Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 12, 2026, 12:25 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 409–432 of 1,141 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Isotonic solution Clear all

Conditions: Sleep Restriction
Interventions: Ketoconazole Pill (also known as nizoral), Ganirelix, Dexamethasone Pill, Dexamethasone injection, Cosyntropin Injectable Product, Recombinant Human Luteinizing Hormone (also known as luveris), Hydrocortisone Injection (also known as solu-cortef), Gonadorelin (also known as Lutrepulse), Corticorelin (also known as Acthrel), Placebo oral tablet, Saline Solution, Saline solution for injection; Drug
Lead sponsor: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center; Other
Eligibility: 60 Years to 80 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Torrance, California

Conditions: Spine Surgery, Back Pain
Interventions: High Dose Tranexamic acid, Low Dose Tranexamic acid, Tranexamic acid Topical, Normal saline; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years to 80 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: Delirium, Sleep
Interventions: Dexmedetomidine, Placebo; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 50 Years and older
Enrollment: 522 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Ventral Hernia Repair
Interventions: Gemcitabine/ clindamycin, Normal saline; Drug
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Greenville, South Carolina

Conditions: Pain
Interventions: IV acetaminophen, placebo; Drug
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 75 Years · Female only
Enrollment: 183 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Osteoporotic Fractures
Interventions: Teriparatide Prefilled Syringe, Placebo; Drug
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 65 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Lower Eyelid Steatoblepharon
Interventions: POLAT-001, Placebo; Drug
Lead sponsor: Peregrine Ophthalmic; Industry
Eligibility: 22 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 3
States / cities: Newport Beach, California • Coral Gables, Florida • Pflugerville, Texas

Conditions: Preterm Birth
Interventions: 17-alpha-hydroxyprogesterone caproate injectable, Placebo; Drug
Lead sponsor: Obstetrix Medical Group; Industry
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 321 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2009
U.S. locations: 18
States / cities: Phoenix, Arizona • Tucson, Arizona • Laguna Hills, California + 13 more

Conditions: Infections, Meningococcal
Interventions: MenABCWY-2Gen low dose vaccine, MenABCWY-2Gen high dose vaccine, Placebo, MenB vaccine, MenACWY vaccine; Combination Product · Biological
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 10 Years to 50 Years
Enrollment: 1,440 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 12
States / cities: Colorado Springs, Colorado • Longmont, Colorado • Doral, Florida + 9 more

Conditions: Pain
Interventions: Lidocaine, Placebo; Drug
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 2
States / cities: Gainesville, Florida

Conditions: Prostatic Neoplasms
Interventions: Pembrolizumab, Docetaxel, Prednisone, Placebo, Dexamethasone; Biological · Drug
Lead sponsor: Merck Sharp & Dohme LLC; Industry
Eligibility: 18 Years and older · Male only
Enrollment: 1,030 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 28
States / cities: Mobile, Alabama • Fullerton, California • Los Angeles, California + 24 more

Conditions: Methamphetamine Abuse
Interventions: normal saline, ch-mAb7f9; Biological
Lead sponsor: InterveXion Therapeutics, LLC; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Overland Park, Kansas

Conditions: Aging
Interventions: Ascorbic Acid, Normal Saline; Other
Lead sponsor: University of Delaware; Other
Eligibility: 18 Years to 79 Years
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Osteoarthritis
Interventions: Lactated Ringer, Placebo; Drug
Lead sponsor: West Virginia University; Other
Eligibility: 18 Years and older
Enrollment: 52 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Morgantown, West Virginia

