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Showing 1–11 of 11 matching trials from the live ClinicalTrials.gov search.
Recruiting Not applicable Interventional Accepts healthy volunteers

Wound Irrigation Comparative Effectiveness Study

NCT06379919
Conditions
Cutibacterium Acnes Contamination
Interventions
Irrisept Irrigation, Saline Irrigation Solution Delivery
Procedure
Lead sponsor
Orthopaedic Education and Research Institute (dba Hoag Orthopedics)
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Orange, California
Conditions
Urinary Tract Infection, Antibiotic, Catheter Infection
Interventions
0.05% Chlorhexidine Gluconate, Normal Saline
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Breast Cancer
Interventions
Chlorhexidine irrigation, triple antibiotic irrigation
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 81 Years · Female only
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Bladder Cancer, Urinary Tract Infection
Interventions
Irrisept® Antimicrobial Wound Lavage
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Lumbar Spine Degeneration, Cervical Spine Degeneration
Interventions
saline 0.9%, (0.05% chlorhexidine gluconate (CHG) in sterile water)
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Columbia, Missouri
Completed Not applicable Interventional Results available

Retrospective Independent Safety Review of Closed Irrisept Study

NCT05359666
Conditions
Adverse Events
Interventions
Irrisept, Standard of Care
Device
Lead sponsor
Irrimax Corporation
Industry
Eligibility
Not listed
Enrollment
592 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
17
States / cities
Tucson, Arizona • Los Angeles, California • Denver, Colorado + 14 more
Conditions
Surgical Site Infection
Interventions
IrriSept System, No Intervention - Standard of Care (SoC) only
Device · Other
Lead sponsor
Irrimax Corporation
Industry
Eligibility
18 Years and older
Enrollment
627 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
17
States / cities
Tucson, Arizona • Los Angeles, California • Denver, Colorado + 14 more
Conditions
Cesarean Section Complications, Cesarean Section; Infection
Interventions
Irrisept, Normal Saline
Device · Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older · Female only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Loma Linda, California
Completed Phase 4 Interventional Accepts healthy volunteers

Irrisept C.Acnes Study

NCT03938467
Conditions
Rate of Positive Culture Growth for C.Acnes From Specimens Obtained From the Shoulders of Patients Undergoing Primary Shoulder Arthroplasty
Interventions
Antiseptic Cleanser
Drug
Lead sponsor
Orthopaedic Associates of Michigan, PC
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Grand Rapids, Michigan
Conditions
Surgery, Surgical Site Infection, Cutibacterium Acnes, Prosthetic-joint Infection
Interventions
Povidone-Iodine, SURGX Wound Gel
Drug · Device
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Pilonidal Disease
Interventions
Irrisept (0.05% chlorhexidine gluconate), Normal Saline
Device · Other
Lead sponsor
Yosef Nasseri, MD
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Los Angeles, California