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Showing 1–24 of 25 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Internet Intervention + Stepped Care Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

iSIPsmarter: An RCT Evaluating the Efficacy of a Technology-Based Intervention to Reduce Sugary Drinks in Rural Appalachia

NCT05030753
View directory record Official record
Conditions
Diet Habit, Sugar-Sweetened Beverages
Interventions
iSIPsmarter, Patient Education (PE)
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 110 Years
Enrollment
249 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Sep 23, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

TechStep: Technology-based Stepped Care to Stem Transgender Adolescent Risk Transmission

NCT04000724
View directory record Official record
Conditions
HIV
Interventions
Text Messaging (Text+Step), WebApp (App+Step), Information/No Step
Behavioral
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
15 Years to 24 Years
Enrollment
254 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
5
States / cities
Los Angeles, California • Boston, Massachusetts • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2024 · Synced Sep 23, 2026, 11:23 PM EDT
Completed Phase 3 Interventional Results available

Self-Management Program and Survivorship Care Plan in Improving the Health of Cancer Survivors After Stem Cell Transplant

NCT03125070
View directory record Official record
Conditions
Hematopoietic and Lymphoid Cell Neoplasm
Interventions
Best Practice and Internet site with links to existing resources, Internet, Mobile app and Telehealth Intervention, Survey Administration
Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
546 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
15
States / cities
Tampa, Florida • Maywood, Illinois • Kansas City, Kansas + 10 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Sep 23, 2026, 11:23 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

iSIPsmarter: A Pilot RCT to Evaluate a Web-based Behavioral Intervention to Reduce Sugary Beverages Among Black Adults

NCT06184737
View directory record Official record
Conditions
Diet Habit, Sugar-Sweetened Beverages
Interventions
iSIPsmarter, Patient Education (PE)
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 110 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Sep 23, 2026, 11:23 PM EDT
Completed Not applicable Interventional

Internet Intervention for Childhood Encopresis

NCT00767403
View directory record Official record
Conditions
Encopresis
Interventions
Internet Intervention + Stepped Care, Internet Intervention, Patient Education Website
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
5 Years to 12 Years
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 2, 2012 · Synced Sep 23, 2026, 11:23 PM EDT
Completed Not applicable Interventional

Rheumatoid Arthritis Shared Decision Making

NCT05530694
View directory record Official record
Conditions
Rheumatoid Arthritis
Interventions
Clinician communication training, Patient activation, RA Medication summary guide and RA Choice
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
4
States / cities
San Francisco, California • Wilmington, Delaware • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 23, 2026, 11:23 PM EDT
Recruiting Not applicable Interventional

SMARTer Weight Loss Management

NCT05861973
View directory record Official record
Conditions
Obesity
Interventions
Adaptive SMARTer intervention (SMARTer), Diabetes Prevention Program (DPP), Self-Guided Treatment (Self-Guided)
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
492 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 23, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing Inequities in Care of Hypertension, Lifestyle Improvement for Everyone (RICH LIFE Project)

NCT02674464
View directory record Official record
Conditions
Uncontrolled Hypertension
Interventions
Provider Audit-Feedback, Stratified by Race and Ethnicity, Blood Pressure Measurement Standardization, System Level Leadership Intervention, Collaborative Care Team Intervention, Community Health Worker Referral, Specialist Care Consultation
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 100 Years
Enrollment
1,820 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 30, 2022 · Synced Sep 23, 2026, 11:23 PM EDT
Completed Not applicable Interventional Results available

Stepped Telemental Health Care Intervention for Depression

NCT01906476
View directory record Official record
Conditions
Depression
Interventions
Stepped Care, Telephone Cognitive Behavior Therapy
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Sep 23, 2026, 11:23 PM EDT
Completed Not applicable Interventional

A Hybrid Type II Trial of the Optimizing Resilience and Coping With HIV Through Internet Delivery in Ryan White Clinics in Chicago

NCT05123144
View directory record Official record
Conditions
People Living With HIV
Interventions
BHS+ORCHID
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
Not listed
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 23, 2026, 11:23 PM EDT
Completed Not applicable Interventional

Interactive Survivorship Program for the Improvement of Healthcare Resources in Adolescent and Young Adult Cancer Survivors, INSPIRE-AYA Study

NCT04593277
View directory record Official record
Conditions
Clinical Stage I Cutaneous Melanoma AJCC v8, Clinical Stage II Cutaneous Melanoma AJCC v8, Clinical Stage III Cutaneous Melanoma AJCC v8, Hematopoietic and Lymphoid Cell Neoplasm, Invasive Malignant Neoplasm, Leukemia, Lymphoma, Malignant Solid Neoplasm, Sarcoma, Stage I Colorectal Cancer AJCC v8, Stage II Colorectal Cancer AJCC v8, Stage III Colorectal Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Thyroid Gland Carcinoma
Interventions
Internet Mobile Technology, Internet-Based Intervention, Questionnaire Administration, Supportive Care, Informational Intervention
Other · Procedure
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
549 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
5
States / cities
Los Angeles, California • Boston, Massachusetts • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Sep 23, 2026, 11:23 PM EDT
Enrolling by invitation Not applicable Interventional

