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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Intensive OutPatient Therapy Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Preventing Vulnerable Child Syndrome in the NICU With Cognitive Behavioral Therapy (PreVNT Trial)

NCT03906435
View directory record Official record
Conditions
Premature Infant, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Development, Child, Parent-Child Relations
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 18, 2026, 12:34 AM EDT
Terminated Not applicable Interventional

Telemonitoring Device in Managing Outpatient Care of Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia After Intensive Chemotherapy

NCT02226497
View directory record Official record
Conditions
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Interventions
Health Telemonitoring, Quality-of-Life Assessment, Questionnaire Administration, Supportive Care
Device · Other · Procedure
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 9, 2020 · Synced Sep 18, 2026, 12:34 AM EDT
Not yet recruiting Not applicable Interventional

Expanding Access to mTBI Treatment for Veterans and Service Members With Co-occurring Substance Use

NCT06620900
View directory record Official record
Conditions
Concussion, Mild Traumatic Brain Injury, Brain Injury, Traumatic Brain Injury, Substance Use, Substance Use Disorder (SUD)
Interventions
Integrated Model of Care
Other
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 30, 2024 · Synced Sep 18, 2026, 12:34 AM EDT
Completed Not applicable Interventional Results available

Effectiveness of Extended Treatments for Drug Dependence

NCT00685659
View directory record Official record
Conditions
Cocaine Dependence
Interventions
Intensive Outpatient Treatment, Adaptive telephone-based counseling, Adaptive telephone-based counseling plus incentives
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
332 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 6, 2017 · Synced Sep 18, 2026, 12:34 AM EDT
Completed Not applicable Interventional Results available

A Randomized Trial of Outpatient Oxygen Weaning Strategies in Premature Infants

NCT01994954
View directory record Official record
Conditions
Premature Infants
Interventions
RHO
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
Up to 37 Weeks
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
8
States / cities
Farmington, Connecticut • Lexington, Kentucky • Boston, Massachusetts + 5 more
Source: ClinicalTrials.gov public record
Updated May 29, 2023 · Synced Sep 18, 2026, 12:34 AM EDT
Completed Phase 1Phase 2 Interventional

Colorado Women's TC Project

NCT00249561
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Recovery by Choice, The Intensive Outpatient Program (IOP)
Behavioral
Lead sponsor
National Development and Research Institutes, Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
610 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 19, 2011 · Synced Sep 18, 2026, 12:34 AM EDT
Completed Not applicable Interventional

Project Remission: Maximizing Outcomes With Intensive Treatments for Combat-Related PTSD

NCT03529435
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Massed Prolonged Exposure, Intensive Outpatient Prolonged Exposure
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 65 Years
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
4
States / cities
Fort Hood, Texas • San Antonio, Texas • Waco, Texas
Source: ClinicalTrials.gov public record
Updated Aug 7, 2022 · Synced Sep 18, 2026, 12:34 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Study of Mental Health and Relationships

NCT06534827
View directory record Official record
Conditions
Mental Health
Interventions
Great Life Mentoring
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
9 Years to 16 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Sep 18, 2026, 12:34 AM EDT
Completed Phase 2 Interventional

Intermittent Hypoxia and Caffeine in Infants Born Preterm

NCT03321734
View directory record Official record
Conditions
Intermittent Hypoxia
Interventions
Caffeine, Placebos
Drug
Lead sponsor
Children's National Research Institute
Other
Eligibility
32 Weeks to 36 Weeks
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
15
States / cities
Loma Linda, California • Washington D.C., District of Columbia • Orlando, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced Sep 18, 2026, 12:34 AM EDT
Recruiting Not applicable Interventional

Project COMET: Massed Prolonged Exposure for PTSD and SUD

NCT06968832
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Substance Use Disorders (SUD), Comorbidity, Trauma and Stressor Related Disorders
Interventions
Massed Prolonged Exposure Therapy (M-PE), Standard outpatient SUD care
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Sep 18, 2026, 12:34 AM EDT
Completed Not applicable Interventional

The Brave Initiative: Bringing Rehabilitation to American Veterans in an Enriched Environment

NCT02339220
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Constraint-Induced Movement Therapy (CIMT), Lakeshore Enriched Fitness Training (LEFT), standard Transfer Package (sTP), enhanced Transfer Package (eTP)
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 90 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 5, 2023 · Synced Sep 18, 2026, 12:34 AM EDT
Completed Not applicable Interventional

Evaluating Supplementing Residential Substance Use Treatment With Written Exposure Therapy for Veterans With Post Traumatic Stress Disorder (PTSD) and Substance Use Disorders (SUD)

