- Conditions
- Hypogonadotropic Hypogonadism
- Interventions
- intranasal insulin, placebo (intranasal saline)
- Drug
- Lead sponsor
- Texas Tech University Health Sciences Center
- Other
- Eligibility
- 18 Years to 75 Years · Male only
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 1
- States / cities
- Odessa, Texas
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Showing 25–48
of 24
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Alzheimer's Disease
- Interventions
- Insulin Aspart, Placebo
- Drug
- Lead sponsor
- Jeff Burns, MD
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 31 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2012
- U.S. locations
- 1
- States / cities
- Kansas City, Kansas
- Conditions
- Mild Cognitive Impairment, Alzheimer's Disease
- Interventions
- Regular Insulin, Placebo
- Drug
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 55 Years and older
- Enrollment
- 173 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2011
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment
- Interventions
- Saline, Insulin detemir, Insulin
- Drug
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 50 Years to 89 Years
- Enrollment
- 37 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2015
- U.S. locations
- 2
- States / cities
- Winston-Salem, North Carolina • Tacoma, Washington
- Conditions
- Amnestic Mild Cognitive Impairment, Alzheimer's Disease
- Interventions
- Insulin (Humulin® R U-100), Placebo
- Drug
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 55 Years to 85 Years
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 25
- States / cities
- Phoenix, Arizona • Irvine, California • New Haven, Connecticut + 18 more
- Conditions
- Delirium
- Interventions
- Insulin, Saline
- Drug
- Lead sponsor
- University of Kansas Medical Center
- Other
- Eligibility
- 65 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Kansas City, Kansas
- Conditions
- Type 2 Diabetes, Insulin Sensitivity/Resistance, Cognition, Brain Blood Flow
- Interventions
- Intranasal Insulin, Intranasal Placebo, High Intensity Exercise
- Drug · Behavioral
- Lead sponsor
- Rutgers, The State University of New Jersey
- Other
- Eligibility
- 55 Years to 80 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 4
- States / cities
- New Brunswick, New Jersey • Piscataway, New Jersey
- Conditions
- Type 2 Diabetes Mellitus
- Interventions
- Regular Human Insulin, Placebo
- Drug
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 50 Years to 85 Years
- Enrollment
- 289 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2020
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts
- Conditions
- HIV Dementia, HIV-Associated Cognitive Motor Complex
- Interventions
- Insulin, intranasal, Placebo, intranasal
- Drug
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years to 69 Years
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Spinal Cord Injury
- Interventions
- Regular Insulin, 0.9 % Normal Saline
- Drug · Other
- Lead sponsor
- HealthPartners Institute
- Other
- Eligibility
- 18 Years to 84 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Saint Paul, Minnesota
- Conditions
- Post-operative Cognitive Decline, Post-operative Delirium
- Interventions
- Aspart insulin, Normal saline, Intranasal mucosal atomizer device
- Drug · Device
- Lead sponsor
- Albert Einstein College of Medicine
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 1
- States / cities
- The Bronx, New York
- Conditions
- Parkinson Disease, Multiple System Atrophy
- Interventions
- Intranasal Insulin
- Drug
- Lead sponsor
- Peter Novak
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Worcester, Massachusetts
- Conditions
- Alzheimer Disease
- Interventions
- Empagliflozin, Insulin, Insulin Placebo, Empagliflozin Placebo
- Drug
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 55 Years to 85 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Alcohol Use Disorder
- Interventions
- Regular Human Insulin then Placebo, Placebo then Regular Human Insulin
- Drug
- Lead sponsor
- Brown University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Type 2 Diabetes Mellitus
- Interventions
- Intranasal insulin, Placebo
- Drug
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 50 Years to 85 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2013
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Healthy, Vasodilation, Insulin Resistance, Autonomic Dysfunction, Obesity
- Interventions
- Carbon dioxide breathing, Neurovascular Coupling, Human insulin
- Other · Drug
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 65 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2027
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Type 1 Diabetes
- Interventions
- Insulin, Insulin LISPRO
- Drug
- Lead sponsor
- Hompesch, Marcus, M.D.
- Individual
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- U.S. locations
- 1
- States / cities
- Chula Vista, California
- Conditions
- Frontotemporal Dementia, Behavioral Variant
- Interventions
- Novolin-R insulin
- Drug
- Lead sponsor
- HealthPartners Institute
- Other
- Eligibility
- 41 Years to 89 Years
- Enrollment
- 3 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Saint Paul, Minnesota
- Conditions
- Down Syndrome
- Interventions
- Insulin glulisine, Saline
- Drug
- Lead sponsor
- HealthPartners Institute
- Other
- Eligibility
- 35 Years to 80 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2018
- U.S. locations
- 1
- States / cities
- Saint Paul, Minnesota
- Conditions
- Schizophrenia
- Interventions
- Insulin or Placebo
- Drug
- Lead sponsor
- University of Massachusetts, Worcester
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2010
- U.S. locations
- 1
- States / cities
- Worcester, Massachusetts
- Conditions
- Psychosis, Schizophrenia, Schizo Affective Disorder, Bipolar I Disorder
- Interventions
- Intranasal Insulin
- Drug
- Lead sponsor
- Mclean Hospital
- Other
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 87 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2024
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts
- Conditions
- Mild Cognitive Impairment, Alzheimer's Disease (AD)
- Interventions
- Insulin glulisine, Placebo
- Drug
- Lead sponsor
- HealthPartners Institute
- Other
- Eligibility
- 50 Years to 90 Years
- Enrollment
- 49 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 2
- States / cities
- Minneapolis, Minnesota • Saint Paul, Minnesota
- Conditions
- Stroke
- Interventions
- Intranasal Insulin, Intranasal saline
- Drug
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 40 Years to 89 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Insulin, Exercise
- Interventions
- Placebo into the intranasal mucosa, 20 IU NovoLog Insulin aspart into the intranasal mucosa, 40 IU NovoLog Insulin aspart into the intranasal mucosa, 60 IU NovoLog Insulin aspart into the intranasal mucosa, 80 IU NovoLog Insulin aspart into the intranasal mucosa, 100 IU NovoLog Insulin aspart into the intranasal mucosa, 120 IU NovoLog Insulin aspart into the intranasal mucosa
- Drug
- Lead sponsor
- Michigan State University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 116 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- East Lansing, Michigan