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ClinicalTrials.gov public records Last synced Oct 9, 2026, 9:16 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 97–120 of 134 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Investigational contact lens Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of an Investigational Multifocal Lens

NCT02223754
View directory record Official record
Conditions
Presbyopia
Interventions
lotrafilcon B, etafilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
371 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
20
States / cities
Montgomery, Alabama • Mission Viejo, California • Jacksonville, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 9, 2026, 9:16 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Etafilcon A Contact Lenses Using a Novel Molding Process

NCT03605303
View directory record Official record
Conditions
Refractive Error Correction
Interventions
Test/Control, Control/Test
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Results available

Vistakon Investigational Contact Lenses Worn for Daily Wear

NCT00717249
View directory record Official record
Conditions
Myopia
Interventions
galyifilcon A control lens, galyfilcon A with a silver additive
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years and older
Enrollment
529 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
20
States / cities
Fresno, California • Mission Viejo, California • Louisville, Colorado + 17 more
Source: ClinicalTrials.gov public record
Updated May 26, 2016 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Daily Disposable Etafilcon A Cosmetic Contact Lenses

NCT04529109
View directory record Official record
Conditions
Visual Acuity
Interventions
etafilcon A investigational cosmetic lens 1, etafilcon A investigational cosmetic lens 2
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 29 Years · Female only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
2
States / cities
Jacksonville, Florida • Tyler, Texas
Source: ClinicalTrials.gov public record
Updated Nov 24, 2021 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Performance of Two Designs of Soft Toric Lenses

NCT01309867
View directory record Official record
Conditions
Myopia
Interventions
Investigational Toric Lens, PureVision Toric Lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
302 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Prototype Lenses With Experimental UV/HEV Blocker

NCT04885296
View directory record Official record
Conditions
Visual Acuity
Interventions
TRP-200, JJVC Marketed Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
228 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
12
States / cities
Jacksonville, Florida • Orange Park, Florida • Tallahassee, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2022 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate the Product Performance of a Low Add MultiFocal Soft Contact Lens

NCT01539694
View directory record Official record
Conditions
Presbyopia
Interventions
LD118033 contact lens, PureVision multifocal contact lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 30, 2020 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Results available

Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Toric Contact Lenses

NCT06461455
View directory record Official record
Conditions
Presbyopia, Astigmatism
Interventions
Lehfilcon A multifocal for astigmatism contact lenses, Samfilcon A multifocal for astigmatism contact lenses, CLEAR CARE® Cleaning & Disinfecting Solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
11
States / cities
Oakland, California • San Francisco, California • Maitland, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a New Silicone Hydrogel Contact Lens

NCT01309880
View directory record Official record
Conditions
Myopia
Interventions
Test lens, Air Optix Aqua
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2015 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Results available

Effect of FID 114675A on Lens Wettability

NCT01342107
View directory record Official record
Conditions
Contact Lens Wettability
Interventions
FID 114675A multi-purpose disinfecting solution (MPDS), Soft contact lens, Blister pack solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Apr 13, 2012 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Efficacy of an Investigational Multi-Purpose Disinfecting Solution

NCT01341977
View directory record Official record
Conditions
Healthy Contact Lens Wearers
Interventions
Alcon MPDS, ReNu Fresh MPS
Device
Lead sponsor
Alcon Research
Industry
Eligibility
Not listed
Enrollment
573 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Sep 23, 2020 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Results available

Clinical Performance of a Monthly Replacement Silicone Hydrogel Lens

NCT03586167
View directory record Official record
Conditions
Refractive Errors
Interventions
LID014341 contact lenses, Comfilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
4
States / cities
Maitland, Florida • Johns Creek, Georgia • Bloomington, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2021 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Results available

Pilot Evaluation of a New Galyfilcon A Contact Lens Compared to a Marketed Galyfilcon A Contact Lens

NCT01094730
View directory record Official record
Conditions
Myopia
Interventions
galyfilcon A prototype lens, marketed galyfilcon A lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
9
States / cities
Cupertino, California • Huntington Beach, California • Los Angeles, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a Daily Disposable Silicone Hydrogel Multifocal Contact Lens in Myopes and Hyperopes

NCT05222880
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Contact Lenses manufactured in senofilcon A C3
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
12
States / cities
Jacksonville, Florida • Maitland, Florida • Tallahassee, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Myopic Population

NCT04310566
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Contact Lens (senofilcon A c3), Dailies Total 1® Multifocal Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
7
States / cities
Jacksonville, Florida • Maitland, Florida • Pittsburg, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 19, 2022 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Clinical Performance of Daily Disposable Silicone Hydrogel Multifocal Toric Contact Lenses

NCT06377488
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Toric Contact Lens manufactured in Senofilcon A (C3) material with UV blocker / HEV filter
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
176 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
15
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate the Product Feasibility of a New Silicone Hydrogel Contact Lens

NCT01412983
View directory record Official record
Conditions
Myopia
Interventions
Bausch & Lomb Test lens, Ciba Vision soft contact lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2014 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Results available

A Safety and Effectiveness Study of a New Contact Lens Cleaning and Disinfecting Solution

NCT02701556
View directory record Official record
Conditions
Contact Lens Wear
Interventions
Complete MPS, NNR06
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
396 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Pittsburg, Kansas
Source: ClinicalTrials.gov public record
Updated Feb 8, 2022 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate the Feasibility of a High Add Multi Focal Contact Lens

NCT01518868
View directory record Official record
Conditions
Presbyopia
Interventions
Investigational contact lens, PureVision contact lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 30, 2020 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Results available

Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 2

NCT03888482
View directory record Official record
Conditions
Refractive Error, Myopia
Interventions
Verofilcon A contact lenses, Somofilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
8
States / cities
Jacksonville, Florida • Maitland, Florida • Orlando, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2020 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Results available

Effect of an Investigational Multi-Purpose Solution on Lens Moisture

NCT01341990
View directory record Official record
Conditions
Contact Lens Moisture
Interventions
FID 114675A Multi-Purpose Disinfecting Solution (MPDS), ReNu Fresh Lens Comfort Multi-Purpose Solution (MPS), Silicone Hydrogel Contact Lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Apr 13, 2012 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Results available

Feasibility of a New Silicone Hydrogel Lens

NCT01131130
View directory record Official record
Conditions
Myopia
Interventions
Investigational contact lens, Acuvue Oasys Contact Lens, Air Optix Aqua
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2014 · Synced Oct 9, 2026, 9:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of a Scleral Lens on the Anterior Chamber Depth and Minimum Rim Width

NCT03926975
View directory record Official record
Conditions
Ocular Hypertension
Interventions
Scleral Lens, No lens
Device · Other
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 60 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 29, 2021 · Synced Oct 9, 2026, 9:16 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

VisionApp - Ghosting

NCT07571538
View directory record Official record
Conditions
Diplopia, Monocular
Interventions
Proclear 1 Day Contact Lens, MyDay Contact Lens, NaturalVue Contact Lens, MiSight 1 Day Contact Lens, Investigational Contact Lens, VisionApp
Device
Lead sponsor
Indiana University
Other
Eligibility
8 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 9, 2026, 9:16 PM EDT