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ClinicalTrials.gov public records Last synced Sep 7, 2026, 12:37 PM EDT

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Showing 1–20 of 20 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Intramuscular electrodes Clear all
Completed Phase 4 Interventional

Gait Training For Acute Stroke: Functional Neuromuscular Stimulation (FNS) and Weight Supported Treadmill Training

NCT00101543
View directory record Official record
Conditions
Stroke
Interventions
Electrical Stimulation with Intramuscular Electrodes, Body Weight Supported Treadmill Training
Device · Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 4, 2009 · Synced Sep 7, 2026, 12:37 PM EDT
Recruiting Not applicable Interventional

Implant for Walking After Incomplete SCI

NCT06965127
View directory record Official record
Conditions
Spinal Cord Injury (SCI), Gait
Interventions
NNP-LE
Device
Lead sponsor
Louis Stokes VA Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Sep 7, 2026, 12:37 PM EDT
Completed No phase listed Observational

Diaphragm Pacing After Spinal Cord Injury

NCT02556125
View directory record Official record
Conditions
Injuries, Spinal Cord
Interventions
Diaphragm pacing
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
2
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 12, 2020 · Synced Sep 7, 2026, 12:37 PM EDT
Completed Phase 2 Interventional

Diaphragm Pacing System (DPS) In Participants With Amyotrophic Lateral Sclerosis (ALS)

NCT01938495
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis (ALS)
Interventions
NeuRx® Diaphragm Pacing System™ (DPS)
Device
Lead sponsor
Barrow Neurological Institute
Other
Eligibility
21 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
25
States / cities
Phoenix, Arizona • Los Angeles, California • San Diego, California + 21 more
Source: ClinicalTrials.gov public record
Updated Mar 8, 2023 · Synced Sep 7, 2026, 12:37 PM EDT
Recruiting Not applicable Interventional

Short-term Implanted Electrodes Following Regenerative Peripheral Nerve Surgery for Improving Prosthetic Limb Control Signals

NCT03260400
View directory record Official record
Conditions
Amputation Neuroma, Amputation
Interventions
a bipolar percutaneous intramuscular electromyography electrode
Device
Lead sponsor
University of Michigan
Other
Eligibility
22 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2029
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 7, 2026, 12:37 PM EDT
Completed Not applicable Interventional

Humanitarian Device Exemption Post-Approval Study of NeuRx Diaphragm Pacing System for Amyotrophic Lateral Sclerosis

NCT01605006
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis (ALS)
Interventions
NeuRx Diaphragm Pacing System (DPS)
Device
Lead sponsor
Synapse Biomedical
Industry
Eligibility
21 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
11
States / cities
Los Angeles, California • San Francisco, California • Denver, Colorado + 8 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2020 · Synced Sep 7, 2026, 12:37 PM EDT
Completed No phase listed Observational Results available

Diaphragm Pacing in Individuals With Spinal Cord Injuries

NCT04179799
View directory record Official record
Conditions
Cervical Spinal Cord Injury
Interventions
Diaphragm Pacing
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 29, 2024 · Synced Sep 7, 2026, 12:37 PM EDT
Completed Not applicable Interventional Results available

Electrical Stimulation for Hemiplegic Shoulder Pain

NCT01123382
View directory record Official record
Conditions
Stroke, Shoulder Pain
Interventions
Intramuscular Electrical Stimulator, Outpatient Therapy
Device · Other
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Sep 7, 2026, 12:37 PM EDT
Recruiting Not applicable Interventional

Regenerative Peripheral Nerve Interface for Control of Lower Limb Prostheses

NCT06275282
View directory record Official record
Conditions
Amputation, Prostheses and Implants
Interventions
Intramuscular electrodes
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 75 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Sep 7, 2026, 12:37 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Motor-Point Stimulation for Conditioning the Diaphragm of Patients With Amyotrophic Lateral Sclerosis (ALS)

NCT00420719
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis (ALS)
Interventions
Intramuscular diaphragm electrodes
Device
Lead sponsor
Synapse Biomedical
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
7
States / cities
San Francisco, California • Stanford, California • Jacksonville, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 17, 2009 · Synced Sep 7, 2026, 12:37 PM EDT
Active, not recruiting Not applicable Interventional

