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ClinicalTrials.gov public records Last synced Oct 26, 2026, 2:14 PM EDT

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Showing 697–720 of 975 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Intensive therapy Clear all
Completed Phase 1 Interventional

Cardiac Safety Study of Brentuximab Vedotin (SGN-35)

NCT01026233
View directory record Official record
Conditions
Disease, Hodgkin, Lymphoma, Large-Cell, Anaplastic, Lymphoma, Non-Hodgkin
Interventions
brentuximab vedotin
Drug
Lead sponsor
Seagen Inc.
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
8
States / cities
Birmingham, Alabama • Duarte, California • Stanford, California + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 12, 2014 · Synced Oct 26, 2026, 2:14 PM EDT
Completed Phase 3 Interventional

Pediatric Intensive Care Units (ICUs) at Emory-Children's Center Glycemic Control: The PedETrol Trial

NCT01116752
View directory record Official record
Conditions
Pediatric Patient (1m-21y), ICU Admission, Hyperglycemia
Interventions
Active Glycemic Control Strict (80-140mg/dL) vs. Conservative (190-220mg/dL) (with or without Continuous Glucose Monitoring)
Other
Lead sponsor
Indiana University
Other
Eligibility
1 Month to 18 Years
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 31, 2015 · Synced Oct 26, 2026, 2:14 PM EDT
Completed Not applicable Interventional

Video Game-based Therapy for Arm Weakness In Progressive Multiple Sclerosis

NCT03094364
View directory record Official record
Conditions
Primary Progressive Multiple Sclerosis, Hemiparesis
Interventions
Gaming CI Therapy
Behavioral
Lead sponsor
University of Massachusetts, Lowell
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Oct 26, 2026, 2:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigating Fitness Interventions in the Elderly (INFINITE)

NCT01048736
View directory record Official record
Conditions
Obesity, Older Adults, Sedentary
Interventions
Exercise Only, Exercise + Diet
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years to 80 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 26, 2026, 2:14 PM EDT
Not listed Phase 3 Interventional

Methylnaltrexone for Treatment of Opiate-Induced Constipation in the Intensive Care Unit

NCT01050595
View directory record Official record
Conditions
Opioid-induced Constipation
Interventions
Methylnaltrexone Bromide, Placebo-Normal Saline
Drug
Lead sponsor
St. John Health System, Michigan
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Southfield, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 15, 2010 · Synced Oct 26, 2026, 2:14 PM EDT
Completed Phase 3 Interventional Results available

A Study of the Effectiveness of Venetoclax in Combination With Azacitidine or Decitabine in an Outpatient Setting in Patients With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy

NCT03941964
View directory record Official record
Conditions
Acute Myeloid Leukemia (AML), Cancer
Interventions
Venetoclax, Azacitidine, Decitabine
Drug
Lead sponsor
AbbVie
Industry
Eligibility
12 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
16
States / cities
Tempe, Arizona • Denver, Colorado • Lone Tree, Colorado + 12 more
Source: ClinicalTrials.gov public record
Updated Mar 20, 2023 · Synced Oct 26, 2026, 2:14 PM EDT
Completed Phase 2 Interventional Results available

A Study of FMT in Patients With AML Allo HSCT in Recipients

NCT03678493
View directory record Official record
Conditions
Acute Myeloid Leukemia, Allogeneic Hematopoietic Cell Transplantation
Interventions
Fecal Microbiota Transplant (FMT), Placebo
Biological · Other
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Oct 26, 2026, 2:14 PM EDT
Active, not recruiting Phase 1 Interventional

A Study of Revumenib in Combination With Intensive Chemotherapy in Participants With Acute Myeloid Leukemias

NCT06226571
View directory record Official record
Conditions
Acute Myeloid Leukemias
Interventions
Revumenib, Chemotherapy Regimen, HiDAC
Drug
Lead sponsor
Syndax Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
28
States / cities
Goodyear, Arizona • Burbank, California • Duarte, California + 23 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 26, 2026, 2:14 PM EDT
Completed Phase 2 Interventional