SHADES Mechanistic Trial

NCT06041581
View directory record Official record
Conditions
Insomnia, Insomnia Chronic, Insomnia, Primary, Sleep Disturbance, Sleep Disorder, Cardiovascular Diseases, Heart Diseases, Coronary Artery Disease, Stroke, Autonomic Dysfunction, Systemic Inflammatory Response, Metabolic Disease
Interventions
Sleep Healthy Using The Internet (SHUTi), Telephonic CBT-I, Face-to-Face CBT-I, Active Control: Sleep Education/Hygiene, Symptom Monitoring, and Usual Primary Care
Behavioral · Other
Lead sponsor
Indiana University
Other
Eligibility
40 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 23, 2026, 11:23 PM EDT
Completed Not applicable Interventional

Stepped Enhancement of PTSD Services Using Primary Care (STEPS UP): A Randomized Effectiveness Trial

NCT01492348
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Depression
Interventions
STEPS UP, OUC
Behavioral
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
666 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
6
States / cities
Fort Carson, Colorado • Fort Stewart, Georgia • Fort Campbell, Kentucky + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 13, 2017 · Synced Sep 23, 2026, 11:23 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

ENhanced Recovery in CHildren Undergoing Surgery

NCT04060303
View directory record Official record
Conditions
Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis
Interventions
Perioperative surgical care
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
10 Years to 18 Years
Enrollment
597 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 23, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Healthy Using The Internet for Older Adult Sufferers of Insomnia and Sleeplessness

NCT03213132
View directory record Official record
Conditions
Insomnia, Sleep Initiation and Maintenance Disorders
Interventions
SHUTi (Sleep Health Using the Internet), Patient Education
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
55 Years and older
Enrollment
311 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Sep 23, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pragmatic Trial of WHT vs. PC-GE to Promote Non-Pharmacological Strategies to Treat Chronic Pain in Veterans

NCT04330365
View directory record Official record
Conditions
Chronic Pain
Interventions
Whole Health Team (WHT) Intervention Arm, Primary Care Group Education (PC-GE) Intervention Arm, Usual Primary Care (UPC) Arm
Behavioral
Lead sponsor
San Francisco Veterans Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
793 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
6
States / cities
San Francisco, California • West Haven, Connecticut • Tampa, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 23, 2026, 11:23 PM EDT
Completed Not applicable Interventional

Sleep To Reduce Incident Depression Effectively

NCT03322774
View directory record Official record
Conditions
Insomnia, Primary, Major Depressive Disorder, Rumination
Interventions
digital Cognitive Behavioral Therapy for Insomnia, face-to-face Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene Education Control
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
1,237 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 30, 2024 · Synced Sep 23, 2026, 11:23 PM EDT
Completed Not applicable Interventional

WebMAP Mobile Self-management of Adolescent Chronic Pain

NCT03332563
View directory record Official record
Conditions
Chronic Pain
Interventions
Cognitive-behavioral intervention for chronic pain
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
10 Years to 17 Years
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
5
States / cities
Hartford, Connecticut • Ann Arbor, Michigan • Kansas City, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2019 · Synced Sep 23, 2026, 11:23 PM EDT
Completed Not applicable Interventional

Web-administered STAIR for Patients on Behavioral Health Waitlists

NCT06431022
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
webSTAIR, CHW coaching
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 23, 2026, 11:23 PM EDT
Completed Not applicable Interventional

Web-based Collaborative Care Intervention Study

NCT02939755
View directory record Official record
Conditions
Cancer, Depression, Fatigue, Pain
Interventions
Stepped collaborative care intervention, Enhanced Usual Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years to 100 Years
Enrollment
459 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
7
States / cities
Monroeville, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 15, 2024 · Synced Sep 23, 2026, 11:23 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Lombardi Comprehensive Cancer Center/Legacy Pilot Study to Reduce Adverse Smoking Outcomes in the Context of Lung Cancer Screening

NCT02267096
View directory record Official record
Conditions
Smoking, Lung Cancer
Interventions
Telephone Counseling, Minimal Treatment
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
55 Years to 80 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Burlington, Massachusetts • Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 18, 2016 · Synced Sep 23, 2026, 11:23 PM EDT
Completed Not applicable Interventional

MoodHelper: Internet Cognitive Behavioral Therapy (CBT) for Depression

NCT01379027
View directory record Official record
Conditions
Depression
Interventions
Pure self-help Internet CBT for depression, Guided self-help Internet CBT, Stepped-Care Internet CBT condition
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
1,816 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 7, 2018 · Synced Sep 23, 2026, 11:23 PM EDT
Completed Phase 2 Interventional Results available

eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risk

NCT04437485
View directory record Official record
Conditions
Depression, Major Depressive Disorder, Dysthymic Disorder, Depressive Symptoms, Type 2 Diabetes, PreDiabetes, Insulin Resistance
Interventions
Good Days Ahead (GDA), Problem Solving Treatment in Primary Care (PST-PC), Antidepressant Medications, Active Control
Behavioral · Drug · Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Sep 23, 2026, 11:23 PM EDT
Recruiting Phase 3 Interventional

Tobacco Education and Lung Health Study (TEAL)

NCT06290869
View directory record Official record
Conditions
Smoking Cessation
Interventions
Phone-based Tobacco Treatment, Nicotine Replacement, and Stepped Care Intervention, E-Referral to the Tobacco Quitline
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
50 Years to 80 Years
Enrollment
1,188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 23, 2026, 11:23 PM EDT