Functional and Neuroprotective Effects of Restoring Lower Limb Sensation After Diabetic Peripheral Neuropathy

NCT04658693
View directory record Official record
Conditions
Lower Extremity Amputee, Diabetic Peripheral Neuropathy
Interventions
Implanted Multi contact stimulating electrode and intramuscular electromyography recording electrode
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 7, 2026, 12:37 PM EDT
Completed Not applicable Interventional Results available

Multimodal Treatment for Hemiplegic Shoulder Pain

NCT02893267
View directory record Official record
Conditions
Stroke, Shoulder Pain
Interventions
Peripheral Nerve Stimulation, Physical Therapy, Sham-PT, Sham-PNS
Device · Other
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 89 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
3
States / cities
Chicago, Illinois • Charlotte, North Carolina • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Sep 7, 2026, 12:37 PM EDT
Recruiting Not applicable Interventional

Feasibility of Neural Feedback for Lower Limb Amputees

NCT03409133
View directory record Official record
Conditions
Amputation
Interventions
Stimulating nerve electrodes and intramuscular recording electrodes
Device
Lead sponsor
Louis Stokes VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 7, 2026, 12:37 PM EDT
Withdrawn Phase 4 Interventional

Ertugliflozin Versus Hydrochlorothiazide in Reducing Sympathetic Neural Overactivity in Patients With Hypertension and Recently-diagnosed Type 2 Diabetes.

NCT03640221
View directory record Official record
Conditions
Hypertension, Diabetes Mellitus, Type 2
Interventions
Ertugliflozin, Hydrochlorothiazide 12.5mg, Microneurography, SKNA recordings, Static Handgrip, Post-handgrip forearm vascular occlusion, Testing of the Arterial Baroreflex Function
Drug · Device · Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
35 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 13, 2020 · Synced Sep 7, 2026, 12:37 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Stimulation-Based Modulation of Spinal and Cortical Sensory Pathways

NCT07401186
View directory record Official record
Conditions
Stroke, Able Bodied
Interventions
Bipolar Neural Stimulation Electrode
Device
Lead sponsor
Peter C. Gerszten, MD
Other
Eligibility
21 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 7, 2026, 12:37 PM EDT
Completed Not applicable Interventional Results available

Peripheral Nerve Stimulation for Shoulder Pain: Dose Response

NCT02928055
View directory record Official record
Conditions
Stroke, Shoulder Pain
Interventions
Peripheral Nerve Stimulation
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 89 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 17, 2021 · Synced Sep 7, 2026, 12:37 PM EDT
Completed Not applicable Interventional Results available

Feasibility and Practice Characteristics of FNS and Gait Robot

NCT00508755
View directory record Official record
Conditions
Stroke
Interventions
Gait Robot, Functional Neuromuscular stimulation with intramuscular electrodes
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 24, 2014 · Synced Sep 7, 2026, 12:37 PM EDT
Active, not recruiting Not applicable Interventional

Implant for Walking After Stroke

NCT05740540
View directory record Official record
Conditions
Stroke, Hemiplegia, Gait, Hemiplegic
Interventions
IRS-8, IST 12 & IST 16
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 7, 2026, 12:37 PM EDT
Completed Phase 4 Interventional

Rapid Antidepressant Improvement Secondary to Excitatory Brain Responses

NCT04276259
View directory record Official record
Conditions
Major Depressive Disorder, Depression
Interventions
Buprenorphine, Naltrexone, Oral Placebo, IM Placebo, Theta burst stimulation (TBS) of the ventromedial prefrontal cortex.
Drug · Device
Lead sponsor
Marta Peciña, MD PhD
Other
Eligibility
18 Years to 55 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 7, 2026, 12:37 PM EDT
Completed Phase 4 Interventional Results available

Imaging of 3D Innervation Zone Distribution in Spastic Muscles From High-density Surface EMG Recordings

NCT03302741
View directory record Official record
Conditions
Spasticity
Interventions
Botulinum neurotoxin (BTX), Physical Therapy, Standard BTX injection (ultrasound guided), 3-dimensional innervation zone (3DIZ) guided injection
Drug · Other · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
21 Years to 75 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Sep 7, 2026, 12:37 PM EDT