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ClinicalTrials.gov public records Last synced Sep 11, 2026, 5:04 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Intraoperative Imaging Clear all
Completed Phase 2 Interventional Results available

A Study to Evaluate Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Lung Malignancies

NCT05048082
View directory record Official record
Conditions
Lung Cancer
Interventions
pegsitacianine, Tumor resection surgery
Drug · Procedure
Lead sponsor
OncoNano Medicine, Inc.
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 7, 2024 · Synced Sep 11, 2026, 5:04 AM EDT
Not listed No phase listed Observational

Evaluating and Establishing the Relationship in the Five Critical X-ray Time Points in Spinal Deformity Realignment

NCT05154825
View directory record Official record
Conditions
Spine, Spine Deformity
Interventions
Imaging-Observational
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 19, 2024 · Synced Sep 11, 2026, 5:04 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Shear-Wave Elastography

NCT06306976
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
Elective Midline Laparotomy, Imaging: Ultrasound, Tensiometry
Procedure · Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 11, 2026, 5:04 AM EDT
Withdrawn Not applicable Interventional

Intraoperative Imaging of a PET Positive Lymph Node(s) Using 18FDG and a Dual-Mode, Hand-Held Intraoperative Imager

NCT03561324
View directory record Official record
Conditions
Head and Neck Neoplasms
Interventions
Imaging Beta Probe (IBP)
Device
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jan 28, 2020 · Synced Sep 11, 2026, 5:04 AM EDT
Withdrawn Not applicable Interventional

Fluorescence Imaging on the da Vinci Surgical System for Intraoperative Near Infrared Imaging

NCT01104389
View directory record Official record
Conditions
Renal Tumors
Interventions
Fluorescence imaging
Device
Lead sponsor
Intuitive Surgical
Industry
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 25, 2015 · Synced Sep 11, 2026, 5:04 AM EDT
Completed Phase 3 Interventional Results available

Evaluation of Anterior Quadratus Lumborum Block for Postoperative Analgesia in Hip Arthroscopy

NCT03432650
View directory record Official record
Conditions
Hip Disease
Interventions
Bupivacaine + dexamethasone, Ultrasound
Drug · Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 18, 2022 · Synced Sep 11, 2026, 5:04 AM EDT
Terminated Phase 2 Interventional Results available

Ph 2 Intensification Regimen for Previously Untreated, Resectable, Advanced Squamous Cell Cancer

NCT00566540
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
Cisplatin, Paclitaxel, Intensity-Modulated Radiation Therapy (IMRT) External Beam Radiation, Triple endoscopy and biopsy
Drug · Radiation · Procedure
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 25, 2021 · Synced Sep 11, 2026, 5:04 AM EDT
Recruiting Phase 1 Interventional

Pemefolacianine for IMI of Lung Cancer

NCT07772895
View directory record Official record
Conditions
Lung Cancer (Locally Advanced or Metastatic)
Interventions
Pemefolacianine Cohort 1 in Part A, Pemefolacianin Cohort 2 in Part B
Drug
Lead sponsor
Sunil Singhal
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 11, 2026, 5:04 AM EDT
Withdrawn Not applicable Interventional

Feasibility Study of LUM Imaging System for Pancreatic Cancer

NCT04276909
View directory record Official record
Conditions
Pancreatic Cancer
Interventions
LUM Imaging System
Combination Product
Lead sponsor
Lumicell, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Sep 11, 2026, 5:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

PIONEER: Intraoperative and Perioperative OCT Study

NCT02423161
View directory record Official record
Conditions
Retinal Detachment, Epiretinal Membrane, Macular Hole, Fuchs Endothelial Dystrophy
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Sep 11, 2026, 5:04 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Bevonescein to Highlight Nerves in Patients Undergoing Head & Neck Surgery

NCT04420689
View directory record Official record
Conditions
Parotid Neoplasm, Thyroid Neoplasms, Head and Neck Neoplasms, Surgery, Nerve Injury, Imaging
Interventions
Bevonescein
Drug
Lead sponsor
Alume Biosciences, Inc.
Industry
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
3
States / cities
San Diego, California • Stanford, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Sep 11, 2026, 5:04 AM EDT
Completed Phase 2 Interventional Results available

Intraoperative Detection of Residual Cancer in Breast Cancer

NCT03321929
View directory record Official record
Conditions
Breast Cancer
Interventions
LUM Imaging System
Combination Product
Lead sponsor
Lumicell, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
16
States / cities
Mobile, Alabama • Palo Alto, California • New Haven, Connecticut + 13 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2023 · Synced Sep 11, 2026, 5:04 AM EDT
Completed Phase 4 Interventional Results available

