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Showing 1–17 of 17 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Intragastric Balloon Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Studying the Hedonic and Homeostatic Regulation of Food Intake Using Functional MRI

NCT05525845
View directory record Official record
Conditions
Healthy
Interventions
Functional Magnetic Resonance Imaging (pCASL-MRI), Intragastric Balloon, Elemental Meal, Hedonic Meal
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years to 50 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Sep 3, 2026, 5:51 AM EDT
Terminated Not applicable Interventional

How Gas-Filled Intragastric Balloons or Endoscopic Sleeve Gastroplasty Affect Hunger, Hunger Hormones, and Gastric Emptying Compared to Meal Replacements

NCT04306445
View directory record Official record
Conditions
Obesity
Interventions
GF-IGB: Obalon Balloon, Medically Supervised Meal Replacement Program: My New Weigh, Endoscopic sleeve gastroplasty: (ESG)
Device · Dietary Supplement · Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
22 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 3, 2026, 5:51 AM EDT
Terminated Not applicable Interventional Results available

Endoscopic Intragastric Balloon Placement for Weight Loss in Liver Transplant Waitlist Candidates

NCT02556138
View directory record Official record
Conditions
Obesity, Liver Cirrhosis
Interventions
ORBERA Intragastric Balloon
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 29, 2018 · Synced Sep 3, 2026, 5:51 AM EDT
Active, not recruiting Not applicable Interventional

Evaluation of Bariatric Endoscopic Antral Myotomy (BEAM) as a Treatment for Obesity

NCT05713071
View directory record Official record
Conditions
Obesity, Weight Loss, Delayed Gastric Emptying Following Procedure, Obesity, Mild, Obesity, Morbid, Obesity; Excess Calories
Interventions
Bariatric Endoscopic Antral Myotomy
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 3, 2026, 5:51 AM EDT
Active, not recruiting No phase listed Observational

Biological Sample Repository for Gastrointestinal Disorders

NCT05874726
View directory record Official record
Conditions
Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder, Overweight and Obesity, Overweight, Overweight or Obesity, Diabetes Type 2, Diabetes Mellitus, Diabetes Mellitus, Type 2, Hypertension, Hyperlipidemias, Sleep Apnea, GERD, Gastroesophageal Reflux, Musculoskeletal Pain Disorder, Cancer
Interventions
Blood Collection, Urine Collection, Tissue Sample Collection
Diagnostic Test
Lead sponsor
Pichamol Jirapinyo, MD, MPH
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 3, 2026, 5:51 AM EDT
Recruiting No phase listed Observational

Efficacy and Safety of Endoscopic Antral Myotomy as a Novel Weight Loss Procedure

NCT05711758
View directory record Official record
Conditions
Obesity, Obesity, Morbid, Obesity, Primary, Metabolic Disease, Delayed Gastric Emptying Following Procedure
Interventions
PSAM Treatment Patients
Procedure
Lead sponsor
Christopher C. Thompson, MD, MSc
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Sep 3, 2026, 5:51 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Spatz3 Adjustable Balloon System® (Spatz3) Post Approval Study

NCT05086302
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
Spatz FGIA, Inc
Other
Eligibility
22 Years to 65 Years
Enrollment
537 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
20
States / cities
Marina del Rey, California • Jupiter, Florida • Tampa, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated May 29, 2025 · Synced Sep 3, 2026, 5:51 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Use of EndoFLIP and Manometry Prior to G-POEM

NCT04844190
View directory record Official record
Conditions
Gastroparesis
Interventions
EndoFLIP, Antroduodenal Manometry
Diagnostic Test
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Sep 3, 2026, 5:51 AM EDT
Completed Not applicable Interventional Results available

A Prospective, Randomized Multicenter Study to Evaluate the Safety and Efficacy of the ReShape Duo™ Intragastric Balloon System in Obese Subjects

NCT01673698
View directory record Official record
Conditions
Obesity
Interventions
ReShape Duo balloon, Diet counseling, Exercise counseling
Device · Other
Lead sponsor
ReShape Lifesciences
Industry
Eligibility
21 Years to 60 Years
Enrollment
326 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
8
States / cities
Scottsdale, Arizona • Dalton, Georgia • Marquette, Michigan + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 6, 2015 · Synced Sep 3, 2026, 5:51 AM EDT
Enrolling by invitation No phase listed Observational

Short and Long Term Clinical and Patient-Reported Outcomes Associated With Intragastric Balloon Placement in Patients With Nonalcoholic Fatty Liver Disease

NCT07493967
View directory record Official record
Conditions
NAFLD
Interventions
Not listed
Lead sponsor
Methodist Health System
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 3, 2026, 5:51 AM EDT
Enrolling by invitation No phase listed Observational

