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Showing 1–24 of 103 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Isometric exercises Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Comparing the Effects of Pelvic Alignment Versus Diaphragmatic Breathing on Shoulder Range of Motion

NCT04255355
View directory record Official record
Conditions
Glenohumeral Internal Rotation Deficit, Pelvic Misalignment, Diaphragmatic Breathing
Interventions
Pelvic alignment and forceful expiration, Pelvic repositioning exercise, Diaphragmatic breathing exercise
Other
Lead sponsor
University of North Georgia
Other
Eligibility
18 Years to 40 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Dahlonega, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Sep 3, 2026, 11:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mechanisms of Improving Fecal Continence Muscles Motor Function

NCT06532123
View directory record Official record
Conditions
Fecal Incontinence
Interventions
continence muscles resistance device
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
340 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Sep 3, 2026, 11:02 AM EDT
Not yet recruiting Early Phase 1 Interventional Accepts healthy volunteers

tDCS for Cancer-Related Fatigue and Weakness

NCT07159100
View directory record Official record
Conditions
Cancer-related Fatigue, Neuromodulation
Interventions
Active tDCS + elbow flexion exercise, Sham tDCS + elbow flexion exercise
Device · Drug
Lead sponsor
Kessler Foundation
Other
Eligibility
40 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 7, 2025 · Synced Sep 3, 2026, 11:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exercise-induced Hypoalgesia After Comparative Forms of Exercise

NCT01883895
View directory record Official record
Conditions
Pain
Interventions
Forgionei-Barber pressure-pain stimulator, Concentric Exercise, isometric exercise
Device · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 40 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 23, 2017 · Synced Sep 3, 2026, 11:02 AM EDT
Not yet recruiting Early Phase 1 Interventional Accepts healthy volunteers

Neuro-Intermuscular Coordination Enhancement (NICE) Rehabilitation Through Human-Machine Interaction in Chronic Stroke

NCT07531264
View directory record Official record
Conditions
Chronic Stroke-related Upper-extremity Motor Impairment, Motor Module-guided Rehabilitation Targeting Impaired Intermuscular Coordination and Motor Recovery
Interventions
Neuromuscular coordination enhancement (NICE) intervention, EMG Amplitude Biofeedback Exercise
Other
Lead sponsor
University of Houston
Other
Eligibility
21 Years to 80 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2032
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 3, 2026, 11:02 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Cardiovascular Autonomic Function and Endogenous Pain Modulation

NCT03911609
View directory record Official record
Conditions
Fibromyalgia, Exercise, Pain, Autonomic Dysfunction, Physical Activity
Interventions
Exercise, Cognitive Task
Other
Lead sponsor
Marquette University
Other
Eligibility
18 Years to 75 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 10, 2019 · Synced Sep 3, 2026, 11:02 AM EDT
Withdrawn Not applicable Interventional

Mobility and Activity Training (MAT) to Optimize Outcomes for Older Adult Abdominal Surgery Patients

NCT02007876
View directory record Official record
Conditions
Gastrointestinal Malignancy
Interventions
Mobility and Activity Training
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
60 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
2
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 2, 2016 · Synced Sep 3, 2026, 11:02 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Nutritional Supplement, Eccentric Exercise and Recovery

NCT01444170
View directory record Official record
Conditions
Injury, Inflammation
Interventions
dicreatinol sulfate, placebo sugar pill
Dietary Supplement · Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 25 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 14, 2019 · Synced Sep 3, 2026, 11:02 AM EDT
Completed Not applicable Interventional

Yoga Versus Exercises for Managing OA

NCT02525341
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Hatha yoga, Aerobic and strengthening exercises, General education
Other
Lead sponsor
University of Minnesota
Other
Eligibility
60 Years to 100 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 6, 2019 · Synced Sep 3, 2026, 11:02 AM EDT
Completed Not applicable Interventional

Project 4B: Lower Extremity Strength Training in ICU Patients

NCT02467023
View directory record Official record
Conditions
Sepsis
Interventions
Muscle stimulation with Niveus medical stimulator, measurement of maximal isometric twitch strength, Muscle Biopsy, Muscle Biopsy Medication: Lidocaine, Muscle Biopsy Medication: Versed, Muscle Biopsy Medication: Fentanyl, Blood and Urine Sampling, ineffective muscle stimulation
Device · Procedure · Drug + 1 more
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 18, 2018 · Synced Sep 3, 2026, 11:02 AM EDT
Completed Phase 4 Interventional Results available

Maintain Respiratory Muscle Function and Reduce Pneumonia Risk in Cancer Patients

NCT03469271
View directory record Official record
Conditions
Cancer
Interventions
1,25 (OH)2 D3, Inspiratory isometric resistance training, Oral Placebo, Sham Inspiratory Isometric Resistance Training, Threshold Inspiratory Muscle Trainer (IMT)
Drug · Other · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 25, 2023 · Synced Sep 3, 2026, 11:02 AM EDT
Recruiting Not applicable Interventional

