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Showing 1–24 of 30 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Interpersonal Psychotherapy for Depressed Adolescents Clear all
Completed Phase 1Phase 2 Interventional

The Efficacy of Parent Involvement in the Treatment of Adolescent Depression

NCT00883519
View directory record Official record
Conditions
Major Depressive Disorder, Dysthymic Disorder, Depressive Disorder NOS, Adjustment Disorder
Interventions
Interpersonal Psychotherapy for Depressed Adolescents, Interpersonal Psychotherapy for Depressed Adolescents and Parents
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
12 Years to 17 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 12, 2012 · Synced Sep 28, 2026, 6:13 PM EDT
Completed Not applicable Interventional

IPT-A for Adolescents With PTSD Symptoms

NCT03795818
View directory record Official record
Conditions
PTSD
Interventions
Interpersonal Psychotherapy for Adolescents
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
13 Years to 18 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 1, 2024 · Synced Sep 28, 2026, 6:13 PM EDT
Completed Not applicable Interventional

Comparison of Three Therapy-Based Interventions for Preventing Depression in Adolescents

NCT00258752
View directory record Official record
Conditions
Depression
Interventions
IPT-AST, Enhanced IPT-AST, School counseling
Behavioral · Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
11 Years to 17 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
2
States / cities
Piscataway, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 7, 2020 · Synced Sep 28, 2026, 6:13 PM EDT
Completed Phase 1 Interventional Results available

Interpersonal Psychotherapy for Depressed Adolescents Engaging in Non-suicidal Self-injury

NCT00401102
View directory record Official record
Conditions
Depression, Self-injurious Behavior
Interventions
Interpersonal Psychotherapy for Depressed Adolescents
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
12 Years to 18 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 27, 2013 · Synced Sep 28, 2026, 6:13 PM EDT
Completed Not applicable Interventional

The Efficacy of a Depression Intervention for Adolescents With Depression and Sleep Disturbances

NCT02429674
View directory record Official record
Conditions
Depression
Interventions
TranS-C and IPT-A
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
12 Years to 17 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 31, 2021 · Synced Sep 28, 2026, 6:13 PM EDT
Not listed Not applicable Interventional

Depression in Youth Onset Type 2 Diabetes

NCT06285487
View directory record Official record
Conditions
Type 2 Diabetes, Depression
Interventions
Group Program
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 28, 2024 · Synced Sep 28, 2026, 6:13 PM EDT
Completed Phase 2 Interventional Results available

An Adaptive Algorithm-Based Approach to Treatment for Adolescent Depression

NCT03222570
View directory record Official record
Conditions
Depressive Disorder
Interventions
Interpersonal Psychotherapy for Depressed Adolescents, Selective Serotonin Reuptake Inhibitor, Usual Care
Behavioral · Drug · Other
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years to 18 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Sep 28, 2026, 6:13 PM EDT
Completed Not applicable Interventional Results available

Feasibility and Acceptability of W-GenZD vs CBT-light Teletherapy for Adolescents Seeking Mental Health Services

NCT05372913
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Woebot for Adolescents (W-GenZD) Mobile Application, CBT-Lite Teletherapy Group
Device · Behavioral
Lead sponsor
Woebot Health
Industry
Eligibility
13 Years to 17 Years
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Sep 28, 2026, 6:13 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Preventing Obesity in Military Communities-Adolescents

NCT02671292
View directory record Official record
Conditions
Obesity, Overweight, Binge Eating
Interventions
Interpersonal Psychotherapy, Health Education
Behavioral · Other
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
12 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 25, 2019 · Synced Sep 28, 2026, 6:13 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Middle School to High School Transition Project: Depression and Substance Abuse Prevention

NCT00071513
View directory record Official record
Conditions
Depression, Substance-Related Disorders
Interventions
CAST-T/HSTS, Brief Intervention
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
12 Years to 15 Years
Enrollment
497 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 16, 2016 · Synced Sep 28, 2026, 6:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interpersonal Psychotherapy for Adolescent Girls

NCT01534377
View directory record Official record
Conditions
Depression
Interventions
Interpersonal Psychotherapy for Adolescents, Enhanced Care
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
13 Years to 15 Years · Female only
Enrollment
328 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2018
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 2, 2018 · Synced Sep 28, 2026, 6:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Engaging Black Youth in Depression and Suicide Prevention Treatment Within Urban Schools

NCT03940508
View directory record Official record
Conditions
Depression, Suicidal Ideation
Interventions
Making Connections Intervention, IPT-A
Behavioral
Lead sponsor
New York University
Other
Eligibility
12 Years to 20 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 14, 2025 · Synced Sep 28, 2026, 6:13 PM EDT
Completed Phase 1Phase 2 Interventional Results available