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Central Nervous System Lymphoma

NCT00003632
View directory record Official record
Conditions
Lymphoma
Interventions
filgrastim, carmustine, cytarabine, etoposide, melphalan, methotrexate, peripheral blood stem cell transplantation
Biological · Drug · Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1998
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 16, 2013 · Synced Oct 26, 2026, 2:14 PM EDT
Terminated Phase 1 Interventional

Effect of Music Therapy on Families of Burn Patients

NCT00824681
View directory record Official record
Conditions
Burns
Interventions
Sound Of Family Together (S.O.F.T.) Music Program, Non-Therapy Related Activities (NTRA)
Behavioral · Other
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
6 Years to 14 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 23, 2010 · Synced Oct 26, 2026, 2:14 PM EDT
Terminated Not applicable Interventional

Standard Care Coordination Expansion Pilot

NCT04415515
View directory record Official record
Conditions
Superutilizers, Health Care Utilization
Interventions
RN case management, Community Health Worker Case Management, RN Standard care coordination and disease management
Behavioral
Lead sponsor
UnitedHealthcare
Other
Eligibility
18 Years and older
Enrollment
592,023 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
1
States / cities
Minnetonka, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 26, 2026, 2:14 PM EDT
Completed Phase 2 Interventional Results available

Chemotherapy, Irradiation, Cell Infusions, and Interleukin-2 to Treat Metastatic Melanoma

NCT00314106
View directory record Official record
Conditions
Metastatic Melanoma
Interventions
Melanoma Reactive TIL, Cyclophosphamide, IL-2, Fludarabine, 1200 total body irradiation (TBI)
Biological · Drug · Radiation
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 18, 2012 · Synced Oct 26, 2026, 2:14 PM EDT
Not listed Not applicable Interventional

Combined Constraint Therapy and Bimanual Therapy for Children With Unilateral Brain Injury

NCT02840643
View directory record Official record
Conditions
Hemiplegia, Cerebral Palsy
Interventions
Bimanual hand therapy, Constraint therapy
Behavioral
Lead sponsor
Blythedale Children's Hospital
Other
Eligibility
4 Years to 17 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2023
U.S. locations
1
States / cities
Valhalla, New York
Source: ClinicalTrials.gov public record
Updated Jan 10, 2022 · Synced Oct 26, 2026, 2:14 PM EDT
Completed Not applicable Interventional Results available

LINK: Aftercare Monitoring Project

NCT00265512
View directory record Official record
Conditions
Alcohol Dependence, Drug Dependence
Interventions
Telephone Case Monitoring, Continuing Care as Usual
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
667 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
3
States / cities
Palo Alto, California • Topeka, Kansas • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 16, 2019 · Synced Oct 26, 2026, 2:14 PM EDT
Withdrawn Phase 4 Interventional

Comparison of ARNI to Alternate Oral Vasodilator Therapies in Patients With Low Cardiac Output

NCT04206865
View directory record Official record
Conditions
Cardiogenic Shock
Interventions
Sacubitril-Valsartan, Standard Oral Vasodilators
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Oct 26, 2026, 2:14 PM EDT
Completed Not applicable Interventional

An Outcome Evaluation of the Project CHANGE-MS Violence Intervention Program

NCT04567381
View directory record Official record
Conditions
Violence, Recidivism
Interventions
Enhanced Services, Treatment as Usual
Other
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Male only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 14, 2022 · Synced Oct 26, 2026, 2:14 PM EDT
Terminated Not applicable Interventional Results available

Remote Preconditioning Over Time To Empower Cerebral Tissue

NCT02169739
View directory record Official record
Conditions
Ischemic Stroke, Cerebral Small Vessel Disease, Cognitive Decline
Interventions
Ischemic Preconditioning
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
40 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Oct 26, 2026, 2:14 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

