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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:53 AM EST

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Showing 1–24 of 114 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Intensive lifestyle Intervention Clear all

Conditions: Overweight, Pregnancy
Interventions: Intensive Lifestyle Intervention (ILI), Usual Care; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 210 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: New York, New York

Conditions: Obesity, Diabetes Mellitus, Type 2, PreDiabetes
Interventions: Intensive Lifestyle Intervention; Behavioral
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 40 Years to 70 Years
Enrollment: 352 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Infertility, Female
Interventions: Caloric Restriction, Orlistat, Moderate physical activity; Other · Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 379 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 10
States / cities: San Francisco, California • Augusta, Georgia • Southfield, Michigan + 7 more

Conditions: Diabetes Mellitus, Diabetes Mellitus, Type 2, PreDiabetes, Hypertension, High Blood Pressure, High Blood Sugar, Obesity, Overweight, Overweight and Obesity, Overweight or Obesity
Interventions: The Diabetes Prevention Program; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 25 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Weight Loss, Diabetes Mellitus, Type 2, Psychotic Disorders
Interventions: Premier Lifestyle Intervention with DASH Diet; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 3
States / cities: Portland, Oregon

Conditions: Obesity
Interventions: Calorie-counting, MyPlate; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 261 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 2
States / cities: Long Beach, California • Los Angeles, California

Conditions: Obesity, Childhood
Interventions: COACH: Healthy Bodies, COACH: Strong Minds; Behavioral
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 3 Years to 5 Years
Enrollment: 117 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Cancer, Survivorship
Interventions: RISE (Reinvent, Integrate, Strengthen, Expand) Intervention; Other
Lead sponsor: Arash Asher, MD; Other
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Opioid Use Disorder
Interventions: Managing Physical Reactions to Overwhelming Emotions (IMPROVE), Health Education Training (HET); Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Cardiovascular Disease
Interventions: Lifestyle behavior change program, Pamphlets; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 40 Years to 64 Years · Female only
Enrollment: 258 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2005
U.S. locations: 1
States / cities: Wilmington, North Carolina

Conditions: Obesity
Interventions: Evaluate Healthy Lifestyle Program on cognitive outcomes; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 65 Years and older
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Obesity, Pre-diabetes, Metabolic Syndrome
Interventions: Self-management program (SM), Care management program (CM); Behavioral
Lead sponsor: Palo Alto Medical Foundation; Other
Eligibility: 18 Years and older
Enrollment: 241 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Weight Loss, Weight Gain, Obesity
Interventions: Intensive lifestyle change therapy, Tirzepatide; Behavioral · Drug
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 18 Years and older
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Type 2 Diabetes
Interventions: Intensive education and lifestyle support, Standard of Care control group; Behavioral
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 211 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Obesity
Interventions: Teaching Kitchen Collaborative Curriculum; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 30 Years to 65 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Hypertensive Disorder of Pregnancy
Interventions: Nifedipine ER; Drug
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Cardiovascular Diseases, Heart Diseases, Coronary Disease, Diabetes Mellitus, Atherosclerosis, Cerebral Arteriosclerosis, Hypertension
Interventions: Lifestyle Changes, Antiplatelet Agents, Beta Blocker, ACE Inhibitors; Behavioral · Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 21 Years to 80 Years
Enrollment: 525 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Obesity, Metabolic Disease
Interventions: Standard Care, Culturally-tailored dietary and behavioral intensive lifestyle intervention, Placebo, Tirzepatide; Behavioral · Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 21 Years to 65 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Santa Barbara, California

Conditions: Hypertension, Blood Pressure
Interventions: Multicomponent Intervention, Enhanced Usual Care; Behavioral
Lead sponsor: Tulane University; Other
Eligibility: 40 Years and older
Enrollment: 1,272 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 2
States / cities: New Orleans, Louisiana • Biloxi, Mississippi

Conditions: Overweight
Interventions: Lifestyle modification; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 11 Years to 18 Years · Female only
Enrollment: 257 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2013
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Class I Obesity, Pediatric Obesity
Interventions: Virtual Housecalls; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 12 Years to 15 Years
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Henrico, Virginia

Conditions: PreDiabetes
Interventions: Online diabetes prevention program, Standard Care; Behavioral
Lead sponsor: Omada Health, Inc.; Industry
Eligibility: 19 Years and older
Enrollment: 598 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Overweight and Obesity
Interventions: Experimental: Web-based only (WO) weight intervention, Experimental: WO plus peer-led discussion board (WD), Experimental: WO & professional email counseling (WE); Behavioral
Lead sponsor: University of Nebraska; Other
Eligibility: 40 Years to 69 Years · Female only
Enrollment: 301 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Sexual Violence
Interventions: Green Dot, Wellness Initiatives for Student Empowerment; Behavioral
Lead sponsor: University of Kentucky; Other
Eligibility: 18 Years to 24 Years
Enrollment: 427 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Lexington, Kentucky

Search by objective public record fields.

LIFT: Lifestyle Interventions For Two

Promoting Successful Weight Loss in Primary Care in Louisiana Using Information Technology

Improving Reproductive Fitness Through Pretreatment With Lifestyle Modification in Obese Women With Unexplained Infertility

A Virtual Cardiometabolic Health Program for African Immigrants: The Afro-DPP Program

Reducing Weight and Diabetes Risk in an Underserved Population (STRIDE)

Is MyPlate Approach to Helping Overweight Patients Lose Weight More Patient-centered?

Competency-based Approaches to Community Health

RISE (Reinvent, Integrate, Strengthen, Expand) Self-Management Program for Cancer Survivors: A Feasibility Study

Brief Digitally-Enhanced Intervention for Reducing Alcohol Use During MOUD

NC Enhanced WISEWOMAN Project

Evaluation of the Healthy Lifestyle Program on Cognitive Outcomes

Evaluation of Lifestyle Interventions to Treat Elevated Cardiometabolic Risk in Primary Care

Role Of Metabolic Adaptation In Weight Regain

Lifestyle Improvement Through Food and Exercise (LIFE)Study

A Culinary-Based Intensive Lifestyle Program for Patients With Obesity

Intensive Postpartum Antihypertensive Treatment

Reducing Total Cardiovascular Risk in an Urban Community

Effects of Tirzepatide Plus Intensive Lifestyle Therapy on Body Weight and Metabolic Health in Latinos With Obesity

Implementation of Multifaceted Patient-Centered Treatment Strategies for Intensive Blood Pressure Control (IMPACTS)

Barriers to Effective Weight Loss in Overweight Adolescents

Virtual Housecalls: Redesigning Pediatric Primary Care Adolescent Obesity Treatment

Preventing Diabetes With Digital Health and Coaching

Web-Based Weight Loss & Weight Maintenance Intervention for Older Rural Women, Also Known as Women Weigh-in for Wellness

A Pilot of Bystander Training Programming in Sexual Violence and Subtance Abuse