An Adaptive Treatment Strategy for Adolescent Depression

NCT01802437
View directory record Official record
Conditions
Adolescent Depression
Interventions
Fluoxetine, Increased Dose of Interpersonal Psychotherapy, Continue to Receive Initial Dose of Interpersonal Psychotherapy
Drug · Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 10, 2019 · Synced Sep 28, 2026, 6:13 PM EDT
Completed Phase 2Phase 3 Interventional

A Stepped Care Model of Adolescent Depression Treatment in Primary Care

NCT01443715
View directory record Official record
Conditions
Major Depressive Disorder, Dysthymia
Interventions
Stepped Care IPT-A (SCIPT-A), Treatment as Usual
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
13 Years to 20 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 3, 2014 · Synced Sep 28, 2026, 6:13 PM EDT
Completed Not applicable Interventional

School Adolescent Mood Project: Efficacy of IPT-AST in Schools

NCT04109716
View directory record Official record
Conditions
Depressive Symptoms
Interventions
Interpersonal Psychotherapy - Adolescent Skills Training, Services as usual
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
14 Years to 75 Years
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced Sep 28, 2026, 6:13 PM EDT
Recruiting Not applicable Interventional

Improving Mood for Adolescents Through Teaming With End-Users in Routine Care (The iMATTER Project)

NCT07020572
View directory record Official record
Conditions
Depressive Symptoms
Interventions
Brief Interpersonal Psychotherapy - Adolescent Skills Training (B-IPT-AST), Services as usual (SAU)
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
13 Years to 17 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 28, 2026, 6:13 PM EDT
Completed Phase 1Phase 2 Interventional Results available

An Adaptive Treatment Strategy for Adolescent Depression-Continuation

NCT02017535
View directory record Official record
Conditions
Adolescent Depression
Interventions
Fluoxetine, Interpersonal Psychotherapy
Drug · Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years to 18 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 22, 2020 · Synced Sep 28, 2026, 6:13 PM EDT
Completed Not applicable Interventional

Interpersonal Psychotherapy for Youth With Severe Mood Dysregulation

NCT01962623
View directory record Official record
Conditions
Severe Mood Dysregulation
Interventions
IPT-MBD
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
12 Years to 17 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 23, 2017 · Synced Sep 28, 2026, 6:13 PM EDT
Completed Phase 3 Interventional

A Clinical Trial of IPT-A to Prevent Suicide in Depressed Adolescents With Suicidal Behavior

NCT01447602
View directory record Official record
Conditions
Unipolar Depression, Dysthymia
Interventions
IPT-A
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
12 Years to 19 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 3, 2014 · Synced Sep 28, 2026, 6:13 PM EDT
Completed Not applicable Interventional Results available

Early Detection and Prevention of Mood Disorders in Children of Parents With Bipolar Disorder

NCT00338806
View directory record Official record
Conditions
Bipolar Disorder, Depression
Interventions
Interpersonal psychotherapy for prevention with adolescents, Educational clinical monitoring
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
12 Years to 17 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 14, 2017 · Synced Sep 28, 2026, 6:13 PM EDT
Completed Not applicable Interventional

Collaborative Adolescent Research on Emotions and Suicide

NCT01528020
View directory record Official record
Conditions
Suicidal and Self-injurious Behaviour
Interventions
Dialectical Behavior Therapy, Individual and Group Supportive Therapy
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
13 Years to 17 Years
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 16, 2016 · Synced Sep 28, 2026, 6:13 PM EDT
Completed Not applicable Interventional Results available

Self-guided Treatment for Adolescents Navigating Depression

NCT05462652
View directory record Official record
Conditions
Depressive Symptoms, Depression, Depressive Disorder, Depressive Episode
Interventions
Active Intervention
Device
Lead sponsor
Limbix Health, Inc.
Industry
Eligibility
13 Years to 21 Years
Enrollment
223 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2024 · Synced Sep 28, 2026, 6:13 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Just-in-Time Training for Youth Mentors

NCT07129070
View directory record Official record
Conditions
Mental Health Issue, Depression, Anxiety
Interventions
Interpersonal Psychotherapy-Adolescent Skills Training via Just-In-Time Training (JITT) implementation strategy, Interpersonal Psychotherapy-Adolescent Skills Training (IPT-AST) implemented via usual training
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years and older
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 28, 2026, 6:13 PM EDT
Completed Not applicable Interventional

Digital Therapeutic vs Psychoeducation for Management of Mild to Moderate Depression in Adolescents

NCT04985331
View directory record Official record
Conditions
Depression, Teen
Interventions
W-GenZD
Device
Lead sponsor
Woebot Health
Industry
Eligibility
16 Years to 17 Years
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 4, 2022 · Synced Sep 28, 2026, 6:13 PM EDT