Endoscopic Metabolic and Bariatric Therapies

NCT05725967
View directory record Official record
Conditions
Obesity, Obesity, Morbid, Obesity Associated Disorder, Bariatric Surgery Candidate, Fistula, Gastric, Roux-en-y Anastomosis Site, Ulcer, Gastric, Abdominal Pain, Abdominal Obesity, Complication of Surgical Procedure, Complication of Treatment, Complication,Postoperative, Weight Gain, Weight Loss, Leak, Anastomotic, Delayed Gastric Emptying Following Procedure
Interventions
Primary Obesity Endoscopic Procedures, Endoscopic Revision of Bariatric Surgical Procedures, Bariatric Surgery Procedures, Endoscopic Sleeve Gastroplasty, Trans-oral Outlet Reduction, Intragastric Balloon, Primary obesity surgery endoluminal, Restorative obesity surgery endoluminal, Argon Plasma Coagulation, Gastroplasty with Endoscopic Myotomy, Bariatric Endoscopic Antral Myotomy, Pylorus Sparing Antral Myotomy, Aspiration Therapy
Procedure · Device
Lead sponsor
Christopher C. Thompson, MD, MSc
Other
Eligibility
18 Years to 80 Years
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 3, 2026, 5:51 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Obalon Navigation/Touch System Post-Approval Study

NCT04095481
View directory record Official record
Conditions
Obesity
Interventions
Obalon Navigation/Touch System
Device
Lead sponsor
Obalon Therapeutics, Inc.
Industry
Eligibility
22 Years and older
Enrollment
1,600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
2
States / cities
Flower Mound, Texas • Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Dec 22, 2019 · Synced Sep 3, 2026, 5:51 AM EDT
Completed Not applicable Interventional Results available

A Study of BioEnterics® Intragastric Balloon (BIB®) System to Assist in the Weight Management of Obese Subjects

NCT00730327
View directory record Official record
Conditions
Obesity
Interventions
BioEnterics® Intragastric Balloon, Behavioral modification
Device · Other
Lead sponsor
Apollo Endosurgery, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
448 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Nov 5, 2015 · Synced Sep 3, 2026, 5:51 AM EDT
Completed Not applicable Interventional Results available

Spatz Adjustable Balloon for Obesity (SABO)

NCT02812160
View directory record Official record
Conditions
Obesity
Interventions
Spatz3 Adjustable Balloon
Device
Lead sponsor
Spatz FGIA, Inc
Other
Eligibility
22 Years to 65 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
7
States / cities
Chicago, Illinois • Metairie, Louisiana • Towson, Maryland + 4 more
Source: ClinicalTrials.gov public record
Updated May 27, 2021 · Synced Sep 3, 2026, 5:51 AM EDT
Completed Not applicable Interventional Results available

Obalon Balloon System Pivotal IDE (SMART) Trial

NCT02235870
View directory record Official record
Conditions
Obesity
Interventions
Obalon Intragastric Balloons, Sham Device, Nutrition and Lifestyle Program
Device · Behavioral
Lead sponsor
Obalon Therapeutics, Inc.
Industry
Eligibility
22 Years to 64 Years
Enrollment
711 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
15
States / cities
Scottsdale, Arizona • Anaheim, California • Coronado, California + 12 more
Source: ClinicalTrials.gov public record
Updated Mar 7, 2018 · Synced Sep 3, 2026, 5:51 AM EDT
Completed Not applicable Interventional Results available

Intragastric Balloon in Obese Adolescents With Comorbidities

NCT03233048
View directory record Official record
Conditions
Obesity
Interventions
ORBERA™ Intragastric Balloon
Device
Lead sponsor
Imad Absah
Other
Eligibility
14 Years to 17 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 2, 2022 · Synced Sep 3, 2026, 5:51 AM EDT
Recruiting Not applicable Interventional

Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial

NCT06138821
View directory record Official record
Conditions
Obesity, Liver Diseases, Liver Fibrosis, Liver Fat, Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis, MASLD, MASH, Weight Loss, Insulin Resistance, Insulin Sensitivity, Insulin Sensitivity/Resistance, Metabolic Disease, Diabetes, Diabetes Mellitus, Type 2, NASH With Fibrosis, Non-Alcoholic Fatty Liver Disease, Non Alcoholic Fatty Liver, Non-alcoholic Steatohepatitis
Interventions
ESG + lifestyle modification, Lifestyle modification
Device · Behavioral
Lead sponsor
Pichamol Jirapinyo, MD, MPH
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 3, 2026, 5:51 AM EDT