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Showing 1–24 of 26 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Ischemic Conditioning Sham Clear all
Active, not recruiting Phase 2 Interventional

RIC-NEC Randomized Controlled Trial

NCT05279664
View directory record Official record
Conditions
Necrotizing Enterocolitis
Interventions
Remote ischemic conditioning (RIC) + Standard of Care for NEC, Standard of Care for NEC
Other
Lead sponsor
The Hospital for Sick Children
Other
Eligibility
0 Weeks and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Sep 10, 2026, 5:53 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Effect of Number of Remote Limb Ischemic Conditioning Cycles on Learning Enhancement

NCT03512041
View directory record Official record
Conditions
Healthy, Young Adults
Interventions
RLIC - 5 cycles, RLIC - 4 Cycles, RLIC - 3 Cycles, Sham conditioning, Balance training, Arm training, Sequence production training
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 40 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 25, 2019 · Synced Sep 10, 2026, 5:53 PM EDT
Completed Not applicable Interventional Results available

Biochemical Effects of Remote Ischemic Pre-Conditioning on Contrast-induced Acute Kidney Injury

NCT03236441
View directory record Official record
Conditions
Contrast-induced Acute Kidney Injury
Interventions
RIPC, Sham-RIPC
Device
Lead sponsor
Oladipupo Olafiranye, MD, MS
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Sep 10, 2026, 5:53 PM EDT
Completed Not applicable Interventional

Ischemic Conditioning to Enhance Function (I-C-FUN) in Children With Cerebral Palsy

NCT04598711
View directory record Official record
Conditions
Cerebral Palsy
Interventions
RLIC, Sham Conditioning, Muscle Power training, Balance training, Treadmill Training
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
6 Years to 16 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 12, 2023 · Synced Sep 10, 2026, 5:53 PM EDT
Completed Not applicable Interventional

Ischemic Conditioning as an Intervention to Improve Motor Function in Chronic Stroke

NCT03095755
View directory record Official record
Conditions
Stroke
Interventions
Ischemic Conditioning, Sham
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 13, 2020 · Synced Sep 10, 2026, 5:53 PM EDT
Completed Not applicable Interventional

Remote Ischemic Pre-conditioning in Subarachnoid Hemorrhage

NCT02381522
View directory record Official record
Conditions
Brain Aneurysms
Interventions
Remote Ischemic Pre-conditioning, Sham RIPC
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Oct 28, 2021 · Synced Sep 10, 2026, 5:53 PM EDT
Recruiting Phase 2Phase 3 Interventional

Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial

NCT04982419
View directory record Official record
Conditions
Acute Kidney Injury, Heart Failure, Contrast Induced Nephropathy, Coronary Angiography, Percutaneous Coronary Intervention
Interventions
Remote ischemic preconditioning, Sham remote ischemic conditioning
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania • Dallas, Texas • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Sep 10, 2026, 5:53 PM EDT
Not listed Not applicable Interventional

Chronic Remote Ischemic Conditioning in Vascular Cognitive Impairment: A Dose Escalation Study

NCT06179797
View directory record Official record
Conditions
Age-related Cerebral White Matter Changes, Cognition Disorder
Interventions
remote ischemic conditioning
Device
Lead sponsor
Augusta University
Other
Eligibility
56 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Sep 10, 2026, 5:53 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Remote Ischemic Conditioning and Spinal Reflex Modulation

NCT06860464
View directory record Official record
Conditions
Healthy Young Adults
Interventions
Remote Ischemic Condtioning (RIC), Sham Conditioning, Balance training
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 40 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Sep 10, 2026, 5:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Remote Ischemic Conditioning on Hand Use in Individuals With SCI and ALS

NCT03851302
View directory record Official record
Conditions
Spinal Cord Injuries, Amyotrophic Lateral Sclerosis
Interventions
Active Remote Ischemic Conditioning, Sham Remote Ischemic Conditioning, Isometric hand exercise
Other
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Sep 10, 2026, 5:53 PM EDT
Not listed Not applicable Interventional

Remote Ischemic Conditioning Using the autoRIC

NCT03318575
View directory record Official record
Conditions
Ischemia-Reperfusion Injury
Interventions
autoRIC, autoRIC Sham
Device
Lead sponsor
CellAegis US, Inc.
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
14
States / cities
Birmingham, Alabama • Danbury, Connecticut • Jacksonville, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 30, 2018 · Synced Sep 10, 2026, 5:53 PM EDT
Not listed Not applicable Interventional

