2, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

Smart Telehealth Exercise Intervention to Reduce COPD Readmissions

NCT03089853
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Neuromuscular electrical stimulation (NMES)
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
40 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 22, 2022 · Synced Oct 2, 2026, 4:57 PM EDT
Completed Phase 1 Interventional

Inspiratory Muscle Training in Ventilator Dependent Patients

NCT00419458
View directory record Official record
Conditions
Failure to Wean, Respiratory Failure, Ventilator Dependent
Interventions
inspiratory muscle strength training
Procedure
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
16 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 9, 2009 · Synced Oct 2, 2026, 4:57 PM EDT
Completed Phase 4 Interventional Results available

Maintain Respiratory Muscle Function and Reduce Pneumonia Risk in Cancer Patients

NCT03469271
View directory record Official record
Conditions
Cancer
Interventions
1,25 (OH)2 D3, Inspiratory isometric resistance training, Oral Placebo, Sham Inspiratory Isometric Resistance Training, Threshold Inspiratory Muscle Trainer (IMT)
Drug · Other · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 26, 2023 · Synced Oct 2, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

Respiratory Muscle Strength Training in Presbyphonia

NCT03557775
View directory record Official record
Conditions
Presbylarynx
Interventions
Inspiratory Muscle Strength Training (IMST), Expiratory Muscle Strength Training (EMST), Voice Exercises
Device · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
50 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 7, 2020 · Synced Oct 2, 2026, 4:57 PM EDT
Not listed Not applicable Interventional

The Prescriptive Validity of a Novel Fall Risk Clinical Prediction Rule for People With COPD

NCT05173532
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Balance Training, Breathing and Stretching Exercises
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
60 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
4
States / cities
Houston, Texas • Sugar Land, Texas • Webster, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Oct 2, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

Fibromyalgia Integrative Training for Adolescents With Juvenile Fibromyalgia

NCT03268421
View directory record Official record
Conditions
Fibromyalgia, Myofascial Pain Syndrome, Muscular Diseases, Musculoskeletal Disease, Rheumatic Diseases
Interventions
Fibromyalgia Integrative Training for Teens, Cognitive Behavioral Therapy, Graded Aerobic Exercise
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Years to 18 Years
Enrollment
389 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
6
States / cities
Hartford, Connecticut • Indianapolis, Indiana • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2025 · Synced Oct 2, 2026, 4:57 PM EDT
Recruiting Not applicable Interventional

Pre-operative Inspiratory Muscle Strength Training in Total Joint Surgery

NCT05381818
View directory record Official record
Conditions
Arthropathy of Knee, Arthropathy of Hip, Lower Extremity Fracture, Orthopedic Disorder
Interventions
Daily Inspiratory Muscle Training (dIMT), Acute Inspiratory Muscle Training (aIMT), Standard of Care (SOC)
Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 100 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 2, 2026, 4:57 PM EDT
Recruiting Not applicable Interventional

Respiratory Strength Training in Heart Transplant Recipients

NCT06190171
View directory record Official record
Conditions
Dysphagia, Heart Transplant Recipients
Interventions
Active respiratory muscle strength training, Sham respiratory muscle strength training
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 2, 2026, 4:57 PM EDT
Completed Not applicable Interventional

Home-Based Respiratory Muscle Strength Training Program for Individuals With Post-COVID-19 Persistent Dyspnea

NCT06091280
View directory record Official record
Conditions
Post-COVID-19 Syndrome, Dyspnea
Interventions
Respiratory Muscle Strength Trainers
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Oct 2, 2026, 4:57 PM EDT
Not listed Not applicable Interventional

Weathering the Storm: Lung, Heart, and Brain Vascular Rehabilitation for COVID-19

NCT04887272
View directory record Official record
Conditions
Covid19
Interventions
Supervised Exercise Training Protocol, Inspiratory Muscle and Exercise Training
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 14, 2021 · Synced Oct 2, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Health in Individuals With a Spinal Cord Injury: a Prospective Study

NCT03743077
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Exercise training including inspiratory muscle training
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 27, 2021 · Synced Oct 2, 2026, 4:57 PM EDT
Completed Not applicable Interventional