A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects

NCT06843577
View directory record Official record
Conditions
Elevated Blood Pressure, Hypertension
Interventions
Zona Plus Device, Relaxing Music App
Device · Other
Lead sponsor
Zona Health, Inc
Industry
Eligibility
22 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
10
States / cities
Valley Village, California • West Hills, California • Plantation, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 3, 2026, 11:02 AM EDT
Completed Phase 2 Interventional Results available

Twice Weekly Steroids and Exercise as Therapy for DMD

NCT04322357
View directory record Official record
Conditions
Duchenne Muscular Dystrophy (DMD)
Interventions
Prednisone, Exercise Training on standard steroid regimen, Exercise training on twice-weekly steroids
Drug · Behavioral
Lead sponsor
University of Florida
Other
Eligibility
5 Years to 9 Years · Male only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 3, 2026, 11:02 AM EDT
Completed Not applicable Interventional

TeleRehabilitation Following ACL Reconstruction

NCT04541940
View directory record Official record
Conditions
ACL Injury
Interventions
Telerehabilitation Therapy, In-person Rehabilitation Therapy
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 40 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 30, 2022 · Synced Sep 3, 2026, 11:02 AM EDT
Terminated Not applicable Interventional Results available

Effect of Electromyographic Biofeedback on Quadriceps Neuromuscular Function in Patients With Quadriceps Inhibition

NCT02095223
View directory record Official record
Conditions
Knee Injuries
Interventions
Electromyographic Biofeedback, Traditional Exercise
Device · Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 40 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Sep 3, 2026, 11:02 AM EDT
Completed Not applicable Interventional

Physical Therapy for Anal Incontinence

NCT03252951
View directory record Official record
Conditions
Anal Incontinence, Fecal Incontinence
Interventions
Eccentric Training, Concentric Training, Isometric Training, Biofeedback
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
22 Years and older · Female only
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 24, 2022 · Synced Sep 3, 2026, 11:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Isometric Exercise and Endogenous Pain Inhibition

NCT03778476
View directory record Official record
Conditions
Fibromyalgia
Interventions
Isometric Exercise
Other
Lead sponsor
Marquette University
Other
Eligibility
18 Years to 75 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 23, 2021 · Synced Sep 3, 2026, 11:02 AM EDT
Terminated Not applicable Interventional

Clinical Prediction Rule for Clinical Lumbar Instability

NCT01085448
View directory record Official record
Conditions
Low Back Pain
Interventions
Core Stabilization
Other
Lead sponsor
Drexel University
Other
Eligibility
21 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • West Chester, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 4, 2013 · Synced Sep 3, 2026, 11:02 AM EDT
Completed Phase 2 Interventional

Muscle Composition and Function for Swallowing in Head/Neck Cancer Patients

NCT00796952
View directory record Official record
Conditions
Head & Neck Cancer
Interventions
focused attention sessions, Valchuff, Pharyngocise
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 90 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 19, 2011 · Synced Sep 3, 2026, 11:02 AM EDT
Completed Not applicable Interventional

Specific and Shared Mechanisms Associated With Treatment for Chronic Neck Pain

NCT05940012
View directory record Official record
Conditions
Chronic Neck Pain
Interventions
Manual Therapy
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 17, 2025 · Synced Sep 3, 2026, 11:02 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Influence of Exercise Type, Pain Mechanisms, and Biopsychosocial Contributions to Pain Relief in Those With Fibromyalgia

NCT03778385
View directory record Official record
Conditions
Fibromyalgia
Interventions
Exercise
Other
Lead sponsor
Marquette University
Other
Eligibility
18 Years to 75 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 6, 2022 · Synced Sep 3, 2026, 11:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Aging and the Mitochondrial Response to Exercise Training, Measured by Noninvasive 31P Magnetic Resonance Spectroscopy

NCT04799171
View directory record Official record
Conditions
Physical Activity
Interventions
Isometric Contraction Exercise - Young Adults (Age group 18-39), Isometric Contraction Exercise - Middle Age Adults (Age group 40-59), Isometric Contraction Exercise - Old Adults (Age group >60)
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years and older
Enrollment
352 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Sep 3, 2026, 11:02 AM EDT
Recruiting Phase 1Phase 2 Interventional

Treating Chronic Cervicogenic Head and Neck Pain

NCT05617365
View directory record Official record
Conditions
Cervicogenic Headache, Neck Pain, Posterior
Interventions
Osteopathic Manipulative Therapy and Exercise Therapy
Combination Product
Lead sponsor
Michigan State University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Sep 3, 2026, 11:02 AM EDT
Completed Phase 2 Interventional

Muscle Strengthening Device for Knee Osteoarthritis

NCT00007241
View directory record Official record
Conditions
Osteoarthritis
Interventions
Isometric exercise
Device
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2002
U.S. locations
6
States / cities
Trumbull, Connecticut • Moorestown, New Jersey • Rochester, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 3, 2007 · Synced Sep 3, 2026, 11:02 AM EDT