Remote Ischemic Conditioning in Abdominal Surgery

NCT03234543
View directory record Official record
Conditions
Laparotomy, Laparoscopy, Retroperitoneal Disease, Pelvis Disease, Pancreatic Diseases, Liver Diseases, Gastrointestinal Disease, Urologic Diseases, Complication of Surgical Procedure
Interventions
Remote ischemic conditioning, No Remote ischemic conditioning
Procedure
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 24, 2019 · Synced Sep 10, 2026, 5:53 PM EDT
Completed Not applicable Interventional

The Effect of Ischemic Conditioning on Strength and Ambulation in Subjects with PAD

NCT04937179
View directory record Official record
Conditions
Peripheral Arterial Disease, Peripheral Vascular Disease, Amputation, Lower Limb Amputation Knee, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury)
Interventions
Ischemic Conditioning Low - Sham Comparator, Ischemic Conditioning High - Active Comparator
Procedure
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Sep 10, 2026, 5:53 PM EDT
Completed Not applicable Interventional

Neuroprotective Effects of Remote Ischemic Preconditioning (RIPC) During Infant Cardiac Surgery

NCT01835392
View directory record Official record
Conditions
Heart Defects, Congenital
Interventions
Remote Ischemic Preconditioning, Control
Procedure · Other
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
1 Day to 6 Months
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Mar 15, 2020 · Synced Sep 10, 2026, 5:53 PM EDT
Completed Not applicable Interventional Results available

Motor and Neurophysiological Changes After Ischemic Conditioning in Individuals With Stroke

NCT05906602
View directory record Official record
Conditions
Stroke
Interventions
Real Ischemic Conditioning, Sham Ischemic Conditioning
Device
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Sep 10, 2026, 5:53 PM EDT
Completed Not applicable Interventional

Remote Ischemic Conditioning, Bimanual Skill Learning, and Corticospinal Excitability

NCT05355883
View directory record Official record
Conditions
Unilateral Cerebral Palsy, Hemiplegic Cerebral Palsy, Remote Ischemic Conditioning
Interventions
Remote Ischemic Conditioning (RIC), Sham conditioning, Hand Arm Bimanual Intensive Therapy (HABIT), Bimanual Cup Stacking Training, Balance training
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
6 Years to 16 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Sep 10, 2026, 5:53 PM EDT
Withdrawn Not applicable Interventional

Remote Ischemic PreConditioning (RIPC)

NCT03814850
View directory record Official record
Conditions
Unruptured Cerebral Aneurysm
Interventions
Standard Manual Aneroid Sphygmomanometer
Device
Lead sponsor
Sebastian Koch
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 7, 2023 · Synced Sep 10, 2026, 5:53 PM EDT
Completed Not applicable Interventional

Ischemic Conditioning Chronic Stroke Study

NCT04039399
View directory record Official record
Conditions
Stroke
Interventions
Ischemic Conditioning, Sham Ischemic Conditioning
Procedure
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 24, 2023 · Synced Sep 10, 2026, 5:53 PM EDT
Completed Not applicable Interventional

Preconditioning With Limb Ischemia for Subarachnoid Hemorrhage

NCT02411266
View directory record Official record
Conditions
Ischemic Preconditioning
Interventions
ischemic conditioning group
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 12, 2021 · Synced Sep 10, 2026, 5:53 PM EDT
Completed Not applicable Interventional

Effects of Remote Ischemic Conditioning on Bimanual Skill Learning and Corticospinal Excitability in Children With Unilateral Cerebral Palsy

NCT05777070
View directory record Official record
Conditions
Unilateral Cerebral Palsy
Interventions
Bimanual Cup Stacking Training
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
8 Years to 16 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2025 · Synced Sep 10, 2026, 5:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ischemic Conditioning Improves Walking Function Post Stroke

NCT04038697
View directory record Official record
Conditions
Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Stroke, Cardiovascular
Interventions
Ischemic Conditioning, Ischemic Conditioning Sham, Treadmill Training
Procedure
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
2
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 10, 2026, 5:53 PM EDT
Completed Not applicable Interventional Results available

Remote Ischemic Conditioning to Enhance Resuscitation (RICE) Pilot

NCT04265807
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Active Remote Ischemic Conditioning, Sham Remote Ischemic Conditioning
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Sep 10, 2026, 5:53 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Remote Limb Ischemic Conditioning to Enhance Learning and Muscle Strength in Healthy Young Adults

NCT03512028
View directory record Official record
Conditions
Healthy, Young Adults
Interventions
RLIC, Sham conditioning, Muscle strength training, Driving training, Balance training
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 40 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Sep 10, 2026, 5:53 PM EDT
Recruiting Not applicable Interventional

Blood Flow Regulation and Neuromuscular Function Post-Stroke

NCT06027294
View directory record Official record
Conditions
Stroke
Interventions
Ischemic Conditioning
Procedure
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Sep 10, 2026, 5:53 PM EDT