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Completed Phase 1 Interventional

Intrathecal Mafosfamide

NCT00062881
Conditions
Malignant Meningeal Neoplasms
Interventions
Intrathecal Mafosfamide
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
3 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1990 – 2005
U.S. locations
10
States / cities
Los Angeles, California • Washington D.C., District of Columbia • Jacksonville, Florida + 6 more
Conditions
Brain Tumors
Interventions
Induction therapy (Regimen 1, Course 1, Cycle A1, Regimen 1, Course 1, Cycle A2 (Days 22 - 42), Cycle B, Regimen 1, Course 2, Intrathecal Mafosfamide, Regimen 1 Course 2, IT mafosfamide, Regimen 2, Course 1, Regimen 2, Course, 1, Cycle C1, Regimen 2, Course 2, radiation therapy
Drug · Radiation
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Up to 36 Months
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2006
U.S. locations
3
States / cities
Durham, North Carolina • Memphis, Tennessee • Houston, Texas
Conditions
Brain and Central Nervous System Tumors
Interventions
mafosfamide
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
3 Years and older
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
9
States / cities
Los Angeles, California • Washington D.C., District of Columbia • Bethesda, Maryland + 5 more
Conditions
Leukemia, Lymphoma, Meningeal Neoplasm
Interventions
Mafosfamide
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1989 – 2003
U.S. locations
1
States / cities
Bethesda, Maryland