Intra-operative Digital vs. Standard Mammography

NCT01766102
View directory record Official record
Conditions
Breast Cancer
Interventions
Intra-operative Mammography, Standard Mammography
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 23, 2017 · Synced Sep 11, 2026, 5:04 AM EDT
Recruiting Phase 1 Interventional

Study of LGW16-03 To Identify Nerves

NCT07385430
View directory record Official record
Conditions
Adults, Open-field Surgery, Major Nerve
Interventions
LGW16-03
Drug
Lead sponsor
Eric R. Henderson
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 11, 2026, 5:04 AM EDT
Not listed Early Phase 1 Interventional

Breast Cancer Margin Delineation Using Polarization Subtraction Imaging Technology

NCT02207179
View directory record Official record
Conditions
Breast Cancer
Interventions
LumaScan Image Guided Surgery
Device
Lead sponsor
LumaMed
Industry
Eligibility
18 Years to 70 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 30, 2015 · Synced Sep 11, 2026, 5:04 AM EDT
Completed No phase listed Observational

Study and Surgical Treatment of Syringomyelia

NCT00011245
View directory record Official record
Conditions
Syringomyelia
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 11, 2026, 5:04 AM EDT
Terminated Not applicable Interventional Results available

Novel Use of an Enhanced Fluoroscopic Imaging Device to Reduce Radiation Exposure and Operative Time During Intramedullary Nailing of Hip Fractures

NCT02856828
View directory record Official record
Conditions
Radiation Exposure
Interventions
DIE
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 14, 2019 · Synced Sep 11, 2026, 5:04 AM EDT
Terminated Phase 2 Interventional

Feasibility Study of Intraoperative Detection of Residual Cancer in Breast Cancer Patients

NCT04440982
View directory record Official record
Conditions
Breast Cancer, Neoadjuvant Therapy
Interventions
LUM015, Lum Imaging System
Drug · Device
Lead sponsor
Lumicell, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
6
States / cities
Palo Alto, California • Clearwater, Florida • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Sep 11, 2026, 5:04 AM EDT
Completed Phase 1 Interventional

Intraoperative Imaging of Pulmonary Nodules by OTL38

NCT02602119
View directory record Official record
Conditions
Neoplasms
Interventions
OTL38
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
262 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 27, 2022 · Synced Sep 11, 2026, 5:04 AM EDT
Recruiting Not applicable Interventional

3-D Tractography FUS Ablation for Essential Tremor

NCT06331052
View directory record Official record
Conditions
Essential Tremor
Interventions
MR-guided Focused Ultrasound Ablation
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
22 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 7, 2026 · Synced Sep 11, 2026, 5:04 AM EDT
Terminated Phase 4 Interventional

Does Fluorescence With or Without Indocyanine Green Improve Parathyroid Identification and Preservation

NCT06169735
View directory record Official record
Conditions
Parathyroid Dysfunction, Adenoma
Interventions
Indocyanine green, SPY Portable Handheld Imaging
Drug · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
417 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 11, 2026, 5:04 AM EDT
Completed Phase 1Phase 2 Interventional

Dose-escalation Study of a Contrast Agent for Delineation of Urological Anatomy in Minimally Invasive Surgery

NCT03106038
View directory record Official record
Conditions
Intraoperative Ureter Injury
Interventions
Nerindocianine for Injection
Drug
Lead sponsor
Li-Cor, Inc.
Industry
Eligibility
19 Years and older · Female only
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 25, 2019 · Synced Sep 11, 2026, 5:04 AM EDT
Completed Not applicable Interventional Results available

Navigation of the Pelvic Floor in Bladder Exstrophy Using Pre-operative MRI

NCT01878500
View directory record Official record
Conditions
Bladder Exstrophy
Interventions
Intraoperative stereotactic imaging with VectorVision
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
Up to 7 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 20, 2021 · Synced Sep 11, 2026, 5:04 AM EDT
Active, not recruiting Not applicable Interventional

Efficacy of IORT With CT-Guided HDR Brachytherapy for Treatment of Breast Cancer

NCT02400658
View directory record Official record
Conditions
Breast Cancer
Interventions
IORT with CT-Guided HDR Brachytherapy
Device
Lead sponsor
Shayna Showalter, MD
Other
Eligibility
45 Years and older · Female only
Enrollment
358 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
3
States / cities
Hackensack, New Jersey • Philadelphia, Pennsylvania • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 24, 2023 · Synced Sep 11, 2026, 5:04 AM EDT