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Showing 1–18 of 18 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Interpersonal and Social Rhythms Therapy Clear all
Recruiting Phase 2 Interventional

Correcting Circadian Rhythms to Breakthrough in Bipolar Disorder

NCT06226025
View directory record Official record
Conditions
Bipolar Disorder, Delayed Sleep-Wake Phase Disorder
Interventions
Melatonin, Placebo, Behavioral sleep intervention, Behavioral sleep control
Drug · Other · Behavioral
Lead sponsor
Leslie Swanson
Other
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Sep 25, 2026, 6:43 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Early Intervention for Youth at High Risk for Bipolar Disorder

NCT04815239
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Interpersonal and Social Rhythm Therapy (IPSRT), The Healthy Lifestyle Behavior Intervention (HL)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 18 Years
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 25, 2026, 6:43 AM EDT
Completed Not applicable Interventional

Sleep Intervention in Young Boys with Duchenne Muscular Dystrophy

NCT04529707
View directory record Official record
Conditions
Duchenne Muscular Dystrophy
Interventions
Transdiagnostic Behavioral Sleep Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
6 Years to 18 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 6, 2025 · Synced Sep 25, 2026, 6:43 AM EDT
Completed Not applicable Interventional Results available

A Trial of Group Psychotherapy for Veterans and Military Personnel With Post Traumatic Stress Disorder (PTSD)

NCT00984698
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depression, Insomnia Disorder
Interventions
Cognitive Behavioral Social Rhythm Group Therapy, Present Centered Group Therapy
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 30, 2014 · Synced Sep 25, 2026, 6:43 AM EDT
Recruiting Not applicable Interventional

Suicidal Behavior in Patients Diagnosed With Bipolar Disorder

NCT02604277
View directory record Official record
Conditions
Depression, Alcoholism, Drug Abuse
Interventions
Interpersonal and Social Rhythm Therapy (ISRT), Bipolar-Specific Cognitive Behavioral Therapy (CBT), Mindfulness-Based Stress Reduction (MBSR), Psycho-education & Understanding Bipolar Medications Therapy
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 64 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 25, 2026, 6:43 AM EDT
Completed Not applicable Interventional

Pilot Study of Interpersonal and Social Rhythm Therapy for Subthreshold Bipolar

NCT01520129
View directory record Official record
Conditions
Bipolar Disorder NOS
Interventions
Interpersonal and social rhythm therapy
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Sep 25, 2026, 6:43 AM EDT
Terminated Not applicable Interventional

Adjunctive Psychotherapy for Perinatal Bipolar Disorder

NCT02402738
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Interpersonal and Social Rhythm Therapy, Enhanced Treatment as Usual
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 15, 2019 · Synced Sep 25, 2026, 6:43 AM EDT
Completed Not applicable Interventional

Interpersonal and Social Rhythm Therapy for Adolescents With Bipolar Disorder

NCT00576355
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Interpersonal and Social Rhythm Therapy for Adolescents (IPSRT-A), Treatment As Usual (TAU)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
12 Years to 19 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 19, 2012 · Synced Sep 25, 2026, 6:43 AM EDT
Completed Not applicable Interventional

Early Assessment and Intervention for Adolescents at Risk for Bipolar Disorder

NCT03203707
View directory record Official record
Conditions
Bipolar Disorder, Early Intervention
Interventions
Interpersonal and Social Rhythm Therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Sep 25, 2026, 6:43 AM EDT
Completed Phase 4 Interventional Results available

Acute Psychotherapy for Bipolar II Depression

NCT01133821
View directory record Official record
Conditions
Bipolar Disorder, Depression
Interventions
IPSRT plus placebo (IPSRT-PLA), IPSRT plus quetiapine
Drug
Lead sponsor
Holly Swartz
Other
Eligibility
18 Years to 65 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 8, 2018 · Synced Sep 25, 2026, 6:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Social & Behavioral Rhythms in Chronic Pain

NCT03022643
View directory record Official record
Conditions
Chronic Pain
Interventions
Interpersonal Social Rhythms Psychotherapy, Bright Light Device
Behavioral · Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 65 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 14, 2019 · Synced Sep 25, 2026, 6:43 AM EDT
Withdrawn Not applicable Interventional

Optimizing Cardiac Rehabilitation by Integrating Sleep Therapeutics

NCT04506112
View directory record Official record
Conditions
Sleep Wake Disorders, Sleep Disturbance, Sleep-Related Impairment
Interventions
Transdiagnostic Sleep and Circadian Intervention (TranS-C), adapted for cardiac rehabilitation
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Sep 25, 2026, 6:43 AM EDT
Completed Not applicable Interventional

Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)

NCT00012558
View directory record Official record
Conditions
Bipolar Disorder
Interventions
lithium, valproate, bupropion, paroxetine, lamotrigine, risperidone, inositol, tranylcypromine, Cognitive Behavioral Therapy, Family-focused Therapy, Interpersonal and Social Rhythms Therapy
Drug · Behavioral
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
15 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2005
U.S. locations
11
States / cities
Stanford, California • Denver, Colorado • Boston, Massachusetts + 8 more
Source: ClinicalTrials.gov public record
Updated May 3, 2007 · Synced Sep 25, 2026, 6:43 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Psychotherapy for Bipolar II Depression, Pilot Study, Phase II

NCT00411463
View directory record Official record
Conditions
Bipolar II Disorder
Interventions
Interpersonal and Social Rhythm Therapy (IPSRT-BPII), Seroquel
Behavioral · Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 29, 2017 · Synced Sep 25, 2026, 6:43 AM EDT
Withdrawn Not applicable Interventional

Pilot Study of the Effects of Circadian Rhythms on the Treatment of Bipolar I Depression.

NCT00726154
View directory record Official record
Conditions
Bipolar Disorder
Interventions
IPSRT, Collaborative Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 10, 2012 · Synced Sep 25, 2026, 6:43 AM EDT
Completed Not applicable Interventional Results available

Triple Vulnerability? Circadian Tendency, Sleep Deprivation and Adolescence

NCT01828320
View directory record Official record
Conditions
Eveningness/Sleep
Interventions
Cognitive Behavior Therapy for Insomnia, Interpersonal and Social Rhythms Therapy, Chronotherapy, Psychoeducation
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
10 Years to 18 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Sep 1, 2025 · Synced Sep 25, 2026, 6:43 AM EDT
Completed Phase 4 Interventional

Psychosocial Therapy Plus Maintenance Pharmacotherapy for Treating Bipolar Disorder

NCT00227968
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Interpersonal Social Rhythm Therapy (IPSRT), Clinical Status and Symptom Response Therapy (CSSRT)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1995 – 2002
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 24, 2013 · Synced Sep 25, 2026, 6:43 AM EDT
Completed Not applicable Interventional

Improving Memory for Sleep Treatment Content With Text Messages

NCT02961400
View directory record Official record
Conditions
Sleep Wake Disorders
Interventions
PUSH text messages, PULL text messages, TranS-C, PE
Other · Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
10 Years to 18 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Oct 28, 2019 · Synced Sep 25, 2026, 6:43 AM EDT