Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 11, 2026, 12:21 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 289–312 of 1,141 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Isotonic solution Clear all

Conditions: HIV Infections, Streptococcus Pneumoniae
Interventions: pneumococcal conjugate vaccine, pneumococcal polysaccharide vaccine; Biological
Lead sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine; Other
Eligibility: 18 Years to 60 Years
Enrollment: 275 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2013
U.S. locations: 6
States / cities: San Diego, California • Washington D.C., District of Columbia • Tripler AMC, Hawaii + 3 more

Conditions: Asthma
Interventions: Magnesium Sulfate, Heptahydrate, 0.9% saline; Drug
Lead sponsor: University of Utah; Other
Eligibility: 2 Years to 17 Years
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 3
States / cities: Columbus, Ohio • Philadelphia, Pennsylvania • Salt Lake City, Utah

Conditions: Invasive Candidiasis
Interventions: Caspofungin, Normal Saline; Drug
Lead sponsor: Mycoses Study Group; Network
Eligibility: 18 Years and older
Enrollment: 222 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 12
States / cities: Birmingham, Alabama • Los Angeles, California • Denver, Colorado + 8 more

Conditions: Post-operative Surgical Pain
Interventions: Nerve Block with ropivicaine 0.5% Injectable Solution, Nerve Block with Placebo sham control of 0.9% Normal Saline; Procedure
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 65 Years
Enrollment: 49 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Safety and Tolerability in Healthy Volunteers
Interventions: NLY01; Drug
Lead sponsor: Neuraly, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 96 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Acute Kidney Injury
Interventions: Amino Acids, Placebo; Drug
Lead sponsor: Stanford University; Other
Eligibility: 1 Day to 18 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Hemorrhage/Blood Loss During Myomectomies, Fibroids
Interventions: Tranexamic Acid, Saline Solution; Drug · Other
Lead sponsor: George Washington University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Children, Only, Tonsillar Hypertrophy, Adenoid Hypertrophy
Interventions: Lidocaine Iv, Saline Solution; Drug
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 4 Years to 10 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Complex Regional Pain Syndrome
Interventions: Ketamine, IV NSS, Normal Saline; Drug · Other
Lead sponsor: Drexel University College of Medicine; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Diabetes, Hypertension, Obesity
Interventions: Intralipid 20%, Normal Saline, Oral fat load; Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Post-Traumatic Headache
Interventions: Metoclopramide, Diphenhydramine, Normal saline; Drug
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Overactive Bladder
Interventions: botulinum toxin Type A, Normal Saline (Placebo); Biological · Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Healthy
Interventions: Tolvaptan, Hypertonic saline infusion; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 21 Years to 55 Years · Male only
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Kidney Injury
Interventions: 0.9% Sodium Chloride (Placebo), Sodium Bicarbonate; Drug
Lead sponsor: Community Medical Center, Scranton, PA; Other
Eligibility: 18 Years and older
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Scranton, Pennsylvania

Conditions: COVID-19
Interventions: Zofin, Placebo; Drug · Other
Lead sponsor: ZEO ScientifiX, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 4
States / cities: Newport Beach, California • North Hollywood, California • Miami, Florida + 1 more

Conditions: Anesthesia, Local
Interventions: AG-920, Placebo; Drug
Lead sponsor: American Genomics, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Newport Beach, California

Conditions: Renal Failure Congenital, Congenital Renal Anomaly Nos, Renal Agenesis and Dysgenesis, Lower Urinary Tract Obstructive Syndrome
Interventions: Lactated Ringers Solution for Injection; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: Not listed
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2029
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Pain, Migraine Disorders
Interventions: PF-04427429, Normal saline; Biological · Other
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 3
States / cities: Miami, Florida • Dallas, Texas

Conditions: Dental Pain
Interventions: Bupivacaine liposome, Placebo; Drug
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 166 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Healthy Participants
Interventions: CDX-622, Normal Saline; Drug
Lead sponsor: Celldex Therapeutics; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 85 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Tempe, Arizona

Conditions: Schizophrenia, Psychotic Disorders
Interventions: Siltuximab, normal saline; Drug
Lead sponsor: Brian Miller; Other
Eligibility: 18 Years to 55 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2023
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Raynaud Phenomenon
Interventions: AbobotulinumtoxinA, Saline solution; Drug · Other
Lead sponsor: University of Central Florida; Other
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Surgery, Infection
Interventions: Polymyxin B in Normal Saline, Placebo: Normal Saline; Drug · Other
Lead sponsor: Indiana University; Other
Eligibility: 18 Years to 88 Years
Enrollment: 190 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Muscle Atrophy, Surgery, Knee Injuries and Disorders, Complication of Surgical Procedure, Trauma
Interventions: Aveed 750 MG in 3 ML IM Injection, Normal Saline 3 ML IM Injection; Drug · Other
Lead sponsor: The Stone Research Foundation for Sports Medicine and Arthritis; Other
Eligibility: 18 Years to 65 Years · Male only
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: San Francisco, California

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Pneumococcal Conjugate Vaccination in HIV in Comparison to Polysaccharide Vaccine Boosting

Timely Intravenous Magnesium for Asthma in Children

Randomized Study of Caspofungin Prophylaxis Followed by Pre-emptive Therapy for Invasive Candidiasis in the Intensive Care Unit (ICU)

Regional Anesthesia (Supra-Orbital and Infra-Orbital Nerve Block) (SION) for Pain Management in Trans-sphenoidal Hypophysectomy

A Phase 1 Study to Assess the Safety of NLY01 in Healthy Subjects

Amino Acids for Cardiac Surgery Associated AKI

Use of Intravenous Tranexamic Acid During Myomectomy

Lidocaine Infusion for Pain Relief in Children Scheduled for Tonsillectomy and Adenoidectomy

Double Blind Placebo Controlled Study of Outpatient Intravenous Ketamine for the Treatment of CRPS

FFA Hypertension and Inflammation in Lean and Obese Subjects

Metoclopramide for Post Traumatic Headache

Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Neurogenic Overactive Bladder

Effects of Tolvaptan in Healthy Adults

Prevention of Acute Kidney Injury in Cardiac Surgery Patients

Zofin to Treat COVID-19 Long Haulers

A Study of the Safety and Anesthetic Effect of AG-920 Topical Ophthalmic Solution

Serial Amnioinfusions as Regenerative Therapy for Pulmonary Hypoplasia

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study Of PF-04427429 In Healthy Women Volunteers

Evaluation of EXPAREL for Prolonged Postsurgical Analgesia in Subjects Undergoing Third Molar Extraction

A Phase I Study of CDX-622

Siltuximab in Schizophrenia

The Effect of Abobotulinum Toxin A on the Symptoms of Raynaud's Phenomenon

Antibiotic Irrigation for Pancreatoduodenectomy

Use of Testosterone to Prevent Post-Surgical Muscle Loss - Pilot Study