Enhancing Resilience in Young Stroke Survivors With Res-ET

NCT05348044
View directory record Official record
Conditions
Resilience, Stroke
Interventions
Res-ET intervention
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 55 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 2, 2026, 4:57 PM EDT
Recruiting Not applicable Interventional

Home Based Functional Balance Intervention for Multiple Sclerosis

NCT07355387
View directory record Official record
Conditions
Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis (MS) Primary Progressive, Multiple Sclerosis (MS) Secondary Progressive, Multiple Sclerosis Acute and Progressive
Interventions
Multicomponent balance intervention consisting of four components including dual-tasking, functional strength, vestibular and dynamic balance., Stretching
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
40 Years to 90 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 2, 2026, 4:57 PM EDT
Not listed Not applicable Interventional

Telehealth and Onsite Maintenance Exercise in Chronic Lung Disease

NCT06304207
View directory record Official record
Conditions
Copd, COPD Exacerbation, COPD Bronchitis, Emphysema or COPD, Chronic Lung Disease, Pulmonary Fibrosis, Interstitial Lung Disease, Bronchiectasis, Chronic Asthma, Chronic Asthmatic Bronchitis
Interventions
Onsite Maintenance Exercise Training, Telehealth Maintenance Exercise
Combination Product
Lead sponsor
MGH Institute of Health Professions
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 1, 2024 · Synced Oct 2, 2026, 4:57 PM EDT
Recruiting Not applicable Interventional

Respiratory Muscle Training to Improve Cerebrovascular and Immune Function

NCT07406295
View directory record Official record
Conditions
Obesity, Cerebrovascular Function, Immune Cells Activity
Interventions
High intensity inspiratory muscle strength training, Low intensity
Device
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 45 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 2, 2026, 4:57 PM EDT
Completed Not applicable Interventional

Airway Muscle Training for Obstructive Sleep Apnea

NCT02259660
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Respiratory muscle strength training, Sham respiratory muscle strength training
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 11, 2018 · Synced Oct 2, 2026, 4:57 PM EDT
Completed Phase 2 Interventional Results available

Nitrite Supplementation in Long COVID Patients

NCT05618574
View directory record Official record
Conditions
Long COVID, Cardiorespiratory Fitness
Interventions
140 ml per day of Beet-It nitrate beverage (James White Drinks Ltd., Ipswich, UK), 210 ml of nitrate-depleted placebo
Dietary Supplement
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 2, 2026, 4:57 PM EDT
Recruiting Not applicable Interventional

Effects of High-Resistance Inspiratory Muscle Strength Training on Cardiorenal and Vascular Function in Youth and Young Adults With Type 2 Diabetes

NCT06936670
View directory record Official record
Conditions
Diabetes Mellitus Type 2
Interventions
Inspiratory Muscle Strength Training (IMST), Sham Training
Device
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
14 Years to 40 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 13, 2025 · Synced Oct 2, 2026, 4:57 PM EDT
Completed Phase 2 Interventional Results available

Masked Faces in Parkinson Disease: Mechanism and Treatment

NCT00350402
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Respiratory muscle strength training
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
45 Years to 80 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 6, 2012 · Synced Oct 2, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Covid-19 Virtual Recovery Study

NCT04950725
View directory record Official record
Conditions
Covid19
Interventions
Strength RMT, Strength RMT and nasal breathing, Endurance RMT, Endurance RMT and nasal breathing, Low dose RMT
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
2,268 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 2, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

Respiratory Strength Training in Cardiac Surgical Patients

NCT04887415
View directory record Official record
Conditions
Cardiovascular Diseases, Thoracic Diseases, Surgery, Surgery--Complications, Dysphagia
Interventions
Respiratory Strength Training (RST) Program
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Oct 2, 2026, 4:57 PM EDT
Completed Not applicable Interventional

Support for People Undergoing Chemotherapy

NCT00740038
View directory record Official record
Conditions
Quality of Life, Cancer
Interventions
Stress Management training, Exercise Training, Usual care, Combined stress management and exercise training
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
471 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Oct 2, 2026, 4:57 PM EDT