NCT05536908
View directory record Official record
Conditions
PTSD, Substance Use Disorders
Interventions
Residential Written Exposure Therapy, Treatment as Usual
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Salem, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Sep 18, 2026, 12:34 AM EDT
Completed Not applicable Interventional

Ready for Change: Enhancing Motivational Engagement Prior to IIPT

NCT04093921
View directory record Official record
Conditions
Chronic Pain
Interventions
MET-based therapy, Standard Care
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
8 Years to 18 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Sep 18, 2026, 12:34 AM EDT
Completed Not applicable Interventional

Clinical Monitoring to Facilitate Continuous Care for Substance Abusing Clients

NCT01831999
View directory record Official record
Conditions
Substance-Related Disorders, Mental Disorders
Interventions
RecoveryTrack - Extended Care (RT-E)
Behavioral
Lead sponsor
Treatment Research Institute
Other
Eligibility
18 Years and older
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
4
States / cities
Collingswood, New Jersey • Marlton, New Jersey • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 27, 2023 · Synced Sep 18, 2026, 12:34 AM EDT
Completed Not applicable Interventional

Cognitive Behavioral Therapy for Insomnia in Substance Use Disorders

NCT03208855
View directory record Official record
Conditions
Substance Use Disorders, Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Male only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 31, 2022 · Synced Sep 18, 2026, 12:34 AM EDT
Completed Not applicable Interventional

Integrated Supportive and Palliative Care for Older Adults in the ICU

NCT04921631
View directory record Official record
Conditions
Critical Illness
Interventions
Early Integration of Specialty Palliative Care with Critical Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years and older
Enrollment
1,091 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 18, 2026, 12:34 AM EDT
Completed Phase 3 Interventional

Cognitive Behavioral Therapy (CBT) for Posttraumatic Stress Disorder (PTSD) in Community Addiction Treatment

NCT01457391
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Substance-Related Disorders
Interventions
Cognitive Behavioral Therapy, Individual Addiction Counseling, Treatment-as-usual
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
443 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
4
States / cities
Berlin Corners, Vermont • Brattleboro, Vermont • Burlington, Vermont + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 15, 2015 · Synced Sep 18, 2026, 12:34 AM EDT
Completed Not applicable Interventional

Buprenorphine and Substance Abuse Services for Prescription Opioid Dependence

NCT02496403
View directory record Official record
Conditions
Opiate Substitution Treatment
Interventions
Standard Medical Management (SMM)
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
239 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 25, 2019 · Synced Sep 18, 2026, 12:34 AM EDT
Not listed Not applicable Interventional

Preventing OUD in Justice-Involved Youth

NCT04901312
View directory record Official record
Conditions
Substance Use Disorders, Recidivism
Interventions
Adolescent Community Reinforcement Approach, Assertive Continuing Care, Trauma Affect Regulation Guide for Education and Therapy, Motivational Interviewing, Opioid Education Workbook
Behavioral · Other
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
15 Years to 25 Years
Enrollment
215 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Olympia, Washington
Source: ClinicalTrials.gov public record
Updated Oct 26, 2022 · Synced Sep 18, 2026, 12:34 AM EDT
Completed Phase 2 Interventional

Effectiveness of Enhanced Treatments for Drug Dependence

NCT01153477
View directory record Official record
Conditions
Cocaine Dependence
Interventions
Telephone Monitoring and Counseling - Enhanced
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 29, 2017 · Synced Sep 18, 2026, 12:34 AM EDT
Completed Not applicable Interventional

Predicting Treatment Outcomes With Intensive Outpatient Treatment for PTSD

NCT04307498
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Intensive Outpatient Program - Prolonged Exposure
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 21, 2022 · Synced Sep 18, 2026, 12:34 AM EDT
Completed Phase 2 Interventional

Targeting HIV Risk Behaviors in Juvenile Drug Court-Involved Youth

NCT01511380
View directory record Official record
Conditions
Substance Use, Sexual Risk Behaviors
Interventions
Risk Reduction Therapy for Adolescents, Usual services
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years to 17 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 3, 2016 · Synced Sep 18, 2026, 12:34 AM EDT
Completed Not applicable Interventional Results available

Behavioral Treatment of Adolescent Substance Use

NCT02063984
View directory record Official record
Conditions
Substance Use Disorders
Interventions
Intensive Outpatient Treatment (IOP) + Contingency Management (CM), Working Memory Training
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
12 Years to 26 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 3, 2021 · Synced Sep 18, 2026, 12:34 AM EDT
Completed Not applicable Interventional Results available

TMS for Veterans Attending a 2-week Intensive Outpatient Program for PTSD

NCT06271733
View directory record Official record
Conditions
PTSD
Interventions
TMS
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 18, 2026, 12:34 AM EDT