Conditions: Infertility, Infertility, Female, Infertility, Male
Interventions: Saline Solution for Injection, Leuprolide Acetate; Drug
Lead sponsor: Maimonides Medical Center; Other
Eligibility: 18 Years to 40 Years · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Otitis
Interventions: Saline, Fentanyl, Dexmedetomidine; Drug
Lead sponsor: Children's National Research Institute; Other
Eligibility: 6 Months to 6 Years
Enrollment: 101 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Obesity
Interventions: Normal Saline 0.9% Infusion Solution Bag; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Circulatory Perfusion Disorder, Congenital Heart Disease, Single-ventricle
Interventions: Vasopressin, Arginine, Placebo; Drug
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 3 Weeks to 18 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Melanoma
Interventions: Intismeran autogene, Pembrolizumab, Placebo; Biological · Other
Lead sponsor: Merck Sharp & Dohme LLC; Industry
Eligibility: 18 Years and older
Enrollment: 1,089 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2030
U.S. locations: 34
States / cities: Springdale, Arkansas • Los Angeles, California • San Francisco, California + 27 more

Conditions: Pain
Interventions: Bupivacaine, Normal Saline; Drug · Other
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Pain
Interventions: Fentanyl, saline; Drug
Lead sponsor: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Torrance, California

Conditions: Sepsis, Severe Sepsis
Interventions: Intravenous fluid; Drug
Lead sponsor: Christiana Care Health Services; Other
Eligibility: 18 Years and older
Enrollment: 142 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 5
States / cities: Newark, Delaware • Boston, Massachusetts • Detroit, Michigan + 2 more

Conditions: Headache, Intranasal Ketamine
Interventions: Ketamine, Normal saline, Metoclopramide, Ketorolac, Dexamethasone, Benadryl; Drug
Lead sponsor: Brooke Army Medical Center; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Hyperlactatemia
Interventions: Lactated Ringer Solution, Normal Saline; Drug
Lead sponsor: University Medical Center of Southern Nevada; Other
Eligibility: 18 Years to 64 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Las Vegas, Nevada

Search by objective public record fields.

Hormonal Mechanisms of Sleep Restriction - Axis Study in Older Men and Postmenopausal Women

Combined IV and Topical TXA in Major Spine Surgery

Investigation of Sleep in the Intensive Care Unit

Reducing INfection at the Surgical SitE With Antibiotic Irrigation During Ventral Hernia Repair (RINSE Trial)

IV Acetaminophen for Postoperative Pain Analgesia After Laparoscopic Hysterectomy

PTH(1-34) and Pelvic Fracture Healing - a Randomized Controlled Trial

Assess the Safety, Tolerability and Efficacy of Latanoprost Liposome for Lower Eyelid Steatoblepharon

17OHP for Reduction of Neonatal Morbidity Due to Preterm Birth (PTB) in Twin and Triplet Pregnancies

A Study on the Safety, Effectiveness and Immune Response of Meningococcal Combined ABCWY Vaccine in Healthy Adolescents and Adults

Lidocaine For Treatment of Post-operative Pain From Donor Sites Following Burn Injury.

Study of Pembrolizumab (MK-3475) Plus Docetaxel Versus Placebo Plus Docetaxel in Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-921/KEYNOTE-921)

Safety Study of Ch-mAb7F9 for Methamphetamine Abuse

Mechanisms of Impaired Brain Blood Flow With Aging

Does Fluid Replacement From Preoperative NPO Status Improve Postoperative Recovery

GnRH Agonist at Embryo Transfer: IVF Outcomes

Dexmedetomidine vs Fentanyl for BMT

The Natriuretic Peptide Response to Saline Infusion

Early Use of Vasopressin in Post-Fontan Management

A Clinical Study of Intismeran Autogene (V940) Plus Pembrolizumab in People With High-Risk Melanoma (V940-001)

Pain Relief at Iliac Crest Bone Harvest Sites in Spine Surgery Using Bupivacaine

Intranasal Fentanyl as an Analgesic for Cystoscopic Procedures

Preemptive Resuscitation for Eradication of Septic Shock

"THINK Trial: Treatment of Headache With IntraNasal Ketamine: A Randomized Controlled Trial Evaluating the Efficacy of Intranasal Ketamine Versus Standard Therapy in the Management of Primary Headache Syndromes in the Emergency Department"

Does Intravenous Lactated Ringer Solution Raise Measured Serum Lactate?