MISC-IPV: A Community-Based Intervention for Children Traumatized by Intimate Partner Violence

NCT05948631
View directory record Official record
Conditions
MISC Intervention, Treatment as Usual
Interventions
MISC intervention, Treatment as Usual (TAU)
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
7 Years to 65 Years
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 26, 2026, 2:14 PM EDT
Completed Phase 2 Interventional Results available

TBTC Study 29: Rifapentine During Intensive Phase Tuberculosis (TB) Treatment

NCT00694629
View directory record Official record
Conditions
Pulmonary Tuberculosis
Interventions
rifapentine, rifapentine 10 mg/kg, rifapentine 15 mg/kg, rifapentine 20 mg/kg
Drug
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years and older
Enrollment
334 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
23
States / cities
Little Rock, Arkansas • Los Angeles, California • San Diego, California + 16 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 26, 2026, 2:14 PM EDT
Completed Not applicable Interventional Results available

Diabetes Data-Assisted Remission Trial (DDART)

NCT04663061
View directory record Official record
Conditions
Type 2 Diabetes, Obesity
Interventions
Medical weight loss, Diabetes education, Continuous glucose monitoring
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 26, 2026, 2:14 PM EDT
Not listed Phase 2 Interventional

Study of Patients With Body Image Issues Treated With 2 Different Behavioral Interventions

NCT01316627
View directory record Official record
Conditions
Body Dysmorphic Disorders
Interventions
Crooked Mirror Externalization Therapy, Mirror Retraining Method
Behavioral
Lead sponsor
Westwood Institute for Anxiety Disorders, Inc
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 16, 2011 · Synced Oct 26, 2026, 2:14 PM EDT
Completed Phase 4 Interventional Results available

A Comparative Effectiveness RCT of Optimized Cessation Treatments

NCT02301403
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine patch, in-person counseling and quitline counseling, Preparation Nicotine Mini-Lozenges, Combination NRT (nicotine patch + nicotine mini-lozenges), Intensive In-Person Cessation Counseling, Extended Maintenance Counseling Calls, Automated Adherence Calls
Drug · Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
623 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 13, 2020 · Synced Oct 26, 2026, 2:14 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Enhancing Smoking Cessation in the Homeless Population

NCT01932996
View directory record Official record
Conditions
Cigarette Smoking, Tobacco Smoking, Smoking, Tobacco
Interventions
nicotine patch plus nicotine gum/lozenge, Intensive Alcohol Intervention
Drug · Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 75 Years
Enrollment
352 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Oct 26, 2026, 2:14 PM EDT
Recruiting No phase listed Observational

Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders

NCT07493096
View directory record Official record
Conditions
Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD), Neurodevelopmental Disorders and Developmental Abnormalities, Developmental Delay (Disorder), Cerebral Palsy (CP), Cerebral Palsy Hemiparetic Cerebral Palsy Spasticity Gait Disorders, Neurologic Postural Balance Impairment, Cerebral Palsy Infantile, Cerebral Palsy Spastic Hemiplegic, Cerebral Palsy, Dyskinetic, Autism Spectrum Disorder, Autism Spectrum Disorder (ASD, Hypoxic Ischemic Encephalopathy, Hypoxic Ischemic Encephalopathy (HIE), Traumatic Brain Injury (TBI), Sensory Processing Disorder, Chromosomal Abnormalities, Genetic Disorders, Down Syndrome (Trisomy 21), Fragile X Syndrome (FXS), RETT Syndrome With Proven MECP2 Mutation, Williams Syndrome, 22q11.2 Deletion Syndrome, Sensorimotor Integration
Interventions
Not listed
Lead sponsor
Healing Hope International
Other
Eligibility
4 Years to 12 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2036
U.S. locations
1
States / cities
The Woodlands, Texas
Source: ClinicalTrials.gov public record
Updated Mar 25, 2026 · Synced Oct 26, 2026, 2:14 PM EDT